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Title

Role of Six1 homeobox gene in ovarian tumorigenicity

Status

Open

Project Description

The Behbakht lab in association with collaborators has been studying the role of the Six1 homeobox gene in the pathogenesis of ovarian cancer for the past 8 years and has secured DOD and NIH funding.  The current projects focus Six1 overexpression in an ex-vivo tissue slice model obtained from patient tumors.  The hypothesis is that Six1 expression alters chemosensitiviy and sensitivity to apoptotic stimuli.  This is a unique way to study the primary tumor in its microenvironment without using mouse models

Mentor Name

Behbakht, Kian

Mentor Location

Academic Office One - Room 4413

Mentor Contact Number

303-724-3522

Mentor Contact Email

kian.behbakht@ucdenver.edu

Specialty

Enter Choice #1

Preceptor Name

 

Student

 

Department

Obstetrics and Gynecology

Funding Department/Program

Obstetrics and Gynecology

Area of Study

Hematology and Oncology

Populations

Women

Method(s)

Cell Biology, Molecular Biology, and Genetics

Disease or Symptom

Cancer

Faculty/Lab Website

 

Display on public listings?

Yes

Attachments

Created at 10/5/2010 2:26 PM by Vetter, Stephanie
Last modified at 10/31/2014 2:24 PM by Miller, Cody