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University of Colorado Cancer Center

University of Colorado Cancer Center, A National Cancer Institute-designated Comprehensive Cancer Center

Established in 1999, the University of Colorado Cancer Center's Lung Cancer SPORE is a National Cancer Institute-funded program that aims to fast-track basic research findings to cancer patients and people at risk for cancer. Located at the CU Cancer Center and the Medical University of South Carolina, the Lung Cancer SPORE is funded through 2013 on a five-year grant totaling $11.5 million.

Our goal is to bring new ideas from the laboratory to the clinic and from the clinic to the lab, that can improve survival and quality of life while reducing the number of people who get lung cancer and who die from the disease.

Research is focused on developing biomarkers that can help doctors detect lung cancer earlier, assign prognosis and predict which patients will best respond to new types of treatments.

Current Funding Period: 2008-2013

Principal investigator: Dr. Paul A. Bunn, Jr., MD.

Locations: University of Colorado Cancer Center and Medical University of South Carolina


  • Project 1: SEMA3F and ZEB1 in Lung Cancer: Therapy & Target Gene Discovery
  • Project 2: Growth Factor Inhibitors for Lung Cancer Therapy and Prevention
  • Project 3: Prostacyclin and Peroxisome Proliferator-Activated Receptor ƒ×ƒn in Lung Cancer
  • Project 4: The Biology of Pulmonary Premalignancy: Application to Risk Assessment and Chemoprevention
  • Shared Resources:

  • Tissue Biobanking & Processing
  • Clinical Investigations
  • Biostatistics & Bioinformatics
  • Administration