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Clinical Trials

Volunteer to Be Part of a Research Study

Page through all School of Medicine clinical and research trials below. There are two categories:

  • Detailed Trial Descriptions, submitted by researchers, includes trial specifics and contact information.

  • Additional Clinical Trials, which include basic study details. To contact the researcher either Google the PI (primary investigator) name or use our campus directory.

If you are a researcher seeking volunteers and your study is not posted, please
submit your Web ad here.
  

Detailed Trial Descriptions

 Results From Research and Clinical Trials : Selected site
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Are you stopping your birth control because you want to become pregnant? 13-1594
To look at contraception rates after birth control discontinuation.
Women 18-35 who are planning to, or have recently stopped their birth control because they want to become pregnant.
PI: Teal, Stephanie
  • 303-724-2013
  • Sandra.cano@ucdenver.edu
Type 1 Diabetes Research Study 11-0649
To study the effects of a medication on metabolism and blood vessel function.
Persons 25-50 years old with or without type 1 diabetes with normal blood pressure and exercise vigorously no greater than 3 times per week.
PI: Schauer, Irene
  • 303-724-3976
  • Donald.Cohen@ucdenver.edu
JUST DIAGNOSED WITH SHINGLES? 13-2122
This study will look at the body's immune response (how the body fights infection) to the onset of shingles. 1-2 study visits for blood draws, over the course of 3 months.
18+ years of age; NO PRIOR HISTORY of shingles; have NEVER received the shingles vaccine; have DEVELOPED SHINGLES within the last 10 days.
PI: Levin, Myron
  • 303/724-2454
  • nancy.lang@ucdenver.edu
protein and infant growth: Do you have a child younger than 6 months 14-0139
Participants in this research study on protein from complementary foods (meat or dairy) and infant growth, will learn how protein consumption affects your child’s growth, fat gain, and gut health from 6 to 12 months of age.  
To qualify, you child needs to be: 1. Formula fed, or not on breast-milk longer than 1 month. 2. Younger than 6 months. 3. Generally healthy. You will receive commercially available complementary foods for 7 months, Receive infant formula at no cost for 7 months, You will know your child's body fat and fat free mass and blood lipid level.
PI: Krebs, Nancy
  • 303-724-3248
  • minghua.tang@ucdenver.edu
Volunteers Needed: Thinking and Memory in Parkinson's Disease 13-2724
This research study aims to better understand how changes in brain activity may be related to thinking problems in Parkinson's Disease and to determine whether, by stimulating certain areas, thinking and memory can be improved.
Person's with Parkinson's Disease with mild thinking and memory problems. Between 40-90 years old. No metal in your body. No implant. Not taking any medication to improve memory. Not taking stimulants or seizure medication.
PI: Kluger, Benzi
  • 303.724.4400
  • Benzi.Kluger@ucdenver.edu
Research Participants Needed 14-0770
We are looking for participants with diabetes to serve as a standard for comparison when describing physical function outcomes before and during prosthetic rehabilitation.
Inclusion Criteria: 1) 50-85 years of age. 2) Able to walk continuously without assistance (i.e., do not use a cane or walker) for 10 minutes and physically active (e.g., participate in recreational activities like walking, jogging, hiking). 3) Diagnosis of diabetes. 4) No other neurological, vascular or cardiac problems that limit function. 5) Body mass index
PI: Christiansen, Cory
  • 303-724-9590
  • krista.m.sanchez@ucdenver.edu
HAVE YOU OR YOUR CHILD BEEN DIAGNOSED WITH ASTHMA? HS-2827
We are looking for volunteers to participate in an N.I.H. funded research study.
Children 12 years of age and older and non-smoking Adults who have mild to moderate asthma who are not currently taking inhaled steroid medication
PI: Martin, Richard
  • 303-398-1443
  • martinlab@njhealth.org
Do You or Someone You Know Suffer From Relapse Remitting Multiple Sclerosis (RRMS)? 13-2209
The University of Colorado Denver is conducting a clinical trial to evaluate the effectiveness, safety and tolerability of two doses of oral administration of laquinimod in subjects with Relapse Remitting Multiple Sclerosis (RRMS). Patients that suffer from RRMS may experience a gradual increase of their disability over time. The purpose of this study is to find out whether laquinimod is safe and effective in slowing the rate of disability progression.
