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Clinical Trials

Volunteer to Be Part of a Research Study


Page through all School of Medicine clinical and research trials below. There are two categories: 

  • Detailed Trial Descriptions, submitted by researchers, includes trial specifics and contact information.

  • Additional Clinical Trials, which include basic study details. To contact the researcher either Google the PI (primary investigator) name or use our campus directory.

If you are a researcher seeking volunteers and your study is not posted, please submit your Web ad here.  

Detailed Trial Descriptions

 Results From Research and Clinical Trials : Selected site
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COMIRB Approved Advertisement TitleStudy GoalsEligibility CriteriaDate Posted
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Investigations in Gestational Origins of Lifetime Development: Understanding health begins before birth. Are you in your first trimester of Pregnancy?
To learn more about how your metabolism is connected to your baby's growth and development
Healthy Women ages 18-35 who are 10-14 weeks pregnant with single baby.  Norm BMI or 30-38 who are willing to complete 5 visits during pregnancy and agreeable to an infant blood draw at birth and DXA postpartum.  Delivery must be at University of Colorado Hospital.  there is an option to take part in a 1 year follow-up which entails an additional 4 visits and another DXA at 1 year of life.
11/26/2014
We are Currently Enrolling People with Down syndrome for a study in Dr. Pelak's Brain and Vision Research lab at the University of Colorado Anschutz Medical Campus.
To examine visual brain function in people with mild memory impairments to detect early signs of Alzheimer's Disease.​
Persons 19-30 who have Down Syndrome
11/26/2014
EMERALD STUDY: Effects of MEtformin on CardiovasculaR function in AdoLescents with Type 1 Diabetes
​To determine the effects of Metformin on Cardiovascular Function in Adolescents with Type 1 Diabetes.
Persons 12-21 who have Type 1 Diabetes, non-smoker, able to ride a stationary bike   You must be willing to take metformin or placebo (sugar pill) for 3 months.   Other exclusions apply, please contract study for more information
11/26/2014
Children's Hospital, department of Pediatric Neurology is conducting a research study
Evaluating the effects of a single treatment of injected BOTOX® (Botulinum Toxin Type A) for chronic migraine(s) in adolescents.
Adolescents 12-17 who have no serious medical conditions but have at least 15 headaches a month for the last 6 months. You not have any previous BOTX treatments or are not currently using any prophylactic medicine.
11/26/2014
Non-Alcoholic Fatty Liver Disease and Obstructive Sleep Apnea: Mechanistic Links between Hypoxemia and Liver Injury
To learn if obstructive sleep apnea and low oxygen levels have a role in developing Non-Alcoholic Fatty Liver Disease (NAFLD).​​​
Children 10-17 who have a normal weight and no serious medical problems
11/26/2014
Volunteers are invited for a research studying looking at pain in knee osteoarthritis
To better understand the complex experience of pain for people with knee osteoarthritis
Persons 50 or older who have been diagnosed with knee osteoarthritis
11/26/2014
Exercise and Cancer Prevention Research Study
The goal of this study is to better understand the biological mechanisms associated with exercise and reduced risk for breast cancer.
You must be a female between the ages of 30-45 to participate in this study. You must be planning to live in the Denver metropolitan area for the next 10 consecutive months. You should not be a regular exerciser because this study is for people who do not exercise right now; however, you should be willing to participate in an exercise program 4 times per week for 16-weeks.
11/26/2014
Are you interested in a supervised exercise intervention?
Volunteers are needed for a research study to examine the effects of exercise on food intake and appetite regulation.
- 21-45 years old - Non- smoker - Non- Diabetic - Exercise no more than 1 time a week - Maintained your current weight for last 6 months - Have a body mass index (BMI) of 27-35 (check it out at http://nhlbisupport.com/bmi/)
11/26/2014
Study of Mood Disorder in Preschool Children
We are doing a research study to better understand what mood disorders look like in preschool children.
We are looking for volunteers who:   *    Are parents of children between the ages of 4 and 6 years 0 months.  *    Are in one of three groups:         1) Their child has no major mental health problems, and there is            no family history of major mood or psychotic disorders.          2) Their child has been diagnosed with a mood disorder, bipolar disorder, or              mood dysregulation disorder.  3) Their child has been diagnosed with attention deficit hyperactivity  disorder (ADHD).  Parents or guardians will be asked to:                *    Read and sign a consent form               *    Participate in interviews about their children. The  children will be asked to:    *    Participate in a story game    *    Take tests of verbal and nonverbal abilities   How much time will this take? The visit for the child will last from 1 to 2 hours.  The visit for the parents will last 3 to 5 hours.
