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Clinical Trials

Volunteer to Be Part of a Research Study

Page through all School of Medicine clinical and research trials below. There are two categories:

  • Detailed Trial Descriptions, submitted by researchers, includes trial specifics and contact information.

  • Additional Clinical Trials, which include basic study details. To contact the researcher either Google the PI (primary investigator) name or use our campus directory.

If you are a researcher seeking volunteers and your study is not posted, please
submit your Web ad here.

Detailed Trial Descriptions

 Results From Research and Clinical Trials : Selected site
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TitleStudy GoalsEligibility CriteriaContact Information
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Participants with Chronic Kidney Disease and Vitamin D Deficiency Needed for a Research Study 11-0521
This study will examine whether nutritional or active vitamin D supplementation will improve blood vessel function​.
Person 18-80 with chronic kidney disease stage 3B or 4 (estimated GFR 44-15 m;/min) with a vitamin D deficiency or insufficiency.  Women must not be pregnant or breastfeeding.
PI: Kendrick, Jessica
  • 303-724-2275
Trouble Sleeping? HS-2655
Study the effects of two different study drugs, one or two non-drug interventions and/or a combination of both to treat insomnia.
Persons 21+ who have trouble falling or staying asleep at night.
PI: Edinger, Jack
  • 303-398-1938
Give Us a Hand 12-1084
To better understand Multiple Sclerosis in children and teens.
Between the ages of 3-20 AND have Multiple Sclerosis diagnosed before 18 OR Do not have MS
PI: Schreiner, Teri
  • 303-724-3635
Are you an African American with asthma? HS-2805
 We are studying why some African American people have trouble with their asthma despite taking asthma medications.
 Children age 5-17 and non-smoking Adults age18 and older who have asthma symptoms despite asthma treatment • African American ancestry (have at least one    African American grandparent)
PI: Wechsler, MD, Michael
  • 303-398-1443
Peanut and Tree-Nut Allergy Research Study 13-2102
The purpose of this study is to determine how the body's immune system interacts with nuts and other foods to cause allergic reaction.
6-75 years of age. Have a diagnosis of peanut and/or tree-nut allergy made by either skin test or blood tests. Have no known peanut and/or tree-nut allergy.
PI: Dreskin, Stephen
  • 303-724-7193
Research about the Effect of Carbamazepine medication on the Etonogestrel Contraceptive Implant (Implanon®/Nexplanon®) 14-0584
Do you currently have a birth control implant (Implanon®/ Nexplanon®) and are interested in participating in a research study to better understand the effects of certain medication on the implant?
Women ages 18-45 who have had a birth control implant 1 to 3 years • Do not take any medications that are known to effect liver enzymes • Be willing to abstain during the study period or use a secondary form of non-hormonal contraception • Have baseline systolic blood pressure
PI: Lazorwitz, Aaron
  • 303-724-8482
Do you have human growth hormone (hGH) deficiency? 13-2629
Primary: To demonstrate a clinical superiority of MOD-4023 over placebo in terms of decrease in Fat Mass (FM) in adult subjects with Growth Hormone Deficiency Secondary a. To determine the efficacy of MOD-4023 over placebo in other body composition variables (such as lean body mass and waist-to-hip ratio) b. To evaluate the safety and tolerability of MOD-4023 over placebo in adult subjects with GHD c. To determine the IGF-I and IGFBP-3 serum levels
Adult men and women aged 23 to 70 years of age diagnosed with either adult or childhood onset growth hormone deficiency (GHD).
PI: Wierman, Margaret
  • 720-848-7710
Are you a parent of a child with a developmental disability and willing to contribute to a research project to increase awareness and understanding? 14-1287
The purpose of this study is to gain knowledge on the topic of everyday stressors that affect the lives of children with developmental disabilities, as well as their parents/caregivers
Are you a parent of a child with a developmental disability and willing to contribute to a research project to increase awareness and understanding?
PI: Benson, Brenna
  • (303) 520-7346
Healthy Female Adults Needed!!! 07-0816
For brain imaging research study on how the brain works with we taste sweets. Your participation could help us to develop treatments and preventive measures for anorexia nervosa and obesity
Healthy females 22 to 29 who are right-handed, free of medication with no serious medical conditions, permanent metal implants or braces/retainers, and are at a healthy body weight.
