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Clinical Trials

Volunteer to Be Part of a Research Study

Page through all School of Medicine clinical and research trials below. There are two categories:

  • Detailed Trial Descriptions, submitted by researchers, includes trial specifics and contact information.

  • Additional Clinical Trials, which include basic study details. To contact the researcher either Google the PI (primary investigator) name or use our campus directory.

If you are a researcher seeking volunteers and your study is not posted, please
submit your Web ad here.
  

Detailed Trial Descriptions

 Results From Research and Clinical Trials : Selected site
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COMIRB Approved Advertisement TitleStudy GoalsEligibility CriteriaDate PostedCategory
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Type 2 Diabetes and Exercise Research Study
Perceived exertion during exercise
Person 50-70 with or without Type 2 diabetes who exercise vigorously less than one hour per week and have normal blood pressure.  You should have a BMI between 25-35 and have not smoked for a least one year.
9/27/2016 
Participants Ages 12-15 years old Needed for Research Study
To learn about how children with absence epilepsy compare to healthy children in areas such as behavior, neuropsychological skills and quality of life.
Healthy hispanic individuals who are 12-15 years; No history of seizures, seizure like episodes, neurological diseases or a loss of consciousness greater than 5 minutes in their immediate family
9/27/2016 
MRI and Questionnaire Research Study for Patients with MS Taking Tysabri and Healthy Controls
This research study plans to learn more about the differences in brain scans and self-reported quality of life between MS patients taking natalizumab (Tysabri) and individuals without MS.
A relapsing Multiple Sclerosis patient 18-55 years old who has been taking Tysabri (natalizumab) for at least 2 years

