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Clinical Trials

Volunteer to Be Part of a Research Study

Page through all School of Medicine clinical and research trials below. There are two categories:

  • Detailed Trial Descriptions, submitted by researchers, includes trial specifics and contact information.

  • Additional Clinical Trials, which include basic study details. To contact the researcher either Google the PI (primary investigator) name or use our campus directory.

If you are a researcher seeking volunteers and your study is not posted, please
submit your Web ad here.
  

Detailed Trial Descriptions

 Results From Research and Clinical Trials : Selected site
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COMIRB Approved Advertisement TitleStudy GoalsEligibility CriteriaDate PostedCategory
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We are looking for Healthy Women to participate in a research study on.....Females, Aging, Metabolism, and Exercise (FAME)
To examine the role that female sex hormones play in metabolism, energy expenditure, physical activity and chronic disease.
Healthy women 40-60 who have regular menstrual cycles and using no hormonal contraceptives
7/27/2016 
Do you have Diabetes?
To find the best combination drug treatment for type 2 diabetes
Persons who have had diabetes for less than 5 years and metformin is the only diabetes medication you are taking.
7/27/2016 
Type 1 Diabetes Research Study
To study the effects of an FDA-approved medication on metabolism and blood vessel function.
Person 25-50 with type 1 diabetes who exercise vigorously less than four times per week and have normal blood pressure
7/27/2016 
CHILDHOOD and ADOLESCENT MIGRAINE PREVENTION STUDY
to test two medicines for migraine prevention in children and teens. We want to see if amitriptyline and/or topiramate are better than placebo (sugar pill) in reducing headache frequency.
Children 8-17 who have migraine headaches
7/27/2016 
Just received VARIVAX, the chickenpox vaccine?
Research study looking at the immune response to chickenpox vaccine
Age 12 months to 50 years; able to enroll in study within 10 days of vaccination.
7/27/2016 
Healthy Hispanic Female Needed
For brain imaging research study on how the brain works with we taste sweets. Your participation could help us to develop treatments and preventive measures for anorexia nervosa and obesity
Healthy females 22 to 29 who are right-handed, free of medication with no serious medical conditions, permanent metal implants or braces/retainers, and are at a healthy body weight.
7/27/2016 
Looking for HIV-positive individuals to participate in a research study on Lipodystrophy Syndrome
We are conducting a study of the relationship of bacteria in the gut to HIV infection. We are interested in finding out whether people who have metabolic diseases such as lipodystrophy (loss of fat tissue) as complications of long term antiretroviral therapy have a different makeup of their gut bacteria. We are therefore seeking volunteers with HIV infection to participate in a study of bacteria in the stool.
-Non-obese HIV positive individuals who are 18-65 years old -Either not currently on antiretroviral therapy (ART naïve or off therapy for 6 months or greater) or on effective ART with documented suppression for 6 months or greater. -We are particularly interested in enrolling subjects with lipodystrophy, but would also like to enroll individuals without lipodystrophy as controls.
7/27/2016 
Looking for HIV-positive and HIV-negative men to participate in a research study on smoking and lung disease
We are conducting a study to look at lung complications and disease in HIV/AIDS.
-Between 30 and 70 years old -Both HIV-positive and HIV-negative individuals with and without chronic obstructive pulmonary disease (COPD) -If HIV-positive, on a stable three-drug ART regimen with undetectable viral load for past 6 months
7/27/2016 
GENETIC-AF
The GENETIC-AF is a trial that will investigate the safety and effectiveness of an investigational drug on the recurrence of symptomatic atrial fibrillation in people who have heart failure. The investigational drug will be studied versus an approved drug after patients receive an electrical cardioversion.
Adults who have symptomatic atrial fibrillation may be eligible.
7/27/2016Heart and Blood Diseases
Healthy Volunteers Needed
To examine the differences in two subtypes of Parkinson Disease compared to health controls. This study involves an MRI.
- Between the ages of 50-80 - No metal in your body - In general good health
7/27/2016Nervous System Diseases
WISH - Women, insulin and sex hormones. Premenopausal women with type 1 diabetes needed for a research study.
This study plans to learn more about the menstrual cycle in women with Type 1 diabetes compared to the women who do not have diabetes. In addition, this research study plans to learn about the relationship between reproductive hormone levels and early signs of heart disease and hardening of the arteries in women with Type 1diabetes.
Age 18-45 Premenopausal Not using hormonal birth control and planning to stay off of them for at least 3 months. No currently pregnant or planning to become pregnant in the next 3 months. No recent history of amenorrhea (no menstrual period for at least 3 months) during the last 6 months. Menstrual cycle between 25-35 days on average. Normal thyroid function (can be treated) Normal kidney function (urinary albumin excretion rate
7/27/2016Heart and Blood Diseases
Interested in Weight Loss?
We are researching an investigational device for weight loss in overweight or obese subjects. The device is taken in pill form in two doses daily and may help decrease food intake.