PI: Frank, Guido
  • 720-777-4026
Do you have an egg allergy? HS-2764
To see if taking Baked Egg Therapy vs. Oral Immunotherapy may help egg-allergic children tolerate eggs.
males and females 3 to 16 years old, with documented egg allergy, ability to make regular visits to National Jewish Health for up to 2 years.
PI: Leung, Donald
  • 303-398-1618
State of Slim Study Examining Soy 14-1666
The CU Anschutz Health and Wellness Center is seeking volunteers for a new weight loss research study looking at the role of soy protein in weight loss and weight maintenance. The study will last approximately 12 months. Participants will participate in a 16-week State of Slim weight loss program at no charge and receive free soy products or monetary stipends to be used to purchase State of Slim-friendly protein products. Participants will receive DEXA body composition scans, lab work and wellness assessments at no charge.
Are between 18 – 55 years old Are overweight or obese (a BMI ≥27 and ≤40) - Check your BMI at: Are willing to participate in weekly group weight loss classes for 16 weeks and attend five study visits over a 12 month period at the Anschutz Medical Campus Are not vegetarian Are not taking medications for cholesterol Are not diabetic
PI: Hill Ph.D, James
  • 303-724-9198
Randomized Trial to Prevent Vascular Events in HIV (REPRIEVE) 15-0023
Pitavastatin is a statin that along with diet is used for the treatment of high cholesterol. It also lowers triglyceride levels in the blood. The main purpose of this clinical trial is to see if pitavastatin can prevent heart disease and heart disease related deaths in people with HIV infection who are taking HIV medications.
This study lasts about 6 years (21 visits) and you may be eligible if: • You have HIV and are between the ages of 40 and 75. • You have been on antiretroviral therapy (ART) for at least 6 months. • You have a CD4+ cell count > 100. • You have no history of cardiovascular disease (history of heart attack or stroke, etc.). • You are not currently using a statin drug.
PI: Campbell, MD, Thomas
  • 303-724-0712
We are looking for Healthy Men and Women to participate in a research study to determine how Exercise Impacts Fat Metabolism During Sleep 13-0359
The University of Colorado Anschutz Medical Campus is recruiting healthy men and women to participate in a research study investigating how exercise performed during the day impacts hormones and metabolism during sleep.  Adults spend about one-third of their lives sleeping yet little is known about metabolism during this period or how day time exercise influences sleeping metabolism.  Learning more about sleeping metabolism will improve our understanding of how the body regulates body weight.
This research study is looking for healthy men and women aged 20 to 35 years, who have a BMI < 30, exercise less than 3 days per week, and have a regular sleep schedule.
PI: Rynders, Corey
  • 720-848-6461
Are you Interested in Being in a Weight Loss Research Study? 13-1550
Volunteers needed for a research study to determine the best time to begin exercise within a lifestyle weight loss program.
• Be a man or woman between 18 and 55 years old • Be generally healthy without diabetes or heart disease • Be a non-smoker • Not currently exercising regularly • Have a BMI between 28 and 40 kg/m2 In order to enroll all participants must meet specific criteria. The criteria listed above is only a partial list of all the requirements to participate in this research study. Only a clinical research staff member can determine eligibility.
PI: Catenacci, Victoria
  • 303-724-9098
Are you thinking about getting an IUD? 15-0413
The University of Colorado School of Medicine’s Department of OB/GYN is seeking volunteers for a research study of a new copper intrauterine device.
Eligible participants must: • Be generally healthy • Be interested in using an IUD • Be 18-40 years old • Have regular menstrual cycles
PI: Teal, Stephanie
  • 303-724-5284
Investigations in Gestational Origins of Lifetime Development: Understanding health begins before birth. Are you in your first trimester of Pregnancy? 07-0535
To learn more about how your metabolism is connected to your baby's growth and development
  • Healthy Women ages 18-35 who are 10-14 weeks pregnant with single baby.  With a  BMI of 30-38 who are willing to complete 5 visits during pregnancy and agreeable to an infant blood draw at birth and DXA postpartum.  
