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Clinical Trials

Volunteer to Be Part of a Research Study

Page through all School of Medicine clinical and research trials below. There are two categories:

  • Detailed Trial Descriptions, submitted by researchers, includes trial specifics and contact information.

  • Additional Clinical Trials, which include basic study details. To contact the researcher either Google the PI (primary investigator) name or use our campus directory.

If you are a researcher seeking volunteers and your study is not posted, please
submit your Web ad here.
  

Detailed Trial Descriptions

 Results From Research and Clinical Trials : Selected site
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COMIRB Approved Advertisement TitleStudy GoalsEligibility CriteriaDate PostedCategory
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SPIROMICS-Subpopulations and Intermediate Outcome Measures in COPD Study
To identify subpopulations of COPD patients in order to develop newer and more effective treatments and to clearly define measureable end points so that treatment effects may be accurately assessed in a shorter period of time.
Be willing to undergo study procedures Be between the age of 40 and 80 years old Have smoked fewer than one pack of cigarettes per day for one year OR have smoked more than one pack of cigarettes per day for 20 years
3/23/2017 
Healthy Female Adolescents Needed!!!
For brain imaging research study on how the brain works with we taste sweets or receive money. Your participation could help us to develop treatments and preventive measures for anorexia nervosa and obesity
Healthy females 11 to 21 who are right-handed, free of medication with no serious medical conditions, permanent metal implants or braces/retainers, and are at a healthy body weight.
3/23/2017 
A Study to Determine the Effectiveness of Seeing Dermatologist Online Compared to In-Person
The purpose of the study is to see whether seeing a dermatologist online is just as effective as seeing one in-person. Help us determine whether online-based model is cost-saving and more efficient compared to face-to-face visits!
In order to qualify for the study, you must be 18 years or older and have psoriasis. You must have access to the internet, and a digital camera or a mobile phone with a camera.
3/23/2017 
Do You or Someone You Care for Suffer from Troublesome Drooling?
A research study is being conducted to evaluate an investigational product for Sialorrhea (troublesome drooling).
You or your loved one may be eligible to participate if you meet the following criteria: 1. Have a diagnosis of Parkinson’s disease, adult cerebral palsy, ALS, stroke, traumatic brain injury, oral cancer, or side effects of medication, or any other condition that causes Sialorrhea or troublesome drooling 2. Have never received any type of treatment using Botulinum toxin type B 3. Have ability & availability to participate in a study for up to 1 year
3/23/2017 
Parkinson's Disease Research Study
clinical research study to look at the safety and effectiveness of an investigational medication, ADS-5102 (amantadine HCl) extended release capsules, for troublesome dyskinesia in subjects with Parkinson’s disease.
You may be eligible if you have Parkinson's Disease, currently take levodopa, and are experiencing troublesome dyskinesia (involuntary twisting and turning).
3/23/2017 
Type 2 Diabetes Medication Research Study
Studying the effects of sitagliptin (a diabetes medication) on exercise capacity in people with type 2 diabetes
-Be a man or woman between 22 and 70 years old -Be generally healthy, with type 2 diabetes -Be taking metformin only for your diabetes -Be a non-smoker -Have a Body Mass Index greater than 25.0
3/23/2017Nutritional and Metabolic Diseases
" EDEN "Estrogen, Diabetes and Endothelial Function
Study the effect of estrogen on blood vessels
CONTROL PARTICIPANT ELIGIBILITY · Age 18-45 · Premenopausal · Not using hormonal birth control currently or in the last 6 months (including oral contraceptives, contraceptive patch, Depo Provera, norplant, or IUD) · Not currently pregnant or planning to become pregnant in the next 3 months · No recent history of amenorrhea (no menstrual period for at least 3 months) during the last 6 months · Non-smoker · No antioxidant therapy (vitamin C or E or multivitamin) for at least 4 weeks prior to the first study visit   Normal thyroid function (can be treated)  T1D ELIGIBILITY  · Age 18-45 · Premenopausal · Have had type 1 diabetes for at least 5 years, were treated with insulin within a year of diagnosis, and are currently treated with insulin · Not using hormonal birth control currently or in the last 6 months (including oral contraceptives, contraceptive patch, Depo Provera, norplant, or  IUD) · Not currently pregnant or planning to become pregnant in the next 3 months · No recent history of amenorrhea (no menstrual period for at least 3 months) during the last 6months · Non-smoker · No antioxidant therapy (vitamin C or E or multivitamin) for at least 4 weeks prior to the first study visit  HbA1c < 9.5  Normal kidney function (urinary albumin excretion rate < 200 µg/min)         Normal thyroid function (can be treated)
