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Clinical Trials

Volunteer to Be Part of a Research Study

Page through all School of Medicine clinical and research trials below. There are two categories:

  • Detailed Trial Descriptions, submitted by researchers, includes trial specifics and contact information.

  • Additional Clinical Trials, which include basic study details. To contact the researcher either Google the PI (primary investigator) name or use our campus directory.

If you are a researcher seeking volunteers and your study is not posted, please
submit your Web ad here.
  

Detailed Trial Descriptions

 Results From Research and Clinical Trials : Selected site
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COMIRB Approved Advertisement TitleStudy GoalsEligibility CriteriaDate PostedCategory
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SPIROMICS-Subpopulations and Intermediate Outcome Measures in COPD Study
To identify subpopulations of COPD patients in order to develop newer and more effective treatments and to clearly define measureable end points so that treatment effects may be accurately assessed in a shorter period of time.
Be willing to undergo study procedures Be between the age of 40 and 80 years old Have smoked fewer than one pack of cigarettes per day for one year OR have smoked more than one pack of cigarettes per day for 20 years
7/28/2016 
Healthy Female Adolescents Needed!!!
For brain imaging research study on how the brain works with we taste sweets or receive money. Your participation could help us to develop treatments and preventive measures for anorexia nervosa and obesity
Healthy females 11 to 21 who are right-handed, free of medication with no serious medical conditions, permanent metal implants or braces/retainers, and are at a healthy body weight.
7/28/2016 
A Study to Determine the Effectiveness of Seeing Dermatologist Online Compared to In-Person
The purpose of the study is to see whether seeing a dermatologist online is just as effective as seeing one in-person. Help us determine whether online-based model is cost-saving and more efficient compared to face-to-face visits!
In order to qualify for the study, you must be 18 years or older and have psoriasis. You must have access to the internet, and a digital camera or a mobile phone with a camera.
7/28/2016 
Do You or Someone You Care for Suffer from Troublesome Drooling?
A research study is being conducted to evaluate an investigational product for Sialorrhea (troublesome drooling).
You or your loved one may be eligible to participate if you meet the following criteria: 1. Have a diagnosis of Parkinson’s disease, adult cerebral palsy, ALS, stroke, traumatic brain injury, oral cancer, or side effects of medication, or any other condition that causes Sialorrhea or troublesome drooling 2. Have never received any type of treatment using Botulinum toxin type B 3. Have ability & availability to participate in a study for up to 1 year
7/28/2016 
Parkinson's Disease Research Study
clinical research study to look at the safety and effectiveness of an investigational medication, ADS-5102 (amantadine HCl) extended release capsules, for troublesome dyskinesia in subjects with Parkinson’s disease.
You may be eligible if you have Parkinson's Disease, currently take levodopa, and are experiencing troublesome dyskinesia (involuntary twisting and turning).
7/28/2016 
Type 2 Diabetes Medication Research Study
Studying the effects of sitagliptin (a diabetes medication) on exercise capacity in people with type 2 diabetes
-Be a man or woman between 22 and 70 years old -Be generally healthy, with type 2 diabetes -Be taking metformin only for your diabetes -Be a non-smoker -Have a Body Mass Index greater than 25.0
7/28/2016Nutritional and Metabolic Diseases
Research study to investigate how therapies work to reduce tension-type headache
To understand how massage or ultrasound therapies affect blood flow within myofascial trigger points that are related to chronic pain such as tension-type headache.
Persons aged 21-49 who experience chronic or episodic tension-type headache and are not currently receiving massage, ultrasound, trigger point injection, or needling therapies.
7/28/2016Muscle, Bone, and Cartilage Diseases
" EDEN "Estrogen, Diabetes and Endothelial Function
Study the effect of estrogen on blood vessels
CONTROL PARTICIPANT ELIGIBILITY · Age 18-45 · Premenopausal · Not using hormonal birth control currently or in the last 6 months (including oral contraceptives, contraceptive patch, Depo Provera, norplant, or IUD) · Not currently pregnant or planning to become pregnant in the next 3 months · No recent history of amenorrhea (no menstrual period for at least 3 months) during the last 6 months · Non-smoker · No antioxidant therapy (vitamin C or E or multivitamin) for at least 4 weeks prior to the first study visit   Normal thyroid function (can be treated)  T1D ELIGIBILITY  · Age 18-45 · Premenopausal · Have had type 1 diabetes for at least 5 years, were treated with insulin within a year of diagnosis, and are currently treated with insulin · Not using hormonal birth control currently or in the last 6 months (including oral contraceptives, contraceptive patch, Depo Provera, norplant, or  IUD) · Not currently pregnant or planning to become pregnant in the next 3 months · No recent history of amenorrhea (no menstrual period for at least 3 months) during the last 6months · Non-smoker · No antioxidant therapy (vitamin C or E or multivitamin) for at least 4 weeks prior to the first study visit  HbA1c < 9.5  Normal kidney function (urinary albumin excretion rate < 200 µg/min)         Normal thyroid function (can be treated)
7/28/2016Heart and Blood Diseases
Rhythmic Enhancement of Motor Performance