-Between the ages of 18 and 55 -Have clinically confirmed diagnosis of Multiple Sclerosis (MS) with relapse onset disease or relapsing-remitting disease course -Have had at least one documented relapse within 12 months prior to starting this study -Have not been treated with Natalizumab (Tysabri) or Rituximab 2 years prior to starting this study
PI: Vollmer, Timothy
  • 303-724-6351
  • Nicola.Haakonsen@ucdenver.edu
Sedentary Behavior Research Study 14-0429
This research study plans to learn more about how the time we spend seated affects your health
Healthy male and female Age: 19-45 With BMI: 27-33 you may check this at: http://nhlbisupport.com/bmi/ Be seated more than 6hr/d Be physically active on less than 3-4 days/wk
PI: Bergouignan, Audrey
  • 303-724-9026
  • nathan.dejong@ucdenver.edu
Healthy Minority Volunteers Needed 13-0427
This study plans to learn more about how tenofovir and emtricitabine (Truvada) build up in cells in blood and hair. Participation will include two 12 week dosing periods separated by a 12 week washout period (total duration is 36 weeks). Eligible participants will be given the supply of medications for the study.
Documented negative testing for HIV and hepatitis B Not at risk for HIV Study population balanced by Caucasian, African-American, Hispanic race. African American and Hispanic participants are currently needed. Age 18-50 years Able to meet study personnel on Anschutz Medical Campus for directly observed dosing with study medication, or by audio-visual communication with a mobile cellular device when off Campus
PI: Anderson, Peter
  • 303-724-8296
  • ariel.hodara@ucdenver.edu
University of Colorado Recruiting Patients for a Clinical Research Study for Psoriasis 13-2720
The research study compares the effect of treatments, such as Humira and phototherapy, on inflammation in the body and cardiovascular disease. This study will look for systemic vascular inflammation in subjects enrolled in this study, with a test called FDG-PET/CT (Fluorodeoxyglucose-positron emission tomography computed tomography).
We are looking for males and females 18 years of age and older with a diagnosis of psoriasis for at least 6 months
PI: Armstrong, April
  • 720-848-3607
  • aleksandra.florek@ucdenver.edu
Volunteers Needed for Research Study 13-2035
The purpose of the study is to evaluate the effect of mental concentration on nerve and muscle excitability.
We are looking for healthy men and women aged 21-50 years who do not have neck or shoulder pain to participate in a research study.
PI: Maluf, Katrina
  • 3037240066
  • ANP.Lab@ucdenver.edu
Diabetic Male and Female Volunteers Needed for Exercise Research Study 06-0062
Evaluate exercise function during single leg calf exercise in people with or without type 2 diabetes
Healthy Adults 30-70 with Type 2 diabetes but not using insulin.  Must be a non-smoker who exercise no more than one time per week and have a BMI of 25-40
PI: Regensteiner, Judith
  • 303-724-2255
  • shawna.mcmillin@ucdenver.edu
Trouble Controlling your Type 2 Diabetes? 12-1529
Investigational non-surgical device that may help decrease blood sugar.
Adults 21-65 with type 2 Diabetes and not on oral medication, not taking insulin. Must have an A1C level of 8-10%, be overweight or obese and willing to attend study visits
PI: Wyatt, Holly
  • GI Dynamics
  • Jeanneanne.breen@ucdenver.edu
Project Safe - THE IMPACT OF MEDICAL MARIJUANA IN METROPOLITAN DENVER 11-0718
To learn more about the medical marijuana industry in Colorado and its relationship to health risk behaviors and healthcare.
Persons 18+ currently a medical marijuana patient or currently using non-medical marijuana
PI: Booth, Robert
  • 1-800-429-9240
  • Eric.Kovalsky@ucdenver.edu
Persons with active, moderate to severe ulcerative colitis needed 12-1408
This study is being conducted to investigate the efficacy of methotrexate in treating ulcerative colitis in patients that have active, moderate to severe colitis and have failed other types of therapies.
