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​​Representative RNA Bioscience Publications

Tom Anchordoquy

  1. Relating toxicity to transfection: using sphingosine to maintain prolonged expression in vitro. 2015. Mol. Pharm.
  2. Cholesterol domains enhance transfection. 2013. Ther. Deliv.
  3. Ligands located within a cholesterol domain enhance gene delivery to the target tissue. 2012. J. Control Release. ​
David Barton
  1. RNase L targets distinct sites in influenza A virus. 2015. J. Virol.
  2. Structural features of a picornavirus polymerase involved in the polyadenylation of viral RNA. 2013. J. Virol. ​
  3. Ribonuclease L and metal-ion-independent endoribonuclease cleavage sites in host and viral RNAs. 2014. Nucl. Acids Res. 
David Bentley
  1. Effects of transcription elongation rate and Xrn2 exonuclease activity on RNA polymerase ii termination suggest widespread kinetic competition.​ 2015. Mol. Cell. 
  2. Pre-mRNA splicing is facilitated by an optimal RNA polymerase II elongation rate. 2014. Genes and Dev. 
  3. mRNA decapping factors and the exonuclease Xrn2 function in widespread premature termination of RNA polymerase II transcription. 2012. Mol. Cell.
  4. Coupling mRNA processing with transcription in time and space. 2014. Nat. Rev. Genet. 

Tom Blumenthal​

  1. Polycistronic pre-mRNA processing in vitro: snRNP and pre-mRNA role reversal in trans-splicing. 2012. Genes and Dev. 
  2. A global analysis of C. elegans trans-splicing​. 2011. Genome Res. 

Richard Davis

  1. Transcription in pronuclei and one- to four-cell embryos drives early development in a nematode. 2014. Curr. Biol. 
  2. Silencing of germline-expressed genes by DNA elimination in somatic cells. 2012. Dev. Cell. 
  3. Deep small RNA sequencing from the nematode Ascaris reveals conservation, functional diversification, and novel developmental profiles. 2011. Genome Res.
  4. microRNAs are involved in the regulation of ovary development in the pathogenic blood fluke Schistosoma japonicum. 2016.PLOS Pathogens. ​

​Tom Evans

  1. Modifiers of solid RNP granules control normal RNP dynamics and mRNA activity in early development​. 2015. J. Cell Biol. 
  2. Translation repressors, an RNA helicase, and developmental cues control RNP phase transitions during early development. 2013.Dev. Cell. 
  3. Maternal mRNAs are regulated by diverse P body–related mRNP granules during early Caenorhabditis elegans development. 2008. J. Cell Biol. 

Heide Ford

  1. The Six1 oncoprotein downregulates p53 via concomitant regulation of RPL26 and microRNA-27a-3p. 2015. Nat. Comm.
  2. Twist1-induced mir-424 reversibly drives mesenchymal programming while inhibiting tumor initiation. 2015. Cancer Res.

Jay Hesselberth

  1. Global analysis of RNA cleavage by 5'-hydroxyl RNA sequencing.​ 2015. Nucl. Acids Res.
  2. Ribose-seq: global mapping of ribonucleotides embedded in genomic DNA.​ 2015. Nature Methods. 
  3. A homolog of lariat-debranching enzyme modulates turnover of branched. RNA. 2014. RNA. 
  4. Ribonuclease L and metal-ion-independent endoribonuclease cleavage sites in host and viral RNAs​. 2014. Nucl. Acids Res. 

Aaron Johnson​

  1. An RNA matchmaker protein regulates the activity of the long noncoding RNA HOTAIR. 2016. In Press.
  2. Heterochromatic gene silencing by activator interference and a transcription elongation barrier. 2013. J. Biol. Chem.
  3. Reconstitution of Heterochromatin-Dependent Transcriptional Gene Silencing. 2009. Mol. Cell​.

Peter Kabos

  1. Genome-wide analysis of miRNA-mRNA interactions in marrow stromal cells. 2014. Stem Cells.
  2. HITS-CLIP reveals key regulators of nuclear receptor signaling in breast cancer. 2014. Breast Cancer Res. Treat.​

Jeffrey Kieft

  1. The structural basis of pathogenic subgenomic flavivirus RNA (sfRNA) production​. 2014. Science.
  2. Initiation of translation in bacteria by a structured eukaryotic IRES RNA. 2015. Nature. 
  3. A dynamic RNA loop in an IRES affects multiple steps of elongation factor-mediated translation initiation. 2015. eLife. 
  4. HCV IRES manipulates the ribosome to promote the switch from translation to elongation. 2013. NSMB. 

​Sandy Martin

  1. Enhanced stability and polyadenylation of select mRNAs support rapid thermogenesis in the brown fat of a hibernator.​ 2015. eLife.  
  2. hnRNPL and nucleolin bind LINE-1 RNA and function as host factors to modulate retrotransposition. 2013. Nucl. Acids. Res. 

Eric Poeschla

  1. Antiviral Protection via RdRP-Mediated Stable Activation of Innate Immunity​. 2015. PLOS Pathogens.
  2. An Essential Role for LEDGF/p75 in HIV Integration. 2006. Science. 

Jennifer Richer

  1. Restoration of miR-200c to ovarian cancer reduces tumor burden and increases sensitivity to paclitaxel. 2012. Mol. Cancer Ther. 
  2. Progesterone downregulation of miR-141 contributes to expansion of stem-like breast cancer cells through maintenance of progesterone receptor and Stat5a. 2015. Oncogene. 
  3. Targets of miR-200c mediate suppression of cell motility and anoikis resistance. 2011. Breast Cancer Res.

Dimitri Simberg

  1. Iron oxide nanoparticles and the mechanisms of immune recognitiono of nanomedicines. 2016. Nanomedicine.
  2. Modulatory Role of Surface Coating of Superparamagnetic Iron Oxide Nanoworms in Complement Opsonization and Leukocyte Uptake. 2015. ACS Nano. 
  3. Targeting of perfluorocarbon microbubbles to selective populations of circulating blood cells. 2009. J Drug Target.

Lori Sussel 

  1. βlinc1 encodes a long noncoding RNA that regulates islet β-cell formation and function.​​ 2016. Genes and Dev. 
  2. Epigenetic modifications and long noncoding RNAs influence pancreas development and function. 2015.  Trends in Genetics.

​Linda van Dyk 

  1. Gammaherpesvirus small noncoding RNAs are bifunctional elements that regulate infection and contribute to virulence in vivo.​​ 2015. MBio.
  2. Viral cyclins mediate separate phases of infection by integrating functions of distinct mammalian cyclins. 2012. PLOS Pathogens. ​
  3. Mature and functional viral miRNAs transcribed from novel RNA polymerase III promoters. 2010. RNA.

Rui Zhao​

  1. Brr2 plays a role in spliceosomal activation in addition to U4/U6 unwinding. 2015. Nucleic Acids Res.
  2. Comprehensive in vivo RNA-binding site analyses reveal a role of Prp8 in spliceosomal assembly. 2013. Nucleic Acids Res.
  3. Structural evidence for consecutive Hel308-like modules in the spliceosomal ATPase Brr2.​ 2009. NSMB.