It is known that people with Parkinson's Disease are able to move better with music or rhythm. This research study plans to learn more about he areas of the brain that react to rhythm in people with Parkinson's Disease (PD) and healthy older adults.
Healthy male older controls aged 55-85.
7/28/2016Nervous System Diseases
Volunteers needed for functional MRI research study
Patients with schizophrenia are needed for a research study to learn more about how drugs used to treat illness symptoms affect weight gain and brain responses to food. We are also studying how exercise and diet affect these responses.
Diagnosis of schizophrenia/schizoaffective disorder; taking risperidone, olanzapine, or clozapine; capable of mild/moderate exercise; BMI less than 39; no heart problems or untreated high blood pressure; capable of MRI
7/28/2016Behaviors and Mental Disorders
Attention Teens! Are You Concerned About Gaining Too Much Weight During Pregnancy?
A research study at Children’s Hospital Colorado and Colorado State University seeks pregnant teenagers age 13-19y who may be at risk for gaining too much weight during pregnancy. Consider participating in this research study focused on testing a healthy pregnant weight gain program. The study involves 1 screening visit, 6 1-hour sessions during pregnancy or usual care, and follow-up visits within 3 months of having your baby. Eligible participants could be financially compensated up to $200-$250 for their time and inconvenience.
Female 13-19 years old Pregnant
7/28/2016--Select a Category--
We are looking for Healthy Women to participate in a research study on.....Females, Aging, Metabolism, and Exercise (FAME)
To examine the role that female sex hormones play in metabolism, energy expenditure, physical activity and chronic disease.
Healthy women 40-60 who have regular menstrual cycles and using no hormonal contraceptives
7/27/2016 
Do you have Diabetes?
To find the best combination drug treatment for type 2 diabetes
Persons who have had diabetes for less than 5 years and metformin is the only diabetes medication you are taking.
7/27/2016 
Type 1 Diabetes Research Study
To study the effects of an FDA-approved medication on metabolism and blood vessel function.
Person 25-50 with type 1 diabetes who exercise vigorously less than four times per week and have normal blood pressure
7/27/2016 
CHILDHOOD and ADOLESCENT MIGRAINE PREVENTION STUDY
to test two medicines for migraine prevention in children and teens. We want to see if amitriptyline and/or topiramate are better than placebo (sugar pill) in reducing headache frequency.
Children 8-17 who have migraine headaches
7/27/2016 
Just received VARIVAX, the chickenpox vaccine?
Research study looking at the immune response to chickenpox vaccine
Age 12 months to 50 years; able to enroll in study within 10 days of vaccination.
7/27/2016 
Healthy Hispanic Female Needed
For brain imaging research study on how the brain works with we taste sweets. Your participation could help us to develop treatments and preventive measures for anorexia nervosa and obesity
Healthy females 22 to 29 who are right-handed, free of medication with no serious medical conditions, permanent metal implants or braces/retainers, and are at a healthy body weight.
7/27/2016 
Looking for HIV-positive individuals to participate in a research study on Lipodystrophy Syndrome
We are conducting a study of the relationship of bacteria in the gut to HIV infection. We are interested in finding out whether people who have metabolic diseases such as lipodystrophy (loss of fat tissue) as complications of long term antiretroviral therapy have a different makeup of their gut bacteria. We are therefore seeking volunteers with HIV infection to participate in a study of bacteria in the stool.
-Non-obese HIV positive individuals who are 18-65 years old -Either not currently on antiretroviral therapy (ART naïve or off therapy for 6 months or greater) or on effective ART with documented suppression for 6 months or greater. -We are particularly interested in enrolling subjects with lipodystrophy, but would also like to enroll individuals without lipodystrophy as controls.
7/27/2016 
Looking for HIV-positive and HIV-negative men to participate in a research study on smoking and lung disease
We are conducting a study to look at lung complications and disease in HIV/AIDS.
-Between 30 and 70 years old -Both HIV-positive and HIV-negative individuals with and without chronic obstructive pulmonary disease (COPD) -If HIV-positive, on a stable three-drug ART regimen with undetectable viral load for past 6 months
7/27/2016 
GENETIC-AF
The GENETIC-AF is a trial that will investigate the safety and effectiveness of an investigational drug on the recurrence of symptomatic atrial fibrillation in people who have heart failure. The investigational drug will be studied versus an approved drug after patients receive an electrical cardioversion.
Adults who have symptomatic atrial fibrillation may be eligible.
7/27/2016Heart and Blood Diseases
Healthy Volunteers Needed
To examine the differences in two subtypes of Parkinson Disease compared to health controls. This study involves an MRI.
- Between the ages of 50-80 - No metal in your body - In general good health
7/27/2016Nervous System Diseases
WISH - Women, insulin and sex hormones. Premenopausal women with type 1 diabetes needed for a research study.
This study plans to learn more about the menstrual cycle in women with Type 1 diabetes compared to the women who do not have diabetes. In addition, this research study plans to learn about the relationship between reproductive hormone levels and early signs of heart disease and hardening of the arteries in women with Type 1diabetes.
