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University of Colorado Denver

Animal Care and Use Program


Requirements for Conduct of Research Involving Animals

(Note:  For new associates or associates who are newly assigned to approved protocols, it is suggestd that a PQ be scanned and forwarded to the IACUC e-mail addess so there is no delay in adding associates)

1. Program Orientation The orientation consists of three training modules/courses accessed via CU Skillport.  The first course, "Animal Program Orientation," is an introduction to the UC Denver Animal Program (IACUC).  The next two courses, "Disease Prevention and Control in the Animal Housing Facilities" and "Standard Operating Procedures" are specific to the UC Denver (and associated) animal facilities (OLAR).     See the webpage: (  for more information.    

You must complete all three courses with a passing grade of 80%.  The IACUC/OLAR offices will confirm your completion of the courses.

2. Occupational Health – contact 303-724-9145 to schedule an appointment.  Take your  your immunization records, your initial medical surveillance questionnaire, your employee ID # and a speedtype (account to which any tests/immunizations will be charged) to your appointment. Please see the Occupational Health page: for more information. 

Occupational health should also be updated annually.  See the annual recertification form on the occupational health page.

3. Qualifications to perform procedures on animals - send Personnel Qualifications (PQ) form to the IACUC e-mail After the Personnel Qualification (PQ) form is completed and signed by both the associate and the PI, it should be saved electronically so it can be updated as necessary and scanned into new protocol submissions.   See the sample and a blank form at Please fill out the form and use the sample form to help you complete it correctly.  Please see the website for copies of the forms.

4. When steps 1-3 are complete, the IACUC Coordinator will e-mail the PI requesting confirmation that the associate should be added to the protocol(s).

5. Associated on a Protocol When steps 1-4 are completed, the IACUC office will add a new associate to the appropriate protocol(s) and will e-mail Lorraine Bell (The OLAR training manager), and copy the associate and PI, to request a tour of the vivarium.   Please note that you should allow at least 1 week after completing all four steps before being added to a protocol(s) so it is important to complete these steps as quickly as possible.

Facility Access –  Once the tour and access practial are completed Ms. Bell will process your badge activation.

6.  Other:

a.  Web Animal Ordering -      For those personnel who need access to the online animal ordering system, please take the WAO Skillsoft Elements training module located at: .  After you have taken the course and passed the quiz and after being given permission by your PI to order animals, please email Daniel to inform him that you have passed the quiz, and provide him with the PI name and Protocol numbers for which you are authorized to order animals.

b. Online Protocol Software - TOPAZ - Access to TOPAZ is given to animal protocol Principal Investigators and up to a maximum of two additional members of their lab.  PIs must have a faculty level appointment in the CU system or at the VA or Denver Health.  At a minimum, a personnel qualifications form must be submitted to the IACUC office before access to TOPAZ is granted.  For further information, call the IACUC office at 303-724-1056 or email Researchers from outside the CU system/VA/Denver Health should call Dr. Mark Douse at 303-724-1057 for further assistance.

Anyone involved in animal procedures must complete the steps above.  Please contact the IACUC Office [303-724-1056] for more information.

In order to comply with Federal Regulations requiring the IACUC to ensure that those named on animal protocols are appropriately trained to perform the procedures listed on the protocol, updated personnel qualifications forms are to be attached to each new protocol submission in the online database.

Personnel Qualifications forms must contain up-to-date information on training, and signature dates must be concurrent with the submission.  The 'amount of experience' should define the number of months/years for which the procedures have been carried out and by whom training was provided.  If the associate does not have prior experience in a procedure, write “in training” for the ‘amount of experience” and who will train the associate in the ‘training” field.

The IACUC requires that the Personnel Qualifications form be completed and signed by the associate and then reviewed and signed off by the PI (to assure the IACUC that appropriate training for the procedures detailed on the protocol has taken place).  Please detail the procedures which will be the responsibility of the associate for each protocol number provided.  The IACUC Office advises that the PQ form information be typed and copies saved electronically to facilitate future updates and submissions.

Please be aware that workshops/classes on a number of topics on procedures involving animal manipulations are offered, with no charge to researchers, by the Animal Care Program.  Please see our training page for more information.

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