There is an option to take part in a 1 year follow-up which entails an additional 4 visits and another DXA at 1 year of life.
PI: Barbour, Linda
  • 303-724-3974
We are Currently Enrolling People with Down syndrome for a study in Dr. Pelak's Brain and Vision Research lab at the University of Colorado Anschutz Medical Campus. 05-1131
To examine visual brain function in people with mild memory impairments to detect early signs of Alzheimer's Disease.​
Persons 19-30 who have Down Syndrome
PI: Pelak, Victoria
  • 303-724-2184
EMERALD STUDY: Effects of MEtformin on CardiovasculaR function in AdoLescents with Type 1 Diabetes 12-1528
​To determine the effects of Metformin on Cardiovascular Function in Adolescents with Type 1 Diabetes.
  • Persons 12-21 who have Type 1 Diabetes
  • Non-smoker, able to ride a stationary bike
  • You must be willing to take metformin or placebo (sugar pill) for 3 months.
  • Other exclusions apply, please contract study for more information
PI: Nadeau, Kristen
  • 720-777-5774 or 720-777-6143
Children's Hospital, department of Pediatric Neurology is conducting a research study 13-0032
Evaluating the effects of a single treatment of injected BOTOX® (Botulinum Toxin Type A) for chronic migraine(s) in adolescents.
  • Adolescents 12-17 who have no serious medical conditions but have at least 15 headaches a month for the last 6 months. 
  • You not have any previous BOTX treatments or are not currently using any prophylactic medicine.
PI: Kedia, Sita
  • 720-777-8588
Non-Alcoholic Fatty Liver Disease and Obstructive Sleep Apnea: Mechanistic Links between Hypoxemia and Liver Injury 09-0169
To learn if obstructive sleep apnea and low oxygen levels have a role in developing Non-Alcoholic Fatty Liver Disease (NAFLD).​​​
Children 10-17 who have a normal weight and no serious medical problems
PI: Sundaram, Shikha
  • 720-777-3819
Exercise and Cancer Prevention Research Study 13-2314
The goal of this study is to better understand the biological mechanisms associated with exercise and reduced risk for breast cancer.
  • You must be a female between the ages of 30-45 to participate in this study. 
  • You must be planning to live in the Denver metropolitan area for the next 10 consecutive months. 
  • You should not be a regular exerciser because this study is for people who do not exercise right now; however, you should be willing to participate in an exercise program 4 times per week for 16-weeks.
PI: Bryan, Angela
  • 303-492-9549
Are you interested in a supervised exercise intervention? 13-3252
Volunteers are needed for a research study to examine the effects of exercise on food intake and appetite regulation.
  • 21-45 years old
  • Non- smoker
  • Non- Diabetic
  • Exercise no more than 1 time a week
  • Maintained your current weight for last 6 months
  • Have a body mass index (BMI) of 27-35 (check it out at
PI: Cornier, Marc
  • 303-724-9024
Study of Mood Disorder in Preschool Children 07-0932
We are doing a research study to better understand what mood disorders look like in preschool children.
We are looking for volunteers who:  
  • Are parents of children between the ages of 4 and 6 years 0 months.
  • Are in one of three groups:
    1. Their child has no major mental health problems, and there is no family history of major mood or psychotic disorders.
    2. Their child has been diagnosed with a mood disorder, bipolar disorder, or mood dysregulation disorder. 
    3. Their child has been diagnosed with attention deficit hyperactivity  disorder (ADHD).  
  • Parents or guardians will be asked to:
    • Read and sign a consent form
    • Participate in interviews about their children
  • The  children will be asked to:
    • Participate in a story game
    • Take tests of verbal and nonverbal abilities
How much time will this take?
The visit for the child will last from 1 to 2 hours.  The visit for the parents will last 3 to 5 hours.
PI: Ross, Randy
  • 303-724-6200
Understanding how Tysabri and Gilenya Influence the Quality of your Daily Life with Multiple Sclerosis 13-2767
The purpose of this research study is to compare two medications, Tysabri and Gilenya, used in the treatment of multiple sclerosis (MS), through a few self reported patient surveys. We will ask you to complete online surveys about overall health-related quality of life, disability, fatigue, cognition and productivity. We will also want to review your medical records to understand your MS history with your permission. This study will help us understand how these drugs are impacting each aspect of your daily lives.