OR

A healthy individual 18-55 years old without Multiple Sclerosis or other neurological conditions
9/27/2016 
Participants Needed for an Exercise Study for People with Multiple Sclerosis
Researchers from the Neurophysiology of Movement Laboratory on the University of Colorado Boulder campus and the Multiple Sclerosis Center on the University of Colorado Anschutz Medical Campus are conducting a study to investigate the capacity of neuromuscular electrical stimulation to improve walking in persons with multiple sclerosis.
-Between 18 to 55 years of age -Have clinically confirmed diagnosis of MS -Are able to talk but have some difficulty walking
9/27/2016 
Help test a mobile app for postpartum moms
This research study will test a mobile application to learn more about how to best deliver information about diet and physical activity for postpartum women at elevated risk for diabetes and heart disease.
You may qualify for this study if you:  Are between 18-45 years old  Are in your third trimester of pregnancy or have given birth in the last 24 weeks  Have a postpartum BMI: 25-45 kg/m2  Have access to and be willing to use a wi-fi enabled iPhone or an iPod  Have a history of one or more of the following complications in your most recent pregnancy: o Gestational diabetes mellitus o Preeclampsia o Gestational hypertension o Pre-term delivery (32-37) weeks o Small for gestational age (
9/27/2016 
Healthy Individuals needed for Genetic Study of Granulomatous Interstitial Lung Disease.
To investigate genetic factors associated with the disease sarcoidosis.
Must be 18 years or older with no history of chronic lung disease (including asthma) or connective tissue/rheumatological disease. Participants must complete a questionnaire and have a small blood draw.
9/27/2016Respiratory Tract (Lung and Bronchial) Diseases
We are seeking physically active women and men for a research study on PTH and Calcium Responses to Exercise (PACE) in Older Adults
To determine 1) if sweating rate during exercise affects the decrease in blood calcium level, and 2) if this causes an increase in a hormone called parathyroid hormone or PTH that causes bone to release calcium.
 A 60-80-year-old woman or man in generally good health  Often walk for exercise and can walk for an hour at a time  Not taking osteoporosis medication  No history of Diabetes or Cardiovascular Disease
9/27/2016--Select a Category--
Social Networks of Abused Prescription Pills in Youth (SNAPPY) Research Study
The purpose of this research study is to learn more about the misuse of prescription pills and the risk for injection drug use.
You may be selected to participate in the study if you are: • Between the ages of 15 and 24 • Willing to provide information about people in your life and things you do with them • Currently using prescription opioids without a doctor’s prescription or in ways other than what was prescribed OR • Currently using heroin after a period of misusing prescription opioids
9/27/2016Substance Related Disorders
We are seeking physically active men for a research study on PTH and Calcium Responses to Exercise (PACE)
This study will determine how much calcium enters and leaves the blood during exercise.  The results of this study will help us find out why some adults who exercise a lot sometimes have low bone density
• Men in generally good health, aged 18-45 years • Regularly cycle for exercise and can ride for an hour at a vigorous intensity • Not taking medication for osteoporosis • No history of asthma
9/27/2016Muscle, Bone, and Cartilage Diseases
Women with Obesity Needed!
For brain imaging research study on how the brain works with we taste sweets. Your participation could help us to develop treatments and preventive measures for anorexia nervosa and obesity
Females 18 to 25 years old who are right-handed, currently overweight, have a body mass index (BMI) over 30, and no permanent implants or braces
9/27/2016Behaviors and Mental Disorders
A Study to Evaluate Dolutegravir plus Lamivudine Dual Therapy for the Treatment of Naive HIV-1-Infected Participants
The main purpose of this study is to evaluate how well a two-drug combination of study drugs (dolutegravir plus lamivudine) will suppress HIV at 24 weeks after starting treatment. The study will also look at the safety and tolerability of this study drug combination, and factors that may affect how well it works in different individuals.
-HIV-1 infected men and women at least 18 years of age -Have not taken HIV medications (except for successful prevention of HIV infection) -No evidence of resistance to the type of anti-HIV drugs being used in the study -Have blood HIV level (viral load) of at least 1000 copies/mL but less than 500,000 copies/mL -No active Hepatitis B infection
