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Translational Nexus Core


Mission Statement/Core Objective

The IDDRC Translational Neuroscience Nexus ('Nexus') is a patient registry, clinical database, and biological sample bank focused on developmental disorders. Its major goals are to advance research (i) by linking human cognitive, behavioral, neurological, and other clinical phenotypes to biological samples, especially DNA and (ii) by facilitating access to appropriate patient cohorts for research purposes.The Nexus is unique in that it emphasizes the inclusion of quantitative cognitive and behavioral data.

Advantages of Using the Nexus

​• Access established participants with both behavioral and genetic data
• Begin building a study cohort with no upfront costs
• Facilitate blood draws and biospecimen storage for new studies
Increase the likelihood of funding by providing access to an established population
• Decrease the time and expense associated with obtaining biospecimens


Clinical Data Registry. Participants enrolled in the Nexus give permission for their clinical data to be collected. This includes data from electronic medical records as well as rigorous psychological data, including autism evaluations and developmental assessments .
 
Nexus Biobank. Biological samples from each participant are stored in the secure AMC Biorepository Core Facility. Samples include serum, heparinized plasma, DNA, or immortalized lymphoblast cell lines. Other minimally invasive samples can be collected for a specific study under the Nexus protocol.
 
VIDEO: Translational Nexus Core
 

                  Are you interested in learning more about the Nexus?

                     Click here for Nexus Information for Investigators

                     Click here for Nexus Information for Families

                                                                               

 

 

Director:

​Co-Directors:

​Cordelia Robinson, PhD, RN

​Gessi Pino, MS, CGC (Enrollment)
Eric Moody, PhD (Informatics)
Gary Bellus, MD (Medical)

 

 

Contact the Colorado IDDRC

Phone: 303-724-3839 • Fax: 303-724-3838

Mailing Address: Mail Stop 8313, 12800 E. 19th Avenue • Aurora, CO 80045

E-mail: Peds.IDDRC@ucdenver.edu

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