Guarnieri, M. T., B. S. J. Blagg, R. Zhao (in press). A high throughput TNP-ATP displacement assay for screening inhibitors of ATP-binding in bacterial histidine kinases. Assay and Drug Developement Technologies.
Pazy, Y., M. A. Motaleb, M. T. Guarnieri, N. W. Charon, R. Zhao, R. E. Silversmith (2010). Identical phosphatase mechanisms achieved through distinct modes of binding phosphoprotein substrate. PNAS. 107, 1924-1929.
Zhang, L., T. Xu, C. Maeder, L. Bud, J. Shanks, J. Nix, C. Guthrie, J.A. Pleiss, R. Zhao (2009). Structural evidence for consecutive Hel308-like modules in the spliceosomal ATPase Brr2. Nature Structure and Molecular Biology. 16, 731-739.
Patrick, A.N., B.J. Schiemann, K. Yang, R. Zhao*, and H. Ford* (2009). Biochemical and functional characterization of 6 Six1 Branchio-Oto-Renal Syndrome mutations. J. Biol. Chem. 284, 20781-20790. (* Co-corresponding authors)
Yang, K., L. Zhang, T. Xu, A. Heroux, R. Zhao (2008). Crystal structure of the beta-finger domain of Prp8 reveals analogy to ribosomal proteins. PNAS. 105, 13817-22.
Shen, H., X. Zheng, J. Shen, L. Zhang, R. Zhao, M. R. Green (2008). Distinct activities of the DExD/H-box splicing factor hUAP56 facilitate stepwise assembly of the spliceosome. Genes & Development. 22, 1796-1803.
Guarnieri, M., L. Zhang, J. Shen, R. Zhao (2008). The Hsp90 inhibitor radicicol interacts with the ATP-binding pocket of bacterial sensor kinase PhoQ. J. Mol. Biol. 379, 82-93.
Shen, J., L. Zhang, R. Zhao (2007). Biochemical characterization of the ATPase and helicase activity of UAP56, an essential pre-mRNA splicing factor and mRNA export factor. J. Biol. Chem. 282, 22544-22550.
Zhang, L., J. Shen, M. Guarnieri, A. Heroux., K. Yang, R. Zhao (2007). Crystal structure of the C-terminal domain of splicing factor Prp8 carrying retinitis pigmentosa mutants. Protein Science, 16, 1024-1031.
Pena, P. V., F. Davrazou, X. Shi, K. Walter, V. V. Verkhusha, O. Gozani, R. Zhao, and T. G. Kutateladze (2006). Molecular mechanism of H3K4Me3 recognition by Plant Homeodomain of Inhibitor of Growth 2 tumor suppressor. Nature, 442, 100-103.
Zhao, R.*, J. Shen, M. R. Green, M. MacMorris and T. Blumenthal (2004). Crystal structure of UAP56, a DExD/H-box protein involved in pre-mRNA splicing and mRNA export. Structure, 12, 1373-1381. (*. Corresponding author)