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Novel Methods Development Pilot Program (NMD Pilot Program)​​

Past Awards


The CCTSI is pleased to announce the ​Novel Methods Development Pilot Program (NMD Pilot Program)​​ awardees. These positions are funded by the NIH/NCRR grant to the CCTSI.

 

 2017 NMD PILOT PROGRAM AWARDS

 
  
  
  
Project Title
  
Phase I
Novel Technology for Continuous Quantitative Monitoring of Uterine Tone
  
Willy Boucharel, Richard Pimentael, David PolanerPhase II
Multichannel Intraoperative EMG Recording of Myometrium for Continuous Montoring of Uterine Tone
  
Phase I
Measuring extracellular calcium contentration in the brain in-vivo
  
Phase II
Novel electrochemical sensors extracellular calcium measurements
  
Phase I
Pharmacokinetic and pharmacodynamic evaluation of targeted therapies in the pulmonary circulation
  
Phase II
Dosing, sampling and analysis of the pulmonary circulation for PK/PD studies of pulmonary therapies
  
Phase I
Development of RNA flow cytometry analysis for genomic Zika virus RNA detection
  
Phase II
Identificaton and purification of virally-infected cells based on RNA expression
 

 2016 NMD PILOT PROGRAM AWARDS

 
  
  
  
Project Title
  
Phase I
Novel Durg Screening Method for Pulmonary Hypertension
  
Linfeng LiPhase II
3D culture models for high throughput drug discovery targeting pulmonary hypertension
  
Phase I
Imaging Technique to Correlate Inflamed Breast Cancer and Lymph Node Metastasis
  
Phase II
Non-Invasive Muli-Parametric MRI on Lymph Node Involvement and Inflammation Status in Breast Cancer
  
Phase I
Pathogen-Targeted Transcriptional Profiling in Human Samples:  A Tool for Monitoring Treatment Responses in Tuberculosis
  
Joe RussoPhase II
Novel method for selecting M.abscessus RNAs from infected human tissue samples
 

 2015 NMD PILOT PROGRAM AWARDS

 
  
  
  
Project Title
  
Phase I
Enhanced bio delivery of cystathionine as a treatment for acute liver disease failure, nephrotoxicity and vascular calcification
  
Phase II
Improving cystathionine in a manner which allows increased solubility and gradual release in vivo
  
Phase I
Sensory Gating with a Microelectrode during deep brain stimulation surgery
  
Phase II
Developing a method to measure auditory agting during deep brain stimulation surgery
  
Kathleen Gavin, Wendy KhortPhase I
Development of a method to distinguish human adipocytes arising from distinct progenitor cells
  
Nichole ReisdorphPhase II
Development of proteomics and metabolomics methods to distinguish between human adipocytes arising from distinct progenitor cells
  
Phase I
Targeted metabolomics of producs of bacterial ploycyclic aromatic hydrocarbon degradation in the nasal cavity
  
Phase II
Optimization and Validation of Mass Spectrometry-based Assays for the Measurement of Polycyclic Aromatic Hydrocarbons (PAHs) and their metabolites
 

 2014 NMD Pilot Program Awards

 
  
  
  
Project Title
Nguyen VuPhase I
Flow Cytrometric Analysis to Define Gut Microbiota
Xiaoli YuPhase II
Development of high affinity phage peptide probes for rapid identification and characterization of the microbiota subsets that contribute to graft-versus-host disease (GVHD) pathogenesis
Joseph HurtKathleen ConnellPhase I
Novel biomechanical measurements of the uterine cervix at parturition
Virginia FergusonMark RentschlerPhase II
Novel biomechanical measurements of the uterine cervix at parturition
Eoin McNameePhase I
Mouse colonography for non-invasive assessment of intestinal architecture during colitis and colitis associated colon cancer
Natalie SerkovaPhase II
Small Animal microCT Colongraphy and FDG-PET for Non-Invasive Imaginf of Colitis and Colitis Inflammation
Jane ReuschJudy RegensteinerPhase I
Development of non-invasive systemic vascular characterization for diagnosis and prognosis of systemic vascular disease
Kendall HunterPhase II
Echo- and MR-based quantitative assessment of the systemic vasculature
 

 2012 NMD Pilot Program Awards

 
  
  
  
Project Title
Pepper SchedinPhase I
Non-Invasive Macrophage Imaging in Breast Cancer Models
Natalie SerkovaPhase II
Iron Oxide Based T2-MRI for Imaging Macrophage Recruitment into Breast Cancer
Kristen UhlerPhase I
Audiologist needs novel method for advanced analysis techniques of auditory evoked potentials and computer programming to develop sound stimuli
Daniel TollinNathaniel GreenePhase II
Data acquisition and analysis software for measurements of mismatch negativity and acoustic change complex
Eric ClambeyPhase I
The development of histology-based flow cytometry for multi-parameter, quantitative analysis of cell pupulations in situ
Richard BenningerPhase II
Multi-parameter quantatative analysis of cellular populations in-situ
 

 2011 NMD Pilot Program Awards

 
  
  
  
Project Title
Anna IvanschenkoGordon LindbergPhase I
Multiplex Point-of-Care Diagnostic Anemia Testing in Critically Ill Burn Patients
Mark DuncanPhase II
Multiplex Point-of-Care Diagnostic Anemia Testing in Critically Ill Burn Patients
 

 2010 NMD Pilot Program Awards

 
  
  
  
Project Title
Dennis Voelker, PhDBob Murphy, PhD, School of Medicine, PharmacologyPhase II
A highly sensitive method for rapid and large-scale quantification of phosphatidylglycerol and phosphatidylinositiol in pulmonary surfactant from patients with acute and chronic lung diseases.
Daniel Tollin, PhDKanthaiah Koka, PhD, School of Medicine, Physiology and BiophysicsPhase II
Data acquisition and analysis software for smooth pursuit eye movement measurements in infants
Wenbo Zhou, PhDPhase II
Development of novel method to generate sensory neuron from human induced pluripotent stem (iPS) cells for varicella zoster virus infection and latency study
Mark Laudenslager, PhDPhase II
Salivary alpha amylase as a biomarker of acute stress reactivity
 

 2009 NMD Pilot Program Awards

 
  
  
  
Project Title
Lori A. Walker, PhDJohn S. Walker, PhDPhase II
New Methods for Assessing Human Blood Vessel Mechanical Function
Mark S. Brown, PhDPhase II
Development of a Magnetic Resonance Spectroscopy-Based Measure of GABA Concentrations for Studies of Neurodevelopment Disorders
Kai R. Larsen, PhDJintae Lee, PhD and Zoya Voronovich, University of Colorado BoulderPhase II
The Inter-Nomological Network for Behavioral Health
Lynne Bemis, PhDWon Park, PhD, University of Colorado Boulder, EngineeringPhase II
Gold Nanoparticle Assay for the Detection of Multiple MicroRNAs in Patient Samples

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