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Barbara Davis Center for Childhood Diabetes - Research Funding


 

Genetic Determinants of Multi-Organ Autoimmunity in Type 1 Diabetes
Principal Investigator: Jennifer M. Barker, MD
Mentor: Marian J. Rewers, MD, PhD, MPH
Source: Juvenile Diabetes Research Foundation -11-2005-15
Amount: $675,000/yr
Term: 2005 - 2010

Pre-POINT: The Dose-Finding Study Phase of the POINT (Primary Oral/Intranasal Insulin Trial) Study
Principal Investigator: Jennifer M. Barker, MD
Source: Forschergruppe Diabetes e.V., Munich (Juvenile Diabetes Research Foundation Subcontract)
Amount: $74,527/yr
Term: 2006 - 2009

An Accuracy Evaluation of the Medtronic Diabetes Guardian RT Glucose Monitoring System in Pediatric Subjects with Type 1 Diabetes
Principal Investigator: H. Peter Chase, MD
Source: Medtronic Diabetes
Amount: $34,100
Term: 2005 - 2006

Ancillary Study to Evaluate the Effect of Insulin Pumps with Direct Integration of SMBG Hb
Principal Investigator: H. Peter Chase, MD
Source: Smiths Medical MD, Inc.
Amount: $55,125/yr
Term: 2004 - 2007

Development of Algorithms for a Prototype Closed Loop Insulin Pump (Track 2)
Principal Investigator: H. Peter Chase, MD
Source: Juvenile Diabetes Research Foundation/Jaeb Center for Health Research
Amount: $436,500
Term: 2006 - 2009

Effectiveness of Continuous Glucose Sensors in Type 1 Diabetes (Track 1)
Principal Investigator: H. Peter Chase, MD
Investigator: Rosanna V. Fiallo-Scharer, MD
Source: Juvenile Diabetes Research Foundation
Amount: $295,000/yr
Term: 2006 - 2009

Efficacy and Safety of Insulin Glulisine Compared with Insulin Lispro in Children and Adolescents with Type 1 Diabetes Mellitus
Principal Investigator: H. Peter Chase, MD
Source: Aventis Pharmaceuticals, Inc.
Amount: $48,000/yr
Term: 2004 - 2007

External Continuous Subcutaneous Infusion of Insulin Aspart (Novolog) vs. Insulin Lispro (Humalog)
Principal Investigator: H. Peter Chase, MD
Source: Novo Nordisk Pharmaceuticals, Inc.
Amount: $43,991/yr
Term: 2004 - 2006

Glucose Sensors in Children with Type 1 Diabetes
Principal Investigator: H. Peter Chase, MD
Source: NIH - 1 U10 HD041919
Amount: $352,000/yr
Term: 2001 - 2006

TrialNet - Prevention of Type 1 Diabetes
Co-Principal Investigator: H. Peter Chase, MD
Investigator: Peter A. Gottlieb, MD
Source: NIDDK, NIH - U01-DK60782
Amount: $993,520/yr
Term: 2001 - 2008

Active Tolerosomes: A Novel Therapy for Type 1 Diabetes
Principal Investigator: Howard W. Davidson, BSc, PhD
Source: NIDDK, NIH - R21 DK066043
Amount: $100,000/yr
Term: 2005 - 2007

Characterization of Autoantigen-Specific T Cell Receptors From PLNs
Principal Investigator: Howard W. Davidson, BSc, PhD
Co-Investigator: John C. Hutton, PhD
Co-Investigator: Roberto Gianani, MD
Source: Juvenile Diabetes Research Foundation - 25-2007-843
Amount: $100,000/yr
Term: 2007 - 2010

Autoimmunity Prevention Center - Project 2: Type 1A Diabetes: Expanding the Limits of Genetic Prediction
Principal Investigator: George S. Eisenbarth, MD, PhD
Co-Investigator: Pamela R. Fain, PhD
Source: NIAID, NIH - 5U19AI050864-080004
Amount: $249,807/yr
Term: 2006 - 2011

