|Participants with Chronic Kidney Disease and Vitamin D Deficiency Needed for a Research Study 11-0521|
This study will examine whether nutritional or active
vitamin D supplementation will improve blood vessel
Person 18-80 with chronic kidney disease stage 3B or 4 (estimated GFR 44-15 m;/min) with a vitamin D deficiency or insufficiency. Women must not be pregnant or breastfeeding.
|Trouble Sleeping? HS-2655|
Study the effects of two different study drugs, one or two non-drug interventions and/or a combination of both to treat insomnia.
Persons 21+ who have trouble falling or staying asleep at night.
|Give Us a Hand 12-1084|
To better understand Multiple Sclerosis in children and teens.
Between the ages of 3-20 AND have Multiple Sclerosis diagnosed before 18
Do not have MS
|Are you an African American with asthma? HS-2805|
We are studying why some African American people have trouble with their asthma despite taking asthma medications.
Children age 5-17 and non-smoking Adults age18 and older who have asthma symptoms despite asthma treatment • African American ancestry (have at least one African American grandparent)
Wechsler, MD, Michael
|Peanut and Tree-Nut Allergy Research Study 13-2102|
The purpose of this study is to determine how the body's immune system interacts with nuts and other foods to cause allergic reaction.
6-75 years of age. Have a diagnosis of peanut and/or tree-nut allergy made by either skin test or blood tests. Have no known peanut and/or tree-nut allergy.
|Research about the Effect of Carbamazepine medication on the Etonogestrel Contraceptive Implant (Implanon®/Nexplanon®) 14-0584|
Do you currently have a birth control implant (Implanon®/ Nexplanon®) and are interested in participating in a research study to better understand the effects of certain medication on the implant?
• Women ages 18-45 who have had a birth control implant 1 to 3 years • Do not take any medications that are known to effect liver enzymes • Be willing to abstain during the study period or use a secondary form of non-hormonal contraception • Have baseline systolic blood pressure
|Do you have human growth hormone (hGH) deficiency? 13-2629|
Primary: To demonstrate a clinical superiority of MOD-4023 over placebo in terms
of decrease in Fat Mass (FM) in adult subjects with Growth Hormone Deficiency
a. To determine the efficacy of MOD-4023 over placebo in other body
composition variables (such as lean body mass and waist-to-hip ratio)
b. To evaluate the safety and tolerability of MOD-4023 over placebo in adult
subjects with GHD
c. To determine the IGF-I and IGFBP-3 serum levels
Adult men and women aged 23 to 70 years of age diagnosed with either adult or childhood onset growth hormone deficiency (GHD).
|Are you a parent of a child with a developmental disability and willing to contribute to a research project to increase awareness and understanding? 14-1287|
The purpose of this study is to gain knowledge on the topic of everyday stressors that affect the lives of children with developmental disabilities, as well as their parents/caregivers
Are you a parent of a child with a developmental disability and willing to contribute to a research project to increase awareness and understanding?
- (303) 520-7346
|Healthy Female Adults Needed!!! 07-0816|
For brain imaging research study on how the brain works with we taste sweets. Your participation could help us to develop treatments and preventive measures for anorexia nervosa and obesity
Healthy females 22 to 29 who are right-handed, free of medication with no serious medical conditions, permanent metal implants or braces/retainers, and are at a healthy body weight.
|Do you have an egg allergy? HS-2764|
To see if taking Baked Egg Therapy vs. Oral Immunotherapy may help egg-allergic children tolerate eggs.
males and females 3 to 16 years old, with documented egg allergy, ability to make regular visits to National Jewish Health for up to 2 years.
|State of Slim Study Examining Soy 14-1666|
The CU Anschutz Health and Wellness Center is seeking volunteers for a new weight loss research study looking at the role of soy protein in weight loss and weight maintenance. The study will last approximately 12 months. Participants will participate in a 16-week State of Slim weight loss program at no charge and receive free soy products or monetary stipends to be used to purchase State of Slim-friendly protein products. Participants will receive DEXA body composition scans, lab work and wellness assessments at no charge.
Are between 18 – 55 years old
Are overweight or obese (a BMI ≥27 and ≤40) - Check your BMI at:
Are willing to participate in weekly group weight loss classes for 16 weeks and attend five study visits over a 12 month period at the Anschutz Medical Campus
Are not vegetarian
Are not taking medications for cholesterol
Are not diabetic
Hill Ph.D, James
|Randomized Trial to Prevent Vascular Events in HIV (REPRIEVE) 15-0023|
Pitavastatin is a statin that along with diet is used for the treatment of high cholesterol. It also lowers triglyceride levels in the blood. The main purpose of this clinical trial is to see if pitavastatin can prevent heart disease and heart disease related deaths in people with HIV infection who are taking HIV medications.