11/26/2014
MRI and Questionnaire Research Study for Patients with MS Taking Tysabri and Healthy Controls
This research study plans to learn more about the differences in brain scans and self-reported quality of life between MS patients taking natalizumab (Tysabri) and individuals without MS.
-A relapsing Multiple Sclerosis patient 18-55 years old who has been taking Tysabri (natalizumab) for at least 2 years OR -A healthy individual 18-55 years old without Multiple Sclerosis or other neurological conditions
11/26/2014
Understanding how Tysabri and Gilenya Influence the Quality of your Daily Life with Multiple Sclerosis
The purpose of this research study is to compare two medications, Tysabri and Gilenya, used in the treatment of multiple sclerosis (MS), through a few self reported patient surveys. We will ask you to complete online surveys about overall health-related quality of life, disability, fatigue, cognition and productivity. We will also want to review your medical records to understand your MS history with your permission. This study will help us understand how these drugs are impacting each aspect of your daily lives.
-Between ages 16 and 65 -Scheduled to start natalizumab or fingolimod for the first time to treat your MS
11/26/2014
Living with MS?
To evaluate the safety of a new investigational drug that may help reduce relapses.
-Between the ages of 18 to 65 -Participants must have relapsing-remitting multiple sclerosis (RRMS)
11/26/2014
High Altitude Research Study
Subjects needed for a study on how high altitude affects cognitive performance
Male and Female subjects needed that are: • Between the ages of 18-45 years old and exercise regularly • Healthy: non smokers and not on medications • Willing to stay below 7,000 ft for 3 weeks prior to altitude chamber day
11/26/2014
Brown Adipose Tissue and Estrogen (BATE Study)
To investigate whether estrogen influences the activity of brown adipose tissue.
Healthy non-smoking women 20-40 who have regular menstrual cycles and are not on hormonal contraceptives and exercise more than once per week
11/25/2014
Type 2 Diabetes and Exercise Research Study
Perceived exertion during exercise
Person 50-70 with or without Type 2 diabetes who exercise vigorously less than one hour per week and have normal blood pressure.  You should have a BMI between 25-35 and have not smoked for a least one year.
11/25/2014
Is your child 6-18 years old and interested in participating in a research study?
To study the effects of polycystic kidney disease (PKD) on blood vessel function
Children 6-22 free from kidney disease and other chronic diseases
11/25/2014
Evaluation of Glucose Sensor and Insulin Infusion Set Failures: Lipohypertrophy Study
This study is looking at evaluating Insulin Pump Infusion sites and Continuous Glucose Monitoring sites in tissue with Lipohypertrophy. We will also be looking at using the sites for a longer duration.
Lipohypertrophy site of 3 cm or greater in diameter Ages 12-45 inclusive A1C Value of < 10% Insulin pump use of at least 3 month duration Pump use with Medtronic, Animas or T-slim Willing to wear two CGM's during the 4 weeks of the study
11/25/2014
Participants Ages 12-15 years old Needed for Research Study
To learn about how children with absence epilepsy compare to healthy children in areas such as behavior, neuropsychological skills and quality of life.
Healthy hispanic individuals who are 12-15 years; No history of seizures, seizure like episodes, neurological diseases or a loss of consciousness greater than 5 minutes in their immediate family
11/25/2014
University of Colorado is looking for Pregnant Women to participate in a text messaging and Facebook research study.
The University of Colorado is doing a research study to learn how best to deliver text messages and social media that encourage pregnant women to breastfeed.
Females 18-40 who can speak and write in English or Spanish  You must be at least 36 weeks pregnant and have access to a mobile device that can receive text messages and has access to the Internet (smart phone).
11/25/2014
Healthy Hispanic Female Adolescents Needed!!!
For brain imaging research study on how the brain works with we taste sweets or receive money. Your participation could help us to develop treatments and preventive measures for anorexia nervosa and obesity.
Healthy females 11 to 21 who are right-handed, free of medication with no serious medical conditions or permanent metal implants or braces/retainers and are at a healthy body weight.
