Dr. Jennifer Armstrong-Wells primary research investigates the mechanisms and risk factors for perinatal ischemic brain injury (stroke and cerebral palsy) by examining of inflammatory and coagulation disturbances in the pregnant woman, the placenta, and the fetus. She additionally leads studies on the mechanisms and outcomes after childhood hemorrhagic stroke.
Dr. Timothy Benke's lab studies the function of synapses, the primary means of communication between neurons in the brain. Results are likely to help prevent the effects of early-life seizures, which can include learning impairment and epilepsy, and will also advance the understanding of the synaptic mechanisms underlying developmental disabilities.
Dr. Timothy Bernard serves as the director of the CHC Pediatric Stroke Program, researching inflammation, coagulation, classification, treatments, and outcomes in childhood-onset arterial ischemic stroke. His research is funded through an NIH/NHLBI K23 award, as all as several international studies. He participates in several multi-center studies in childhood stoke, including the International Pediatric Stroke Study and the Thrombolyisis in Pediatric Stroke Study.
Dr. Richard Boada research has been focused on the identification of shared genetic, cognitive, and environmental factors that explain the comorbidity between speech, language, reading, and attentional disorders. He is currently involved in a multi-site study of reading and dyslexia in minority populations. He is also involved in studies looking at the cognitive sequelae of childhood stroke and Klinefelter syndrome, as well as the effects of pharmacological intervention for the amelioration of memory deficits in Down Syndrome.
Dr. Amy Brooks-Kayal is the Chief and Ponzio Family Chair of Pediatric Neurology at Children's Colorado, Professor of Pediatrics, Neurology and Pharmaceutical Sciences and Co-Director of the Translational Epilepsy Research Program at the University of Colorado Anschutz Medical Campus. She is also the interim Emphasis Area Leader for Neuroscience Research for Children's Hospital Colorado Research Institute. Dr. Brooks-Kayal's research program focuses on the development of new treatments for epilepsy by understanding the molecular and cellular mechanisms that result in development of epilepsy in order to develop new ways to prevent and treat this disorder. Her lab has identified changes in inhibitory neurotransmission, specifically GABA(A) receptor subunit expression, that may play a critical role in epilepsy development. Most recently, they have identified molecular signaling pathways, including BDNF and the CREB and JaK/STAT pathways, that regulate these receptor changes and shown that modulating these pathways can prevent these changes and inhibit epilepsy development. Learn more about Dr. Brooks-Kayal's Lab.
Dr. Kevin Chapman has a research interest in complex epilepsy and has a special interest in electrical status epilepticus in sleep (ESES). He is participating in multicenter research on status epilepticus and the utility of EEG in status epilepticus.
Dr. Abigail Collins’ research focuses on a variety of pediatric movement disorders.
Dr. Marco I. González is investigating the molecular bases of epilepsy development or epileptogenesis in order to get new insight into potential therapies that may help to prevent epilepsy before it starts.
Dr. Carolyn Green is investigating the tools and strategies to facilitate the specialist involvement to support family-centered community-based health care (AKA medical home or medical neighborhood) for children with chronic conditions, which includes excellent communication and care coordination among families, specialists and primary care providers.
Dr. Jennifer Janusz has research interests in the neurocognitive, behavioral, and emotional functioning of children with Neurofibromatosis Type 1.
Dr. Susan Koh has interests in pediatric epilepsy, especially in pediatric epilepsy surgery, ketogenic diet and vagal nerve stimulation. She is also interested in tuberous sclerosis.