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Physical Medicine and Rehabilitation

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Daniel Lammertse, MD


Associate Clinical Professor of Physical Medicine and Rehabilitation

Contact

   Office Phone:  303-789-8220
   Fax:  303-789-8470 
   Email:  dlammertse@craighospital.org

Affiliations
   Craig Hospital

Board Certifications
   Physical Medicine and Rehabilitation, Spinal Cord Medicine. Electrodiagnostic Medicine

Research Activites

CLINICAL TRIAL LNVESTIGATOR EXPERIENCE:

Intrathecal Baclofen for Treatment of Spasticity in Spinal Cord Injury 1991-1992
Sponsor: Medtronic

Platelet-Derived Growth Factor for Wound Healing in Spinal Cord Injury 1992-1993 Sponsor: Novo Nordisk
A Randomized, Stratified, Double-Blind, Multicenter Study of the Efficacy 1992-1998 and Safety Of Sygen (GM-l) Vs Placebo Following Standard Methylprednisolone Sodium Succinate (MPSS) Therapy in the Treatment of Acute Spinal Cord Injury Sponsor: Fidia Pharmaceuticals

Evaluation of an Implantable Sacral Anterior Root Stimulator for Bladder 1996-1998 Control In Spinal Cord Injury Sponsor: NeuroControl Corporation

A Multi-Site, Open-Label Study to Evaluate 250mg of Oral Neotrorm BID 2000-2002 in Patients With Subacute Complete Spinal Cord Injury over 12 Weeks Sponsor: NeoTherapeutics

Double-Blind, Placebo-Controlled, Parallel Group Study to Evaluate Safety, 2000-2001 Tolerability and Activity of Oral Fampridine-SR in Subjects with Chronic, Incomplete Spinal Cord Injury, and to Evaluate a New Patient Diary/Questionnaire Sponsor: Acorda Therapeutics

Open-Label Extension of Double-Blind, Placebo-Controlled, Parallel Group Study 2002-2004 To Evaluate Safety, Tolerability and Activity of Oral Fampridine-SR in Subjects With Chronic, Incomplete Spinal Cord Injury Sponsor: Acorda Therapeutics

Double-Blind, Placebo-Controlled, 4-Week Parallel Group Study to Evaluate 2002-2004 Safety and Efficacy of Oral Fampridine-SR in Subjects with Moderate to Severe Spasticity Resulting From Chronic, Incomplete Spinal Cord Injury Sponsor: Acorda Therapeutics

Open-Label Extension of Double-Blind, Placebo-Controlled, 4-Week Parallel 2003-2004 Group Study to Evaluate Safety and Efficacy of Oral Fampridine-SR in Subjects With Moderate to Severe Spasticity Resulting from Chronic, Incomplete Spinal Cord Injury Sponsor: Acorda Therapeutics

A Phase II Study of Autologous Incubated Macrophages for the Treatment of 2003-2006 Complete Spinal Cord Injuries Sponsor: Proneuron Biotechnologies

CLINICAL TRIAL ADVISORY/CONSULTATION EXPERIENCE:

Fidia Pharmaceutical Corporation: Sygen GM-l Multicenter Trial-Protocol Development 1992 Advisory Meeting

Acorda Therapeutics: Fampridine-SR Multicenter Trial-Protocol Development Advisory 1998-2003 Meetings

Proneuron Biotechnologies: Autologous Incubated Macrophage Trial-Protocol Development Advisory Meeting 2002 Member Clinical Trial Steering Committee 2003-2006

International Campaign for Cures for spinal cord injury Paralyis (ICCP) Clinical Trials 2004-present Guidelines Workgroup

Undergraduate: Ohio State University Columbus, Cum Laude Phi Beta Kappa

Medical Degree: Ohio State University Columbus, Cum Laude Alpha Omega Alpha

Residency: Ohio State University College of Medicine Department of Physical Medicine Chief Resident

SCIENTIFIC JOURNAL PUBLICATIONS:

Jones LAT, Lammertse DP, Charlifue SB, Kirshblum SC, et a!. A phase 2 autologous cellular therapy in patients with acute, complete spinal cord injury: pragmatics, recruitment, and demographics. Spinal Cord advance online publication, 13 April 2010; doi:10.1038/sc.2010.29

Falci SP, Indeck C, Lammertse DP. Posttraumatic spinal cord tethering and syringomyelia: surgical treatment and long-term outcome. J Neurosurg Spine 2009;11:445-460