9/27/2016Viral Diseases
Participants needed for a Balance and Fall-Risk Research Study for People with Multiple Sclerosis
This study involves balance and head movement testing aimed at predicting risk of falls
Are between the ages of 30 and 60 years
• have MS
• are able to turn your head at least 30 degrees to the left,
• have not experienced a fall in the last 3 months
9/27/2016Nervous System Diseases
Volunteers Needed for a Research Study about Rheumatoid Arthritis
The purpose of this study is to learn more about how rheumatoid arthritis develops in women by studying women who do not have rheumatoid arthritis. Your participation in this study will help us determine if certain hormone or environmental factors affect the chances of developing protein markers associated with rheumatoid arthritis.
• You are a woman at least 18 years old • You do NOT have rheumatoid arthritis (RA)
9/27/2016--Select a Category--
Do you like food?
Participants needed for a study on foods Participants in this study will: - Rate a series of food pictures - Watch pictures of food during fMRI recording, to measure brain responses to the pictures - Complete an fMRI task with images shown briefly before food pictures. - May also eat a buffet-style breakfast and lunch. - Be compensated for their time (between 2-6 hours)
- Adults between 15-65 years old - BMI > 25
9/27/2016Nutritional and Metabolic Diseases
HEALTHY WOMEN NEEDED
To understand reproduction hormones and fertility potential. To understand how weight affects reproductive health and fertility potential
Be a healthy women age 21-39 with BMI between 18.5 and 24.9 or greater than 30  Have regular menstrual cycles (25-40 days)  Not currently using hormones (like birth control medication)  Be willing to have frequent blood samples drawn
9/27/2016--Select a Category--
Volunteers Needed for a Research Study about Rheumatoid Arthritis
The purpose of this study is to learn more about how rheumatoid arthritis develops by studying patients with very early disease.
You may be able to participate in the study if: You are at least 18 years old You have rheumatoid arthritis that was diagnosed within the past year You have not been treated with any rheumatoid arthritis medications except prednisone
9/27/2016Immune System Diseases
JUST DIAGNOSED WITH SHINGLES?
This study will look at the body's immune response (how the body fights infection) to the onset of shingles. 1-2 study visits for blood draws, over the course of 3 months.
18+ years of age; NO PRIOR HISTORY of shingles; have NEVER received the shingles vaccine; have DEVELOPED SHINGLES within the last 10 days.
9/26/2016 
protein and infant growth: Do you have a child younger than 6 months
Participants in this research study on protein from complementary foods (meat or dairy) and infant growth, will learn how protein consumption affects your child’s growth, fat gain, and gut health from 6 to 12 months of age.  
To qualify, you child needs to be: 1. Formula fed, or not on breast-milk longer than 1 month. 2. Younger than 6 months. 3. Generally healthy. You will receive commercially available complementary foods for 7 months, Receive infant formula at no cost for 7 months, You will know your child's body fat and fat free mass and blood lipid level.
9/26/2016 
HAVE YOU OR YOUR CHILD BEEN DIAGNOSED WITH ASTHMA?
We are looking for volunteers to participate in an N.I.H. funded research study.
Children 12 years of age and older and non-smoking Adults who have mild to moderate asthma who are not currently taking inhaled steroid medication
9/26/2016 
Do You or Someone You Know Suffer From Relapse Remitting Multiple Sclerosis (RRMS)?
The University of Colorado Denver is conducting a clinical trial to evaluate the effectiveness, safety and tolerability of two doses of oral administration of laquinimod in subjects with Relapse Remitting Multiple Sclerosis (RRMS). Patients that suffer from RRMS may experience a gradual increase of their disability over time. The purpose of this study is to find out whether laquinimod is safe and effective in slowing the rate of disability progression.
-Between the ages of 18 and 55 -Have clinically confirmed diagnosis of Multiple Sclerosis (MS) with relapse onset disease or relapsing-remitting disease course -Have had at least one documented relapse within 12 months prior to starting this study -Have not been treated with Natalizumab (Tysabri) or Rituximab 2 years prior to starting this study
9/26/2016 
Sedentary Behavior Research Study
This research study plans to learn more about how the time we spend seated affects your health
Healthy male and female Age: 19-45 With BMI: 27-33 you may check this at: http://nhlbisupport.com/bmi/ Be seated more than 6hr/d Be physically active on less than 3-4 days/wk
