Skip to main content
Sign In

Samuel Gubbels, MD, FACS

Associate Professor

​Clinical Office:

1635 N. Aurora Court, 6th Floor

Aurora, CO 80045

Appointments: 720-848-2820


Academic Office:

12631 E. 17th Avenue, B205

Aurora, CO 80045

Phone: 303-724-1950

Fax: 303-724-1961



Hospital Affiliations:

University of Colorado Hospital

Children's Hospital Colorado

Denver Health Medical Center

Denver Veteran's Administration Medical Center


​​Samuel Paul Gubbels, MD, is an Associate Professor in the Department of Otolaryngology. He recently joined the University of Colorado after a seven year period as a faculty member at the University of Wisconsin – Madison. Dr. Gubbels has a specialty clinical practice dedicated to managing hearing loss, balance disorders and diseases of the skull base. In addition, he runs a research program focused on evaluating stem cells as a means to better understand and treat hearing loss in humans. Hearing loss is an exceedingly common problem worldwide with severe to profound deafness affecting over 300 million individuals worldwide. 

Clinical Interests: 

Medical and surgical management of diseases of the ear and skull base. Particular interests cochlear implantation in children and adults, acoustic neuroma, otosclerosis, skull base tumors, facial nerve disorders, congenital ear disorders and the treatment of vertigo.

Specialty Training: Neurotology



​Medical School

MD, University of Arizona College of Medicine (2000)


Oregon Health & Science University, Otolaryngology (2005)     


University of Iowa Hospitals and Clinics Program, Otolaryngology - Neurotology (2008)
  • ​R01 from the NIH/NIDCD to support research program
  • Outstanding Teacher of the Year Award, University of Colorado, Department of Otolaryngology (2017)
  • University of Wisconsin Division of Otolaryngology, Faculty of the Year (2013)
  • American Otological Society Research Fellowship
  • American Academy of Otolaryngology / Head and Neck Surgery Resident Research Award

​Dr. Gubbels’ lab is interested in using a variety of stem cell types to model the development, disease and regeneration of inner ear hair and supporting cells in vitro. His research focuses on defining a method to reliably direct the differentiation of human pluripotent stem cells into auditory hair cells and other inner ear cell types. In addition, he seeks to evaluate the ability of these cells to integrate into the appropriate areas of the inner ear upon transplantation by using a novel, developmental in vivo model system. In addition, his research uses a number of transgenic mouse models to evaluate the persistence of a population of stem cell-like cells in the adult mammalian cochlea. 

In addition to his basic and translational research interests, Dr. Gubbels is involved in a variety of clinical research projects. Areas of particular interest are in imaging of cochlear implants, hearing preservation in cochlear implantation and skull base surgery, and cochlear implant indications.


  • ​​Anna Dondzillo, PhD, University of Colorado, Department of Otolaryngology
  • Richard JH Smith, MD, University of Iowa, Department of Otolaryngology​

  • ​American College of Surgeons (ACS) - Fellow, Member
  • American Academy of Otolaryngology / Head and Neck Surgery (AAO-HNSF) - Member
  • Triological Society (TRIO) - Active Candidate for Fellowship
  • Association for Research in Otolaryngology (ARO) - Member
  • American Auditory Society (AAS) - Member
  • American Cochlear Implant Alliance - Member
  • American Neurotology Society (ANS) - Fellow, Member
  • American Medical Association (AMA) - Member