  • Between ages 16 and 65
  • Scheduled to start natalizumab or fingolimod for the first time to treat your MS
PI: Nair, Kavita
  • 303-724-8388
Living with MS? 12-1522
To evaluate the safety of a new investigational drug that may help reduce relapses.
  • Between the ages of 18 to 65
  • Participants must have relapsing-remitting multiple sclerosis (RRMS)
PI: Corboy, John
  • 303-724-7421
High Altitude Research Study 14-1514
Subjects needed for a study on how high altitude affects cognitive performance
Male and Female subjects needed that are:
  • Between the ages of 18-45 years old and exercise regularly
  • Healthy: non smokers and not on medications
  • Willing to stay below 7,000 ft for 3 weeks prior to altitude chamber day
PI: Roach, Robert
  • 303-724-1674
Are you Pregnant or a Nursing Mother? Consider being a part f a Breast Cancer Research. 12-0769
This study will examine changes that occur in the breast tissue, blood and urine of a woman after she has given birth to a child. The study will examine how a woman’s breast and her cells change after pregnancy and breast feeding and how her immune system interacts with these changes. The immune system is a complex network of cells that identify our tissues as “self” or “foreign” as well as normal cells or cancer cells. We hope to discover how a woman’s breast changes after pregnancy or breast feeding to see if this time point in a woman’s life could be targeted to prevent breast cancer.
You are being asked to be in this research study because you are pregnant or were recently pregnant and have not had breast cancer or another autoimmune disease.
PI: Borges, Virginia
  • 303-724-6077
MRI and Questionnaire Research Study for Patients with MS Taking Tysabri and Healthy Controls 13-2927
This research study plans to learn more about the differences in brain scans and self-reported quality of life between MS patients taking natalizumab (Tysabri) and individuals without MS.
You may qualify for this research study of you are: A Relapsing Multiple Sclerosis patient 18-55 years old who has been taking Tysabri (natalizumab) for at least 2 years OR A healthy individuals 18-55 years old without MS or other neurological conditions
PI: Miravalle, Augusto
  • 303-724-8388
Do You have type 1 diabetes? 14-2423
To learn more about an investigation study drug
    • Persons 18 to 30 years who have had Type 1 Diabetes for 12 months
    • Have a stable insulin treatment (MDI or pump) 3 months and an A1C 9.0
    • Not using an antidiabetic agent other than insulin or insulin analogue
    • Willing to take study drug or placebo pills daily for 3 months
    • Not pregnant, breast-feeding or intending to become pregnant
    • Other inclusion/exclusions apply, please contact study coordinator for more information
PI: Paul R, Wadwa
  • 303-724-9267
Will You Be a Caregiver For Your Loved One During Transplant? 13-2639
We are conducting a research study to assess treatments to reduce the effects of stress on caregivers of patients experiencing an allogeneic transplant.
Patient inclusion criteria include: 1) receiving an allogeneic HSCT, 2) able to read and speak English, 3) telephone access. Caregiver inclusion criteria include: 1) the person in the patient's life who is primarily responsible for care decisions, emotionally invested in the patient's care, provides instrumental care such as transportation, and available if randomized to the fPER group to participate in the majority of intervention sessions, 2) able to read and speak English, 3) willingness to use a Smartphone, 4) absence of a serious medical condition likely to influence hair cortisol, 5) no steroid medications, and 6) over the age of 18 years.