3/23/2017Heart and Blood Diseases
Volunteers needed for functional MRI research study
Patients with schizophrenia are needed for a research study to learn more about how drugs used to treat illness symptoms affect weight gain and brain responses to food. We are also studying how exercise and diet affect these responses.
Diagnosis of schizophrenia/schizoaffective disorder; taking risperidone, olanzapine, or clozapine; capable of mild/moderate exercise; BMI less than 39; no heart problems or untreated high blood pressure; capable of MRI
3/23/2017Behaviors and Mental Disorders
Attention Teens! Are You Concerned About Gaining Too Much Weight During Pregnancy?
A research study at Children’s Hospital Colorado and Colorado State University seeks pregnant teenagers age 13-19y who may be at risk for gaining too much weight during pregnancy. Consider participating in this research study focused on testing a healthy pregnant weight gain program. The study involves 1 screening visit, 6 1-hour sessions during pregnancy or usual care, and follow-up visits within 3 months of having your baby. Eligible participants could be financially compensated up to $200-$250 for their time and inconvenience.
Female 13-19 years old Pregnant
3/23/2017--Select a Category--
Physically active women and men needed for a research study on PTH and Calcium Responses to Exercise in Older Adults Experiment 2 (PACE Sr. 2)
To determine if stopping the decrease in blood calcium during exercise impacts markers of calcium loss from the bone.
 A 60-80-year-old woman or man in generally good health  Often walk for exercise and can walk for an hour at a time  Not taking osteoporosis medication  No history of Diabetes or Cardiovascular Disease
3/23/2017--Select a Category--
Parent Perspectives on Transitioning Premature Infants from Tube Feeding to Oral Feeding: Focus Group Research
The purpose of this research study is to learn more about parent perspectives transitioning their premature infant from tube feeding to oral feeding.
Inclusion criteria: - Parent/caregiver of a child who was born prematurely (before 37 weeks) - Your child required tube feeding for at least the first three months of life - Your child is currently between 6 months and 5 years old Exclusion criteria: - Parent/caregiver is less than 18 years old
3/23/2017Diseases and Abnormalities at or before Birth
Parkinson's disease: Do visual problems cause fatigue?
Researchers from the University of Colorado Anschutz Medical Campus are conducting a study to investigate the relationship of eye movement and balance deficits with fatigue in people with Parkinson's disease.
Have clinically diagnosed idiopathic Parkinson's disease Are between 45 and 89 years old Are ale to walk independently without an assistive device
3/23/2017Nervous System Diseases
Research about the Effect of Isotretinoin (acne medication) on the Etonogestrel Contraceptive Implant (Implanon®/Nexplanon®)
To research the effect of Isotretinoin, a medication used for severe acne, on the contraceptive implant.
Are you a healthy woman between the ages of 18-45? Are you currently under the care of a Dermatologist and considering starting treatment with isotretinoin (Accutane®)? Do you currently have the birth control implant (Implanon®/Nexplanon®) or are you planning to use the birth control implant during isotretinoin (Accutane®) therapy?
3/23/2017Urinary Tract, Sexual Organs, and Pregnancy Conditions
Looking for HIV-positive & negative volunteers to participate in a research study on diet & gut microbiota
This study plans to learn more about the short-term effects of consuming either a Western style diet or Agrarian-style diet (A diet low in fat and high in fiber/carbohydrates) on inflammation in people with and without HIV.
We are seeking men and women volunteers who are:  Between the ages of 18 and 65  Have a BMI between 21-29 mg/kg2 and weight stable for past 3 months  Willing to follow assigned diet for 4 weeks  If HIV-positive, treated with ART for at least 12 months--no changes in drugs over past 6 months, and plasma HIV-1 RNA ≤50 copies/mL for past 6 months
3/23/2017--Select a Category--
We are looking for Healthy Women to participate in a research study on.....Females, Aging, Metabolism, and Exercise (FAME)
To examine the role that female sex hormones play in metabolism, energy expenditure, physical activity and chronic disease.
Healthy women 40-60 who have regular menstrual cycles and using no hormonal contraceptives
3/22/2017 
Do you have Diabetes?