11/25/2014
Participants Needed for an Exercise Study for People with Multiple Sclerosis
Researchers from the Neurophysiology of Movement Laboratory on the University of Colorado Boulder campus and the Multiple Sclerosis Center on the University of Colorado Anschutz Medical Campus are conducting a study to investigate the capacity of neuromuscular electrical stimulation to improve walking in persons with multiple sclerosis.
-Between 18 to 55 years of age -Have clinically confirmed diagnosis of MS -Are able to talk but have some difficulty walking
11/25/2014
Are you stopping your birth control because you want to become pregnant?
To look at contraception rates after birth control discontinuation.
Women 18-35 who are planning to, or have recently stopped their birth control because they want to become pregnant.
11/24/2014
Healthy Postmenopausal Women needed to participate in a research study
To test whether estrogen has different effects on blood sugar early in menopause compared to many years after menopause​.​
Women 45-70 who have gone through menopause within the past 6 years or are more than 10 years past menopause, never used hormone therapy for more than 6 months and are willing to use estrogen patches for 1 week.  Must be a non-smoker and sedentary to moderately active.
11/24/2014
Type 1 Diabetes Research Study
To study the effects of a medication on metabolism and blood vessel function.
Persons 25-50 years old with or without type 1 diabetes with normal blood pressure and exercise vigorously no greater than 3 times per week.
11/24/2014
JUST DIAGNOSED WITH SHINGLES?
This study will look at the body's immune response (how the body fights infection) to the onset of shingles. 1-2 study visits for blood draws, over the course of 3 months.
18+ years of age; NO PRIOR HISTORY of shingles; have NEVER received the shingles vaccine; have DEVELOPED SHINGLES within the last 10 days.
11/24/2014
protein and infant growth: Do you have a child younger than 6 months
Participants in this research study on protein from complementary foods (meat or dairy) and infant growth, will learn how protein consumption affects your child’s growth, fat gain, and gut health from 6 to 12 months of age.  
To qualify, you child needs to be: 1. Formula fed, or not on breast-milk longer than 1 month. 2. Younger than 6 months. 3. Generally healthy. You will receive commercially available complementary foods for 7 months, Receive infant formula at no cost for 7 months, You will know your child's body fat and fat free mass and blood lipid level.
11/24/2014
Volunteers Needed: Thinking and Memory in Parkinson's Disease
This research study aims to better understand how changes in brain activity may be related to thinking problems in Parkinson's Disease and to determine whether, by stimulating certain areas, thinking and memory can be improved.
Person's with Parkinson's Disease with mild thinking and memory problems. Between 40-90 years old. No metal in your body. No implant. Not taking any medication to improve memory. Not taking stimulants or seizure medication.
11/24/2014
Research Participants Needed
We are looking for participants with diabetes to serve as a standard for comparison when describing physical function outcomes before and during prosthetic rehabilitation.
Inclusion Criteria: 1) 50-85 years of age. 2) Able to walk continuously without assistance (i.e., do not use a cane or walker) for 10 minutes and physically active (e.g., participate in recreational activities like walking, jogging, hiking). 3) Diagnosis of diabetes. 4) No other neurological, vascular or cardiac problems that limit function. 5) Body mass index
11/24/2014
HAVE YOU OR YOUR CHILD BEEN DIAGNOSED WITH ASTHMA?
We are looking for volunteers to participate in an N.I.H. funded research study.
Children 12 years of age and older and non-smoking Adults who have mild to moderate asthma who are not currently taking inhaled steroid medication
11/24/2014
Do You or Someone You Know Suffer From Relapse Remitting Multiple Sclerosis (RRMS)?
The University of Colorado Denver is conducting a clinical trial to evaluate the effectiveness, safety and tolerability of two doses of oral administration of laquinimod in subjects with Relapse Remitting Multiple Sclerosis (RRMS). Patients that suffer from RRMS may experience a gradual increase of their disability over time. The purpose of this study is to find out whether laquinimod is safe and effective in slowing the rate of disability progression.
-Between the ages of 18 and 55 -Have clinically confirmed diagnosis of Multiple Sclerosis (MS) with relapse onset disease or relapsing-remitting disease course -Have had at least one documented relapse within 12 months prior to starting this study -Have not been treated with Natalizumab (Tysabri) or Rituximab 2 years prior to starting this study
11/24/2014

