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Title

Integrative Omics of COPD

Project Description

The mission of our lab is to understand the mechanisms of how cigarette smoke leads to the development of chronic obstructive pulmonary disease (COPD), the third leading cause of death in the United States. To achieve this goal, we have generated large scale genetic, genomic, proteomic, and metabolic profiles on 10,300 subjects in the NIH sponsored COPDGene cohort and 3,000 subjects from the SPIROMICS cohorts. We use these Omics data to identify novel diagnostic and therapeutic targets. Our laboratory also uses mouse models to study the mechanisms of cigarette smoke induced lung disease.

Area of Study

Pulmonary and Critical Care

Populations

 

Method

Cell Biology, Molecular Biology, and Genetics

Disease or Symptom

COPD

Department

Medicine

Mentor Location

1400 Jackson St., Denver, CO

Mentor Contact Number

303-270-2014

Mentor Email

bowlerr@njhealth.org

Website

http://www.nationaljewish.org/research/programs-depts/medicine/labs/bowler-lab/

Mentor Name

Bowler, Russell

Funding Department/Program

Medicine

Status

Current

Display on public listing?

Yes

Upload Date

 

Attachments

Created at 12/18/2015 8:32 AM by Ross, Randy
Last modified at 8/14/2019 12:37 PM by Zoghby, Caitlin