Inclusion: Ages 18-70 Ulcerative colitis has been diagnoses by routine criteria At least one of the following applies: steroid dependent failed 5-ASA (mesalamine) therapy, such as Asacol Failed/lost response to infliximab (Remicade) Intolerant/unresponsive to azathioprine (Imuran) or 6-MP (purinethol) therapy Exclusion (partial): Existing pregnancy, lactation, or planned pregnancy (men and women)
PI: Gerich, Mark
  • 303-724-7875
  • katelyn.cowan@ucdenver.edu
3D Gait Analysis Participants Needed 13-1857
Research study investigating the coordination of walking
Subject with Spastic Cerebral Palsy Inclusion Criteria: ● Males and females between the ages of 7 and 100 years of age. ● Retrospective gait data must contain a complete lower body marker set and valid kinetic data. ● Only gait data trials of the subject walking unassisted will be used. ● Diagnosis of spastic cerebral palsy. ● Exhibits either stiff knee gait pattern, characterized by insufficient and delayed peak knee flexion during swing (less than 45), or crouch gait pattern, characterized by excessive hip flexion and knee flexion (greater than 30 throughout stance). Cerebellar Ataxic Gait Subject Inclusion Criteria: ● Males and females between the ages of 7 and 100 years of age. ● Ability to walk continuously and unassisted for 3 minutes. ● If under the age of 18, parent consent and subject assent. ● Diagnosis of either Friedreich's or spinocerebellar ataxia. Subject with Lower Limb Amputation Inclusion Criteria: ● Males and females between the ages of 7 and 100 years of age. ● Ability to walk continuously and unassisted for 3 minutes. ● If under the age of 18, parent consent and subject assent. ● Has been using the prosthetic limb for at least 6 months for independent ambulation prior to gait analysis at CGMA. ● Below knee or above knee amputation.
PI: Worster, Kate
  • 720-777-8216
  • worsterk@gmail.com
Would you like to participate in a study to improve the understanding of how emotions and symptom distress affect adherence to hormonal therapy in breast cancer? 13-0371
The purpose of this study is to understand how emotional factors and symptom distress affect adherence to hormonal therapy in women that have completed all other treatment for breast cancer.   
Women Breast Cancer Survivor Age 21-70 years old Within 24 months of starting hormonal therapy: Aromatase Inhibitors or Tamoxifen (Aromatase Inhibitors, Exemestane (aromasin), Letrolzole (Femara), Anastrozole (Arimidex).
PI: Grossman, Vicki
  • 720-352-3316
  • Vicki.Grossman@ucdenver.edu
Do you spend most of your day sitting? WIRB #20131967
The Anschutz Health & Wellness Center is seeking participants for a new research project to determine if exercise performed throughout the day is more energizing compared to exercise performed in the morning or if you do not exercise.
Participants must meet the following criteria: - Sedentary - Between the ages of 25 - 50 - BMI between 18.5 and 29.9 kg/m^2 - Non-smoker
PI: Hill, James
  • 303-724-8299
  • Eats.Study@ucdenver.edu
Pharmacokinetics Research Study of Nontuberculous Mycobacteria Antibiotics in HEALTHY people and in people with CYSTIC FIBROSIS 14-1043
We are conducting a research study to test if levels of antibiotics used to treat nontuberculous mycobacteria infections are different between people with and without cystic fibrosis. The goal of our study is to provide recommendations for treatment of CF patients with lung disease due to nontuberculous mycobacterial infection.
Teenagers and adults who are either healthy or who have cystic fibrosis and are 16 to 45 years old may be eligible to participate in this study.
PI: Martiniano, Stacey
  • 720-777-2945
  • Meg.Anthony@childrenscolorado.org
Have the Flu? Living with a chronic medical condition, too? 11-0101
Influenza (the flu) can be life-threatening. Approximately 24,000 people in the United States die each year of this disease. We are conducting a study to determine whether treating patients with a combination of several drugs instead of just one helps them to get better faster.
You qualify for our study if you: •Have been diagnosed with the flu •Are at least 18 years of age •Have an existing medical condition that puts you at increased risk for complications from the flu—conditions such as diabetes; heart, lung, and kidney disease; COPD; and asthma
PI: Barron, Michelle
  • 303-724-0712
  • Graham.Ray@ucdenver.edu
High Altitude Research Study 14-0620
Subjects needed for a study on how blood vessels in the lung are controlled at altitude
Male and Female subjects needed that are: • Between the ages of 18-49 years old and exercise regularly • Healthy: non smokers and not on medications • Willing to stay below 7,000 ft for 3 weeks prior to altitude chamber day
PI: Roach, Robert
  • 303-724-1674
  • altituderesearch@ucdenver.edu
Healthy Postmenopausal Women Needed for Cardiovascular Research Study 14-0532
The purpose of this study is to investigate how the health and function of arteries respond to estrogen, resveratrol, and exercise.