9/26/2016 
Healthy Minority Volunteers Needed
This study plans to learn more about how tenofovir and emtricitabine (Truvada) build up in cells in blood and hair. Participation will include two 12 week dosing periods separated by a 12 week washout period (total duration is 36 weeks). Eligible participants will be given the supply of medications for the study.
Documented negative testing for HIV and hepatitis B Not at risk for HIV Study population balanced by Caucasian, African-American, Hispanic race. African American and Hispanic participants are currently needed. Age 18-50 years Able to meet study personnel on Anschutz Medical Campus for directly observed dosing with study medication, or by audio-visual communication with a mobile cellular device when off Campus
9/26/2016 
Participate in a research study about body image dissatisfaction and psychosocial distress among breast cancer patients
The purpose of this research study is to 1) determine the feasibility and impact of a 2 day body image workshop on breast cancer patients’ body image dissatisfaction, depression, and quality of life and 2) understand the relationships between body image, quality of life, and depression among patients with breast cancer.
Participants must be: 1) between the ages of 18-65, 2) histological or cytological confirmation of breast cancer (any clinical stage is allowed); 3) within 6 months of completion of surgery or final chemotherapy/radiation treatment for breast cancer, 4) experiencing concerns specific to body image.
9/26/2016Cancers and Other Neoplasms
Exercise for Healthy Aging in HIV
Determine the best “dose” of exercise in people aging with HIV, and whether or not the dose differs from people without HIV.
Men and women aged 50-70, on antiretroviral therapy for a minimum of 2 years with no detectable viral load, CD4 count >200; no active hepatitis C or hepatitis B; no major health problems that would interfere with the ability to exercise; if diabetic, must be well-controlled on oral medications (no insulin); body mass index between 20 and 40; no current/chronic infections besides HIV.
9/26/2016--Select a Category--
Would you like to follow your baby's brain development? Study of Pre and Postnatal Infant Brain Growth and Development
will examine brain development during and after pregnancy, investigating different aspects of mother and infant nutritional health on your infant’s brain growth and cognitive development.  
As an expectant mother you can participate if you are less than 22 weeks pregnant; or if your healthy newborn infant is between 3 and 15 months of age.
9/26/2016Urinary Tract, Sexual Organs, and Pregnancy Conditions
Adults (18-55) and Children (8-14) with Asthma
This research study is being done to find the amount of cockroach extract that we need to put in the nose to cause nasal symptoms.  
-Be 18 to 55 or 8 to 14 years old -Have a history of asthma
9/26/2016Respiratory Tract (Lung and Bronchial) Diseases
Are you pregnant and do you have lupus, rheumatoid arthritis or type 1 diabetes?
We need your help to study possible causes of these autoimmune disorders.  Your baby’s umbilical cord can help us!  Qualifications include:
Adult (18 and older) pregnant women with SLE, type 1 diabetes, or RA Any race and ethnicity.
9/26/2016Immune System Diseases
RSV Vaccine Study
We are looking for volunteers to participate in a research study to test a vaccine to prevent Respiratory Syncytial Virus (RSV) illness in infants and children. Your child can participate if he/she has a healthy immune system and has never had an infection or illness caused by RSV.
Baby has never had RSV
9/26/2016--Select a Category--
Diabetic Male and Female Volunteers Needed for Exercise Research Study
Evaluate exercise function during single leg calf exercise in people with or without type 2 diabetes
Healthy Adults 30-70 with Type 2 diabetes but not using insulin. Must be a non-smoker who exercise no more than one time per week and have a BMI of 25-40
9/23/2016 
Persons with active, moderate to severe ulcerative colitis needed
This study is being conducted to investigate the efficacy of methotrexate in treating ulcerative colitis in patients that have active, moderate to severe colitis and have failed other types of therapies.
Inclusion: Ages 18-70 Ulcerative colitis has been diagnoses by routine criteria At least one of the following applies: steroid dependent failed 5-ASA (mesalamine) therapy, such as Asacol Failed/lost response to infliximab (Remicade) Intolerant/unresponsive to azathioprine (Imuran) or 6-MP (purinethol) therapy Exclusion (partial): Existing pregnancy, lactation, or planned pregnancy (men and women)
9/23/2016 