This study lasts about 6 years (21 visits) and you may be eligible if:
• You have HIV and are between the ages of 40 and 75.
• You have been on antiretroviral therapy (ART) for at least 6 months.
• You have a CD4+ cell count > 100.
• You have no history of cardiovascular disease
(history of heart attack or stroke, etc.).
• You are not currently using a statin drug.
Campbell, MD, Thomas
|We are looking for Healthy Men and Women to participate in a research study to determine how Exercise Impacts Fat Metabolism During Sleep 13-0359|
The University of Colorado Anschutz Medical Campus is recruiting healthy men and women to participate in a research study investigating how exercise performed during the day impacts hormones and metabolism during sleep. Adults spend about one-third of their lives sleeping yet little is known about metabolism during this period or how day time exercise influences sleeping metabolism. Learning more about sleeping metabolism will improve our understanding of how the body regulates body weight.
This research study is looking for healthy men and women aged 20 to 35 years, who have a BMI < 30, exercise less than 3 days per week, and have a regular sleep schedule.
|Are you Interested in Being in a Weight Loss Research Study? 13-1550|
Volunteers needed for a research study to determine the best time to begin exercise within a lifestyle weight loss program.
• Be a man or woman between 18 and 55 years old
• Be generally healthy without diabetes or heart disease
• Be a non-smoker
• Not currently exercising regularly
• Have a BMI between 28 and 40 kg/m2
In order to enroll all participants must meet specific criteria. The criteria listed above is only a partial list of all the requirements to participate in this research study. Only a clinical research staff member can determine eligibility.
|Are you thinking about getting an IUD? 15-0413|
The University of Colorado School of Medicine’s Department of OB/GYN is seeking volunteers for a research study of a new copper intrauterine device.
Eligible participants must:
• Be generally healthy
• Be interested in using an IUD
• Be 18-40 years old
• Have regular menstrual cycles
|Investigations in Gestational Origins of Lifetime Development: Understanding health begins before birth. Are you in your first trimester of Pregnancy? 07-0535|
To learn more about how your metabolism is connected to your baby's growth and development
- Healthy Women ages 18-35 who are 10-14 weeks pregnant with single baby. With a BMI of 30-38 who are willing to complete 5 visits during pregnancy and agreeable to an infant blood draw at birth and DXA postpartum.
There is an option to take part in a 1 year follow-up which entails an additional 4 visits and another DXA at 1 year of life.
|We are Currently Enrolling People with Down syndrome for a study in Dr. Pelak's Brain and Vision Research lab at the University of Colorado Anschutz Medical Campus. 05-1131|
To examine visual brain function in people with mild memory impairments to detect early signs of Alzheimer's Disease.
Persons 19-30 who have Down Syndrome
|EMERALD STUDY: Effects of MEtformin on CardiovasculaR function in AdoLescents with Type 1 Diabetes 12-1528|
To determine the effects of Metformin on Cardiovascular Function in Adolescents with Type 1 Diabetes.
- Persons 12-21 who have Type 1 Diabetes
- Non-smoker, able to ride a stationary bike
- You must be willing to take metformin or placebo (sugar pill) for 3 months.
- Other exclusions apply, please contract study for more information
- 720-777-5774 or 720-777-6143
|Children's Hospital, department of Pediatric Neurology is conducting a research study 13-0032|
Evaluating the effects of a single treatment of injected BOTOX® (Botulinum Toxin Type A) for chronic migraine(s) in adolescents.
- Adolescents 12-17 who have no serious medical conditions but have at least 15 headaches a month for the last 6 months.
- You not have any previous BOTX treatments or are not currently using any prophylactic medicine.
|Non-Alcoholic Fatty Liver Disease and Obstructive Sleep Apnea: Mechanistic Links between Hypoxemia and Liver Injury 09-0169|
To learn if obstructive sleep apnea and low oxygen levels have a role in developing Non-Alcoholic Fatty Liver Disease (NAFLD).
Children 10-17 who have a normal weight and no serious medical problems
|Exercise and Cancer Prevention Research Study 13-2314|
The goal of this study is to better understand the biological mechanisms associated with exercise and reduced risk for breast cancer.
- You must be a female between the ages of 30-45 to participate in this study.
- You must be planning to live in the Denver metropolitan area for the next 10 consecutive months.
- You should not be a regular exerciser because this study is for people who do not exercise right now; however, you should be willing to participate in an exercise program 4 times per week for 16-weeks.
|Are you interested in a supervised exercise intervention? 13-3252|
Volunteers are needed for a research study to examine the effects of exercise
on food intake and appetite regulation.
