Skip to main content
Sign In
 

MR Physics


Mark Brown, PhD

Yiping Du, PhD

Methodological Development of fMRI Techniques

Dr. Du has developed a volume-selective z-shim technique to reduce the susceptibility artifacts in fMRI studies. In this technique, z-shim compensation is applied only to a few selected slices in a whole brain fMRI study. As a result, the time penalty for multiple acquisitions at the z-shim slices is greatly reduced. Using this technique, BOLD activations can be effectively detected at the orbito-frontal cortex in whole brain fMRI with a TR of 2 seconds (see Fig. 1). This technique has currently being used in the fMRI studies of drug addiction, alcoholism, and behavioral disorders.

1 
Quantitative Mapping of Myelin Water Fraction (MWF) in the brain
Artifact reduction in Echo-Planar Spectroscopic Images (EPSI)
Improving the accuracy of functional maps
Novel ROC Methods for Assessing Processing Techniques
Exploratory Analysis Using ICA