To find the best combination drug treatment for type 2 diabetes
Persons who have had diabetes for less than 5 years and metformin is the only diabetes medication you are taking.
3/22/2017 
Type 1 Diabetes Research Study
To study the effects of an FDA-approved medication on metabolism and blood vessel function.
Person 25-50 with type 1 diabetes who exercise vigorously less than four times per week and have normal blood pressure
3/22/2017 
Just received VARIVAX, the chickenpox vaccine?
Research study looking at the immune response to chickenpox vaccine
Age 12 months to 50 years; able to enroll in study within 10 days of vaccination.
3/22/2017 
Healthy Hispanic Female Needed
For brain imaging research study on how the brain works with we taste sweets. Your participation could help us to develop treatments and preventive measures for anorexia nervosa and obesity
Healthy females 22 to 29 who are right-handed, free of medication with no serious medical conditions, permanent metal implants or braces/retainers, and are at a healthy body weight.
3/22/2017 
Looking for HIV-positive individuals to participate in a research study on Lipodystrophy Syndrome
We are conducting a study of the relationship of bacteria in the gut to HIV infection. We are interested in finding out whether people who have metabolic diseases such as lipodystrophy (loss of fat tissue) as complications of long term antiretroviral therapy have a different makeup of their gut bacteria. We are therefore seeking volunteers with HIV infection to participate in a study of bacteria in the stool.
-Non-obese HIV positive individuals who are 18-65 years old -Either not currently on antiretroviral therapy (ART naïve or off therapy for 6 months or greater) or on effective ART with documented suppression for 6 months or greater. -We are particularly interested in enrolling subjects with lipodystrophy, but would also like to enroll individuals without lipodystrophy as controls.
3/22/2017 
Looking for HIV-positive and HIV-negative men to participate in a research study on smoking and lung disease
We are conducting a study to look at lung complications and disease in HIV/AIDS.
-Between 30 and 70 years old -Both HIV-positive and HIV-negative individuals with and without chronic obstructive pulmonary disease (COPD) -If HIV-positive, on a stable three-drug ART regimen with undetectable viral load for past 6 months
3/22/2017 
GENETIC-AF
The GENETIC-AF is a trial that will investigate the safety and effectiveness of an investigational drug on the recurrence of symptomatic atrial fibrillation in people who have heart failure. The investigational drug will be studied versus an approved drug after patients receive an electrical cardioversion.
Adults who have symptomatic atrial fibrillation may be eligible.
3/22/2017Heart and Blood Diseases
Information for patients. Living with diabetes is complicated.
The FREEDOM-3S Study is a clinical research study that will involve approximately 126 patients in the United States. It will look at a potential new treatment option, the ITCA 650,for people with type 2 diabetes. The ITCA 650 is a small metal cylinder (about the size of a matchstick) that is placed under the skin of the abdomen (belly) to slowly release the study medication – exenatide. The FREEDOM-3S Study is looking at how safe and well tolerated two different doses of the ITCA 650 are in people with type 2 diabetes who are already taking liraglutide (also known as Victoza injections, and metformin.
You may be eligible to take part if you: • are 18–80 years of age • have been diagnosed with type 2 diabetes for at least 3 months • have been taking liraglutide (Victoza) injections and metformin every day for at least 3 months.
3/22/2017Gland and Hormone Related Diseases
Controlling blood glucose levels. Can be a real balancing act.
The EASE-3 clinical research study is a study in which doctors hope to learn: • Whether the investigational medicine is safe to use in treating type 1 diabetes. • Whether adding the investigational medicine is more effective in controlling blood glucose than insulin alone.
You may be able to join this study if you: • Are 18 years of age or older and you have had insulin-dependent type 1 diabetes for at least a year. • Are willing to take a study medicine in addition to your insulin therapy. • Have an HbA1c level that falls within the range required by the study. • Have a good understanding of your disease and the ability to manage it and are willing to undergo study assessments.
3/22/2017Gland and Hormone Related Diseases
Do you have headaches?
The University of Colorado is participating in a research study to determine if thoracic spine thrust manipulation alone is beneficial in the treatment of cervicogenic headaches. This project will see if this treatment can aid in reducing pain from these headaches.