Age 18-45 Premenopausal Not using hormonal birth control and planning to stay off of them for at least 3 months. No currently pregnant or planning to become pregnant in the next 3 months. No recent history of amenorrhea (no menstrual period for at least 3 months) during the last 6 months. Menstrual cycle between 25-35 days on average. Normal thyroid function (can be treated) Normal kidney function (urinary albumin excretion rate
7/27/2016Heart and Blood Diseases
Interested in Weight Loss?
We are researching an investigational device for weight loss in overweight or obese subjects. The device is taken in pill form in two doses daily and may help decrease food intake.
*Are between 22 – 65 years old *Are overweight or obese (a BMI ≥27 and ≤40) - Check your BMI at http://www.nhlbisupport.com/bmi/ *Are willing to participate in regular study visits at the Anschutz Medical Campus
7/27/2016Nutritional and Metabolic Diseases
Do you need Emergency Contraception? Sexually Active Women needed for research.
We are interested in evaluating the progesterone intrauterine device (IUD) as a method of emergency contraception to prevent pregnancy after unprotected sex.
You might be eligible if you: - Are 18-45 years of age - Have had unprotected sex in the last 5 days - Have had a lapse in your birth control such as a missed pill, forgot your shot, condom broke, etc.
7/27/2016Urinary Tract, Sexual Organs, and Pregnancy Conditions
Information for patients. Living with diabetes is complicated.
The FREEDOM-3S Study is a clinical research study that will involve approximately 126 patients in the United States. It will look at a potential new treatment option, the ITCA 650,for people with type 2 diabetes. The ITCA 650 is a small metal cylinder (about the size of a matchstick) that is placed under the skin of the abdomen (belly) to slowly release the study medication – exenatide. The FREEDOM-3S Study is looking at how safe and well tolerated two different doses of the ITCA 650 are in people with type 2 diabetes who are already taking liraglutide (also known as Victoza injections, and metformin.
You may be eligible to take part if you: • are 18–80 years of age • have been diagnosed with type 2 diabetes for at least 3 months • have been taking liraglutide (Victoza) injections and metformin every day for at least 3 months.
7/27/2016Gland and Hormone Related Diseases
Controlling blood glucose levels. Can be a real balancing act.
The EASE-3 clinical research study is a study in which doctors hope to learn: • Whether the investigational medicine is safe to use in treating type 1 diabetes. • Whether adding the investigational medicine is more effective in controlling blood glucose than insulin alone.
You may be able to join this study if you: • Are 18 years of age or older and you have had insulin-dependent type 1 diabetes for at least a year. • Are willing to take a study medicine in addition to your insulin therapy. • Have an HbA1c level that falls within the range required by the study. • Have a good understanding of your disease and the ability to manage it and are willing to undergo study assessments.
7/27/2016Gland and Hormone Related Diseases
The Hot Flash Study
Our team is evaluating non-hormonal investigational medication, to see if it helps reduce the frequency and severity of hot flashes in post menopausal women ages 40 to 65
Have gone through menopause Are between the ages of 40 and 65 Are extremely bothered by frequent hot flashes Are willing to keep a record of your daily hot flashes (a handheld electronic diary similar to a smart phone will be provided to help you do this)
7/27/2016Urinary Tract, Sexual Organs, and Pregnancy Conditions
Do you have headaches?
The University of Colorado is participating in a research study to determine if thoracic spine thrust manipulation alone is beneficial in the treatment of cervicogenic headaches. This project will see if this treatment can aid in reducing pain from these headaches.
You may be eligible to participate in this study if you answer yes to the following questions: - Do you have headaches that are mostly on one side which are associated with neck pain? - Are these headaches worse with movement or certain neck positions? - Do you have these headaches at least once a week for at least the last 2 months? - Are you between 18-60 years of age? - Can you come to physical therapy up to 6 times within a 30 day period? You may be ineligible to participate in this study if you have: - Rheumatoid arthritis - Osteoporosis - Broken bones in your neck or shoulder - A prolonged history of steroid use - A history of whiplash injury within the past six weeks
7/27/2016Muscle, Bone, and Cartilage Diseases
EFFECTS OF TESTOSTERONE THERAPY IN YOUNG ADOLESCENTS WITH KLINEFELTER SNDROME (47.XXY)
This study will study the effects of testosterone therapy on behavior, mood, problem solving, attention span, and motor skills in adolescent males with Klinefelter syndrome in early puberty. During this period in early puberty there is a lot of variability in how and when doctors start testosterone therapy. This study will evaluate if there are benefits to starting testosterone therapy in early puberty.
Participants with Klinefelter syndrome in early puberty (around age 10-15).
7/26/2016 
Volunteers with Alzheimer’s Disease Needed for Memory Study
To examine the safety and efficacy of the study drug, Sargramostim (Leukine®), on memory in adults with Mild-to-Moderate Alzheimer’s Disease.
1. Age 55 to 85 years; 2. Should have a mild-to-moderate Alzheimer's Disease diagnosis (Mini-Mental State Examination 10-26 inclusive); 3. If on anti-dementia treatment should be on stable treatment for at least 2 months (i.e. cholinesterase inhibitor and/or Memantine or Axona); 4. Stable on all other medications for at least 30 days prior to screen; 5. Should be fluent in English; 6. Should be physically able to participate by medical history, clinical exam and tests; 7. Should have a study partner to accompany them to scheduled visits.
7/26/2016 