*Are between 22 – 65 years old *Are overweight or obese (a BMI ≥27 and ≤40) - Check your BMI at http://www.nhlbisupport.com/bmi/ *Are willing to participate in regular study visits at the Anschutz Medical Campus
7/27/2016Nutritional and Metabolic Diseases
Do you need Emergency Contraception? Sexually Active Women needed for research.
We are interested in evaluating the progesterone intrauterine device (IUD) as a method of emergency contraception to prevent pregnancy after unprotected sex.
You might be eligible if you: - Are 18-45 years of age - Have had unprotected sex in the last 5 days - Have had a lapse in your birth control such as a missed pill, forgot your shot, condom broke, etc.
7/27/2016Urinary Tract, Sexual Organs, and Pregnancy Conditions
Information for patients. Living with diabetes is complicated.
The FREEDOM-3S Study is a clinical research study that will involve approximately 126 patients in the United States. It will look at a potential new treatment option, the ITCA 650,for people with type 2 diabetes. The ITCA 650 is a small metal cylinder (about the size of a matchstick) that is placed under the skin of the abdomen (belly) to slowly release the study medication – exenatide. The FREEDOM-3S Study is looking at how safe and well tolerated two different doses of the ITCA 650 are in people with type 2 diabetes who are already taking liraglutide (also known as Victoza injections, and metformin.
You may be eligible to take part if you: • are 18–80 years of age • have been diagnosed with type 2 diabetes for at least 3 months • have been taking liraglutide (Victoza) injections and metformin every day for at least 3 months.
7/27/2016Gland and Hormone Related Diseases
Controlling blood glucose levels. Can be a real balancing act.
The EASE-3 clinical research study is a study in which doctors hope to learn: • Whether the investigational medicine is safe to use in treating type 1 diabetes. • Whether adding the investigational medicine is more effective in controlling blood glucose than insulin alone.
You may be able to join this study if you: • Are 18 years of age or older and you have had insulin-dependent type 1 diabetes for at least a year. • Are willing to take a study medicine in addition to your insulin therapy. • Have an HbA1c level that falls within the range required by the study. • Have a good understanding of your disease and the ability to manage it and are willing to undergo study assessments.
7/27/2016Gland and Hormone Related Diseases
The Hot Flash Study
Our team is evaluating non-hormonal investigational medication, to see if it helps reduce the frequency and severity of hot flashes in post menopausal women ages 40 to 65
Have gone through menopause Are between the ages of 40 and 65 Are extremely bothered by frequent hot flashes Are willing to keep a record of your daily hot flashes (a handheld electronic diary similar to a smart phone will be provided to help you do this)
7/27/2016Urinary Tract, Sexual Organs, and Pregnancy Conditions
Do you have headaches?New
The University of Colorado is participating in a research study to determine if thoracic spine thrust manipulation alone is beneficial in the treatment of cervicogenic headaches. This project will see if this treatment can aid in reducing pain from these headaches.
You may be eligible to participate in this study if you answer yes to the following questions: - Do you have headaches that are mostly on one side which are associated with neck pain? - Are these headaches worse with movement or certain neck positions? - Do you have these headaches at least once a week for at least the last 2 months? - Are you between 18-60 years of age? - Can you come to physical therapy up to 6 times within a 30 day period? You may be ineligible to participate in this study if you have: - Rheumatoid arthritis - Osteoporosis - Broken bones in your neck or shoulder - A prolonged history of steroid use - A history of whiplash injury within the past six weeks
7/27/2016Muscle, Bone, and Cartilage Diseases
Healthy Volunteers Needed: Thinking and Memory in Parkinson's
This research study plans to better understand how changes in brain activity may be related to thinking problems in Parkinson's disease and to determine if stimulating certain areas the brain improves thinking and memory.
Healthy males over 50 with Parkinson's disease on stable doses of medication and have no metal in the body (dental work may be ok).
7/26/2016 
EFFECTS OF TESTOSTERONE THERAPY IN YOUNG ADOLESCENTS WITH KLINEFELTER SNDROME (47.XXY)
This study will study the effects of testosterone therapy on behavior, mood, problem solving, attention span, and motor skills in adolescent males with Klinefelter syndrome in early puberty. During this period in early puberty there is a lot of variability in how and when doctors start testosterone therapy. This study will evaluate if there are benefits to starting testosterone therapy in early puberty.
Participants with Klinefelter syndrome in early puberty (around age 10-15).
7/26/2016 
Volunteers with Alzheimer’s Disease Needed for Memory Study
To examine the safety and efficacy of the study drug, Sargramostim (Leukine®), on memory in adults with Mild-to-Moderate Alzheimer’s Disease.
1. Age 55 to 85 years; 2. Should have a mild-to-moderate Alzheimer's Disease diagnosis (Mini-Mental State Examination 10-26 inclusive); 3. If on anti-dementia treatment should be on stable treatment for at least 2 months (i.e. cholinesterase inhibitor and/or Memantine or Axona); 4. Stable on all other medications for at least 30 days prior to screen; 5. Should be fluent in English; 6. Should be physically able to participate by medical history, clinical exam and tests; 7. Should have a study partner to accompany them to scheduled visits.
