|We are looking for Healthy Women to participate in a research study on.....Females, Aging, Metabolism, and Exercise (FAME)|
To examine the role that female sex hormones play in metabolism, energy expenditure, physical activity and chronic disease.
Healthy women 40-60 who have regular menstrual cycles and using no hormonal contraceptives
|Do you have Diabetes?|
To find the best combination drug treatment for type 2 diabetes
Persons who have had diabetes for less than 5 years and metformin is the only diabetes medication you are taking.
|Type 1 Diabetes Research Study|
To study the effects of an FDA-approved medication on metabolism and blood vessel function.
Person 25-50 with type 1 diabetes who exercise vigorously less than four times per week and have normal blood pressure
|CHILDHOOD and ADOLESCENT MIGRAINE PREVENTION STUDY|
to test two medicines for migraine prevention in children and teens. We want to see if amitriptyline and/or topiramate are better than placebo (sugar pill) in reducing headache frequency.
Children 8-17 who have migraine headaches
|Just received VARIVAX, the chickenpox vaccine?|
Research study looking at the immune response to chickenpox vaccine
Age 12 months to 50 years; able to enroll in study within 10 days of vaccination.
|Healthy Hispanic Female Needed|
For brain imaging research study on how the brain works with we taste sweets. Your participation could help us to develop treatments and preventive measures for anorexia nervosa and obesity
Healthy females 22 to 29 who are right-handed, free of medication with no serious medical conditions, permanent metal implants or braces/retainers, and are at a healthy body weight.
|Looking for HIV-positive individuals to participate in a research study on Lipodystrophy Syndrome|
We are conducting a study of the relationship of bacteria in the gut to HIV
infection. We are interested in finding out whether people who have
metabolic diseases such as lipodystrophy (loss of fat tissue) as complications of
long term antiretroviral therapy have a different makeup of their gut bacteria.
We are therefore seeking volunteers with HIV infection to participate in a study
of bacteria in the stool.
-Non-obese HIV positive individuals who are 18-65 years old
-Either not currently on antiretroviral therapy (ART naïve or off therapy for 6
months or greater) or on effective ART with documented suppression for 6
months or greater.
-We are particularly interested in enrolling subjects with lipodystrophy, but
would also like to enroll individuals without lipodystrophy as controls.
|Looking for HIV-positive and HIV-negative men to participate in a research study on smoking and lung disease|
We are conducting a study to look at lung complications and disease in
-Between 30 and 70 years old
-Both HIV-positive and HIV-negative individuals with and without chronic
obstructive pulmonary disease (COPD)
-If HIV-positive, on a stable three-drug ART regimen with undetectable viral
load for past 6 months
The GENETIC-AF is a trial that will investigate the safety and effectiveness of an investigational drug on the recurrence of symptomatic atrial fibrillation in people who have heart failure. The investigational drug will be studied versus an approved drug after patients receive an electrical cardioversion.
Adults who have symptomatic atrial fibrillation may be eligible.
|5/4/2016||Heart and Blood Diseases
|Healthy Volunteers Needed|
To examine the differences in two subtypes of Parkinson Disease compared to health controls. This study involves an MRI.
- Between the ages of 50-80
- No metal in your body
- In general good health
|5/4/2016||Nervous System Diseases
|WISH - Women, insulin and sex hormones. Premenopausal women with type 1 diabetes needed for a research study.|
This study plans to learn more about the menstrual cycle in women with Type 1 diabetes compared to the women who do not have diabetes. In addition, this research study plans to learn about the relationship between reproductive hormone levels and early signs of heart disease and hardening of the arteries in women with Type 1diabetes.
Not using hormonal birth control and planning to stay off of them for at least 3 months.
No currently pregnant or planning to become pregnant in the next 3 months.
No recent history of amenorrhea (no menstrual period for at least 3 months) during the last 6 months.
Menstrual cycle between 25-35 days on average.
Normal thyroid function (can be treated)
Normal kidney function (urinary albumin excretion rate
|5/4/2016||Heart and Blood Diseases
|Healthy Volunteers Needed: Thinking and Memory in Parkinson's|
This research study plans to better understand how changes in brain activity may be related to thinking problems in Parkinson's disease and to determine if stimulating certain areas the brain improves thinking and memory.
Healthy males over 50 with Parkinson's disease on stable doses of medication and have no metal in the body (dental work may be ok).
|EFFECTS OF TESTOSTERONE THERAPY IN YOUNG ADOLESCENTS WITH KLINEFELTER SNDROME (47.XXY)|
This study will study the effects of testosterone therapy on behavior, mood, problem solving, attention span, and motor skills in adolescent males with Klinefelter syndrome in early puberty. During this period in early puberty there is a lot of variability in how and when doctors start testosterone therapy. This study will evaluate if there are benefits to starting testosterone therapy in early puberty.