Benaroya Research Institute/UCD Autoimmune Cooperative Study Group
Principal Investigator: George S. Eisenbarth, MD, PhD
Source: NIDDK, NIH - 1 R01 DK62718 - U19 A11050864-06
Amount: $2,585,833/yr
Term: 2001 - 2011

Brehm Center Coalition
Principal Investigator: George S. Eisenbarth, MD, PhD
Source: University of Michigan
Amount: $250,000/yr
Term: 2007 - 2009

Challenging the One Model [NOD] One Peptide Etiology Diabetes
Principal Investigator: George S. Eisenbarth, MD, PhD
Source: Juvenile Diabetes Research Foundation - 1-2006-16
Amount: $50,000/yr
Term: 2005 - 2009

Collaborative Network for Clinical Research in Immune Tolerance - Administrative Core
Project Leader: George S. Eisenbarth, MD, PhD
Source: NIAID, NIH (UCSF Subcontract 3068SC)
Amount: $80,620/yr
Term: 2002 - 2009

Collaborative Network for Clinical Research in Immune Tolerance - Antibody Core
Project Leader: George S. Eisenbarth, MD, PhD
Source: NIAID, NIH - N01-A1-15416 (UCSF Subcontract 3109SC)
Amount: $154,516/yr
Term: 2002 - 2014

Core Autoantibody Determination Laboratory for Immune Tolerance Network
Principal Investigator: George S. Eisenbarth, MD, PhD
Source: NIAID, NIH - N01-AI-95380
Amount: $151,000/yr
Term: 1999 - 2006

The Environmental Determinants of Diabetes in the Young (TEDDY): Autoantibody Lab
Project Leader: George S. Eisenbarth, MD, PhD
Source: University of South Florida (Subcontract)
Amount: $210,769/yr
Term: 2004 - 2009

In Vivo Evaluation of a "Pathogenic" Insulin Peptide
Principal Investigator: George S. Eisenbarth, MD, PhD
Co-Investigator: Dirk Homann, MD, PhD
Source: NIH - 2R01 DK055969-10
Amount: $189,241/yr
Term: 1998 - 2010

In Vivo NOD Evaluation of a "Pathogenic" Insulin Peptide
Principal Investigator: George S. Eisenbarth, MD, PhD
Co-Investigator: Dirk Homann, MD, PhD
Source: NIH - 5R01 DK055969-07
Amount: $194,200/yr
Term: 1998 - 2006

Mentor-Based Postdoctoral Fellowship
Principal Investigator: George S. Eisenbarth, MD, PhD
Source: American Diabetes Association - 7-06-MN-17
Amount: $45,000/yr
Term: 2004 - 2010

Modeling and Detecting Pathogens of Islet Autoimmunity
Principal Investigator: George S. Eisenbarth, MD, PhD
Source: NIDDK, NIH - 1 R01 DK62718
Amount: $100,000/yr
Term: 2002 - 2006

Multiple Autoantigens/Multiple Epitopes of Type 1 Diabetes
Principal Investigator: George Eisenbarth, MD, PhD
Co-Investigator: Pamela R. Fain, PhD
Source: NIDDK, NIH - 2 R01 DK032083-26A1
Amount: $269,500/yr
Term: 2006 - 2011

Type 1 Diabetes Genetics Consortium Laboratory
Project Leader: George S. Eisenbarth, MD, PhD
Source: NIDDK, NIH - U01 DK062418 (Subcontract)
Amount: $66,516/yr
Term: 2003 - 2009

Type 1 Diabetes TrialNet, HLA
Principal Investigator: George S. Eisenbarth, MD, PhD
Source: NIDDK, NIH - U01-DK61055-01 (Autoantibody Laboratory Subcontract)
Amount: $918,647/yr
Term: 2002 - 2009