7/26/2016 
T•A•C•I•T - Therapy After Cochlear Implants Using Telemedicine
This research plans to learn more about the use of telemedicine as a means of providing therapy to children who have a cochlear implant(s). While Auditory-Verbal Therapy has typically been delivered in person, many people are starting to access therapy over the internet. We are conducting this research to determine if the outcomes of therapy are the same when AVT is delivered in person and via telemedicine.
The TA•C•I•T team is looking for children ages 6 mos.-6 yrs. old who were implanted with cochlear implant(s) before age  3 ½..  Each child will spend nine months in both the in-person and telemedicine condition. The therapist will remain the same throughout the study. Total participation will last 18 months. The child will be tested three times: once when the study starts, and every nine months after that. A qualified study team member will administer speech, listening, and language tests to the child. They will also receive tests to identify how well their auditory area of the brain is developing.
7/26/2016 
Participants with Chronic Kidney Disease Needed for a Research Study about Phosphate
We are looking for men and women to participate in a research study examining whether lowering blood levels of phosphate will improve blood vessel function.
We need men and women who:  -are age 40-79 years old; women must be post-menopausal;  -have chronic kidney disease stage 3b or 4 (estimated GFR 15-45 ml/min);  -are not taking phosphate binders;  -do not have high blood phosphate (>5.5 mg/dL).
7/26/2016 
ESS-NSPAS Study
Bayer HealthCare is sponsoring a medical research study to look at the effectiveness of Essure after having a procedure (NovaSure) that decreases your heavy menstrual bleeding. Both Essure and NovaSure are approved by the FDA. This study is enrolling patients now and you may qualify to participate.
Are you currently using the Essure method of contraception? Are your periods heavy, frequent or prolonged? One important prerequisite is - you must have had a successful Essure placement AND be willing to undergo a NovaSure endometrial ablation, a treatment option for heavy menstrual bleeding (menorrhagia).
7/26/2016 
Volunteers Needed for Cardiovascular Research Study at the Division of Renal Diseases and Hypertension Clinical Research Unit
This research study will compare blood vessel function in healthy adults to adults with two different types of kidney disease. The testing visit will include non-invasive testing of blood vessel function and collection of blood and cells from an IV.  As a volunteer, you will receive the following information about your health: resting EKG; blood cholesterol screening,    blood sugar screening, blood pressure screening, and physical Exam.
We are looking for men and women, aged 18-80 years, non-smokers, generally healthy, and free from hypertension. Women must not be pregnant of trying to become pregnant
7/26/2016--Select a Category--
Volunteers are Invited for a Research Study Looking at Pain in Knee Osteoarthritis
- To better understand the complex experience of pain for people with knee osteoarthritis - This study will measure different aspects of pain perception and knee function in people with and without knee osteoarthritis
- Age 50-85 - NOT diagnosed with knee osteoarthritis - NO knee pain
7/26/2016Muscle, Bone, and Cartilage Diseases
Do you have insomnia or Use cannabis to help you sleep?
We are interested in learning more about the effects of cannabis use for insomnia and how it may or may not affect your sleep
Adults 21-80 years old cannabis use for sleep
7/26/2016--Select a Category--
Healthy Women Needed
This study plans to research how metabolic challenges of increased insulin and increased fats affect reproductive hormones.
In order to be eligible you must: Be a healthy woman age 18-38, have a BMI between 18 and 25, have regular menstrual cycles (25-35 days), not be currently using hormones (like birth control medication), not be pregnant or planning to become pregnant. In order to enroll all participants must meet specific criteria. The criteria listed above is only a partial list of all the requirements. Only a clinical research staff member can determine eligibility.
7/26/2016--Select a Category--
Are you interested in learning about how your breast milk helps your baby grow?
To find out how maternal size and diabetes status affect her breast milk To find out what unique parts of breast milk may affect how infants grow. To learn how to ensure infants receive the best nutrition possible
Women 20-35 who are at least 28 weeks into their pregnancy and planning on exclusively breastfeeding their infant for at least 4 months and delivering at University of Colorado Hospital.
7/25/2016 
Free Family Therapy for Youth with Mood Problems
Helping youth and their families understand and cope with mood swings, develop plans for preventing moods from getting worse, communicate more effectively and solve family problems
  • Youth between 9-17 who has recently had significant mood swings, has at least one parent with bipolar disorder and does not abuse alcohol or substances. 
  • Must agree not to participate in family therapy with another provider for the first year.
7/25/2016 
Genital Herpes?
This study will look at the body's immune response (how the body fights infection) to the onset of genital herpes.  1-2 study visits for blood draws over the course of 3 months.
  • 18+ years of age
  • Have developed an outbreak of genital herpes within the last 10 days.
7/25/2016 

