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Department of Orthopedics

Department of Orthopedics
 

Payne Regenerative Orthopedics Laboratory

University of Colorado Department of Orthopedics


Research taking place in the Regenerative Orthopedics Laboratory focuses on harnessing the regenerative potential of stem cells for bone and articular cartilage tissue engineering. We are particularly interested in optimizing and controlling the osteogenic and chondrogenic differentiation of mesenchymal stem cells (MSCs) and induced pluripotent stem cells (iPSCs) by using different growth factors, scaffolds and physicochemical cues. Our long-term goal is to translate these research efforts into the clinic to enhance bone fracture repair, to improve spine fusion and for early treatment of articular cartilage defects. In the area of pediatric orthopedics, we have a collaborative research project on growth plate tissue engineering. ​​