DPTR 7613: Patient Care Seminar III, Instructor
DPTR 7613: Patient Care Seminar III, Instructor1
Hebert J., Subaward/Site Principal Investigator, Enoka, PI. Neuromuscular Electrical Stimulation and Mobility in Multiple Sclerosis. ClinicalTrials.gov: NCT01698086 NIH R03/NICHD, 13-0720 R03HD079508/University of Colorado Boulder (7/1/14-6/30/16). This trial will investigate the added benefits of neuromuscular electrical stimulation, including walking, for persons with multiple sclerosis.
Hebert, PI. Psychometric properties of outcome measures for mobility, beyond walking speed, in multiple sclerosis: a multi-center study (MCS-III-MOB) 1/6/15-1/5/16.
This 1-year, multi-centered, international pilot trial will establish the psychometric properties of multiple tests within the clinical setting for people with MS
Hebert, PI. Associations between persistent symptoms and balance dysfunction in Veterans with chronic mild traumatic brain injury. University of Colorado Department of Physical Medicine and Rehabilitation Research Core Pilot Award (9/1/14-8/31/15). The objective of the study is to investigate the potential associations between dizziness, fatigue, dynamic standing balance and mobility-based balance in Veterans with chronic mTBI. Additionally, the study will test the relationship between these factors and mental health conditions including posttraumatic stress disorder (PTSD) and depression.
Hebert JR, Schenkman M (Co-PIs) National MS Society 10/01/12- 09/30/15 This randomized clinical trial is designed to examine the impact of vision and balance training on fatigue and postural control of individuals with multiple sclerosis. Effort: 15%
Schenkman M (PI), Hebert J, Corboy J. The effects of vestibular rehabilitation on MS-related fatigue: randomized control trial. National Multiple Sclerosis Society, Pilot Research Award: PP1501], 2/08-12/31/09. ($43,774). RCT that examines the benefits of vestibular exercise for people with PD. Role: Co-investigator and study coordinator. Effort: 25% (See below for more information).
Other Research and Scholarly Activity
Hebert JR (PI) National MS Society 10/01/12- 09/30/15 ($536,295) This 3-year randomized controlled trial will determine which patients with MS improve the most in balance, visual stability and subjective fatigue from an exercise program of balance and eye movement exercises. Effort: 30%
Herbert J (Subaward/SPl), Rudroff, (PI) Glucose uptake in response to walking in patients with multiple sclerosis. National Multiple Sclerosis Society/Colorado State University 4/01/13 -3/31/14. ($40,000). The goal of this 1-year pilot study is to identify and compare differences in energy utilization and activation in leg muscles of patients with MS and healthy subjects during a walking test. Effort: 5%
Hebert, PI Visual Stability and the Utility of the Gaze Stabilization Test in Persons with Multiple Sclerosis. 11/15/13-11/14/14. This 1-year pilot trial will establish the utility of the GST in people with MS by investigating discriminant validity and test-retest reliability of the GST for people with MS and age-comparable healthy controls.
Hebert J. Effects of vestibular rehabilitation on MS-related fatigue: randomized control trial. Purpose and primary specific aims: Fourteen week trial designed to determine the effects of a novel approach to the treatment of patients with Multiple Sclerosis. Outcomes include: self-reported fatigue, dizziness and instability, depression, standing-upright control (balance) based on results from Computerized Sensory Organizational Test, and dynamic mobility based on results from Six Minute Walk Test. Three study groups are included: Vestibular Rehabilitation and energy conservation education (Experimental Group), aerobic and stretching and energy conservation education (Exercise Control Group), and non-treatment (Wait-listed Control Group).2
Role: Lead investigator, study coordinator. Study began November 2007, before funding was received from the National Multiple Sclerosis Society. Status: Closed and completed November 2010.
Hebert J. Multiple Sclerosis Pilot: Muscle Fatigue
Purpose: Pilot investigation to determine the response to fatiguing activity in the leg muscles in persons with Multiple Sclerosis. Study began August 2009. Main Sponsor: University of Colorado – Boulder (UCB)
Role: collaborator; prospective subject recruitment. Status: Closed and completed August 2009.
Hebert J. The association between balance and multiple sclerosis fatigue: a correlational pilot study.
Peer Reviewed Publications
Ketelhut NK, Kindred JH, Manago MM, Hebert JR, Rudroff T. (in review) Imbalances of Core Muscle Activation During Treadmill Walking in Patients with Multiple Sclerosis. Journal of Rehabilitation Research & Development.
Rudroff T, Kindred JH, Koo PJ, Karki R, Hebert JR. Asymmetric Glucose Uptake in Leg Muscles of Patients with Multiple Sclerosis during Walking Detected by [18F]-FDG PET/CT. NeuroRehabilitation. 2014 Oct 16, Epub ahead of print.
Hebert JR, Corboy JR. The Association between Multiple Sclerosis-Related Fatigue and Balance as a Function of Central Sensory Integration. Gait and Posture. 2013 May;38(1):37-42.
Vollmer TL, Benedict R, Bennett S, Motl RW, White AT, Bombardier CH, Hebert JR. Exercise as Prescriptive Therapy in Multiple Sclerosis: A Consensus White Paper. Comprehensive Strategies in Multiple Sclerosis. Int J MS Care. 2012 June;14(S3): 2-14.
Hebert JR, Corboy JR, Manago MM, Schenkman M. Effects of Vestibular Rehabilitation on Multiple Sclerosis-Related Fatigue and Upright Postural Control: A Randomized Controlled Trial. Poster Abstracts from the First International Symposium on Gait and Balance in Multiple Sclerosis: Gait and Balance as Biomarkers in MS. Oregon Health & Science University, Portland, OR. Oct 1, 2011. Int J MS Care. 2011; 13(4):199-204.
Hebert JR, Corboy JR, Manago MM, Schenkman M. Effects of Vestibular Rehabilitation on Multiple Sclerosis-Related Fatigue and Upright Postural Control: A Randomized Controlled Trial. Phys Ther. 2011;91(8):1166-1182.
Mark M. Manago, Hebert JR (mentor). Concurrent validity of the Patient-Specific Functional Scale and the Timed 25-Foot Walk Test in People with Multiple Sclerosis [poster presentation]. Presented at: Third International Symposium on Gait and Balance in Multiple Sclerosis: Selecting the Right Measures. St. Louis, MO. Oct 18-19, 2013
Hebert JR, Corboy JR, Manago MM, Schenkman M. Effects of Vestibular Rehabilitation on Multiple Sclerosis-Related Fatigue and Upright Postural Control: A Randomized Controlled Trial. Poster Abstracts from the First International Symposium on Gait and Balance in Multiple Sclerosis: Gait and Balance as Biomarkers in MS. Oregon Health & Science University, Portland, OR. Oct 1, 2011. Int J MS Care. 2011; 13(4):199-204.3
Baudry S, Hebert JR, Enoka JA, Enoka RM, Rudroff T. Influence of load compliance on muscle fatigue in persons with multiple sclerosis. International Society of Biomechanics, 23rd Annual Meeting. Brussels; July 2011.