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Adult Medical Genetics Program

Our Faculty & Staff

Luisa Mestroni, MD, Director of Adult Medical Genetics Program

Dr. Mestroni was recruited in 1998 to head the Institute’s Molecular Genetics Program.  Her research team seeks to identify the genetic cause of dilated cardiomyopathy, a leading cause of heart failure, which is primarily inherited and runs in families.  Her team studies adult and child patients, conducting clinical trials that track the appearance and progress of familial cardiomyopathy within family populations.
A primary asset of the CU-CVI is Dr. Mestroni’s Human Genome Project, which contains one of the largest human tissue collections in the world, from explanted human and experimental animal hearts.  Data from the Project has produced discoveries by institute scientists that have resulted in new diagnostic techniques and improvements in the way physicians and researchers worldwide approach and treat heart failure.

Matthew Taylor, MD, Director of the Adult Medical Genetics Clinic

Dr. Taylor is trained in both internal medicine and clinical genetics, representing a new generation of internists who are particularly suited to attend to the challenges posed by genetic medicine.  Dr. Taylor attended medical school at the University of Southern California.  He completed residency training and a fellowship in Medical Genetics at the University of Colorado.
As Director of the Adult Medical Genetics Clinic, Dr. Taylor’s principle goal is to develop an adult genetics clinic and consultative service, specializing in the diagnostic evaluation, management, and genetic counseling of adults with known or suspected genetic conditions.  The Adult Medical Genetics Clinic complements the efforts of the Hereditary Cancer Clinic and the Cardiovascular Genetics Clinic, also based at the University Hospital.
Beyond his clinical roles, Dr. Taylor is involved in a number of research projects related to adult genetic conditions, including genetic studies of inherited cardiomyopathies, polycystic kidney disease (PKD), and lysosomal storage diseases.  The cardiomyopathy and PKD research focuses on the molecular genetics of these two disorders and calls upon the services of the state-of-the-art UCD Genotyping, Linkage Analysis and Mutation Screening Core (Directed by Pam Fain PhD). 
s genetic principles have not traditionally featured prominently in internal medicine training, Dr. Taylor will also serve as a resource for the education of Housestaff and faculty physicians about genetics.  The newly created AMGP Monthly Update in Genetics (or "AMGP MUG") is an electronic newsletter targeted at the Medicine Housestaff physicians, providing them with regular exposure to clinical genetic principles.