​Additional Clinical Trails

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RANDOMIZED PHASE III COMPARISON OF STANDARD DOSE (60 GY) VS HIGH DOSE (74 GY) CONFORMAL RADIOTHERAPY WITH CONCURRENT AND CONSOLIDATION CARBOPLATIN/PACLITAXEL +/- CETUXIMAB IN PATIENTS WITH STAGE IIIA/IIIB NON SMALL CELL LUNG CANCER
Kavanagh, Brian D07-0851
NEW TRENDS IN HIV-RELATED RISKY PATTERNS OF INJECTING DRUG USE AND DRUGS DISTRIBUTION IN FOUR EURASIAN COUNTRIES WITH SUBSTANTIAL PRESENCE OF ATDS
Booth, Robert E08-1117
Helping Ourselves, Helping Others: The Young Womens' Breast Cancer Study
Borges, Virginia F. M.D.08-1222
S0931, "EVEREST: EVErolimus for Renal Cancer Ensuing Surgical Therapy, a Phase III Study"
Lam, Elaine Tat M.D.11-0545
GOG 9923 - A PHASE I STUDY OF INTRAVENOUS CARBOPLATIN/PACLITAXEL OR INTRAVENOUS AND INTRAPERITONEAL PACLITAXEL/CISPLATIN IN COMBINATION WITH CONTINUOUS OR INTERMITTENT / /CTEP SUPPLIED AGENT ABT-888 (NSC #737664) AND CTEP-SUPPLIED AGENT BEVACIZUMAB (NSC #704865) IN NEWLY DIAGNOSED PATIENTS WITH PREVIOUSLY UNTREATED EPITHELIAL OVARIAN, FALLOPIAN TUBE OR PRIMARY PERITONEAL CANCER
Guntupalli, Saketh Ram11-0636
A Phase II Study of the Aurora and Angiogenic Kinase Inhibitor ENMD-2076 in Previously Treated Locally Advanced and Metastatic Triple-Negative Breast Cancer
Diamond, Jennifer R M.D.11-0684
Identifying Unique Risks to Pregnancy In Perinatally Infected HIV Positive Women
Weinberg, Adriana11-1653
Oncofertility Patient Registry
Kondapalli, Laxmi A12-0389
An International Phase 3, Randomized Trial of Autologous Dendritic Cell Immunotherapy (AGS-003) Plus Standard Treatment of Advanced Renal Cell Carcinoma (ADAPT)
Lam, Elaine Tat M.D.13-1546
A phase II study of ponatinib in cohorts of patients with lung cancer preselected using different candidate predictive biomarkers.
Camidge, David Ross MD, PhD13-2002
A Phase 2B Randomized, Controlled, Multicenter, Open-Label Study of the Efficacy and Immune Response of GVAX Pancreas Vaccine (with Cyclophosphamide) and CRS-207 Compared to Chemotherapy or to CRS-207 Alone in Adults with Previously Treated Metastatic Pancreatic Adenocarcinoma
Weekes, Colin Dexter13-3144
Vascular mechanisms for the effects of loss of ovarian hormone function on cognition in women
Hildreth, Kerry L. MD14-0193
A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study Assessing the Effect of Gelesis100 on Body Weight in Overweight and Obese Subjects with and without Type 2 Diabetes. Sponsor Protocol No. G-04. WIRB Protocol No. 20150046
Hill, James O PhD14-0383
Reclaim Deep Brain Stimulation Therapy for Obsessive-Compulsive Disorder
Abosch, Aviva M.D.14-0554
A Phase I Trial of Inhaled Iloprost for the Prevention of Lung Cancer in Former Smokers
Miller, James York E M.D.14-1247
