Goal: To provide the IDDRC members with state-of-the-art services for the design and generation of genetically engineered mouse models of IDD. The vector facility constructs vectors to generate transgenic, knockout and knockin animals and vectors with tissue-specific promoters. Additional services include the screening of ES cells generated from gene targeting constructs. The IDDRC has teamed with the NINDS-funded Vector Core of the RMND Center to provide these services. W. Chick designs the constructs that are subsequently engineered by K. Williams. The ES cell and mouse work is done in collaboration with the Transgenic and Gene Targeting Core.
Contact: Wallace Chick, PhD
Video of Vector Construction Core
Prices: Transgenic Construct
Member: $1,552.28
Non member: $2,053.47
Prices: KI, KO, BAC Transgenic Construct
Member: $2,195.07
Non member: $3,173.60
Prices: Conditional KO Construct
Member: $2,259.35
Non member: $3,285.61
The price for vector construction includes initial consultation with client and design and construction of the vector.
Prices: ES cells
Member: $328.26
Non member: $471.46
The price includes PCR screening of 3 ES cell plates for recombinants.
*Prices are valid for the 2012-2013 fiscal year