Participants with Klinefelter syndrome in early puberty (around age 10-15).
|Volunteers with Alzheimer’s Disease Needed for Memory Study|
To examine the safety and efficacy of the study drug, Sargramostim (Leukine®), on memory in adults with Mild-to-Moderate Alzheimer’s Disease.
1. Age 55 to 85 years;
2. Should have a mild-to-moderate Alzheimer's Disease diagnosis (Mini-Mental State Examination 10-26 inclusive);
3. If on anti-dementia treatment should be on stable treatment for at least 2 months (i.e. cholinesterase inhibitor and/or Memantine or Axona);
4. Stable on all other medications for at least 30 days prior to screen;
5. Should be fluent in English;
6. Should be physically able to participate by medical history, clinical exam and tests;
7. Should have a study partner to accompany them to scheduled visits.
|T•A•C•I•T - Therapy After Cochlear Implants Using Telemedicine |
This research plans to learn more about the use of telemedicine as a means of providing therapy to children who have a cochlear implant(s). While Auditory-Verbal Therapy has typically been delivered in person, many people are starting to access therapy over the internet. We are conducting this research to determine if the outcomes of therapy are the same when AVT is delivered in person and via telemedicine.
The T•A•C•I•T team is looking for children ages 6 mos.-6 yrs. old who were implanted with cochlear implant(s) before age 3 ½.. Each child will spend nine months in both the in-person and telemedicine condition. The therapist will remain the same throughout the study. Total participation will last 18 months. The child will be tested three times: once when the study starts, and every nine months after that. A qualified study team member will administer speech, listening, and language tests to the child. They will also receive tests to identify how well their auditory area of the brain is developing.
|Participants with Chronic Kidney Disease Needed for a Research Study about Phosphate|
We are looking for men and women to participate in a research study examining whether
lowering blood levels of phosphate will improve blood vessel function.
We need men and women who:
-are age 40-79 years old; women must be post-menopausal;
-have chronic kidney disease stage 3b or 4 (estimated GFR 15-45 ml/min);
-are not taking phosphate binders;
-do not have high blood phosphate (>5.5 mg/dL).
Bayer HealthCare is sponsoring a medical research study to look at the effectiveness of Essure after having a procedure (NovaSure) that decreases your heavy menstrual bleeding. Both Essure and NovaSure are approved by the FDA.
This study is enrolling patients now and you may qualify to participate.
Are you currently using the Essure method of contraception?
Are your periods heavy, frequent or prolonged?
One important prerequisite is - you must have had a successful Essure placement AND be willing to undergo a NovaSure endometrial ablation, a treatment option for heavy menstrual bleeding (menorrhagia).
|Volunteers Needed for Cardiovascular Research Study at the Division of Renal Diseases and Hypertension Clinical Research Unit|
This research study will compare blood vessel function in healthy adults to adults with two different types of kidney disease. The testing visit will include non-invasive testing of blood vessel function and collection of blood and cells from an IV. As a volunteer, you will receive the following information about your health:resting EKG; blood cholesterol screening,
blood sugar screening, blood pressure screening, and physical Exam.
We are looking for men and women, aged 18-80 years, non-smokers, generally healthy, and free from hypertension. Women must not be pregnant of trying to become pregnant
|5/3/2016||--Select a Category--
|Volunteers are Invited for a Research Study Looking at Pain in Knee Osteoarthritis|
- To better understand the complex experience of pain for people with knee osteoarthritis
- This study will measure different aspects of pain perception and knee function in people with and without knee osteoarthritis
- Age 50-85
- NOT diagnosed with knee osteoarthritis
- NO knee pain
|5/3/2016||Muscle, Bone, and Cartilage Diseases
|Do you have insomnia or Use cannabis to help you sleep?|
We are interested in learning more about the effects of cannabis use for insomnia and how it may or may not affect your sleep
Adults 21-80 years old
cannabis use for sleep
|5/3/2016||--Select a Category--
|Are you 16-45 years old and interested in participating in a research study?|
We are looking for healthy individuals to serve as healthy controls to learn about children and young adults with stroke.
We need control subjects who are:
-16-45 years old (currently we are seeking subjects aged 16-23 and 39-45 years old)
-Without history of neurological trauma or disease
-Willing to undergo brain MRI scan
Participation will require one visit to the Brain Imaging Center on the Anschutz Medical Campus, which will take about one hour. If requested, we can give you a free DVD copy of your MRI scan. For more information, please contact Amanda Kenny (Amanda.Kenny@ucdenver.edu
|5/3/2016||Nervous System Diseases
|Are you interested in learning about how your breast milk helps your baby grow?|
To find out how maternal size and diabetes status affect her breast milk
To find out what unique parts of breast milk may affect how infants grow.