Virginia Mason/UCD Autoimmune Prevention Center
Principal Investigator: George S. Eisenbarth, MD, PhD
Source: NIDDK, NIH - 5U19AI050864-05
Amount: $100,000/yr
Term: 2001 - 2006

Ontologies and Biomedical Language Processing
Principal Investigator: Larry Hunter, PhD
Co-Investigator: George S. Eisenbarth, MD, PhD
Source: NIAID, NIH - R01 GM083649
Amount: $462,883/yr
Term: 2007 - 2008

Autosomal Dominant Polycystic Kidney Disease Human and Animal Resource Core
Principal Investigator: Pamela R. Fain, PhD
Source: PKD Foundation
Amount: $90,909/yr
Term: 2006 - 2007

Genetic Epidemiology of Lung Cancer Consortium
Principal Investigator: Pamela R. Fain, PhD
Source: University of Cincinnati (subcontract), National Cancer Institute, NIH, and SRS - 19633
Amount: $86,774/yr
Term: 2005 - 2010

Islet Cell Autoimmunity: Are Dizygotic Twins the Same as Siblings?
Principal Investigator: Pamela R. Fain, PhD
Source: American Diabetes Association 1-04-RA-23
Amount: $100,000/yr
Term: 2004 - 2007

Islet-Cell Autoimmunity: Are Dysgenic Twins the Same as Siblings? Effectiveness of Continuous Glucose Sensors in Type 1 Diabetes
Principal Investigators: Pamela R. Fain, PhD, and H. Peter Chase, MD
Source: Juvenile Diabetes Research Foundation/Jaeb Center for Health Research
Amount: $324,922/yr
Term: 2006 - 2009

Denver Autoimmune Center of Excellence
Basic Project 2: Genetic Analysis of Autoimmune Polyendocrine Syndrome-II

Principal Investigator: Michael Holers, MD
Project Leader: Richard A. Spritz, MD
Co-Investigator: Pamela R. Fain, PhD
Source: NIAID, NIH - U19 AI46374
Amount: $150,000/yr
Term: 2003 - 2009

International Consortium to Identify Susceptibility Genes for Generalized Vitiligo
Principal Investigator: Richard A. Spritz, MD
Co-Investigator: Pamela R. Fain, PhD
Source: NIAMS, NIH - 1 R01 AR056292-01
Amount: $945,559/yr
Term: 2008 - 2013

Mapping of Vitiligo Susceptibility Genes
Principal Investigator: Richard A. Spritz, MD
Co-Investigator: Pamela R. Fain, PhD
Source: NIH - 5 R01 AROH5584-06
Amount: $547,668/yr
Term: 2004 - 2009

Modifier Genes in Autosomal Dominant Polycystic Kidney Disease
Project 2: NIH Program Project

Principal Investigator: Robert Schrier, MD
Project Leader: Pamela R. Fain, PhD
Source: NIDDK, NIH - PO1 DK034039
Amount: $150,000/yr
Term: 2001 - 2008

Genetics Consortium in North America (T1DGC) Award
Principal Investigator: Rosanna V. Fiallo-Scharer, MD
Source: NIDDK, NIH - U01 DK3
Amount: $184,433/yr
Term: 2003 - 2009

Type 1 Diabetes Genetics Consortium
Principal Investigator: Rosanna V. Fiallo-Scharer, MD
Source: NIDDK, NIH - DK062418 (Subcontract)
Amount: $4,500/yr
Term: 2003 - 2008

Type 1 Genetics Consortium
Principal Investigator: Rosanna V. Fiallo-Scharer, MD
Source: Benaroya Research Institute at Virginia Mason (Subcontract)
Amount: $183,669/yr
Term: 2003 - 2006

Aventis HOE 901/4016
Principal Investigator: Satish K. Garg, MD
Co-Investigator: William E. Jackson, MD
Source: Quintiles/Aventis
Amount: $34,000/yr
Term: 2001 - 2006

