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Program in Reproductive Sciences Journal Club




Journal Club is held once a month on Fridays at 1pm in RC2 3rd floor conference room P15-3015, unless otherwise noted.

This student-run journal club includes a formal presentation of the selected article and lively discussion and critique. Light lunch is provided.

Student Contact:  Adrianne Stefanski
Faculty Advisor: Dr. K. Joseph Hurt, MD, PhD,

For additional information or to request a PDF copy of the article please contact:

Barb.Hughes@ucdenver.edu
Tel: (303) 724-3506
Fax: (303) 724 3512

Sponsored by the Graduate Program in Reproductive Sciences.

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2013 - 2014 PiRS Journal Club


 Date Presenter Paper Citation
09/10/2013 Winn and Hurt Labs Reduced cystathionine γ-lyase and increased miR-21 expression are associated with increased vascular resistance in growth-restricted pregnancies: hydrogen sulfide as a placental vasodilator. Cindrova-Davies T, et al. Am J Pathol. 2013 Apr;182(4):1448-58​. PMID:23410520
10/04/2013 Jaime Fornetti In vitro mimicking of estrous cycle stages in porcine oviduct epithelium cells: estradiol and progesterone regulate differentiation, gene expression, and cellular function. Chen S, Einspanier R, Schoen J. Biol Reprod. 2013 Sep 12;89(3):54. PMID: 23904510
11/15/2013 Becca Green Context-dependent wiring of Sox2 regulatory networks for self-renewal of embryonic and trophoblast stem cells. Adachi, K et al. Molecular Cell 52, 1-13, November 7, 2013. PMID: 24120664
12/06/2013 Adrianne Stefanski Parental olfactory experience influences behavior and neural structure in subsequent generations. Dias, B. and Ressler, K. Nature Neuroscience, 2013 Dec 1. doi:10.1038/nn.3594
01/10/2014 Linnea Schmidt Osteocalcin regulates murine and human fertility through a pancreas-bone-testis axis. Oury, F, Ferron, M, Huizhen, W, Confavreux, C, Xu, L, et al. The Journal of Clinical Investigation, 2013;123(6)2421-2433. PMID: 23728177
02/14/2014 Emily Busta Low paternal dietary folate alters the mouse sperm epigenome and is associated with negative pregnancy outcomes”. Lambrot, R, Xu, C, Saint-Phar, S, Chountalos, G., et al. Nat. Commun. 4:2889 doi: 10.1038/ncomms3889 (2013). PMID: 24326934
03/07/2014 Allyson Booth
Gutierrez-Hartmann lab
Caffeine-induced activated glucocorticoid metabolism in the hippocampus causes hypothalamic-pituitary-adrenal axis inhibition in fetal rats. Xu, D, Zhang, B, Liang, G, et al. PLoS ONE 7(9):e44497 (2012) PMID: 22970234
04/04/2014 Michael Oliphant Paternal effect on embryo quality in diabetic mice is related to poor sperm quality and associated with decreased glucose transporter expression Kim, ST, Moley, KH Reproduction (2008) 136:313-322 PMID: 18558660
05/20/2014 Oliwier Dziadkowiec, PhD
Director, Center for Nursing Research
UCD College of Nursing
Erroneous analyses of interactions in neuroscience: a problem of significance. Nieuwenhuis, S, Forstmann, BU, Wagenmakers, E-J. Nature Neuroscience (2011) 14:1105-1107 PMID: 21878926

 

