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Neurodevelopmental and Behavioral Pediatrics - Research

We have been one of the multisite locations of the Autism Treatment Network (ATN) since January 2008. As part of the ATN, our patients with autism spectrum disorders (ASD) are eligible to be entered into a registry designed to track co-occurring medical and psychiatric conditions and treatments. We also participate in studies through the Autism Intervention Research – Physical Health Network (AIR-P), which is funded by HRSA via the Combating Autism Act Initiative (CAAI). We are collaborating with other ATN sites on studies that involve nutrition, sleep, iron metabolism, and creatine deficiency, to name a few. We also participate in a multisite, case-cohort study of the etiology of autism, which is funded by the CDC.

The eXtraordinarY Kids Clinic has a grant to evaluate genotype-phenotype correlations in individuals with sex chromosome aneuploidy and will establish a repository of DNA for future genetic studies. We will also study the behavioral and motor effects of testosterone replacement therapy in adolescent males with XXY and XXYY syndromes.

We are a member of the National Fragile X Foundation’s Fragile X Clinical and Research Consortium, which was recently funded by the CDC to develop a registry of subjects with Fragile X for the purpose of tracking medical and behavioral features and to facilitate future clinical trials.

We also have funding through the Colorado Clinical Translational Science Institute, funded by NIH, to evaluate barriers social-emotional screening in a Latino population.

Drs. Friedman, Reynolds, and Tartaglia are also members of the Intellectual and Developmental Disabilities Research Center (IDDRC) faculty.

Faculty Research Interests

Dr. William Campbell has interests in early identification, diagnosis, and treatment of developmental disorders, particularly autism and related disorders. He serves as medical consultant for Early Intervention Colorado within the Colorado Department of Human Services, Division for Developmental Disabilities. Dr. Sandra Friedman has interests in developmental outcome of children with special health care needs, end-of life care for children with intellectual and developmental special needs, children with autism spectrum disorders, and developmental screening. Dr. Edward Goldson has interests in the clinical care of children with special health care needs. His research focus most recently has been in the area of autism and Down syndrome. In the past, although these are continued interests, he has done work in Fragile X and newborn follow-up. Dr. Kimberly Johnson has interest in children with autism spectrum disorders, particularly understanding gut microbiomes in this group of children. Dr. Ann Reynolds has interests in research related to sleep, nutrition, and gastrointestinal disorders in children with autism spectrum disorders. Dr. Nicole Tartaglia has ongoing research projects addressing the clinical phenotype of children with sex chromosome variations and has recently begun a project that evaluates the impact of testosterone replacement on executive function and behavior in individuals with Klinefelter’s syndrome.