​Additional Clinical Trails

 Results From Research : Selected site
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NSABP B-31 A RANDOMIZED TRIAL COMPARING THE SAFETY AND EFFICACY OF ADRIAMYCIN AND CYCLOPHOSPHAMIDE FOLLOWED BY TAXOL (AC-T) TO THAT OF ADRIAMYCIN AND CYCLOPHOSPHAMIDE FOLLOWED BY TAXOL PLUS HERCEPTIN (AC-T+H) IN NODE-POSITIVE BREAST CANCER PATIENTS WHO HAVE TUMORS THAT OVEREXPRESS HER2
Kounalakis, Nicole00-236
SWOG N9831 PHASE III TRIAL OF DOXORUBICIN AND CYCLOPHOSPHAMIDE (AC) FOLLOWED BY WEEKLY PACLITAXEL WITH OR WITHOUT TRASTUZUMAB AS ADJUVANT TREATMENT FOR WOMEN WITH HER-2 OVEREXPRESSING NODE POSITIVE OR HIGH-RISK NODE NEGATIVE BREAST CANCER
Elias, Anthony00-954
GOG#184 - A RANDOMIZED PHASE III STUDY OF TUMOR VOLUME DIRECTED PELVIC PLUS OR MINUS PARA-AORTIC IRRADIATION FOLLOWED BY CISPLATIN AND DOXORUBICIN OR CISPLATIN, DOXORUBICIN AND PACLITAXEL FOR ADVANCED ENDOMETRIAL CARCINOMA
Davidson, Susan01-101
A RANDOMIZED PHASE II CHEMOPREVENTION STUDY OF ILOPROST VERSUS PLACEBO IN PATIENTS AT HIGH RISK FOR LUNG CANCER
Keith, Robert01-279
A STUDY OF THE EFFECTIVENESS AND TOLERABILITY OF WEEKLY RIFAPENTINE/ISONIAZID FOR THREE MONTHS VERSUS DAILY ISONIAZID FOR NINE MONTHS FOR THE TREATMENT OF LATENT TUBERCULOSIS INFECTION [TBTC STUDY 26]
Gardner, Edward01-284
AUTOLOGOUS PAP-LOADED DENDRITIC CELL VACCINE (APC 8015, PROVENGE) IN PATIENTS WITH NON-METASTATIC PROSTATE CANCER WHO EXPERIENCE PSA ELEVATION FOLLOWING RADICAL PROSTATECTOMY IN RANDOMIZED, CONTROLLED, DOUBLE-BLIND TRIAL
Glode, Michael01-348
CHOLESTEROL AND ANTIOXIDANT TREATMENT IN PATIENTS WITH THE SMITH-LEMLI-OPITZ SYNDROME (SLOS)
Elias, Ellen01-410
A PHASE II STUDY OF ADJUVANT STI571 (GLEEVEC) THERAPY IN PATIENTS FOLLOWING COMPLETELY RESECTED HIGH-RISK PRIMARY GASTROINTESTINAL STROMAL TUMOR (GIST)
McCarter, Martin01-879
ANBL0032 PHASE III RANDOMIZED STUDY OF CHIMERIC ANTIBODY 14.18 (CH 14.18) IN HIGH RISK NEUROBLASTOMA FOLLOWING MYELOABLATIVE THERAPY AND AUTOLOGOUS STEM CELL RESCUE
Greffe, Brian01-932
RTOG 96-01 A PHASE III TRIAL OF RADIATION THERAPY WITH OR WITHOUT CASODEX IN PATIENTS WITH PSA ELEVATION FOLLOWING RADICAL PROSTATECTOMY FOR PT3NO CARCINOMA OF THE PROSTATE.
Rabinovitch, Rachel02-182
DIABETES PREVENTION PROGRAM OUTCOMES STUDY (DPPOS)
Dabelea, Dana02-498
ACOSOG Z9001: A PHASE III RANDOMIZED DOUBLE-BLIND STUDY OF ADJUVANT STI571 (GLEEVEC) VERSUS PLACEBO IN PATIENTS FOLLOWING THE RESECTION OF PRIMARY GASTROINTESTINAL STROMAL TUMOR (GIST)
McCarter, Martin02-607
