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University of Colorado Denver

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PhD in Pharmaceutical Sciences

Curriculum Detail - Pharmaceutical Sciences and Biotechnology Track


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The following is a description of the core curriculum (basic science component) for the Pharmaceutical Sciences and Biotechnology track of the PhD program in pharmaceutical sciences.

Required Courses

PHSC 7310 Fundamentals of Pharmaceutical Sciences – 3 credits

  • Biophysical Approaches
  • Pharmaceutics/Formulation 101
  • Topics in Cell Biology
  • Pharmacokinetics
  • Pharmacogenomics
  • Basic Immunology

PHSC 7350 Molecular Interactions – 3 credits

  • Protein Structure
  • Protein Stability
  • Basic Enzymology
  • Protein Folding
  • Protein Thermodynamics

TXCL 7562 Analytical Basis of Forensic Toxicology – 2 credits

  • Chromatographic Theory
  • Chromatographic Practice: GC/HPLC/TLC
  • Basics of Immunoassays
  • Principles of Mass Spectrometry
  • Blood/Breath Ethanol Measurement
  • Application of all of the above to legal quantitation, pharmacokinetics, and effects of ethanol/cocaine/THC/amphetamines

PHSC 7652 Principles of Medicinal Chemistry – 2 credits

  • Fundamentals of Structure-Activity Relationships (SAR) 
  • Mechanisms of Drug Action Rational Drug Design 
  • Structure Effects of Drug Disposition SAR of Various Therapeutic Classes of Drugs

Other science courses commonly taken by our students include:

  • PHSC 7330 Issues in Drug Development – 2 credits
  • PHSC 7325 Pharmaceutical Development: Evaluating the External Environment – 2 credits
  • PHSC 7345 Principles of Drug Delivery – 2 credits
  • PHSC 7354 Structural Analysis of Biomolecules I – 2 credits
  • PHSC 7530 Cancer: Experimental and Medical Aspects- 2 credits
  • PHSC 7561 Pharmacology of Anti-Cancer Agents – 2 credits
  • PHSC 7609 Biophysics and Spectroscopy – 2 credits
  • PHSC 7649 Introduction to Modern Biotechnology – 1 credit
  • PHSC 7651/CHEN 5810 Pharmaceutical Biotechnology – 3 credits
  • PHSC 7653 Protein Formulation – 2 credits
  • PHSC 7660 Membrane Dynamics – 2 credits
  • PHSC 7831 Case Studies in Biotechnology – 2 credits
  • TXCL 7560 Drug Metabolism & Pharmacogenetics I – 3 credits
  • TXCL 7561 Drug Metabolism & Pharmacogenetics II – 3 credits

PLEASE NOTE THAT SOME REQUIRED COURSES IN THE PHARMACEUTICAL SCIENCES ARE TAUGHT EVERY OTHER YEAR. THE CURRENT SCHEDULE FOR THESE COURSES IS GIVEN BELOW.

Other Requirements

In addition, our students must complete:

  • Two research rotations in fall and spring semesters of their first year (PHSC 7650; 3 credits each)
  • Seminar in Pharmaceutical Sciences each semester (PHSC 7568; 1 credit/semester)
  • Ethical Issues in Toxicology and Pharmaceutical Sciences (PHSC 7400  – 1 credit)

 


Curriculum Detail - Clinical/Translational Track

Required Courses

  • PHSC 7310 Fundamentals of Pharmaceutical Sciences (3 credits)
  • TXCL 7560 Drug Metabolism and Pharmacogenetics  (3 credits)
  • PHSC/TXCL 7452 Introduction to Clinical Pharmacology  (3 credits)
  • BIOS 6648 Design of Clinical Trials and Experiments (2 credits)
  • CLSC 7150 Ethics and Regulation in Human Subjects Review (1 credit)

Other science courses commonly taken by our students include:

  • PHSC 7330 Issues in Drug Development (2 credits)
  • PHSC 7400 Ethical Issues in Toxicology and Pharmaceutical Sciences (1 credit)
  • PHSC 7652  Principles of Medicinal Chemistry (2 credits)
  • TXCL 7562  Analytical Basis of Forensic Toxicology (2 credits)
  • BIOS 6601 or BIOS 6611 Applied Biostatistics I or Biostatistical Methods I (3 credits)
  • BIOS 6602 or BIOS 6612 Applied Biostatistics II or Biostatistical methods II (3 credits)
  • CLSC 6260 Conducting Clinical Trials for Investigators (2 credits)
  • CLSC 6270 Critical Appraisal Seminars in Clinical Science (1 credit)
  • CLSC 7101 Grant Writing I (1 credit)
  • CLSC 7300 Scientific Grant Review Process:  CCTSI Proposals (1 credit)
  • CLSC 7500 Practical Application of Molecular and Cell Biology Techniques for the Clinical    Investigator (3 credits)
  • EPID 6630 Epidemiology (3 credits)
  • BIOS 6680 SAS Data Management and Database Design (3 credits)

Other Requirements

In addition, our students must complete:

  • PHSC 7568 Seminar in Pharmaceutical Sciences each semester (1 credit per semester)
  • PHSC 7650 Two research rotations, one in fall semester and one in spring semester of their    first year (3 credits per semester)

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