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University of Colorado Denver

University of Colorado Denver
 

DANA DABELEA, M.D., Ph.D.

Faculty Profile


Associate Professor

Department of Epidemiology

Colorado School of Public Health

University of Colorado Denver

 

Pediatric Diabetes

Grants: 1) CDC 1 U01 DP000247 “SEARCH for Diabetes in Youth”

                2) NIDDK 1R01 DK077131 “Spatial Epidemiology of Diabetes in Youth”

                3) NIDDK R01DK077949 “SEARCH Nutrition Ancillary Study”

               4)  JDRF 9-2007-1700 “SEARCH Monogenic Diabetes Study”

   5)  NIDDK  RO1 DK078542  “Subclinical cardiovascular disease in youth with type 1 diabetes”    

 

 

                                                DEVELOPMENTAL ORIGINS OF OBESITY

 

Grants: 1) NIDDK R01 DK068001 “Exploring the Fetal Origins Hypothesis in Diverse Youth”

               2) NIDDK R01 DK076648 “Exploring the fuel-mediated programming of neonatal growth”

               3) NICHD Contract No. HHSN275200800018C “National Children’s Study-Colorado Center”

 

Description of Research


   Dr. Dabelea’s main research interest is the understanding of the complex and multifactorial etiology of diabetes, both type 1 and type 2, especially among children and adolescents, with a goal of reducing, delaying and preventing its occurrence and burden. She is particularly interested in how early life risk factors, such as exposure to maternal diabetes during the intrauterine life, other exposures during fetal or early post-natal life, and infant growth and feeding patterns, influence the development of childhood obesity, insulin resistance, metabolic syndrome and diabetes

           

1-2 Most Significant Publications

1)    Dabelea D,  Mayer-Davis EJ, Lamichhane AP, D’Agostino RB Jr., Liese AD, Vehik KS, Venkat Narayan KM, Zeitler P, Hamman RF. Association of Intrauterine Exposure to Maternal Diabetes and Obesity with Type 2 Diabetes in Youth: The SEARCH Case-Control Study. Diabetes Care 2008; 31: 1422-6

2)    Dabelea D, D’Agostino R, Jr, Bell R, Johansen JM, Liu LL, Loots B, Marcovina S, Pettitt DJ, Imperatore G, Linder B, Mayer-Davis EJ, Waitzfelder B, for the SEARCH for Diabetes in Youth Study. Incidence of Diabetes in Youth in the US: The SEARCH for Diabetes in Youth Study. JAMA 2007; 297: 2714-2724

3)    Dabelea D, Hanson RL, Lindsay RS, Pettitt DJ, Imperatore G, Gabir MM, Roumain J, Bennett PH, Knowler WC: Intrauterine Exposure to Diabetes Conveys Risks for Type 2 Diabetes and Obesity: A Study of Discordant Sib-ships. Diabetes 2000;40:2208-1

 

 

Primary Focus Area (if part of the obesity initiative)

·         Developmental Origins of Obesity

 

Secondary Focus Areas (if part of the obesity initiative)

·         Obesity and metabolic dysregulation and co-morbities

 

Access to Specialized Populations

·         SEARCH for Diabetes in Youth registry

·         National Children’s Study

 

Benefit of CNRU

The major benefit of the CNRU for me is/will be the enhanced interaction and collaboration with other CNRU investigators. 

 

CNRU Cores Used

Metabolic

 

CNRU Collaborations

Eckel, Byers, Friedman, Grunwald, Hamman, Ogden.
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