​Additional Clinical Trails

 Results From Research : Selected site
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RANDOMIZED PHASE III COMPARISON OF STANDARD DOSE (60 GY) VS HIGH DOSE (74 GY) CONFORMAL RADIOTHERAPY WITH CONCURRENT AND CONSOLIDATION CARBOPLATIN/PACLITAXEL +/- CETUXIMAB IN PATIENTS WITH STAGE IIIA/IIIB NON SMALL CELL LUNG CANCER
Kavanagh, Brian D07-0851
NEW TRENDS IN HIV-RELATED RISKY PATTERNS OF INJECTING DRUG USE AND DRUGS DISTRIBUTION IN FOUR EURASIAN COUNTRIES WITH SUBSTANTIAL PRESENCE OF ATDS
Booth, Robert E08-1117
Helping Ourselves, Helping Others: The Young Womens' Breast Cancer Study
Borges, Virginia F. M.D.08-1222
S0931, "EVEREST: EVErolimus for Renal Cancer Ensuing Surgical Therapy, a Phase III Study"
Lam, Elaine Tat M.D.11-0545
GOG 9923 - A PHASE I STUDY OF INTRAVENOUS CARBOPLATIN/PACLITAXEL OR INTRAVENOUS AND INTRAPERITONEAL PACLITAXEL/CISPLATIN IN COMBINATION WITH CONTINUOUS OR INTERMITTENT / /CTEP SUPPLIED AGENT ABT-888 (NSC #737664) AND CTEP-SUPPLIED AGENT BEVACIZUMAB (NSC #704865) IN NEWLY DIAGNOSED PATIENTS WITH PREVIOUSLY UNTREATED EPITHELIAL OVARIAN, FALLOPIAN TUBE OR PRIMARY PERITONEAL CANCER
Guntupalli, Saketh Ram11-0636
A Phase II Study of the Aurora and Angiogenic Kinase Inhibitor ENMD-2076 in Previously Treated Locally Advanced and Metastatic Triple-Negative Breast Cancer
Diamond, Jennifer R M.D.11-0684
Identifying Unique Risks to Pregnancy In Perinatally Infected HIV Positive Women
Weinberg, Adriana11-1653
Oncofertility Patient Registry
Kondapalli, Laxmi A12-0389
An International Phase 3, Randomized Trial of Autologous Dendritic Cell Immunotherapy (AGS-003) Plus Standard Treatment of Advanced Renal Cell Carcinoma (ADAPT)
Lam, Elaine Tat M.D.13-1546
A phase II study of ponatinib in cohorts of patients with lung cancer preselected using different candidate predictive biomarkers.
Camidge, David Ross MD, PhD13-2002
A Phase 2B Randomized, Controlled, Multicenter, Open-Label Study of the Efficacy and Immune Response of GVAX Pancreas Vaccine (with Cyclophosphamide) and CRS-207 Compared to Chemotherapy or to CRS-207 Alone in Adults with Previously Treated Metastatic Pancreatic Adenocarcinoma
Weekes, Colin Dexter13-3144
Vascular mechanisms for the effects of loss of ovarian hormone function on cognition in women
Hildreth, Kerry L. MD14-0193
A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study Assessing the Effect of Gelesis100 on Body Weight in Overweight and Obese Subjects with and without Type 2 Diabetes. Sponsor Protocol No. G-04. WIRB Protocol No. 20150046
Hill, James O PhD14-0383
Reclaim Deep Brain Stimulation Therapy for Obsessive-Compulsive Disorder
Abosch, Aviva M.D.14-0554
A Phase I Trial of Inhaled Iloprost for the Prevention of Lung Cancer in Former Smokers
Miller, James York E M.D.14-1247