Postmenopausal women between the ages of 50-70 years, nonsmokers, not currently taking hormone replacement therapy or exercising vigorously more than 2 days per week.
PI: Moreau, Kerrie
  • 303-724-7465
  • cemal.ozemek@ucdenver.edu
Would your child like to participate in groundbreaking research and earn money? 12-1587
We are looking for healthy controls to participate in a research study investigating the cause of idiopathic scoliosis in adolescents.
Girls, 11-12 years old, do not have scoliosis or any other skeletal disorders, a BMI under 20 kg/m2, have not yet started their period, and have no family history of scoliosis
PI: Hadley Miller , Nancy
  • 720-777-4626
  • robin.baschal@childrenscolorado.org
Do you or someone you know have a food allergy to soy? 14-0097
We are studying the accuracy of a food allergy blood test.  
-Are age 1 to 21 and -Do have an IgE level greater than 0.35 to wheat OR soy or -Have had a positive skin test to wheat OR soy or -Have a clinically diagnosed wheat OR soy allergy -Do NOT use >500 micrograms/day fluticasone or equivalent -Do NOT have severe asthma, daily oral steroid dosing, or asthma requiring hospitalization within a year or an ER visit in the past 6 months -Do NOT have active EoE (or recently diagnosed) -Have NOT used biologic or allergen immunotherapy within the past year
PI: Fleischer, David
  • 720-777-2569
  • Hannah.Gilbert@childrenscolorado.org
Are you taking medications for diabetes and resulting kidney complications? 13-1419
To evaluate a new investigational drug for people with Type 2 diabetes and kidney disease.
Person 18+ who are not of child bearing potential (f female) with type 2 diabetes and currently taking medication for kidney disease. You must be able to attend at least 6 office visits over 16 weeks.
PI: Rasouli, Neda
  • 720-848-7174
  • T2DMresearch@ucdenver.edu
MS Volunteers Needed for Research Study 12-1388
Looking to see if there is a cognitive improvement with the treatment of oral estriol as compared to oral placebo.
We are looking for: • Women 18-50 years old • Diagnosed with definite relapsing-remitting, secondary-progressive multiple sclerosis or primary-progressive multiple sclerosis • MS disease duration of 15 years or less • On stable dose of standard MS treatment with Copaxone®, Betaseron® (or Extavia®), Rebif®,Avonex®, Gilenya®, Aubagio®, Tecfidera®, or no treatment ----You are not eligible for the study if you are pregnant, breast-feeding, smoke, or have other serious medical conditions.
PI: Corboy, John
  • Barby Halliday 303-724-4717
  • barbetta.halliday@ucdenver.edu
Apoyo con Cariño: Improving Palliative Care for Latinos with Cancer 12-0592
We want to understand if a patient navigator can help Latino patients and their family caregivers deal with cancer. Our project hopes to improve palliative or comfort care to patients with advanced cancer. The goal is to prevent or relieve suffering for people facing serious illness. Research is needed to find out if a patient navigator can help patients and family caregivers.
Adults (18 years and older) who self-identify as Latino and have Stage III-IV cancer.
PI: Fischer MD, Stacy
  • 303-724-7410
  • danielle.kline@ucdenver.edu
Seeking Adults with NO History of Eczema, Allergies or Asthma HS-2581
The purpose of this study is to determine why some individuals with atopic dermatitis are at increased risk for skin infections.
Males and females between 18 and 64years of age with no history of Allergies, Eczema, or Asthma
PI: Leung, Donald
  • 303-270-2222
  • lairsmithj@njhealth.org
SPIROMICS-Subpopulations and Intermediate Outcome Measures in COPD Study HS-2678
To identify subpopulations of COPD patients in order to develop newer and more effective treatments and to clearly define measureable end points so that treatment effects may be accurately assessed in a shorter period of time.