PI: Laudenslager, Mark
  • 303-724-9279

​Additional Clinical Trails

 Results From Research : Selected site
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Protocol TitlePI NameInstitution Number
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A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study Assessing the Effect of Gelesis100 on Body Weight in Overweight and Obese Subjects with and without Type 2 Diabetes. Sponsor Protocol No. G-04. WIRB Protocol No. 20150046
Hill, James14-0383
A Randomized Phase 3 Open Label Study of Nivolumab versus Bevacizumab and a Safety Study of Nivolumab or Nivolumab in Combination with Ipilimumab in Adult Subjects with Recurrent Glioblastoma (GBM)(CheckMate 143: CHECKpoint pathway and nivoluMAb clinical Trial Evaluation 143). Sponsor Protocol No. CA209143. WIRB Protocol No. 20140894
Damek, Denise14-0518
A Phase 3 Randomized, Placebo-Controlled Trial of Carboplatin and Paclitaxel With or Without the PARP Inhibitor Veliparib (ABT-888) in HER2-Negative Metastatic or Locally Advanced Unresectable BRCA-Associated Breast Cancer Sponsor Protocol No. M12-914 WIRB Protocol No. 20141072
Borges, Virginia14-0799
PROspective Study of the IMPACT of Decipher® Prostate Cancer Classifier on Physician and Patient Treatment Consideration and Decisions following Radical Prostatectomy [PRO-IMPACT] Sponsor Protocol No. CU004 WIRB Protocol No. 20142208
Maroni, Paul14-0910
A Double-masked, Placebo-controlled Study with Open-Label Period to Evaluate the Efficacy and Safety of MEDI-551 in Adult Subjects with Neuromyelitis Optica and Neuromyelitis Optica Spectrum Disorders Sponsor Protocol No. CD-IA-MEDI-551-1155 WIRB Protocol No. 20142285
Bennett, Jeffrey14-0926
CEP292- A Performance Evaluation of the Enlite 3 Sensor to Support a Full 168 hours (7days) of Use. Sponsor Protocol No. CEP292/Z25/B. WIRB Protocol No. 20140632
Slover, Robert14-1039
Menard-Katcher, Paul14-1285
A Phase 4 Multicenter, Open-Label, Single Arm Study to Evaluate Switching from BRACET/Gilenya® to Natalizumab in Subjects with Relapsing Forms of Multiple Sclerosis (MS). Sponsor Protocol No. 101MS409. WIRB Protocol No. 20141062
Alvarez, Enrique14-1295
A Clinical Outcomes Study to Compare the Incidence of Major Adverse Cardiovascular Events in Subjects Presenting with Acute Coronary Syndrome Treated with Losmapimod Compared to Placebo. Sponsor Protocol No. PM1116197. WIRB Protocol No. 20141040
Krantz, Mori14-1331
A Double-Blind, Placebo-Controlled, Randomized-Withdrawal, Multicenter Study of the Efficacy and Safety of Xyrem with an Open- Label Pharmacokinetic Evaluation and Safety Extension in Pediatric Subjects with Narcolepsy with Cataplexy Sponsor Protocol No. 13-005 WIRB Protocol No. 20141141
Halbower, Ann14-1333
A Randomized, Double-blind, Placebo-controlled, Ascending Multiple-Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AMG 282 in Healthy Subjects and Subjects with Chronic Rhinosinusitis with Nasal Polyps. Sponsor Protocol No. 20110236. WIRB Protocol No. 20150667
Kingdom, Todd14-1371
An Open-label, Non-randomised, Multicentre, Comparative, Phase I Study to Determine the Pharmacokinetics, Safety and Tolerability of AZD9291 following a Single Oral Dose to Patients with Advanced Solid Tumours and Normal Hepatic Function or Mild or Moderate Hepatic Impairment Sponsor Protocol No. D5160C00008 WIRB Protocol No. 20142209
O'Bryant, Cindy14-1390
Fleischer, David14-1399
BOTOX® Treatment in Pediatric Lower Limb Spasticity: Double-blind Study Sponsor Protocol No. 191622-111 WIRB Protocol No. 20132162
Biffl, Susan14-1404
BOTOX® Treatment in Pediatric Lower Limb Spasticity: Open-label Study Protocol No. 191622-112 WIRB Protocol No. 20132135
Biffl, Susan14-1405
An Open-Label Study to Evaluate the Safety, Efficacy and Pharmacokinetics of Ombitasvir/ ABT-450/Ritonavir (Ombitasvir/ABT-450/r) and Dasabuvir Co-administered with Sofosbuvir (SOF) With and Without Ribavirin (RBV) in Direct-Acting Antiviral Agent (DAA) Treatment-Experienced Adults With Genotype 1 Chronic Hepatitis C Virus (HCV) Infection. Sponsor Protocol No. M14-224. WIRB Protocol No. 20142269
