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Developmental Biology
University of Colorado School of Medicine
RC1 North, Rm P18-4131
Mailstop 8313
12800 E. 19th Avenue
Aurora, CO 80045
Phone: 303-724-4349

Children's Hospital Colorado - ​​​​


Welcome to Developmental Biology

The Section of Developmental Biology in the Department of Pediatrics provides insight into the underlying causes of human birth defects and diseases through basic scientific research.

Current areas of research emphasis include:

  • development of the nervous system
  • formation of the blood-brain barrier
  • facial development

Researchers use animal models to investigate causes of developmental disease with the goal of finding preventative strategies or effective therapies.

Children’s Hospital Colorado Research Institute and the Gates Frontier Fund have helped to launch and establish the Section of Developmental Biology.





  • Bruce Appel, PhD., Caleb Doll, PhD., Santos Franco, PhD. and Ethan Hughes, PhD., recently received a two-year NIH award entitled, "Mechanisms of Neuron-Glia Synaptic Communication".

  • The Santos Franco lab recently published a manuscript entitled, "The Dorsal Wave of Neocortical Oligodendrogenesis Begins Embryonically and Requires Multiple Sources of Sonic Hedgehog" in the Journal of Neuroscience.

  • Emily Bates, PhD, recently received a 5-year award from the National Institute of Dental and Craniofacial Research​ for a project entitled, "Ion channel mediated control of morphogen signaling for craniofacial development in mammals".

  • The Sections of Developmental Biology and Cardiology have initiated an open-rank faculty search for a cardiovascular developmental biologist​.

  • Julie Siegenthaler, PhD, and her research team received word that their manuscript entitled, "Retinoic acid is required for neural stem and progenitor cell proliferation in the adult hippocampus" has been accepted for publication in Stem Cell Reports

  • Emily Bates, PhD, gave a talk entitled, "An unexpected node in BMP signaling, K+ channels" at the Craniofacial Morphogenesis and Tissue Regeneration Gordon Conference in Il Cioco, Italy, in February 2018.

  • Emily Bates, PhD, just published in Developmental Biology on K+ channel function and BMP signaling in facial development.