Be willing to undergo study procedures Be between the age of 40 and 80 years old Have smoked fewer than one pack of cigarettes per day for one year OR have smoked more than one pack of cigarettes per day for 20 years
PI: Bowler, Russell
  • 303-270-2827
  • HerrudT@njHealth.org

​Additional Clinical Trails

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NSABP B-31 A RANDOMIZED TRIAL COMPARING THE SAFETY AND EFFICACY OF ADRIAMYCIN AND CYCLOPHOSPHAMIDE FOLLOWED BY TAXOL (AC-T) TO THAT OF ADRIAMYCIN AND CYCLOPHOSPHAMIDE FOLLOWED BY TAXOL PLUS HERCEPTIN (AC-T+H) IN NODE-POSITIVE BREAST CANCER PATIENTS WHO HAVE TUMORS THAT OVEREXPRESS HER2
Kounalakis, Nicole00-236
SWOG N9831 PHASE III TRIAL OF DOXORUBICIN AND CYCLOPHOSPHAMIDE (AC) FOLLOWED BY WEEKLY PACLITAXEL WITH OR WITHOUT TRASTUZUMAB AS ADJUVANT TREATMENT FOR WOMEN WITH HER-2 OVEREXPRESSING NODE POSITIVE OR HIGH-RISK NODE NEGATIVE BREAST CANCER
Elias, Anthony00-954
GOG#184 - A RANDOMIZED PHASE III STUDY OF TUMOR VOLUME DIRECTED PELVIC PLUS OR MINUS PARA-AORTIC IRRADIATION FOLLOWED BY CISPLATIN AND DOXORUBICIN OR CISPLATIN, DOXORUBICIN AND PACLITAXEL FOR ADVANCED ENDOMETRIAL CARCINOMA
Davidson, Susan01-101
A RANDOMIZED PHASE II CHEMOPREVENTION STUDY OF ILOPROST VERSUS PLACEBO IN PATIENTS AT HIGH RISK FOR LUNG CANCER
Keith, Robert01-279
A STUDY OF THE EFFECTIVENESS AND TOLERABILITY OF WEEKLY RIFAPENTINE/ISONIAZID FOR THREE MONTHS VERSUS DAILY ISONIAZID FOR NINE MONTHS FOR THE TREATMENT OF LATENT TUBERCULOSIS INFECTION [TBTC STUDY 26]
Gardner, Edward01-284
AUTOLOGOUS PAP-LOADED DENDRITIC CELL VACCINE (APC 8015, PROVENGE) IN PATIENTS WITH NON-METASTATIC PROSTATE CANCER WHO EXPERIENCE PSA ELEVATION FOLLOWING RADICAL PROSTATECTOMY IN RANDOMIZED, CONTROLLED, DOUBLE-BLIND TRIAL
Glode, Michael01-348
CHOLESTEROL AND ANTIOXIDANT TREATMENT IN PATIENTS WITH THE SMITH-LEMLI-OPITZ SYNDROME (SLOS)
Elias, Ellen01-410
A PHASE II STUDY OF ADJUVANT STI571 (GLEEVEC) THERAPY IN PATIENTS FOLLOWING COMPLETELY RESECTED HIGH-RISK PRIMARY GASTROINTESTINAL STROMAL TUMOR (GIST)
McCarter, Martin01-879
ANBL0032 PHASE III RANDOMIZED STUDY OF CHIMERIC ANTIBODY 14.18 (CH 14.18) IN HIGH RISK NEUROBLASTOMA FOLLOWING MYELOABLATIVE THERAPY AND AUTOLOGOUS STEM CELL RESCUE
Greffe, Brian01-932
RTOG 96-01 A PHASE III TRIAL OF RADIATION THERAPY WITH OR WITHOUT CASODEX IN PATIENTS WITH PSA ELEVATION FOLLOWING RADICAL PROSTATECTOMY FOR PT3NO CARCINOMA OF THE PROSTATE.