LIBERTY 360: Prospective, Observational, Multi-Center Clinical Study to Evaluate Acute & Long Term Clinical & Economic Outfomes of Endovascular Device Intervention in Patients with Distal Outflow Peripheral Arterial Disease (PAD)
Armstrong, Ehrin14-1522
Multicenter, open-label, randomized, controlled phase III clinical study of the efficacy and safety of photodynamic therapy using porfimer sodium for injection as treatment for unresectable advanced perihilar cholangiocarcinoma Sponsor Protocol No. PIN-PHO1201 WIRB Protocol No. 20140456
Shah, Raj Jay M.D.14-1650
Functional Avoidance Radiation Therapy for Lung Cancer Patients
Vinogradskiy, Yevgeniy14-1856
Self-reported usage patterns of opioid analgesic medications after surgery
Bartels, Karsten14-1938
Pilot study of a surgery and chemotherapy-only approach in the upfront therapy of children with WNT positive standard risk medulloblastoma
Dorris, Kathleen McCarthy O'Toole14-2097
Analysis of cataract surgery outcomes performed at the Children's Hospital Colorado from January 2005 through October 2014
Singh, Jasleen14-2183
A PHASE 3B RANDOMIZED STUDY OF LENALIDOMIDE (CC-5013) PLUS RITUXIMAB MAINTENANCE THERAPY FOLLOWED BY LENALIDOMIDE SINGLE-AGENT MAINTENACE VERSUS RITYUXIMAB MAINTENANCE IN SUBJECTS WITH RELAPSED/REFRACTORY FOLLICULAR, MARGINAL ZONE OR MANTLE CELL LYMPHOMA
Bowles, Daniel W14-2282
Protocol for the Evaluation of Dario™ BGMS Performance at Elevated Altitude. Sponsor Protocol No. CP-0003; WIRB Protocol No. 20142637
Garg, Satish K14-2330
Use of Ultrasonic Bone Scalpel in Adolescent Idiopathic Scoliosis - Randomized Clinical Trial
Garg, Sumeet15-0036
A DOUBLE-BLIND, PLACEBO-CONTROLLED RANDOMIZED TRIAL TO STUDY THE VIASKIN MILK EFFICACY AND SAFETY FOR TREATING IgE-MEDIATED COW’S MILK ALLERGY IN CHILDREN (MILES STUDY) Sponsor Protocol No. MILES WIRB Protocol No. 20141789
Fleischer, David Mark M.D.15-0140
ABT-414 Alone or ABT-414 Plus Temozolomide versus Lomustine or Temozolomide for Recurrent Glioblastoma; a Randomized Phase II Study of the EORTC Brain Sponsor Protocol No. MI4-483 WIRB Protocol No. 20142384
Damek, Denise Marie15-0164
A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of Rivipansel (GMI-1070) in the Treatment of Vaso-Occlusive Crisis in Hospitalized Subjects with Sickle Cell Disease
Hassell, Kathryn L M.D.15-0391
Predicting the Safety and Effectiveness of Inferior Vena Cava Filters (PRESERVE) Sponsor Protocol No. G140045 P WIRB Protocol No. 20150996
Rochon, Paul J M.D.15-0537
Reproductive and Sexual Health Issues in Young Women with CF: A Patient Survey
Sagel, Scott D MD, PhD15-0575
In-Clinic Feasibility Study to Observe the Closed Loop System. Sponsor Protocol No. CEP273/Z25. WIRB Protocol No. 20130443
Slover, Robert H. M.D.15-0684


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