LIBERTY 360: Prospective, Observational, Multi-Center Clinical Study to Evaluate Acute & Long Term Clinical & Economic Outfomes of Endovascular Device Intervention in Patients with Distal Outflow Peripheral Arterial Disease (PAD)
Armstrong, Ehrin14-1522
Multicenter, open-label, randomized, controlled phase III clinical study of the efficacy and safety of photodynamic therapy using porfimer sodium for injection as treatment for unresectable advanced perihilar cholangiocarcinoma Sponsor Protocol No. PIN-PHO1201 WIRB Protocol No. 20140456
Shah, Raj Jay M.D.14-1650
Functional Avoidance Radiation Therapy for Lung Cancer Patients
Vinogradskiy, Yevgeniy14-1856
Self-reported usage patterns of opioid analgesic medications after surgery
Bartels, Karsten14-1938
Pilot study of a surgery and chemotherapy-only approach in the upfront therapy of children with WNT positive standard risk medulloblastoma
Dorris, Kathleen McCarthy O'Toole14-2097
Analysis of cataract surgery outcomes performed at the Children's Hospital Colorado from January 2005 through October 2014
Singh, Jasleen14-2183
A PHASE 3B RANDOMIZED STUDY OF LENALIDOMIDE (CC-5013) PLUS RITUXIMAB MAINTENANCE THERAPY FOLLOWED BY LENALIDOMIDE SINGLE-AGENT MAINTENACE VERSUS RITYUXIMAB MAINTENANCE IN SUBJECTS WITH RELAPSED/REFRACTORY FOLLICULAR, MARGINAL ZONE OR MANTLE CELL LYMPHOMA
Bowles, Daniel W14-2282
Protocol for the Evaluation of Dario™ BGMS Performance at Elevated Altitude. Sponsor Protocol No. CP-0003; WIRB Protocol No. 20142637
Garg, Satish K14-2330
Use of Ultrasonic Bone Scalpel in Adolescent Idiopathic Scoliosis - Randomized Clinical Trial
Garg, Sumeet15-0036
A DOUBLE-BLIND, PLACEBO-CONTROLLED RANDOMIZED TRIAL TO STUDY THE VIASKIN MILK EFFICACY AND SAFETY FOR TREATING IgE-MEDIATED COW’S MILK ALLERGY IN CHILDREN (MILES STUDY) Sponsor Protocol No. MILES WIRB Protocol No. 20141789
Fleischer, David Mark M.D.15-0140
ABT-414 Alone or ABT-414 Plus Temozolomide versus Lomustine or Temozolomide for Recurrent Glioblastoma; a Randomized Phase II Study of the EORTC Brain Sponsor Protocol No. MI4-483 WIRB Protocol No. 20142384
Damek, Denise Marie15-0164
A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of Rivipansel (GMI-1070) in the Treatment of Vaso-Occlusive Crisis in Hospitalized Subjects with Sickle Cell Disease
Hassell, Kathryn L M.D.15-0391
Predicting the Safety and Effectiveness of Inferior Vena Cava Filters (PRESERVE) Sponsor Protocol No. G140045 P WIRB Protocol No. 20150996
Rochon, Paul J M.D.15-0537
Reproductive and Sexual Health Issues in Young Women with CF: A Patient Survey
Sagel, Scott D MD, PhD15-0575
In-Clinic Feasibility Study to Observe the Closed Loop System. Sponsor Protocol No. CEP273/Z25. WIRB Protocol No. 20130443
Slover, Robert H. M.D.15-0684


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