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MS/Neuroimmunology

Clinical Research



If you think you may qualify for one of these studies, please contact Professional Research Assistant (PRA) below for more information.

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COMIRB # Title (Please click on the title to see approved advertisement) Principal Investigator PRA
15-0293 A Double-Blind, Placebo-Controlled, Single Ascending Dose Intravenous Infusion Study of rHIgM22 in Subjects with Multiple Sclerosis Immediately Following a Relapse Alvarez, Enrique, MD Nicola Haakonsen
303-724-4644
Eligibility and Information
12-0968 Rocky Mountain Multiple Sclerosis Center (RMMSC) Biorepository for the Study of Neuroimmunological Disorders Alvarez, Enrique, MD Nicola Haakonsen
303-724-4644
Please contact PRA for eligibility and information
14-0598 A Multicenter, Randomized, Addition to Baseline Treatment, Double-blind, Placebo-controlled, Phase 3 Study to Evaluate the Efficacy and Safety of SA237 in Patients With Neuromyelitis Optica (NMO) and NMO Spectrum Disorder (NMOSD) Bennett, Jeffrey L., MD, PhD Nicola Haakonsen
303-724-4644
Eligibility and Information
13-0388 A Phase IV Trial of Neuroprotection with ACTH in Acute Optic Neuritis Bennett, Jeffrey L., MD, PhD Nicola Haakonsen
303-724-4644
Eligibility and Information
14-0926 A Phase 2/3, Double-masked, Placebo-controlled Study with Open-Label Period to Evaluate the Efficacy and Safety of MEDI-551 in Adult Subjects with Neuromyelitis Optica and Neuromyelitis Optica Spectrum Disorders Bennett, Jeffrey L., MD, PhD Nicola Haakonsen
303-724-4644
Eligibility and Information
13-3181 Collaborative International Research in Clinical and Longitudinal Experience for Neuromyelitis Optica (NMO) Studies (CIRCLES) Bennett, Jeffrey L., MD, PhD Nicola Haakonsen
303-724-4644
Please contact PRA for eligibility and information
08-0613 The role of TH40 cell in Multiple Sclerosis and Type 1 Diabetes Corboy, John R., MD Nicola Haakonsen
303-724-4644
Please contact PRA for eligibility and information
12-1522 A 12-month, randomized, rater- and dose-blinded study to compare the efficacy and safety of fingolimod 0.25 mg and 0.5 mg administered orally once daily with glatiramer acetate 20 mg administered subcutaneously once daily in patients with relapsing-remitting multiple sclerosis Corboy, John R., MD Nicola Haakonsen
303-724-4644
Eligibility and Information
12-1388 A DOUBLE-BLIND, PLACEBO CONTROLLED TRIAL OF ESTRIOL TREATMENT IN WOMEN WITH MULTIPLE SCLEROSIS: EFFECT ON COGNITION. Corboy, John R., MD Nicola Haakonsen
303-724-4644
Eligibility and Information
09-0952 Rocky Mountain MS Center Tissue Bank Corboy, John R., MD Nicola Haakonsen
303-724-4644
Please contact PRA for eligibility and information
Vestibular rehabilitation for persons with Multiple Sclerosis: what benefits are possible Jeffrey Hebert, PT, PhD Nicola Haakonsen
303-724-4644
Eligibility and Information
13-2482 Improving bladder care for patients with Multiple Sclerosis. Developing a systematic approach for the assessment and diagnosis of neurogenic bladder in Multiple Sclerosis (MS) patients will result in improved bladder care and health related outcomes Miravalle, Augusto A., MD Nicola Haakonsen
303-724-4644
Please contact PRA for eligibility and information
13-2927 Does Long-Term Natalizumab (NTZ) Therapy Normalize Brain Atrophy Rates and Quality of Life (QOL) in Relapsing Remitting Multiple Sclerosis (RRMS)? A Longitudinal Study Using Whole Brain, Neocortical and Subcortical Atrophy Rates and Patient Reported Outcomes (PROs) Miravalle, Augusto A., MD Nicola Haakonsen
303-724-4644
Please contact PRA for eligibility and information
15-1086 Safety and Efficacy of ADS-5102 (amantadine HCl) Extended Release Capsules in Patients with Multiple Sclerosis and Walking Impairment Schreiner, Teri L., MD, MPH Nicola Haakonsen
303-724-4644
Eligibility and Information
15-0568 A Multicenter, Double-Blind, Placebo-Controlled Study of Montelukast on Gastrointestinal Tolerability in Patients With Relapsing Forms of Multiple Sclerosis Receiving TECFIDERA® (Dimethyl Fumarate) Delayed-Release Capsules Schreiner, Teri L., MD, MPH Nicola Haakonsen
303-724-4644
Eligibility and Information
13-2897 Cross-Sectional Study of MSDx Complex-1 Association with Gadolinium Enhancing Lesions in Relapsing-Remitting Multiple Sclerosis Schreiner, Teri L., MD, MPH Nicola Haakonsen
303-724-4644
Eligibility and Information
14-0388 Medication Adherence in Pediatric Multiple Sclerosis Schreiner, Teri L., MD, MPH Nicola Haakonsen
303-724-4644
Please contact PRA for eligibility and information
13-2897 A Multicenter, Global, Observational Study to Collect Information on Safety and to Document the Drug Utilization of Tecfidera™ (Dimethyl Fumarate) When Used in Routine Medical Practice in the Treatment of Multiple Sclerosis (ESTEEM) Schreiner, Teri L., MD, MPH Nicola Haakonsen
303-724-4644
Eligibility and Information
12-1084 Environmental and Genetic Risk Factors for Pediatric Multiple Sclerosis Schreiner, Teri L., MD, MPH Nicola Haakonsen
303-724-4644
Please contact PRA for eligibility and information
12-1102 Pediatric Multiple Sclerosis and other Demyelinating Diseases Database (PeMSDD Database) Schreiner, Teri L., MD, MPH Nicola Haakonsen
303-724-4644
Please contact PRA for eligibility and information
13-2708 Two-year, Double-blind, Randomzied, Multicenter, Active-controlled Study to Evaluate Safety and Efficacy of Oral Fingolimod Versus Interferon Beta-1a i.m. in Pediatric Patients With Multiple Sclerosis Schreiner, Teri L., MD, MPH Nicola Haakonsen
303-724-4644
Eligibility and Information
Comparative Effects of Glatiramer Acetate and BG0012 on lymphocyte survival and metabolism Vollmer, Timothy L., MD
Greg Owens, PhD
Nicola Haakonsen
303-724-4644
Please contact PRA for eligibility and information
14-2032 A Multinational, Multicenter, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Study to Evaluate the Efficacy, Safety, and Tolerability of Once Daily Oral Administration of Laquinimod (0.6 or 1.5 mg) in Patients with Primary Progressive Multiple Sclerosis (PPMS) Vollmer, Timothy L., MD Nicola Haakonsen
303-724-4644
Eligibility and Information
14-1101 Determining if B cell-astrocyte interactions initiate CNS pathology in Multiple Sclerosis Vollmer, Timothy L., MD
Wendy Macklin, MD
Nicola Haakonsen
303-724-4644
Please contact PRA for eligibility and information
14-0844 Exploring the mechanism of action of laquinimod on B lymphocytes in astrocytes in multiple sclerosis Vollmer, Timothy L., MD
Wendy Macklin, MD
Nicola Haakonsen
303-724-4644
Please contact PRA for eligibility and information