Calibration Surveillance Protocol for Keynote (or its equivalent) Blood Glucose Monitoring System
Principal Investigator: Satish K. Garg, MD
Source: Agamatrix, Inc.
Amount: $25,000/yr
Term: 2007

Effect of Insulin Glulisine Compared to Insulin Aspart and Insulin Lispro when Administered by CSII
Principal Investigator: Satish K. Garg, MD
Source: Sanofi-Aventis
Amount: $60,000/yr
Term: 2007 - 2009

Exenatide in Type 2 Diabetes - Long-Term Use Study
Principal Investigator: Satish K. Garg, MD
Source: Amylin Pharmaceuticals
Amount: $3,150/yr
Term: 2004 - 2008

Glycemic Control and Prevention of Hypoglycemia in Intensively Treated Subjects with Type 1 Diabetes Using Accu-Check Advisor Insulin Guidance Software
Principal Investigator: Satish K. Garg, MD
Source: Roche Diagnostics Corporation
Amount: $573,300/yr
Term: 2005 - 2010

Glycemic Control and Prevention of Hypoglycemia Using Accu-Chek Advisor Insulin Guidance Software
Principal Investigator: Satish K. Garg, MD
Source: Roche Laboratories
Amount: $752,528/yr
Term: 2005 - 2007

Health Care Provider Study
Principal Investigator: Satish K. Garg, MD
Source: Johnson & Johnson
Amount: $12,800
Term: 2006 - 2007

Inhaled Insulin Student
Principal Investigator: Satish K. Garg, MD
Source: Novo Nordisk
Amount: $200,000/yr
Term: 2006 - 2010

IO Meter/Controller Human Factors and Clinical Accuracy Regulatory Study
Principal Investigator: Satish K. Garg, MD
Source: LifeScan, Inc.
Amount: $41,745/yr
Term: 2007 - 2008

Lantus and Apidra vs. Pre-Mix Insulin in Type 1 Diabetes
Principal Investigator: Satish K. Garg, MD
Source: Aventis
Amount: $132,493/yr
Term: 2005 - 2008

Lantus Plus Apidra MDI vs. Apidra MDI vs. Premix Insulin Treatment in Subjects with Diabetes Mellitus
Principal Investigator: Satish K. Garg, MD
Source: Quintiles/Aventis
Amount: $61,800/yr
Term: 2004 - 2008

Long-Term Study of Human Insulin Inhalation Powder in Type 1 Diabetes
Principal Investigator: Satish K. Garg, MD
Source: Eli Lilly & Company
Amount: $1,294,260/yr
Term: 2005 - 2010

Long-Term Study of Human Insulin Inhalation Powder vs. Injectable Insulin Phase 3 Study in Patients with Type 1 Diabetes
Principal Investigator: Satish K. Garg, MD
Source: Eli Lilly & Company
Amount: $142,130/yr
Term: 2006 - 2011

Markers and Mechanisms for Pre-Eclampsia in Women with Type 1 Diabetes
Principal Investigator: Satish K. Garg, MD
Source: Novo Nordisk Pharmaceuticals, Inc.
Amount: $15,000/yr
Term: 2005 - 2007

Navigator Study
Principal Investigator: Satish K. Garg, MD
Source: Abbott Laboratories
Amount: $81,000/yr
Term: 2006 - 2010

Noninvasive Glucose Monitor Testing Using the Critical Care Monitor in Subjects with Type 1 Diabetes
Principal Investigator: Satish K. Garg, MD
Source: Nostix
Amount: $44,604/yr
Term: 2005 - 2007

Novolog Mix Insulin in Combination with Metformin and Pioglitazone
Principal Investigator: Satish K. Garg, MD
Source: Novartis AG
Amount: $65,760/yr
Term: 2004 - 2008

