* A.k.a. glutaryl-CoA dehydrogenase, GCDH, GCD.
Monday - Friday, 0800 - 1700.
2 - 3 months (depending on growth rate of cultured cells).
Two T-25 flasks of confluent fibroblasts, with plug-seal caps, completely
filled with media. Fibroblasts must be mycoplasma-free.
NOTE: An additional fee of $460 will be charged for skin specimens that have not
been cultured into confluent fibroblasts before shipment.
Send flasks in a Styrofoam box at room temperature. Please include passage number (if known) and any relevant information about the patient.
Interpretive Reference Range:
6.5 – 17.4 nanomoles CO2/hour/mg protein (subject to interpretation).
Diagnosis of glutaric acidemia type 1 (a.k.a. GA 1, glutaric acidemia type I, GA I).
CO2 release assay.
Please note that mutation analysis for GA 1 is performed by the UCD DNA Diagnostic Laboratory.