Everson, Greg14-1435
A 6-month safety and benefit study of inhaled fluticasone propionate/salmeterol combination versus inhaled fluticasone propionate in the treatment of 6,200 pediatric subjects 4-11 years old with persistent asthma. Sponsor Protocol No. SAS115358. WIRB Protocol No. 20111924
Anderson, William14-1445
Gutman, Jonathan14-1455
A Phase II Randomized, Double-Blind, Placebo-Controlled Trial of Radium-223 Dichloride Versus Placebo When Administered to Metastatic HER2 Negative Hormone Receptor Positive Breast Cancer Subjects with Bone Metastases Treated with Hormonal Treatment Background Therapy Sponsor Protocol No. BAY 88-8223 / 16298 WIRB Protocol No. 20150791
Fisher, Christine14-1465
Phase I, Open-Label, Dose-Escalation Study of the Safety and Pharmacokinetics of MOXR0916 Administered Intravenously as a Single Agent to Patients with Locally Advanced or Metastatic Solid Tumors. Sponsor Protocol No. GO29313. WIRB Protocol No. 20141118
Camidge, David14-1476
A Phase 1 Dose Escalation and Phase 2 Randomized Double-Blind Study of Veliparib in Combination with Carboplatin and Etoposide as a Therapy of Treatment-Naïve Extensive Stage Disease Small Cell Lung Cancer. Sponsor Protocol No. M14-361. WIRB Protocol No. 20142537
Camidge, David14-1489
A Randomized, Open-Label, Multicenter Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Co-Administration of ABT-493 and ABT-530 With and Without RBV in Subjects With Chronic Hepatitis C Virus (HCV) Genotype 2 or Genotype 3 Infection (SURVEYOR-II). Sponsor Protocol No. M14-868. WIRB Protocol No. 20141974
Everson, Greg14-1494
A Phase 2B Prospective, Randomized, Double-blinded, Placebo-controlled Clinical Study Demonstrating the Efficacy and Safety of Rebiotix RBX2660 (microbiota suspension) for the Treatment of Recurrent Clostridium difficile Infection. Sponsor Protocol No. 2014-01. WIRB Protocol No. 20141261
Freeman, Stephen14-1538
Weekes, Colin14-1551
TIGER 1: A Randomized, Open-Label, Phase II Study of CO-1686 or Erlotinib as First-Line Treatment of Patients with EGFR-Mutant Advanced Non-Small Cell Lung Cancer (NSCLC) Sponsor Protocol No. CO-1686-022 WIRB Protocol No. 20142085
Camidge, David14-1569
An Open-Label, Multi-Center, 48-Week Study with a Concurrent Untreated Control Arm to Evaluate the Efficacy and Safety of Eteplirsen in Duchenne Muscular Dystrophy. Sponsor Protocol No. 4658-301-a1. WIRB Protocol No. 20141230
Parsons, Julie14-1629
Multicenter, open-label, randomized, controlled phase III clinical study of the efficacy and safety of photodynamic therapy using porfimer sodium for injection as treatment for unresectable advanced perihilar cholangiocarcinoma Sponsor Protocol No. PIN-PHO1201 WIRB Protocol No. 20140456
Shah, Raj14-1650
A Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter, Multiregional, One Year Study to Assess the Efficacy and Safety of Twice Daily Oral Rifaximin Delayed Release Tablets for Induction of Clinical Remission with Endoscopic Response at 16 Weeks followed by Clinical and Endoscopic Remission at 52 Weeks in Subjects with Active Moderate Crohn's Disease. Sponsor Protocol No. RECD3125. WIRB Protocol No. 20141667
Gerich, Mark14-1659
A Comparison of Soy Protein versus Soy-Dairy Protein-blend Containing Foods in the Colorado Diet for Weight loss and Maintenance. WIRB Protocol No. 20150081
Hill, James14-1666
A Multicenter, Randomized, Open-Label Phase 2b Study to Investigate the Efficacy and Safety of Aldoxorubicin Compared to Topotecan in Subjects with Metastatic Small Cell Lung Cancer Who Either Relapsed or Were Refractory to Prior Chemotherapy Sponsor Protocol No. ALDOXORUBICIN-P2-SCLC-01 WIRB Protocol No. 20141373
Doebele, Robert14-1673

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