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Title

Controlling AutoAggressive T cells in type 1 diabetes and Multiple Sclerosis

Status

Open

Project Description

 

We defined the population of T cells that attack islets in type 1 diabetes and attack CNS in multiple sclerosis. We have discovered a unique means to control those pathogenic cells and thus are undergoing drug development. We will continue to examine T1D and MS patients, further characterize immune cells and examine how our newly developed drug affects pathogenic T cells. Studies will include animal models of the disease, creating new treatment parameters, and examination of ex vivo leukocytes from patient populations. This project will lead to filing with the FDA for final drug approval.

 

Mentor Name

Wagner, David

Mentor Location

School Of Pharmacy Bldg

Mentor Contact Number

303-724-4787

Mentor Contact Email

david.wagner@ucdenver.edu

Specialty

Enter Choice #1

Preceptor Name

 

Student

 

Department

Medicine

Funding Department/Program

Medicine

Area of Study

Immunology and Autoimmune Diseases

Populations

Adolescents; Adults; African American; Asian; Hispanic-Latino(a); Men; Native Americans; Pregnant Woman; School-age Children; Students; Veterans; Women; Young Adults

Method(s)

Clinical Trials

Disease or Symptom

Multiple Sclerosis

Faculty/Lab Website

 

Display on public listings?

No

Attachments

Created at 7/12/2012 8:27 AM by Watts, Katie
Last modified at 1/6/2014 9:25 AM by Watts, Katie