Q: Doesn't grapefruit inhibit p450?
A: I have heard that there is a compound in grapefruit that occupies the active site and inhibits its efficacy.
Q: How does aspirin prevent heart attacks?
What kind of drugs, if any, are stored indefinitely in the body?
A: Can you eventually reach the toxic level? I have heard of this phenomenon with chemicals like monomeric poly-acrylamide.
Q: What is the difference between Naproxen and Ibuprofen? And which is the best anti-inflammatory?
A: Rather than try to give you a quick answer, because this is a question on which a lot might ride, please look at Consumers Reports discussion of these two drugs: