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Working in the BSC Petri Dish Retinal Cups Retinal Cups Section 1 Rod Photoreceptors in Human iPS Cell  Derived 3D Retina
 

CellSight

Ocular Stem Cell and Regeneration Research Program


​​OUR VISION: TO BRING SIGHT BACK TO LIFE 

CellSight is in its essence a synergistic cross-disciplinary team of investigators pursuing cutting-edge research and working in a highly collaborative manner with basic researchers and clinicians with a common vision: to develop novel stem cell-based therapeutics to save and restore sight in patients with blinding diseases.

OUR MISSION: CATALIZING STEM CELL INNOVATIONS TO TREAT OCULAR DISEASES 

CellSight integrates several independent research groups that have come together as a unified team to find solutions to ocular diseases. In a concerted effort, the investigators at CellSight work with the clinicians at the Lions Eye Center and the Gates Center for Regenerative Medicine​​ with a goal of translating innovative treatments from the laboratory bench to the bed side.


OUR PARTNERS

Our ongoing collaborative work with investigators from the Gates Center for Regenerative Medicine​ and the Skaggs School of Pharmacy position us particularly well for succeeding in the discovery of new therapies for eye diseases and in translating them from the lab to the clinic. Investigators at the Skaggs School of Pharmacy contribute with their expertise in drug development and testing. The Gates Center, with the Gates Biomanufacturing Facility, brings in the expertise and capability to produce our stem cell- and drug- based discoveries at the scale and quality required to initiate clinical trials. ​


CELLSIGHT IN THE NEWS

Automatic and adaptive heterogeneous refractive index compensation for light-sheet microscopy

Optical tissue clearing has revolutionized researchers’ ability to perform fluorescent measurements of molecules, cells, and structures within intact tissue.

Dr. Natalia Vergara participates on the Third Annual Emerging Vision Scientists Day Events on Capitol Hill

Dr. Natalia Vergara participates on the Third Annual Emerging Vision Scientists Day Events on Capitol Hill.

Enabling quantitative screening in retinal organoids--3D automated reporter quantification technology

The advent of stem cell-derived retinal organoids has brought forth unprecedented opportunities for developmental and physiological studies, while presenting new therapeutic promise for retinal degenerative diseases.

A Vision for Helping those with Sight Problems

Canto-Soler joins Ophthalmology and Gates Center for Regenerative Medicine team to develop cell-based treatments

Combinatorial regulation of a Blimp1 (Prdm1) enhancer in the mouse retina

The mouse retina comprises seven major cell types that exist in differing proportions. They are generated from multipotent progenitors in a stochastic manner, such that the relative frequency of any given type generated changes over time.

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