Research in the Vasiliou lab focuses on cellular mechanisms against oxidative stress caused by physical agents (e.g., UV radiation), and the metabolism of both endogenous and foreign chemicals. The roles of several aldehyde dehydrogenases (ALDH3A1, ALDH1A1, ALDH7A1 and ALDH3B1) expressed in tissue-specific manner are currently studied using genetically engineered cell lines and transgenic knockout mouse lines. Dr. Vasiliou and Dr. Petrash collaborate on mechanisms of lens transparency and cataract. Dr. Vasiliou has extensive experience working with students and currently directs the Toxicology Program in the Department of Pharmaceutical Sciences in University of Colorado School of Pharmacy.