University of Colorado
Skaggs School of Pharmacy and Pharmaceutical Sciences
Mail Stop C238
12850 E. Montview Blvd. V20-4103
Aurora, CO 80045
Pharmacy and Pharmaceutical Sciences Building (V20)
Pharmacy and Pharmaceutical Sciences Building (V20)
Training and Education:
- PharmD, University of North Carolina at Chapel Hill
- Pharmacy Practice Residency, Shands Hospital at the University of Florida
- Post-PharmD Research Fellowship in Cardiovascular Pharmacogenomics, University of Florida College of Pharmacy
- Certificate in Clinical Science, University of Colorado Clinical Science Graduate Program
Dr. Aquilante's patient-oriented clinical research program is
aimed at identifying pharmacogenetic determinants of drug disposition,
response, and adverse effects in cardiovascular and metabolic diseases. Her
research has been funded by the National Institutes of Health, American Heart
Association, American College of Clinical Pharmacy, American Association of
Colleges of Pharmacy, pharmaceutical industry, and private foundations.
Currently, Dr. Aquilante’s clinical studies are focused on heart
transplant recipients and patients with advanced heart failure. The primary
goal of her work is to identify genetic predictors of drug disposition
(pharmacokinetics), response (pharmacodynamics) and adverse effects in heart
transplant recipients. She is also interested in identifying factors that
influence medication regimen complexity and adherence in the heart transplant
population. Recently, Dr. Aquilante has expanded her research program to
include a cross-disciplinary and translational component. This approach is
being used to elucidate mechanisms underlying left ventricular assist device
(LVAD)-related adverse effects in patients with advanced heart failure.
5915 Modern Drug Design and Action, Lecturer
6095 Pharmacotherapy 3, Lecturer
6915/7015 Seminar Research Course, Preceptor
7025 Pharmacogenomics (Entry-Level PharmD Program), Course Coordinator and
7995 Clinical Capstone, Lecturer
- P4 APPE
Rotation—Clinical Research and Pharmacogenomics
7780 Pharmacogenomics (North American-Trained and International-Trained PharmD
Programs), Course Coordinator and Lecturer
7310 Fundamentals of Pharmaceutical Sciences, Lecturer
7400 Ethical Issues in Toxicology and Pharmaceutical Sciences, Lecturer
7665 Pharmacokinetic Principles and Applications, Lecturer
6260 Conducting Clinical Trials for Investigators, Lecturer
7500 Practical Application of Molecular Biology Techniques for the Clinical
- EPID 6642, Genetics in Public Health, Lecturer
Professional Awards and Service:
- New Investigator Award,
American College of Clinical Pharmacy (2008)
- Chair, University of
Colorado School of Pharmacy Admissions Committee (2010-2014)
- Fellow, American College
of Clinical Pharmacy (2015)
- Vice Chair, Task Force on
Collaborative Research Opportunities, American College of Clinical Pharmacy
Inter-Society Coordinating Committee for Practitioner Education in Genetics and
Genomics (ISCC), National Human Genome Research Institute (NHGRI/NIH)
- Chair, Research Affairs Committee, American College of Clinical Pharmacy (2016-2017)
- Chair, Pharmacogenomics Special Interest Group (SIG), American Association of Colleges of Pharmacy (2017-2018)
- Co-Chair, Pharmacogenomics Implementation Committee Colorado (2016-present)
- Pharmacogenomics Certificate Program: Dr. Aquilante developed and teaches an online, practice-based, clinical pharmacogenomics certificate program for pharmacists, physicians and nurses. For more information: http://www.UCDenver.edu/Pharmacy/PGXCertificate
- International Clinical Pharmacogenomics Training Symposium: Dr. Aquilante developed and teaches a live, practice-based, clinical pharmacogeomics education symposium for pharmacists, physicians, and nurses. This program has been delivered at Children's Cancer Hospital Eqypt (57357) in Cairo, Eqypt.
- Aquilante CL, Niemi M, Gong L, Altman RB, Klein TE.
PharmGKB summary: very important pharmacogene information for cytochrome
P450, family 2, subfamily C, polypeptide 8.
- Aquilante CL, Page RL, Vu A, Roscoe N, Wolfel EE,
Lindenfeld JA. Comparison of Office, Home, and Ambulatory Blood Pressure in
Heart Transplant Recipients. J Card
Fail. 2014; 20(8):602-10.
- Bryant BM, Libby AM, Metz KR, Page RL II, Ambardekar AV,
Lindenfeld J, Aquilante CL. Evaluating patient-level medication regimen
complexity over time in heart transplant recipients. Ann
Pharmacother. 2016; 50(11): 926-934.
- Weitzel KW, Aquilante CL, Johnson S, Kisor DF, Empey PE. Educational strategies to enable expansion of pharmacogenomics-based care. Am J Health Syst Pharm. 2016; 73(23): 1986-1998.
- Deininger KM, Vu A, Page II, Ambardekar AV, Lindenfeld J, Aquilante CL. CYP3A pharmacogenetics
and tacrolimus disposition in adult heart transplant recipients. Clin Transplant. 2016; 30(9):1074-8.
- Cobretti MR, Page RL 2nd, Linnebur SA, Deininger KM, Ambardekar AV, Lindenfeld J, Aquilante CL. Medication regimen complexity in ambulatory older adults with heart failure. Clin Interv Aging. 2017: 12:679-686
- Jurgens PT, Aquilante CL, Page RL 2nd, Ambardekar AV. Perioperative Management of Cardiac Transplant Recipients Undergoing Noncardiac Surgery: Unique Challenges Created by Advancements in Care. Semin Cardiothorac Vasc Anesth. 2017 May 1 [Epub ahead
of print] PMID: 28466755.