Open-Label, Multicenter, Randomized, Parallel Group Study Comparing the Efficacy and Safety of Insulin Viaject and Regular Human Insulin in Patients with Type 1 Diabetes
Principal Investigator: Satish K. Garg, MD
Source: Biodel
Amount: $75,000/yr
Term: 2006 - 2010

A Pivotal Long-Term, Open-Label, Parallel Study of the Efficacy and Safety of Human Insulin Inhalation Powder in Patients with Type 1 Diabetes Mellitus
Principal Investigator: Satish K. Garg, MD
Source: Eli Lilly & Company
Amount: $1,294,260/yr
Term: 2005 - 2009

Pre-Eclampsia in Pregnant Women with Type 1 Diabetes
Principal Investigator: Satish K. Garg, MD
Source: Juvenile Diabetes Research Foundation
Amount: $89,000/yr
Term: 2004 - 2007

Prospective, Open-Label, Observational Study Evaluating Symlin® Injection Use in Insulin-Using Patients with Type 2 and Type 1 Diabetes Following Symlin® Introduction into the Marketplace
Principal Investigator: Satish K. Garg, MD
Source: Amylin Pharmaceuticals
Amount: $17,624/yr
Term: 2005 - 2008

Protocol for User Evaluation of the Performance of the AgaMatrix KeyNote Blood Glucose
Principal Investigator: Satish K. Garg, MD
Source: AgaMatrix, Inc.
Amount: $45,000/yr
Term: 2005 - 2007

Safety and Efficacy of the DexCom G2 Glucose Sensor in Patients with Diabetes Mellitus
Principal Investigator: Satish K. Garg, MD
Source: DexCom, Inc.
Amount: $400,000/yr
Term: 2004 - 2008

Short-Term Glucose Sensors
Principal Investigator: Satish K. Garg, MD
Source: DexCom, Inc.
Amount: $269,413/yr
Term: 2005 - 2010

Study to Evaluate Human Factors and Labeling Comprehension of the Symphony Insulin Delivery and Blood Glucose Monitor
Principal Investigator: Satish K. Garg, MD
Source: Animas
Amount: $38,115/yr
Term: 2007 - 2008

User Evaluation of AgaMatrix Keynote Blood Glucose Monitor
Principal Investigator: Satish K. Garg, MD
Source: Agamatrix, Inc.
Amount: $65,000/yr
Term: 2005 - 2007

Islet Autoantibody Core
Principal Investigator: Roberto Gianani, MD
Source: Juvenile Diabetes Research Foundation - 6-2007-477
Amount: $53,184/yr
Term: 2007-2010

Immunobiology of Pancreatic Islet Xenografting
Principal Investigator: Ronald G. Gill, PhD
Source: NIDDK, NIH - 5 R01 DK045773
Amount: $198,503/yr
Term: 1993 - 2006

Islet Cell Resources Facility at the University of Colorado Denver
Principal Investigator: Ronald G. Gill, PhD
Source: NIDDK, NIH - U42 RR016599
Amount: $663,156/yr
Term: 2001 - 2006

Reversal of Diabetes by Islet Transplantation
Principal Investigator: Ronald G. Gill, PhD
Source: NIDDK, NIH - R01 DK33470
Amount: $284,130/yr
Term: 1984 - 2007

Use of Hematopoietic Stem Cells for the Regulation of Autoimmune Diabetes
Principal Investigator: Ronald G. Gill, PhD
Source: NIDDK, NIH - R21 AI060349
Amount: $150,000/yr
Term: 2003 - 2006

Use of Hematopoietic Stem Cells for the Regulation of Autoimmune Diabetes
Principal Investigator: Ronald G. Gill, PhD
Source: Juvenile Diabetes Research Foundation - 1-2003-737
Amount: $144,656/yr
Term: 2005 - 2006

Denver Autoimmunity Center of Excellence
Project II: Complement in the Immunopathogenesis of Autoimmune Diabetes

