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Anne Lynch, Associate Professor

M.D. University College, Dublin, Ireland


 

Department of Obstetrics & Gynecology
Section of Maternal Fetal Medicine 

Campus Box 8309
Academic Office 1, Room 4203
Phone: 303-724-2016

Anne.Lynch@ucdenver.edu

Dr. Lynch directs the Perinatal Database and the Colorado Baby Blanket Research Program in the Department of Obstetrics and Gynecology. The aim of the “Baby Blanket” program is to link data (medical, markers from biological samples, ultrasound data, laboratory data) obtained during pregnancy with adverse perinatal outcomes and to provide a resource for investigators across the Anschutz Medical Campus to conduct perinatal research.

Dr. Lynch is an established NIH and American Heart Association investigator on the role of the complement system in adverse pregnancy outcomes.  She is also the site Principal Investigator for the NICHD sponsored Effects of Aspirin in Gestation and Reproduction (EAGeR) project, a multicenter, randomized, controlled trial to study the effects of low dose aspirin on pregnancy loss.  She co-directs the Child Maternal Health Program of the Colorado Clinical and Translational Sciences Institute (CCTSI).  She is also a coinvestigator on the Maternal Fetal Medicine Units (MFMU) network, and the National Children’s Study and is a faulty member of the Center for Women’s Health Research at the University of Colorado School of Medicine  At a community level she is a co-chair of the Healthy Women Healthy Babies​ organization.

  

Lynch A, Byers T, Emlen W, Rynes D, Shetterly SM, Hamman RF.  Association of antibodies to beta2-glycoprotein 1 with pregnancy loss and pregnancy-induced hypertension: a prospective study in low-risk pregnancy.  Obstet Gynecol. 1999 Feb;93(2):193-8.

Lynch A, McDuffie R Jr, Murphy J, Faber K, Orleans M. Preeclampsia in multiple gestation: the role of assisted reproductive technologies.  Obstet Gynecol. 2002 Mar;99(3):445-51. This paper was selected for abstraction in the 2003 Year Book of Obstetrics and Gynecology and also in the Permanente Journal, Summer 2002/Vol 6 No 3.  The paper also received a Roy M. Pitkin award.

Lynch A, McDuffie R, Murphy J, Faber K, Leff M, Orleans M.  Assisted reproductive interventions and multiple birth.  Obstet Gynecol. 2001 Feb;97(2):195-200.

Lynch A, McDuffie R, Stephens J, Murphy J, Faber K, Orleans M.  The contribution of assisted conception, chorionicity and other risk factors to very low birthweight in a twin cohort.   BJOG. 2003 Apr;110(4):405-10.

Lynch AM.  Neonatal Outcomes after Elective Cesarean Section.  Obstet Gynecol 2009;113(6):1231-8. Featured article in Obstet Gynecol and received an editorial in the Lancet

Lynch A, Murphy J, Byers T, Gibbs R, Neville  M, Giclas P, Salmon J, Holers VM.  Alternative Complement Pathway activation fragment Bb in early pregnancy as a predictor of preeclampsia Am J Obstet Gynecol. 2008 Jan 24;20.  PMID: 18221926

Lynch AM, Gibbs RS, Murphy JR, et al. Complement activation fragment Bb in early pregnancy and spontaneous preterm birth. Am J Obstet Gynecol 2008;199:354.e1-354.e8.with editorial from Robert Silver MD  American Journal of Obstetrics and Gynecology 2008;199: 327-328 . PMID: 18928972

Lynch AM, Murphy J, Gibbs R, Levine R, Giclas P, Salmon J, et al. The Interrelationship of Complement Activation Fragments and Angiogenesis–Related Factors in Early Pregnancy and their Independent Association with Preeclampsia.  BJOG;117(4):456-62. PMID: 20074261

Lynch AM, Salmon JE. Dysregulated complement activation as a common pathway of injury in preeclampsia and other pregnancy complications. Placenta May 2010.

Lynch AM, Gibbs RS, Murphy JR, Giclas PC, Salmon JE, Holers VM. Early elevations of the complement activation fragment C3a and adverse pregnancy outcomes.  Obstet Gynecol. 2011 Jan;117(1):75-83.PMID: 21173647.

Fisher B, Scott J, Hart J, Winn VD, Gibbs RS, MD, Lynch AM.  Behaviors, Attitudes, and Perceptions Regarding Seasonal and H1N1 Influenza Vaccination During the 2009-2010 Season.  Am J Obstet Gynecol. 2011 Jun;204(6 Suppl 1):S107-11. Epub 2011 Feb 22.  PMID: 21419386.

Kun

ze, M, Hart JE, Lynch AM, Gibbs RS. Intrapartum management of premature rupture of membranes: effect on cesarean delivery rate. Obstet Gynecol2011 Dec;118(6):1247-54.

Lynch AM, Eckel RH, Murphy JR, Gibbs RS, West NA, Giclas PC,  Salmon JE, Holers VMl. Prepregnancy obesity and complement system activation in early pregnancy and the subsequent development of preeclampsia. Am J Obstet Gynecol2012 May;206(5):428 e1-8


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