Dr Ridgway came to Colorado in 1985 from the Massachusetts General Hospital in Boston Massachusetts where he was head of the Thyroid Unit to become Head of the Division of Endocrinology, Metabolism, and Diabetes (1985-2007). He is the past President of the American Thyroid Association (1996-97) and past President of the Endocrine Society (2003-2004). Based at the University of Colorado Health Sciences Center, his basic research centers on thyrotropin (TSH), the major regulator of the thyroid gland. His laboratory utilizes state-of-the-art molecular techniques to understand the developmental and regulatory factors controlling the alpha and beta subunits of thyrotropin. In human disease, Dr. Ridgway's laboratory has a long interest in the production of the glycoprotein pituitary hormones by pituitary tumors. Originally these tumors were called non-functioning because they were not associated with classical clinical syndromes. However, improved methods have shown glycoprotein hormone production in 15-30% of pituitary tumors. In addition, Dr. Ridgway has a major interest in the peripheral actions of thyroid hormones on a variety of the processes in human disorders of the thyroid gland. He is particularly interested in alterations in cardiac, brain, pulmonary, skeletal muscle, hepatic and adipocyte function in patients with thyroid dysfunction, and their correction by appropriate therapies