Principal Investigator: V. Michael Holers, MD
Co-Investigator: Ronald G. Gill, PhD
Source: NIAID, NIH - U19 AI46374
Amount: $150,000/yr
Term: 2003 - 2008

B Cell ELISpot for the AntiCD20 Trial and Other TrialNet Studies: Laboratory Subcontract
Principal Investigator: Peter A. Gottlieb, MD
Co-Principal Investigator: Danny Zipris, PhD
Source: NIDDK, NIH - DK60782
Amount: $512,000/yr
Term: 2005 - 2008

Diabetes Prevention Trial-1 (Clinical Center Subcontract)
Principal Investigator: Peter A. Gottlieb, MD
Source: Juvenile Diabetes Foundation, American Diabetes Association, NIH - 5 U01 DK60782
Amount: $377,395/yr
Term: 2001 - 2008

Diabetes Prevention Trial-1/TrialNet
Principal Investigator: Peter A. Gottlieb, MD
Source: NIDDK, NIH - DK60782
Amount: $555,600/yr
Term: 2001 - 2009

North American Cytokine ELISpot Laboratory
Principal Investigator: Peter A. Gottlieb, MD
Source: GWU TrialNet (Subcontract)
Amount: $200,000/yr
Term: 2005 - 2007

ProInsulin DNA Vaccine Trial for Recent Onset Type 1 Diabetes Investigation of Antigen Therapy, BHT-3021: Clinical Portion
Principal Investigator: Peter A. Gottlieb, MD
Source: BayHill Therapeutics
Amount: $233,500/yr
Term: 2006 - 2009

ProInsulin DNA Vaccine Trial for Recent Onset Type 1 Diabetes Monitoring of T Cell Responses to ProInsulin Vaccine
Principal Investigator: Peter A. Gottlieb, MD
Source: BayHill Therapeutics - BHT-3021
Amount: $407,600/yr
Term: 2006 - 2009

Role of Regulatory CD4+ and CD25+ T Cells in Diabetes
Principal Investigator: Peter A. Gottlieb, MD
Source: Brigham and Women's Hospital
Amount: $29,000/yr
Term: 2005 - 2007

RT4 and TTEDD Trials of Anti-CD3 in Recent Onset Type 1 Diabetes Mellitus Phase 2 Clinical Study Evaluating an Antibody Therapy
Principal Investigator: Peter A. Gottlieb, MD
Source: TolRx
Amount: $125,000/yr
Term: 2006 - 2008

Tolerability and Safety of Multiple-Dose Regimen of TRX4 Anti-CD3 Monoclonal Antibody Type 1 Diabetes Mellitus
Principal Investigator: Peter A. Gottlieb, MD
Source: TolerRx
Amount: $24,572/yr
Term: 2005 - 2007

Treatment with hOKT3g1 (Ala-Ala) in T1DM
Principal Investigator: Peter A. Gottlieb, MD
Source: Immune Tolerance Network
Amount: $116,094/yr
Term: 2005 - 2007

Treatment with hOKT3g1 (Ala-Ala) in T1DM ITN027AI (Phase II)
Principal Investigator: Kevan C. Herold, MD
Investigator: Peter A. Gottlieb, MD (Subcontract with ITN #369SC)
Source: Immune Tolerance Network - N01-AI-15416
Amount: $406,260/yr
Term: 2005 - 2009

TrialNet - Prevention of Type 1 Diabetes
Investigator: Peter A. Gottlieb, MD
Co-Principal Investigator: H. Peter Chase, MD
Source: NIDDK, NIH - U01-DK60782
Amount: $993,520/yr
Term: 2001 - 2008

NIH Autoimmunity Core A
Principal Investigator: V. Michael Holers, MD
Co-Investigator: Peter A. Gottlieb, MD
Source: NIAID, NIH - U19 AI46374
Amount: $84,409/yr
Term: 1999 - 2008