2012-2013 PiRS Journal Club Archive


 Date Presenter Paper Citation
9/21/2012 Margaret Heerwagen Cross talk between PKC and CREB in the induction of COX-2 by PGF2α in human amnion fibroblasts. GuoCM, et al. Endocrinology. 2012; 153(10):0000–0000 epub ahead of print 8/23/2012. PMID: 22919060
10/19/2012 Jaime Fornetti NODAL in the uterus is necessary for proper placental development and maintenance of pregnancy. Park, C.B., et al. Biology of Reproduction. 2012 86(6):194, 1-13. PMID:22378764
11/09/2012 Linnea Schmidt Evidence of endoplasmic reticulum stress and protein synthesis inhibition in the placenta of non-native women at high altitude. Yung, HW et al. FASEB J 2012 May; 26(5): 170-1981. PMID 22267338
12/07/2012 Adrianne Stefanski Offspring from Oocytes Derived from in Vitro Primordial Germ Cell-Like Cells in Mice. Hayashi K, Ogushi S, Kurimoto K, Shimamoto S, Ohta H, Saitou M. Science. 2012 Oct 4. pp. 971-975. PMID: 23042295
01/18/2013 Emily Busta Insulin rescues impaired spermatogenesis via the hypothalamic-pituitary-gonadal axis in akita diabetic mice and restores male fertility. Schoeller Erica, Albanna G, Frolova A, Moley K. Diabetes 2012; 61:1869-1878. PMID:22522616
02/15/2013 Rebecca Green Patterns of placental development evaluated by X chromosome inactivation profiling provide a basis to evaluate the origin of epigenetic variation. Penaherrera MS, Jiang R, Avila L, et al. Human Reproduction 2012; 27(6):1745-1753 PMID: 22431562
03/08/2013 Allyson Booth Prenatal exposure to low levels of androgen accelerates female puberty onset and reproductive senescence in mice, Witham EA, et al, Endo​crinology, September 2012, 153(9):4522-4532. PMID: 22778229
04/12/2013 Claire Gustafson Premature delivery influences the immunological composition of colostrum and transitional and mature human milk. Catellote C, Casillas R, Ramirez-Santana C, Perez-Cano FJ, Castell M, Moretones MG, Lopez-Sabater MC, Franch A. J. Nutr. 2011, 141(6):1181-7 PMID: 21508211
05/10/2013 Amanda Allshouse Whole animal experiments should be more like human randomized controlled trials. Muhlhausler BS, Bloomfield FH, Gillman, MW. PLoS Biol 11(2): e1001481. PMID: 23424284

 

2011-2012 PiRS Journal Club Archive


 Date Presenter Paper Citation
9/20/2011 Becca Green The mammalian doublesex homolog DMRT1 is a transcriptional gatekeeper that controls the mitosis versus meiosis decision in male germ cells. Matson CK, et al. Developmental Cell. 2010; 19: 612-624. PMID: 20951351 AND DMRT1 prevents female reprogramming in the postnatal mammalian testis. Matson CK, et al. Nature. 2011; 476: 101-104. PMID: 21775990
10/20/2011 Jamie Fornetti Activation of the maternal immune system induces endocrine changes in the placenta via IL-6. Hsiao EY and Patterson PH. Brain, Behavior, and Immunity. 2011; 25: 604-15. PMID: 21195166
11/18/2011 Margaret Heerwagen Deregulation of the serum- and glucocorticoid-inducible kinase SGK1 in the endometrium causes reproductive failure. Salker MS, et al. Nature Medicine. 2011; 17: 1509-13. PMID: 22001908
1/20/2012 Becca Green Conditional Deletion of MSX Homeobox Genes in the Uterus Inhibits Blastocyst Implantation by Altering Uterine Receptivity. Daikoku T, Cha J, Sun XF, et al. Developmental Cell. 2011; 21: 1014–1025. PMID: 22100262
2/17/2012 Emily Busta Extracellular matrix proteases contribute to progression of pelvic organ prolapse in mice and humans. Budatha, et al. Journal of Clinical Investigation. 2011; 121(5): 2045-59. PMID: 21519142
4/6/2012 Joe Hurt and Laxmi Kondapalli Faculty lecture and paper discussion: "How to read clinical literature: A crash course for the basic scientist." Immediate versus delayed medical treatment for first-trimester miscarriage: a randomized trial. American Journal of Obstetrics & Gynecology. 2012; 206: 215.e1-6. PMID: 22381604
4/20/2012 Linnea Schmidt Oocyte formation by mitotically active germ cells purified from ovaries of reproductive-age women. White, et al. Nature Medicine. 2012; 18(3): 413-21. PMID: 22366948
5/25/2012 Adrianne Stefanski Phase III trial of a weekly methotrexate or pulsed dactinomycin for low-risk gestational trophoblastic neoplasia: a gynecologic oncology group study. Osborne, et al. Journal of Clinical Oncology. 2011; 29(7): 825-31. PMID: 21263100

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