- 21-45 years old
- Non- smoker
- Non- Diabetic
- Exercise no more than 1 time a week
- Maintained your current weight for last 6 months
- Have a body mass index (BMI) of 27-35
(check it out at http://nhlbisupport.com/bmi/)
|Study of Mood Disorder in Preschool Children 07-0932|
We are doing a research study to better understand what mood disorders look like in preschool children.
We are looking for volunteers who:
- Are parents of children between the ages of 4 and 6 years 0 months.
- Are in one of three groups:
- Their child has no major mental health problems, and there is no family history of major mood or psychotic disorders.
- Their child has been diagnosed with a mood disorder, bipolar disorder, or mood dysregulation disorder.
- Their child has been diagnosed with attention deficit hyperactivity disorder (ADHD).
- Parents or guardians will be asked to:
- Read and sign a consent form
- Participate in interviews about their children
- The children will be asked to:
How much time will this take?
- Participate in a story game
- Take tests of verbal and nonverbal abilities
The visit for the child will last from 1 to 2 hours. The visit for the parents will last 3 to 5 hours.
|Understanding how Tysabri and Gilenya Influence the Quality of your Daily Life with Multiple Sclerosis 13-2767|
The purpose of this research study is to compare two medications, Tysabri and Gilenya, used in the treatment of multiple sclerosis (MS), through a few self reported patient surveys. We will ask you to complete online surveys about overall health-related quality of life, disability, fatigue, cognition and productivity. We will also want to review your medical records to understand your MS history with your permission. This study will help us understand how these drugs are impacting each aspect of your daily lives.
- Between ages 16 and 65
- Scheduled to start natalizumab or fingolimod for the first time to treat your MS
|Living with MS? 12-1522|
To evaluate the safety of a new investigational drug that may help reduce relapses.
- Between the ages of 18 to 65
- Participants must have relapsing-remitting multiple sclerosis (RRMS)
|High Altitude Research Study 14-1514|
Subjects needed for a study on how high altitude affects cognitive performance
Male and Female subjects needed that are:
- Between the ages of 18-45 years old and exercise regularly
- Healthy: non smokers and not on medications
- Willing to stay below 7,000 ft for 3 weeks prior to altitude chamber day
|Are you Pregnant or a Nursing Mother? Consider being a part f a Breast Cancer Research. 12-0769|
This study will examine changes that occur in the breast tissue, blood and urine of a
woman after she has given birth to a child. The study will examine how a woman’s
breast and her cells change after pregnancy and breast feeding and how her immune
system interacts with these changes. The immune system is a complex network of cells
that identify our tissues as “self” or “foreign” as well as normal cells or cancer cells.
We hope to discover how a woman’s breast changes after pregnancy or breast feeding
to see if this time point in a woman’s life could be targeted to prevent breast cancer.
You are being asked to be in this research study because you are pregnant or were
recently pregnant and have not had breast cancer or another autoimmune disease.
|MRI and Questionnaire Research Study for Patients with MS Taking Tysabri and Healthy Controls 13-2927|
This research study plans to learn more about the differences in brain scans and self-reported quality of life between MS patients taking natalizumab (Tysabri) and individuals without MS.
You may qualify for this research study of you are:
A Relapsing Multiple Sclerosis patient 18-55 years old who has been taking Tysabri (natalizumab) for at least 2 years
A healthy individuals 18-55 years old without MS or other neurological conditions
|Do You have type 1 diabetes? 14-2423|
To learn more about an investigation study drug
- Persons 18 to 30 years who have had Type 1 Diabetes for ≥12 months
- Have a stable insulin treatment (MDI or pump) ≥3 months and an A1C ≥9.0
- Not using an antidiabetic agent other than insulin or insulin analogue
- Willing to take study drug or placebo pills daily for 3 months
- Not pregnant, breast-feeding or intending to become pregnant
- Other inclusion/exclusions apply, please contact study coordinator for more information
Paul R, Wadwa
|Will You Be a Caregiver For Your Loved One During Transplant? 13-2639|
We are conducting a research study to assess treatments to reduce the effects of stress on caregivers of patients experiencing an allogeneic transplant.
Patient inclusion criteria include: 1) receiving an allogeneic HSCT, 2) able to read and speak English, 3) telephone access.
Caregiver inclusion criteria include: 1) the person in the patient's life who is primarily responsible for care decisions, emotionally invested in the patient's care, provides instrumental care such as transportation, and available if randomized to the fPER group to participate in the majority of intervention sessions, 2) able to read and speak English, 3) willingness to use a Smartphone, 4) absence of a serious medical condition likely to influence hair cortisol, 5) no steroid medications, and 6) over the age of 18 years.