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 Joaquin Espinosa

Dr. Espinosa assumed the position of Executive Director at the Linda Crnic Institute for Down Syndrome in July 2017. He is also a Professor in the Department of Pharmacology at the University of Colorado Denver School of Medicine, the co-Leader of the Molecular Oncology program at the University of Colorado Cancer Center, and the founding Director of the Functional Genomics Facility at the University of Colorado.

Dr. Espinosa received his B.S. in Biology from the Universidad Nacional de Mar del Plata, Argentina, in 1994, and a PhD in Biology from the Universidad de Buenos Aires, Argentina, in 1999. Supported by a fellowship from the PEW Charitable Trusts, Dr. Espinosa completed his post-doctoral training at the Salk Institute for Biological Studies in La Jolla, California. In 2004, supported by a fellowship from the Leukemia and Lymphoma Society, he began his independent appointment at the University of Colorado Boulder, in the Department of Molecular, Cellular and Developmental Biology. In 2009 he was appointed to the Howard Hughes Medical Institute as an Early Career Scientist, an appointment that he held until his move from Boulder to the Anschutz Medical Campus in 2015.

Dr. Espinosa directs a diverse research program both at the Department of Pharmacology and the Linda Crnic Institute, with an emphasis on understanding how gene networks control cell behavior and organismal function. Their two main focus areas are cancer biology and Down syndrome. To learn more about the research projects in the Espinosa lab and read their publications, please visit their website here.
In his role as the Associate Director for Science and now as the Executive Director, Dr. Espinosa works in collaboration with all the scientists in the Institute, both in the intramural and extramural programs, to identify research priority areas, promote collaborations within and outside the Institute, facilitate interactions with the clinical care operations at the Sie Center for Down Syndrome, facilitate adoption of new technologies, and advance the research mission of the Institute in the national and international arenas.

 Tom Blumenthal

Tom_Blumenthal_CC2 (2).JPGTom Blumenthal received his PhD in Genetics from Johns Hopkins University in 1970, where he worked on bacterial viruses. He was a Whitney Foundation postdoctoral fellow with James Watson at Harvard, where he discovered that a viral replication envyme contains proteins evolved to perform completely different roles for their host bacteria:  protein synthesis elongation. In 1973, he became an Assistant Professor at Indiana University, where he remained until 1996, rising through the ranks to Professor and Chairman of Biological Sciences. In 1980, as a Guggenheim fellow, he did a sabbatical with Sydney Brenner at the Laboratory of Molecular Biology in Cambridge, where he began work on the nematode worm, C. elegans. He studied developmental gene regulation and later began his most well-known work on mechanisms of mRNA processing and chromosomal gene organization. His laboratory is credited with the first discovery of operons in higher organisms. In 1993 he did a sabbatical with Barbara Meyer in Berkeley where he expanded his work on C. elegans mRNA processing. In 1997, he moved to the University of Colorado School of Medicine as Chairman of Biochemistry and Molecular Genetics. In 2006, he moved to the University of Colorado Boulder as Chairman of Molecular, Cellular, and Developmental Biology. He is an elected fellow of the American Academy of Arts and Sciences. He assumed the position of Executive Director of the Linda Crnic Institute for Down Syndrome in 2012 but stepped down in July 2017.  He holds also remains a Professor in Molecular, Cellular and Developmental Biology at the University of Colorado Boulder.

 Huntington Potter

Huntington Potter, PhD
Kurt N. Edith von Kaulla Memorial Professor of Neurology
Director of Rocky Mountain ALzheimer's Desease Center


 Katheleen Gardiner

Kathleen Gardiner, PhD

  • Professor, Department of Pediatrics

Anna and John J. Professor of Genetics