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The core offers a wide variety of pre-clinical models in rats and mice, from development to analysis.

Our main therapeutic areas are cardiovascular, renal, and pulmonary. We utilize state-of-the-art data acquisition platforms, and offer a comprehensive suite of research services ranging from pharmacokinetics, target-based functional screens through model validation, and complex proof-of-concept studies.​​​​

  • Cardiac Imaging
  • 3D Imaging
  • Vasculature Imaging
  • Tumor Imaging
  • Ultrasound-guided I​njections
  • Contrast Imaging
  • Thoracic Imaging​
  • Thoracic Aorta Constriction (TAC)
  • Left Anterior Coronary Artery Ligation (MI)
  • Unilateral and 5/6 Nephrectomy
  • Pulmonary Artery Ligation
  • LV-RV Pressure Volume Loops
  • Pulmonary Arterial Pressure
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Systolic Function

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    Ejection Fraction/Fractional Shortening
    LV Dimensions and Wall Thickness
    Cardiac Output/Stroke Volume

Diastolic Function

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    Pulmonary Vein Blood Flow
    Mitral Valve Blood Flow (E/A)
    Mitral Valve Tissue Movement (E'/A')

Hypertension

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    Pulmonary Vein Blood Flow/Diameter
    RV Wall Thickness
    Tricuspid Valve Blood Flow

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The Vevo® platform was the world’s first commercially available high-frequency array based ultrasound imaging system and has since emerged as the gold standard in small animal anatomical and functional in vivo imaging. The Vevo Family of high-frequency ultrasound products enables the researcher to obtain in vivo anatomical, functional, physiological and molecular data simultaneously, in real-time and with a resolution down to 30 µm. ​​

For more information on pricing and scheduling, please contact Maria Cavasin at maria.cavasin@ucdenver.edu​ or 303-724-5424.