Blight A, Curt A, Ditunno JF, Dobkin B, Ellaway P, Fawcett J, Fehlings, M, Grossman RG, Lammertse DP, Privat A, Steeves J, Tuszynski M, Kalichman M, Guest JD. Position statement on the sale of unproven cellular therapies for spinal cord injury: The International Campaign for Cures for Spinal Cord Injury Paralysis (Letter). Spinal Cord 2009; 47: 713-714

Liu JC, Patel A, Vaccaro AR, Lammertse DP. Point/Counterpoint: Methylprednisolone after traumatic spinal cord injury: Yes or No? PM&R 2009;1: 669-673

Whiteneck G, Dijkers M, Gassaway J, Lammertse D. The SCIRehab Project: Classification and Quantification of Spinal Cord Injury Rehabilitation Treatments. J Spinal Cord Med 2009;32(3):249-250.

Alexander MS, Anderson KD, Biering-Sorensen F, Blight AR, Brannon R, Bryce TN, CreaseyG, Catz A, Curt A, Donovan1 W, Ditunno J, Ellaway P, Finnerup NB, Graves D, Haynes BA, Heinemann A W, Jackson AB, Johnston MV, Kalpakjian CZ, Kleitman N, Krassioukov A, Krogh K, Lammertse D, Magasi S, Mulcahey MJ, Schurch B, Sherwood A, Steeves JD, Stiens S, Tulsky DS, van Hedel, HJA, and Whiteneck G. Outcome measures in spinal cord injury: recent assessments and recommendations for future directions. Spinal Cord 2009; 47: 582-591; doi:10.1038/sc.2009.18; published online 21 April 2009

Jha A, Lammertse DP, ColI JR, Charlifue S, Coughlin CT, Whiteneck GG, Worley, G. Apolipoprotein E £4 Allele and Outcomes of Traumatic Spinal Cord Injury. J Spinal Cord Med 2008;31(2):171-6.

Fawcett JW, Curt A, Steeves JD, Coleman WP, Tuszynski MH, Lammertse D, et al. Guidelines for the condnct of clinical trials in spinal cord injury as developed by the ICCP panel: spontaneous recovery after spinal cord injury and statistical power needed for therapeutic clinical trials. Spinal Cord 2007; 45:190-205. advance online publication, 19 December 2006; doi:10.1038!sj.sc3102007

Steeves JD, Lammertse D, Curt A, Fawcett JW, Tuszynski MH, Ditunno JF, et at Guidelines for the conduct of clinical trials in spinal cord injury as developed by the ICCP panel: clinical trial outcome measures. Spinal Cord 2007; 45: 206-221. advance online publication, 19 December 2006; doi:10.1038!sj.sc.3102008

Tuszynski MH, Steeves JD, Fawcett JW, Lammertse D, Kalichman M, Rask C, et al. Guidelines for the conduct of clinical trials in spinal cord injury as developed by the ICCP panel: clinical trial inclusion/exclusion criteria and ethics. Spinal Cord 2007: 45:222-231. advance online publication, 19 December 2006; doi:10.1038!sj.sc.3102009

Lammertse D, Tuszynski MR, Steeves JD, Curt A, Fawcett JW, Rask C, et al. Guidelines for the conduct of clinical trials in spinal cord injury as developed by the ICCP panel: clinical trial design. Spinal Cord 2007; 45:232-242. advance online publication, 19 December 2006; doi:10.1038!sj.sc.3102010

Cardenas DD, Ditunno J, Graziani V, Jackson AB, Lammertse D, Potter P, Sipski M, Cohen R, Blight AR. Phase 2 trial of sustained-release fampridine in chronic spinal cord injury. Spinal Cord 2007;45:158-168

Shavelle Rl"W, DeVivo MJ, Strauss DJ, Paculdo DR, Lammertse DP, Day, SM. Long-term survival of persons ventilator dependent after spinal cord injury. J Spinal Cord Med 2006; 29:511-519

Lammertse DP, Dungan D, Dresibach J, Falci S, Flanders A, Marino R, Schwartz E. Neuroimaging in Traumatic Spinal Cord Injury: An Evidence-Based Review for Clinical Practice and Research. Report of the NIDRR Measures Meeting Neuroimaging Committee. J Spinal Cord Med 2007;30:2005-214 (Awarded Best Paper published by ASIA Member, American Spinal Injury Association 2007)

