We want to understand how RNA forms complex
three-dimensional structures and how this controls diverse biological processes.
We are particularly (but not exclusively!) interested in how viral RNAs
interact with, control, and manipulate cellular machines. Given the remarkable
diversity of viruses and viral RNAs, we are learning fundamental things about
the inherent properties and power of RNA structure, of how viruses cause
disease, and of the basic workings of the cell.
For more information on our research interests and projects in the lab,
please visit the Kieft Lab website.