Bharadwaj, S., Hitchcock-DiGregori, S., Thorburn, A. and Prasad, G.L. (2004). “Amino terminus is essential for Tropomyosin functions: N-terminal modification disrupts stress fiber organization and abolishes anti-oncogenic effects of Tropomyosin-1.” J. Biol. Chem. 279, 14039-14048.
Thomas, L.R., Henson, A. Reed, J.C., Salsbury, F. R., and Thorburn, A. (2004). “Direct binding of FADD to the TRAIL receptor DR5 is regulated by the death effector domain of FADD.”J. Biol. Chem. In Press. doi: 10.1074/jbc.M401680200
Bender, L.M., Morgan, M.J., Thomas, L.R. Liu, Z-G., and Thorburn, A. (2005) “The adaptor protein TRADD activates distinct mechanisms of apoptosis from the nucleus and cytoplasm.” Cell Death & Differentiation. 12, 473-481.
Thorburn, J., Moore, F., Rao, A, Barclay, W., Thomas, L.R., Grant, K.W, Cramer, S.D. and Thorburn, A. (2005) “Selective inactivation of a FADD-dependent apoptosis and autophagy pathway in immortal epithelial cells.” Mol. Biol. Of the Cell. 16, 1189-1199.
Bender, L.M. and Thorburn, A. (2005) “Death Domain interactions in Death Receptor Signaling” (2005) Journal of Biological Sciences. 5, 33-37.
Iordanov MS, Kirsch JD, Ryabinina OP, Wong J, Spitz PN, Korcheva VB, Thorburn A, Magun BE. (2005) “Recruitment of TRADD, FADD, and caspase 8 to double-stranded RNA-triggered death inducing signaling complexes (dsRNA-DISCs)”. Apoptosis 10, 167-176.
Liu, T.-F., Hall, P.D., Cohen, K.A., Willingham, M.C., Cai, J., Thorburn, A., and Frankel, A.E. (2005). “Interstitial diphtheria toxin-epidermal growth factor fusion protein therapy produces regressions of human glioblastoma multiforme tumors in athymic nude mice.” Clinical Cancer Research. 11, 329-334.
Thorburn, A. (2005) “Apoptosis induction by tumor targeted toxins.” In Application of Apoptosis to Cancer Treatment, ed. M. Sluyser. Springer Science and Business media.
Alappat, E.C., Feig. C., Volkland, J., Boterinas, B., Samuels, M., Murmann, A.E., Thorburn, A., Kidd, V.J., Slaughter, C.A., Osborne, S.L., Winoto, A., Tang, W., Peter, M.E., (2005). “Phosphorylation of FADD at Serine 194 by CKIa regulates its nonapoptotic activities.” Molecular Cell 19, 321-232.
Thomas, L.R., Bender, L.M., Morgan, M.J., and Thorburn, A. (2006) “Extensive regions of the FADD death domain are required for binding to the TRAIL receptor DR5.” Cell Death & Differentiation 13, 160-162.
Thorburn, A. and Frankel, A.E. (2006) “Apoptosis and anthracycline cardiotoxicity” Molecular Cancer Therapeutics. 5, 197-199.
Zhao, W., Kridel, S., Thorburn, A., Kooshli, M., Little, J., Hebbar, S., and Robbins, M. (2006) Fatty acid synthase: a novel target for antiglioma therapy. Br. Journal of Cancer 95, 869-878.
Hippert, M.M., O’Toole, P.S. and Thorburn, A. (2006) “Autophagy in cancer: good bad or both?” Cancer Research 66, 9349-9351.
Behbakht, K., Qamar, L., Aldridge, C., Coletta, R.O., Davidson, S.A., Thorburn, A., and Ford, H.L. (2007) “Six1 over-expression in ovarian carcinoma causes resistance to TRAIL-mediated apoptosis and is associated with poor survival.” Cancer Research 67, 3036-3042.
Thorburn, A. (2007) “Tumor Necrosis factor-related Apoptosis Inducing Ligand (TRAIL) Pathway Signaling.” Journal of Thoracic Oncology 2, 461-465.
Lyone, T.R., Thorburn, J., Ryan, P.W. Thorburn, A., Anderson, S.M. and Kassenbrock, C.K. (2007) “Regulation of the pro-apoptotic scaffolding protein POSH by Akt.” Journal of Biological Chemistry, 282, 21987-21997.
Bin, L., Thorburn, J, Thomas, L.R. Clark, P.E., Humphreys R., and Thorburn, A. (2007) “Tumor-derived mutations in the TRAIL receptor DR5 inhibit TRAIL signaling through the DR4 receptor by competing for ligand binding.” Journal of Biological Chemistry, In Press.
Horita, H., Frankel, A.E. and Thorburn, A. (2007) “Acute Myeloid Leukemia-targeted toxins kill tumor cells by cell type-specific mechanisms and synergize with TRAIL to allow manipulation of the extent and mechanism of tumor cell death. Leukemia. In Press.
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