You may be eligible to participate in this study if you answer yes to the following questions: - Do you have headaches that are mostly on one side which are associated with neck pain? - Are these headaches worse with movement or certain neck positions? - Do you have these headaches at least once a week for at least the last 2 months? - Are you between 18-60 years of age? - Can you come to physical therapy up to 6 times within a 30 day period? You may be ineligible to participate in this study if you have: - Rheumatoid arthritis - Osteoporosis - Broken bones in your neck or shoulder - A prolonged history of steroid use - A history of whiplash injury within the past six weeks
3/22/2017Muscle, Bone, and Cartilage Diseases
Rotator Cuff Clinical Research Study
The InSpace device is a balloon shaped implant made from a polymer, which is widely used material in the medical industry. The material is biodegradable meaning that following surgery it will gradually dissolve until it is completely absorbed at approximately one year following the implantation. During this time, the device is intended to support your shoulder healing allowing frictionless gliding between the shoulder bones which may improve shoulder muscle activity.
In order to participate, you must: Be 40 years of age or over and in general good health. Experiencing persisting shoulder pain for at least four (4) months which failed non-operative treatments such as: • Physical therapy • Activity modification • Rest (sling) • Anti-inflammatory medication Have had an MRI within 9 months that confirms a full thickness rotator cuff tear. Fulfill all study criteria as assessed by your surgeon and be willing to return for all follow-up visits.
3/22/2017--Select a Category--
EFFECTS OF TESTOSTERONE THERAPY IN YOUNG ADOLESCENTS WITH KLINEFELTER SNDROME (47.XXY)
This study will study the effects of testosterone therapy on behavior, mood, problem solving, attention span, and motor skills in adolescent males with Klinefelter syndrome in early puberty. During this period in early puberty there is a lot of variability in how and when doctors start testosterone therapy. This study will evaluate if there are benefits to starting testosterone therapy in early puberty.
Participants with Klinefelter syndrome in early puberty (around age 10-15).
3/21/2017 
Volunteers with Alzheimer’s Disease Needed for Memory Study
To examine the safety and efficacy of the study drug, Sargramostim (Leukine®), on memory in adults with Mild-to-Moderate Alzheimer’s Disease.
1. Age 55 to 85 years; 2. Should have a mild-to-moderate Alzheimer's Disease diagnosis (Mini-Mental State Examination 10-26 inclusive); 3. If on anti-dementia treatment should be on stable treatment for at least 2 months (i.e. cholinesterase inhibitor and/or Memantine or Axona); 4. Stable on all other medications for at least 30 days prior to screen; 5. Should be fluent in English; 6. Should be physically able to participate by medical history, clinical exam and tests; 7. Should have a study partner to accompany them to scheduled visits.
3/21/2017 
T•A•C•I•T - Therapy After Cochlear Implants Using Telemedicine
This research plans to learn more about the use of telemedicine as a means of providing therapy to children who have a cochlear implant(s). While Auditory-Verbal Therapy has typically been delivered in person, many people are starting to access therapy over the internet. We are conducting this research to determine if the outcomes of therapy are the same when AVT is delivered in person and via telemedicine.
The TA•C•I•T team is looking for children ages 6 mos.-6 yrs. old who were implanted with cochlear implant(s) before age  3 ½..  Each child will spend nine months in both the in-person and telemedicine condition. The therapist will remain the same throughout the study. Total participation will last 18 months. The child will be tested three times: once when the study starts, and every nine months after that. A qualified study team member will administer speech, listening, and language tests to the child. They will also receive tests to identify how well their auditory area of the brain is developing.
3/21/2017 
Participants with Chronic Kidney Disease Needed for a Research Study about Phosphate
We are looking for men and women to participate in a research study examining whether lowering blood levels of phosphate will improve blood vessel function.
We need men and women who:  -are age 40-79 years old; women must be post-menopausal;  -have chronic kidney disease stage 3b or 4 (estimated GFR 15-45 ml/min);  -are not taking phosphate binders;  -do not have high blood phosphate (>5.5 mg/dL).
3/21/2017 


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Brenda Crawford, Research Coordinator, (303) 724-5362

Building 500 - 13001 E. 17th Place, Campus Box C290, Aurora, CO 80045

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