Jha A, Lammertse D, Charlifue S, Clayton G. A review of current clinical trials for improving neurological outcomes. Top Spinal Cord Inj Rehabil2006; 11(3):86-100

Kogos SC, Richards JS, Banos JR, Ness TJ, Charlifue, SW, Whiteneck GG, Lammertse DP. Visceral pain and life quality in persons with spinal cord injury: a brief report. J Spinal Cord Med 2005;28:333-337

Lammertse DP. Neurorehabilitation of spinal cord injuries following lightning and electrical trauma. NeuroRehabilitation 2005; 20:9-14

Charlifue A, Lammertse DP, Adkins RH. Aging with spinal cord injury: changes in selected health indices and life satisfaction. Arch Phys Med Rehabil2004;85:1848-53.

Lammertse DP, Jackson AB, Sipski ML. Research from the Model Spinal Cord Injury Systems: findings from the current 5-year grant cycle. Arch Phys Med Rehabil2004;85: 1737-9.

Lammertse DP. Update on Pharmaceutical Trials in Acute Spinal Cord Injury. J Spinal Cord Med 2004;27:319-325

Groah SL, Lammertse DP. Factors associated with survival after bladder cancer in spinal cord injury. J of Spinal Cord Medicine 2003, 26(4):339-344

Ditunno JF, Apple DF, Burns AS, Donovan WH, Hagglund KJ, Lammertse DP, Ragnarsson KJ, Waters RL, Tate DC, Tulsky DS. A view of the future model spinal cord injury systems through the prism of past achievements and current challenges. J ofSpinal Cord Medicine 2003, 26(2): 110-115.

Vellman WP, Hawkes AP, Lammertse DP. Administration of Corticosteroids for Acute Spinal Cord Injury: The Current Practice of Trauma Medical Directors and Emergency Medical System Physician Advisors. Spine 2003, 28(9): 941-947.

Weitzenkamp DA, Whiteneck GG, Lammertse DP. Predictors of personal care assistance for people with spinal cord injury. Archives ofPhysical Medicine and Rehabilitation 2002, 83(10): 1399-1405.

Falci S, Best L, Bayles R, Lammertse D, Starnes C. Dorsal root entry zone microcoagulation for spinal cord injury-related central pain: operative intramedullary electrophysioloigcal guidance and clinical outcome. J Neurosurg(Spine} 2002; 97:193-200

Groah SL, Weitzenkamp DA, Lammertse DP, Whiteneck GG, Lezotte DC, Hamman RF. Excess risk of bladder cancer in spinal cord injury: evidence for an association between indwelling catheter use and bladder cancer. Arch Phys Med Rehabil2002;83:346-51

Lammertse DP, Falci SP. Surgical management of central pain in persons with spinal cord injury: the Dorsal Root Entry Zone (DREZ) procedure. Top Spinal Cord In} Rehabil2001;7(2):41-50

Lammertse DP. Maintaining Health Long-Term with Spinal Cord Injury. Top Spinal Cord In} Rehabil 2001;6(3):1-21

Lammertse DP. Aging with Spinal Cord Injury: Considerations in the Management of Younger Patients. Top Spinal Cord In} RehabU2000;6(suppl): 176-181

Falci SP, Lammertse DP, Best L, Starnes CA, Prenger EC, Stavros AT, Mellick D. Surgical Treatment of Posttraumatic Cystic and Tethered Spinal Cords. J ofSpinal Cord Medicine 1999;22(3):173-81

DeVivo MJ, Krause JS, Lammertse DP. Recent Trends in Mortality and Causes of Death Among Persons With Spinal Cord Injury. Arch Phys Med RehabilI999;80(1l):1411-19

Falci S, Lammertse D, et al. Obliteration of a Posttraumatic Spinal Cord Cyst with Solid Human Embryonic Spinal Cord Grafts: First Clinical Attempt. J ofNeurotrauma 1997;14:875-884

Lammertse D, Recovery of Neurologic Function in Spinal Cord Injury: A Review of New and Experimental Therapies. Top Spinal Cord In} RehabilI997;2(3):95-100

Klingensmith III W, Lammertse D, et at Technetium-99m-MAG3 Renal Studies in Spinal Cord Injury Patients: Normal Range, Reproducibility and Change as a Function of Duration and Level ofInjury. Spinal Cord 1996;34, 338-345.

