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Bladder Cancer


Urology maintains an active translational molecular biology lab focused on identifying the molecular mechanisms leading to bladder cancer metastasis and their potential applications to patients with this disease. Our laboratory is at the forefront in the development of biomarkers and therapeutics in bladder cancer.
Our laboratory uses in vitro and in vivo models to study the dynamics between oncogenes identified as promoters of tumorigenesis and metastasis including the small GTPase Ral in mediating tumor cell motility, a necessary step leading to tumor invasion, and CD24, a cell surface protein whose expression correlates directly with tumorigenic, metastasis, and patient survival.