Rabinovitch, Rachel02-182
DIABETES PREVENTION PROGRAM OUTCOMES STUDY (DPPOS)
Dabelea, Dana02-498
ACOSOG Z9001: A PHASE III RANDOMIZED DOUBLE-BLIND STUDY OF ADJUVANT STI571 (GLEEVEC) VERSUS PLACEBO IN PATIENTS FOLLOWING THE RESECTION OF PRIMARY GASTROINTESTINAL STROMAL TUMOR (GIST)
McCarter, Martin02-607
EFFICACY OF AGGRESSIVE RENIN-ANGIOTENSIN-ALDOSTERONE AXIS BLOCKADE IN PREVENTING/SLOWING RENAL FUNCTION DECLINE IN ADPKD
Schrier, Robert02-744
RANDOMIZED EVALUATION OF RECURRENT STROKE COMPARING PFO CLOSURE TO ESTABLISHED CURRENT STANDARD OF CARE TREATMENT - RESPECT TRIAL
Anderson, Clark02-805
A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, MULTICENTER PHASE III STUDY COMPARING GW572016 AND LETROZOLE VERSUS LETROZOLE IN SUBJECTS WITH ESTROGEN/PROGESTERONE RECEPTOR-POSITIVE ADVANCED OR METASTATIC BREAST CANCER (EGF 30008).
Elias, Anthony03-1030
A CONTINUATION PROTOCOL FOR PI-88 IN PATIENTS WITH ADVANCED MALIGNANCIES
Eckhardt, Sue03-1250
AALL0031 A CHILDREN'S ONCOLOGY GROUP PILOT STUDY FOR THE TREATMENT OF VERY HIGH RISK ACUTE LYMPHOBLASTIC LEUKEMIA IN CHILDREN AND ADOLESCENTS
Giller, Roger03-239
IMPAACT P1026s: Pharmacokinetic Properties of Antiretroviral and Related Drugs During Pregnancy and Postpartum, Version 8.0
McFarland, Elizabeth03-546
PROSPECTIVE MULTICENTER EVALUATION OF THE DURATION OF THERAPY FOR THROMBOSIS IN CHILDREN
Wang, Michael03-585
TREATMENT OPTIONS FOR TYPE 2 DIABETES IN ADOLESCENTS AND YOUTH
Zeitler, Philip03-595
AHOD0031, A PHASE III GROUP-WIDE STUDY OF DOSE-INTENSIVE RESPONSE-BASED CHEMOTHERAPY AND RADIATION THERAPY FOR CHILDREN AND ADOLESCENTS WITH NEWLY DIAGNOSED INTERMEDIATE RISK HODGKIN DISEASE
Garrington, Timothy03-683
COLORECTAL CHEMOPREVENTION WITH CALCIUM AND VITAMIN D (THE VITAMIN D/CALCIUM POLYP PREVENTION STUDY)
Ahnen, Dennis03-993
CLINICAL CORRELATION AND COST ANALYSIS OF SICKLE CELL PATIENTS UNDERGOING CHRONIC ERYTHROCYTAPHERESES.
Hassell, Kathryn04-0005
A PHASE II MULTICENTER STUDY TO EVALUATE THE EFFICACY AND SAFETY OF 500 MG OF FULVESTRANT (FASLODEX) AS A FIRST LINE HORMONAL TREATMENT IN POSTMENOPAUSAL WOMEN WITH HORMONE RECEPTOR POSITIVE METASTATIC BREAST CANCER.
Borges, Virginia04-0303
Use Of 3,4-Diaminopyridine (3,4-Dap)In The Treatment Of Lambert-Eaton Syndrome (Lems)
Ringel, Steven04-0567
MET FULLY IMPLANTABLE OSSICULAR STIMULATOR
Jenkins, Herman04-0579
ACNS0331: A STUDY EVALUATING LIMITED TARGET VOLUME BOOST IRRADIATION AND REDUCED DOSE CRANIOSPINAL RADIOTHERAPY (18.00 GY) AND CHEMOTHERAPY IN CHILDREN WITH NEWLY DIAGNOSED STANDARD RISK MEDULLOBLASTOMA: A PHASE III DOUBLE RANDOMIZED TRIAL
Foreman, Nicholas04-0625
DOUBLE-BLIND TRIAL OF CHOLINE DURING PREGNANCY AND RISK FOR SCHIZOPHRENIA
Ross, Randal04-0678
A STUDY OF THE EVALVE CARDIOVASCULAR VALVE REPAIR SYSTEM (CVRS) ENDOVASCULAR VALVE EDGE-TO-EDGE REPAIR STUDY
Carroll, John04-0831
INSULIN RESISTANCE INTERVENTION AFTER STROKE (IRIS) TRIAL
Hughes, Richard04-0855


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