To learn how to ensure infants receive the best nutrition possible
Women 20-35 who are at least 28 weeks into their pregnancy and planning on exclusively breastfeeding their infant for at least 4 months and delivering at University of Colorado Hospital.
|Free Family Therapy for Youth with Mood Problems|
Helping youth and their families understand and cope with mood swings, develop plans for preventing moods from getting worse, communicate more effectively and solve family problems
- Youth between 9-17 who has recently had significant mood swings, has at least one parent with bipolar disorder and does not abuse alcohol or substances.
- Must agree not to participate in family therapy with another provider for the first year.
This study will look at the body's immune response (how the body fights infection) to the onset of genital herpes. 1-2 study visits for blood draws over the course of 3 months.
- 18+ years of age
- Have developed an outbreak of genital herpes within the last 10 days.
|Healthy Males needed for a research study of drug levels in blood and hair.|
This study plans to learn more about how tenofovir and emtricitabine (Truvada) build up in cells in blood and hair. Participation will include two 12 week dosing periods separated by a 12 week washout period (total duration is 36 weeks). Eligible participants will be given the supply of medications for the study.
- Must be age 18 to 50 years
- Must own smartphone
- Subject has a minimum scalp hair length of 2 cm in the occipital region.
- Have a low risk for HIV-1 infection
|The Role of Gut Bacteria in the Development of Type 1 Diabetes.|
The goal of the research is to better understand the role bacteria that live in the intestine in the development of type 1 diabetes
- Patients diagnosed with type 1 diabetes in the last 6 months
- Subjects with islet autoantibodies
- Subjects who do not have islet antibodies and are first-degree relatives of patients with diabetes or subjects with islet antibodies
- 1-45 years of age
|Are you interested in participating in a research study to help us learn more about where the fat tissue in your body originates?|
To understand if some fat cells (adipocytes) may originally come from cells in the bone marrow. Understanding the origin of fat cells is important because it may help to determine the health of fat cells and why fat that is stored in some places of your body is more ‘unhealthy’ than other fat.
Men and women:
Between the ages of 18 and 75 years AND
Had an allogeneic hematopoietic stem cell transplant at least 6 months ago –OR–
Have chronic phase chronic myeloid leukemia.
|5/2/2016||Nutritional and Metabolic Diseases
|Are you interested in learning more about daily blood sugar changes in your child?|
The Endocrinology department at Children’s Hospital Colorado is looking for
children and young adults interested in learning about day-to-day blood sugar
The study involves a single visit where diabetes screening will be provided as
well as placement of a continuous sugar monitor to be worn for up to 7 days.
Age 10-25 years
BMI < 85%ile
|5/2/2016||Nutritional and Metabolic Diseases
|Are you looking for an alternative treatment for your insomnia?|
The purpose of this pilot study is to learn more about treatments for insomnia. Long-term use and dependence on controlled substance sleep medications (also known as “hypnotics”) is a common issue and is a less than ideal way to treat insomnia. Stopping the use of sleeping pills and trying other treatments for insomnia is difficult for many insomnia patients. Treatments combining supervised medication tapering (SMT), which is a gradual reduction of medication use, and cognitive behavioral insomnia therapy for insomnia (CBT-I), which is a form of talk therapy that helps a person learn to better handle behaviors, habits and thoughts that lead to sleeping problems., help some who wish to stop using sleep aids, but many individuals who complete these treatments do not give up their sleep aids altogether. This project will look at how to best help insomnia patients transitioning from using sleep aids to other treatment options for their insomnia.
• Adults 21 years of age and older who have chronic insomnia
• Current medication use for treatment of chronic insomnia (over one year)
• Desire to stop medication use
|5/2/2016||Behaviors and Mental Disorders
|Research Study Evaluating the Implementation of a Transdiagnostic Group Intervention for Children with Behavior Problems within a Pediatric Outpatient Setting|
Research study designed to learn more about a 10-week group therapy program that
might be helpful for children with behavior problems and their parents/legal
Inclusion criteria for child participants:
- Between 8-12 years old
- Have behavior problems or a behavior disorder, such as Oppositional Defiant
Disorder, Conduct Disorder, Attention-Deficit/Hyperactivity Disorder,
Intermittent Explosive Disorder, Disruptive Mood Dysregulation Disorder
- Able to read and complete English-language questionnaires
- Able to attend 10 consecutive weeks of 90-minute group therapy sessions at
Children’s Hospital Colorado
- Have at least one parent/legal guardian able to complete English-language
questionnaires and willing to participate in parent sessions.
Exclusion criteria for child participants:
- Intellectual disability
- Developmental disability or significant developmental delay
- Current suicidal ideation, homicidal ideation and/or self-harm behaviors
- Active substance use problems
- Current participation in psychological treatment or participation in
psychological therapy within the past year
- Do not have at least one parent/legal guardian willing to participate in the
|5/2/2016||Behaviors and Mental Disorders