EFFICACY OF AGGRESSIVE RENIN-ANGIOTENSIN-ALDOSTERONE AXIS BLOCKADE IN PREVENTING/SLOWING RENAL FUNCTION DECLINE IN ADPKD
Schrier, Robert02-744
RANDOMIZED EVALUATION OF RECURRENT STROKE COMPARING PFO CLOSURE TO ESTABLISHED CURRENT STANDARD OF CARE TREATMENT - RESPECT TRIAL
Anderson, Clark02-805
A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, MULTICENTER PHASE III STUDY COMPARING GW572016 AND LETROZOLE VERSUS LETROZOLE IN SUBJECTS WITH ESTROGEN/PROGESTERONE RECEPTOR-POSITIVE ADVANCED OR METASTATIC BREAST CANCER (EGF 30008).
Elias, Anthony03-1030
A CONTINUATION PROTOCOL FOR PI-88 IN PATIENTS WITH ADVANCED MALIGNANCIES
Eckhardt, Sue03-1250
AALL0031 A CHILDREN'S ONCOLOGY GROUP PILOT STUDY FOR THE TREATMENT OF VERY HIGH RISK ACUTE LYMPHOBLASTIC LEUKEMIA IN CHILDREN AND ADOLESCENTS
Giller, Roger03-239
IMPAACT P1026s: Pharmacokinetic Properties of Antiretroviral and Related Drugs During Pregnancy and Postpartum, Version 8.0
McFarland, Elizabeth03-546
PROSPECTIVE MULTICENTER EVALUATION OF THE DURATION OF THERAPY FOR THROMBOSIS IN CHILDREN
Wang, Michael03-585
TREATMENT OPTIONS FOR TYPE 2 DIABETES IN ADOLESCENTS AND YOUTH
Zeitler, Philip03-595
COLORECTAL CHEMOPREVENTION WITH CALCIUM AND VITAMIN D (THE VITAMIN D/CALCIUM POLYP PREVENTION STUDY)
Ahnen, Dennis03-993
CLINICAL CORRELATION AND COST ANALYSIS OF SICKLE CELL PATIENTS UNDERGOING CHRONIC ERYTHROCYTAPHERESES.
Hassell, Kathryn04-0005
A PHASE II MULTICENTER STUDY TO EVALUATE THE EFFICACY AND SAFETY OF 500 MG OF FULVESTRANT (FASLODEX) AS A FIRST LINE HORMONAL TREATMENT IN POSTMENOPAUSAL WOMEN WITH HORMONE RECEPTOR POSITIVE METASTATIC BREAST CANCER.
Borges, Virginia04-0303
Use Of 3,4-Diaminopyridine (3,4-Dap)In The Treatment Of Lambert-Eaton Syndrome (Lems)
Ringel, Steven04-0567
MET FULLY IMPLANTABLE OSSICULAR STIMULATOR
Jenkins, Herman04-0579
ACNS0331: A STUDY EVALUATING LIMITED TARGET VOLUME BOOST IRRADIATION AND REDUCED DOSE CRANIOSPINAL RADIOTHERAPY (18.00 GY) AND CHEMOTHERAPY IN CHILDREN WITH NEWLY DIAGNOSED STANDARD RISK MEDULLOBLASTOMA: A PHASE III DOUBLE RANDOMIZED TRIAL
Foreman, Nicholas04-0625
DOUBLE-BLIND TRIAL OF CHOLINE DURING PREGNANCY AND RISK FOR SCHIZOPHRENIA
Ross, Randal04-0678
A STUDY OF THE EVALVE CARDIOVASCULAR VALVE REPAIR SYSTEM (CVRS) ENDOVASCULAR VALVE EDGE-TO-EDGE REPAIR STUDY
Carroll, John04-0831
INSULIN RESISTANCE INTERVENTION AFTER STROKE (IRIS) TRIAL
Hughes, Richard04-0855
RTOG 0234 - A PHASE II RANDOMIZED TRIAL OF SURGERY FOLLOWED BY CHEMORADIOTHERAPY PLUS C225 (CETUXIMAB) FOR ADVANCED SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK
Rabinovitch, Rachel04-0991