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NMR Structural Biology Shared Resource Facility at CU Cancer Center


The NMR Shared Resource Facility provides access to state of the art instrumentation to researchers at UCD and its affiliated institutions for the study of the structure and function of biologically important molecules implicated in the development and progression of diseases, including cancer, diabetes, aging, and infectious disease organisms. The NMR facility was established in 1996 with funds provided by the Howard Hughes Medical Institute and the National Cancer Institute. Ongoing support for the NMR facility is provided by the University of Colorado Cancer Center and the School of Medicine.

The NMR facility is located in Room L18-1300 on the first floor of RC-1 South at the CU Anschutz Medical campus.

The NMR Facility is integrated with the 800 and 900 MHz NMR spectrometers that are part of the Rocky Mountain High Filed NMR Resource. Operation and administration of the 800 and 900 MHz NMR spectrometers is presently handled through a consortium of the CU School of Medicine, CU Boulder, and University of Utah and more information can be found here

Instrumentation Available

Spectrometers at CU Anschutz Medical Campus

  • Varian INOVA 500 MHz
    • 5 mm triple resonance 1H/13C/15N probe - sensitivity of 850:1 (ETB)
  • Varian INOVA 600 MHz
    • 5mm triple resonance  1H/13C/15N cold probe - sensitivity > 4000:1 (ETB)
  • Varian 900 MHz Direct Drive NMR system
    • 5 mm triple resonance 1H/13C/15N cold probe with Z-axis gradient

 

Spectrometers at CU Boulder Campus

  • Varian 800 MHz Direct Drive NMR system
    • 5 mm triple resonance 1H/13C/15N cold probe

 

500-NMR 600-NMR