​Additional Clinical Trails

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RANDOMIZED PHASE III COMPARISON OF STANDARD DOSE (60 GY) VS HIGH DOSE (74 GY) CONFORMAL RADIOTHERAPY WITH CONCURRENT AND CONSOLIDATION CARBOPLATIN/PACLITAXEL +/- CETUXIMAB IN PATIENTS WITH STAGE IIIA/IIIB NON SMALL CELL LUNG CANCER
Kavanagh, Brian D07-0851
NEW TRENDS IN HIV-RELATED RISKY PATTERNS OF INJECTING DRUG USE AND DRUGS DISTRIBUTION IN FOUR EURASIAN COUNTRIES WITH SUBSTANTIAL PRESENCE OF ATDS
Booth, Robert E08-1117
Helping Ourselves, Helping Others: The Young Womens' Breast Cancer Study
Borges, Virginia F. M.D.08-1222
S0931, "EVEREST: EVErolimus for Renal Cancer Ensuing Surgical Therapy, a Phase III Study"
Lam, Elaine Tat M.D.11-0545
GOG 9923 - A PHASE I STUDY OF INTRAVENOUS CARBOPLATIN/PACLITAXEL OR INTRAVENOUS AND INTRAPERITONEAL PACLITAXEL/CISPLATIN IN COMBINATION WITH CONTINUOUS OR INTERMITTENT / /CTEP SUPPLIED AGENT ABT-888 (NSC #737664) AND CTEP-SUPPLIED AGENT BEVACIZUMAB (NSC #704865) IN NEWLY DIAGNOSED PATIENTS WITH PREVIOUSLY UNTREATED EPITHELIAL OVARIAN, FALLOPIAN TUBE OR PRIMARY PERITONEAL CANCER
Guntupalli, Saketh Ram11-0636
A Phase II Study of the Aurora and Angiogenic Kinase Inhibitor ENMD-2076 in Previously Treated Locally Advanced and Metastatic Triple-Negative Breast Cancer
Diamond, Jennifer R M.D.11-0684
Identifying Unique Risks to Pregnancy In Perinatally Infected HIV Positive Women
Weinberg, Adriana11-1653
Oncofertility Patient Registry
Kondapalli, Laxmi A12-0389
An International Phase 3, Randomized Trial of Autologous Dendritic Cell Immunotherapy (AGS-003) Plus Standard Treatment of Advanced Renal Cell Carcinoma (ADAPT)
Lam, Elaine Tat M.D.13-1546
A phase II study of ponatinib in cohorts of patients with lung cancer preselected using different candidate predictive biomarkers.
Camidge, David Ross MD, PhD13-2002
A Phase 2B Randomized, Controlled, Multicenter, Open-Label Study of the Efficacy and Immune Response of GVAX Pancreas Vaccine (with Cyclophosphamide) and CRS-207 Compared to Chemotherapy or to CRS-207 Alone in Adults with Previously Treated Metastatic Pancreatic Adenocarcinoma
Weekes, Colin Dexter13-3144
Vascular mechanisms for the effects of loss of ovarian hormone function on cognition in women
Hildreth, Kerry L. MD14-0193
A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study Assessing the Effect of Gelesis100 on Body Weight in Overweight and Obese Subjects with and without Type 2 Diabetes. Sponsor Protocol No. G-04. WIRB Protocol No. 20150046
Hill, James O PhD14-0383
Reclaim Deep Brain Stimulation Therapy for Obsessive-Compulsive Disorder
Abosch, Aviva M.D.14-0554
A Phase I Trial of Inhaled Iloprost for the Prevention of Lung Cancer in Former Smokers
Miller, James York E M.D.14-1247
LIBERTY 360: Prospective, Observational, Multi-Center Clinical Study to Evaluate Acute & Long Term Clinical & Economic Outfomes of Endovascular Device Intervention in Patients with Distal Outflow Peripheral Arterial Disease (PAD)
Armstrong, Ehrin14-1522
Multicenter, open-label, randomized, controlled phase III clinical study of the efficacy and safety of photodynamic therapy using porfimer sodium for injection as treatment for unresectable advanced perihilar cholangiocarcinoma Sponsor Protocol No. PIN-PHO1201 WIRB Protocol No. 20140456
Shah, Raj Jay M.D.14-1650
Functional Avoidance Radiation Therapy for Lung Cancer Patients
Vinogradskiy, Yevgeniy14-1856
Self-reported usage patterns of opioid analgesic medications after surgery
Bartels, Karsten14-1938
Pilot study of a surgery and chemotherapy-only approach in the upfront therapy of children with WNT positive standard risk medulloblastoma
Dorris, Kathleen McCarthy O'Toole14-2097
Analysis of cataract surgery outcomes performed at the Children's Hospital Colorado from January 2005 through October 2014
Singh, Jasleen14-2183
A PHASE 3B RANDOMIZED STUDY OF LENALIDOMIDE (CC-5013) PLUS RITUXIMAB MAINTENANCE THERAPY FOLLOWED BY LENALIDOMIDE SINGLE-AGENT MAINTENACE VERSUS RITYUXIMAB MAINTENANCE IN SUBJECTS WITH RELAPSED/REFRACTORY FOLLICULAR, MARGINAL ZONE OR MANTLE CELL LYMPHOMA
Bowles, Daniel W14-2282
Protocol for the Evaluation of Dario™ BGMS Performance at Elevated Altitude. Sponsor Protocol No. CP-0003; WIRB Protocol No. 20142637
Garg, Satish K14-2330
Use of Ultrasonic Bone Scalpel in Adolescent Idiopathic Scoliosis - Randomized Clinical Trial
Garg, Sumeet15-0036
A DOUBLE-BLIND, PLACEBO-CONTROLLED RANDOMIZED TRIAL TO STUDY THE VIASKIN MILK EFFICACY AND SAFETY FOR TREATING IgE-MEDIATED COW’S MILK ALLERGY IN CHILDREN (MILES STUDY) Sponsor Protocol No. MILES WIRB Protocol No. 20141789
Fleischer, David Mark M.D.15-0140
ABT-414 Alone or ABT-414 Plus Temozolomide versus Lomustine or Temozolomide for Recurrent Glioblastoma; a Randomized Phase II Study of the EORTC Brain Sponsor Protocol No. MI4-483 WIRB Protocol No. 20142384
Damek, Denise Marie15-0164
A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of Rivipansel (GMI-1070) in the Treatment of Vaso-Occlusive Crisis in Hospitalized Subjects with Sickle Cell Disease
Hassell, Kathryn L M.D.15-0391
Predicting the Safety and Effectiveness of Inferior Vena Cava Filters (PRESERVE) Sponsor Protocol No. G140045 P WIRB Protocol No. 20150996
Rochon, Paul J M.D.15-0537
Reproductive and Sexual Health Issues in Young Women with CF: A Patient Survey
Sagel, Scott D MD, PhD15-0575
In-Clinic Feasibility Study to Observe the Closed Loop System. Sponsor Protocol No. CEP273/Z25. WIRB Protocol No. 20130443
Slover, Robert H. M.D.15-0684


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