Dr. Jamie Peters
Primary Appointment: Assistant Professor, Anesthesiology
- BS in Biology, Virginia Tech, Blacksburg, VA
- PhD in Neuroscience, Medical University of South Carolina, Charleston, SC
- Post-doc, Psychiatry, University of Puerto Rico School of Medicine, San Juan, Puerto Rico
- Post-doc, Anatomy & Neurosciences, VU University Medical Center, Amsterdam, The Netherlands
- Assistant Professor, Neuroscience, Medical University of South Carolina, Charleston, SC
Mail Stop B112
12700 E. 19th Avenue, room P15-7490D
Aurora, Colorado 80045
Telephone: (303) 724-3933
Preclinical behavioral pharmacology using rodent self-administration models of addiction, optogenetic and chemogenetic dissection of neural circuit function, neural circuitry and mechanisms underlying extinction memory, and the intersection of aversion and reward in systems neuroscience.
Neural circuits that inhibit drug seeking. We use self-administration models in rats to probe the neural circuits responsible for initiating and stopping drug seeking. My research identified the infralimbic prefrontal cortex as a key brain region responsible for the inhibition of drug seeking after extinction. Extinction in these addiction models bears some similarity to cognitive behavioral therapy in humans. We are seeking new methods to artificially boost activity in extinction neural circuits to limit drug seeking.
Comparing neural circuits controlling cocaine versus heroin seeking. We have identified certain commonalities and differences in the neural circuits that inhibit drug seeking in cocaine- versus heroin-seeking rats. Understanding where and why these circuits diverge is critical to designing effective circuit-based treatment strategies for addiction.
The role of aversion in drug seeking. We are using pharmacological, optogenetic, chemogenetic, and behavioral approaches to induce aversion and/or alleviate aversion during drug withdrawal and examine the impact on drug-seeking behavior. Aversive states/memories can both drive and inhibit drug seeking depending on the approach, timing of intervention, and particular drug of abuse.
Click here for Dr. Jamie Peters' publications on NCBI