Yarnell P, Lammertse D. Neurorehabilitation of Lightning and Electrical Injuries. Seminars in Neurology 1995;15(4):391-396

Gerhart K, Johnson R, Menconi J, Hoffman R, Lammertse D. Utilization and Effectiveness of Methylprednisolone in a Population-Based Sample of Spinal Cord Injured Persons. Paraplegia 1995;33:316­321

Cherington M, Yarnell P, Lammertse D. Lighting Strikes: Nature of Neurologic Damage in Patients Evaluated in Hospital Emergency Departments. Ann Int Med 1992;21(5):575-578

Parsons K, Lammertse D. Epidemiology, Prevention, and System of Care in Spinal Cord Disorders. Archives ofPhysical Medicine and Rehabilitation, 1991;72:5293-4

Ragnarsson K, Lammertse D. Anatomy, Pathogenesis, and Research for Neurologic Recovery. Archives of Physical Medicine and Rehabilitation, Study Guide Issue, 1991;72:5295-7

Closson J, Ragnarsson K, Parsons K, Lammertse, D. Comprehensive Management in Spinal Cord Injury. Archives ofPhysical Medicine and Rehabilitation, Study Guide Issue, 1991;72:5298-308

Lammertse D, Yarkony G. Outcomes and Issues of Aging Mter Spinal Cord Injury. Archives ofPhysical Medicine and Rehabilitation, 1991;72:5309-11

PUBLISHED ABSTRACTS:

Lammertse D, Jones L, Charlifue S, Jha A, Grote M, Carlson N, Snyder D. Autologous incubated macrophage treatment in complete spinal cord injury: results of the multicenter trial. J Spinal Cord Med 2009;32(4):449-450 (abs)

Richards JS, Brandenburg n, Endicott J, Lammertse D, Charlifue S, Chen YY, Whiteneck, G. Neuropathic pain following spinal cord injury: defining a day of "manageable pain". J Spinal Cord Med 2005, 28 (2), 147 (abs)

Lammertse DP, Graziani V, Cohen R, Katz MA, Blight AR. Effect of Fampridine-SR on spasticity in patients with chronic, incomplete spinal cord injury: a placebo-controled trial. J Spinal Cord Med 2004; 27:163 (abs)

Lammertse DP, Snively S, Pham-Bowman H, Dannels A, Nolde-Lopez G. Assessment of reduce post-surgical bed rest following pressure ulcer repair. J Spinal Cord Med 2004; 27:191-2 (abs)

Charlifue SB, Lammertse DP, Adkins RH. Aging with spinal cord injury: changes in selected health indices and life satisfaction. J Spinal Cord Med 2004; 27:151 (abs)

Lammertse D, Graziani V, Katz MA, Blight AR. Safety and efficacy of oral Fampridine-SR (sustained-release 4-aminopyridine) in patients with chronic motor-incomplete spinal cord injury. J Spinal Cord Medicine 2002; 25(suppI1):S5-6 (abs)

Weitzenkamp DA, Lammertse DP. A Longitudianl exploration of upper extremity joint painin long-term spinal cord injury survivors. J Spinal Cord Med 2001;24 (supp 1):S6-S7

Groah S, Weitzenkamp DA, Lammertse DP. Excess risk of bladder cancer mortality after spinal cord injury. J Spinal Cord Med 2001;24 (supp 1):S13

Groah S, Lammertse DP. Factors associated with survival after bladder cancer in SCI. J Spinal Cord Med 2001; 24 (supp 1): S17

Groah S, Weitzenkamp D, Lammertse D, et al. Support of a Causal Association Between Indwelling Catheter Use and Bladder Cancer in Spinal Cord Injury. J a/Spinal Cord Medicine 1999;22(1):45, (Abs)

Falci S, Lammertse D, et al. Surgical Treatment of Post-Traumatic Syringomyelia and Tethered Spinal Cords. J a/Spinal Cord Medicine 1999;22(1):40 (Abs).

Falci S, Best L, Lammertse D, et al. Surgical Treatment of Spinal Cord Injury (SCI) Pain Using A New Technique of Intramedullary Electrical Analysis. J a/Spinal Cord Medicine 1999;22(1):39, (Abs)

Seiger A, Holtz A, Akesson E, Azizi M, Ertzgaard P, Hultling C, Kjaeldgaard A, Levi R, RingdonO, Westgren M, Lammertse D, Falci S. Fetal Spinal Cord Grafting in Man. J Neuro Rehab 1998;12(4):198-9, (Abs)

Lammertse D, Charlifue S, Gerhart K, Whiteneck G. The Relative Risk of Bladder Cancer Associated with Indwelling Catheters. J a/Spinal Cord Medicine 1996;19(4):273-274, (Abs)

Falci S, Best L, Froelich J, Lammertse D. Surgical, Imaging and Evoked Potential Correlates of Spinal Cord and Rootlet Tethering in Progressive Posttraumatic Myelopathies. J a/Spinal Cord Medicine 1995;18(2):127, (Abs)

Froelich J, Falci S, Lammertse D, Riedy G, Butterly R. "Assessment of Cord Tethering by Phase Contrast MR CSFlFlow Analysis." J o/Spinal Cord Medicine 1995;18(2):127, (Abs)

Cherington M, Yarnell P, Lammertse D. Severe Immediate Neurologic Injuries Secondary to Exposure to High-Voltage Electricity. Muscle and Nerve 1992;15(10):1196-1197, (Abs)

CLINICAL PRACTICE GUIDELINES:

Lammertse DP, Dungan D, Dresibach J, Falci S, Flanders A, Marino R, Schwartz E. Neuroimaging in Traumatic Spinal Cord Injury: An Evidence-Based Review for Clinical Practice and Research. Report of the NIDRR Measures Meeting Neuroimaging Committee. JSCM, 2007 In Press available on-line at: http://www.asia-spinalinjury.orglbulletinBoard/N euroimagingSCI _ MeasuresMeetProceedings2006.pdf

Garber SL, Biddle AK, Click CN, Cowell JF, Gregorio-Torres TL, Hansen NK, Kloth LC, Lammertse DP, Netscher DT, Reger SI, Rodriguez DJ, Thomason S, Yarkony G. Presure Ulcer Prevention and Treatment Following Spinal Cord Injury: A Clinical Practice Guideline for Health-Care Professionals. Paralyzed Veterans ofAmerica Consortium for Spinal Cord Medicine, 2000

Garber SL, Click CN, Cowell JF, Gregorio-Torres TL, Kloth LC, Lammertse DP. Pressure Ulcers: What You Should Know. A Guide for People with Spinal Cord Injury. Paralyzed Veterans of America Consortium for Spinal Cord Medicine, 2002

CHAPTERS:

Rasouli A, Lammertse DP, Wang MY. "A Review of Clinical Trials and Future Directions for Clinical Studies in Acute Spinal Cord Injury" in Lin VW, et aI, eds. Spinal Cord Medicine: Principles and Practice, 2nd Ed. In Press.

Charlifue S, Lammertse D. "Spinal Cord Injury and Aging" in Lin VW, Cardenas DD, Cutter NC, Frost FS, Hammond MC, et aI, eds. Spinal Cord Medicine: Principles and Practice. New York: Demos 2003

Charlifue SW, Lammertse DP. "Aging in Spinal Cord Injury" in Kirshblum S, Campagnolo DI, DeLisa JA eds. Spinal Cord Medicine. Philadelphia: Lippincott Williams & Wilkins, 2002

Lammertse DP. "Aging in the Nervous System" in Whiteneck GG, Charlifue SW, Gerhart KA, et aI, eds. Aging With Spinal Cord Injury. New York: Demos Publications, 1993.

Lanig I, Lammertse D. "The Respiratory System in Spinal Cord Injury. " Physical Medicine & Rehabilitation Clinics of North America. WB Saunders, Pub., November, 1992.

Lammertse D, "Managing Spasticity" in Zejdlik, Management ofSpinal Cord Injury, Second Edition. Jones and Bartlett, Boston, MA, 1992.

Lammertse D, "Medical Management" in Whiteneck GG, Adler CA, Carter RE, et aI, eds. The Management of High Quadriplegia. New York: Demos Publications, 1989.

BOOKS EDITED:

Whiteneck G, Charlifue S, Gerhart K, Lammertse D, Menter R, Manley S, Seedroff K. Aging with a Spinal Cord Injury. New York: Demos Publications, 1993.

Whiteneck GG, Adler CA, Carter RE, Lammertse DP, Manley S, Menter RR, Wagner KA, Wilmot C. The Management ofHigh Quadriplegia. New York: Demos Publications, 1989