Proteomics Analysis of T Cell Autoantigens in T1D2
Principal Investigator: Kathryn Haskins, PhD
Co-Investigators: John C. Hutton, PhD, and Howard W. Davidson, BSc, PhD
Source: NIH - R21 AI065355
Amount: $200,000/yr
Term: 2004 - 2006

Chemokine Signatures in Pathogenesis and Prevention of Type 1 Diabetes
Principal Investigator: Dirk Homann, MD, PhD
Source: Juvenile Diabetes Research Foundation - CDA - 2-2007-240
Amount: $150,000/yr
Term: 2007 - 2012

Maturation of Established Antiviral CS8+T Cell Memory
Principal Investigator: Dirk Homann, MD, PhD
Source: NIH - 1R21 AG026518-01
Amount: $150,000/yr
Term: 2005 - 2007

Active Tolerosomes: A Novel Therapy for Type 1 Diabetes
Principal Investigator: John C. Hutton, PhD
Source: American Diabetes Association - 7-06-MI-03
Amount: $45,000/yr
Term: 2006 - 2009

ADA Mentor-Based Postdoctoral Fellowship
Principal Investigator: John C. Hutton, PhD
Source: American Diabetes Association - 7-04-MN-19
Amount: $45,000/yr
Term: 2004 - 2008

The BDC-JDRF Autoimmunity Prevention Center
Principal Investigator: John C. Hutton, PhD
Project Leader: George S. Eisenbarth, MD, PhD
Source: Juvenile Diabetes Research Foundation (JDRF) - 4-2007-1056
Amount: $973,354/yr
Term: 2008 - 2012

  • Project 1: Genetic Validation of TCR Conserved Sequence Criticality
    Project Principal Investigator: George S. Eisenbarth, MD, PhD
    Amount: $146,503/yr

  • Project 5: Humoral Autoreactivity to Novel Human Diabetes Autoantigen Slc30A8
    Project Principal Investigator: John C. Hutton, PhD
    Amount: $169,771/yr

  • Project 6: T Cell Immunity to the Novel Human T1D Autoantigen Slc30A8
    Project Principal Investigator: Howard W. Davidson, BSc, PhD
    Amount: $171,087/yr

  • Core A: Autoimmunity Analysis Core (Immune Response Monitoring)
    Project Principal Investigator: Danny Zipris, PhD
    Co-Principal Investigator: Peter A. Gottlieb, MD
    Amount: $162,598/yr

  • Core B: Administrative Core
    Project Principal Investigator: John C. Hutton, PhD
    Amount: $87,904/yr

Cloning of Molecular Targets of CMI in Type 1 Diabetes
Principal Investigator: John C. Hutton, PhD
Co-Investigator: Howard W. Davidson, BSc, PhD
Source: NIH - R01 DK052068
Amount: $225,000/yr
Term: 2005 - 2010

Cloning of Molecular Targets of CMI in Type 1 Diabetes
Principal Investigator: John C. Hutton, PhD
Co-Investigator: Peter A. Gottlieb, MD
Source: NIDDK, NIH - R01 DK052068-05A1
Amount: $49,000/yr
Term: 2004 - 2009

IGRP Knockout Mouse - Collaboration between Vanderbilt University and Barbara Davis Center Focused on IGRP as Major Autoantigen in the Mouse Non-Obese Diabetic Model of Type 1 Diabetes
Principal Investigator: John C. Hutton, PhD
Source: NIH - R01 DK076027-01 (Vanderbilt University Subcontract)
Amount: $150,000/yr
Term: 2006 - 2010

Islet G6Pase-Related Protein: A Novel Cell-Specific Target for T Cell Mediated Autoimmunity in Type 1 Diabetes
Principal Investigator: John C. Hutton, PhD
Co-Investigator: Howard W. Davidson, BSc, PhD
Source: American Diabetes Association - 1-04-RA-44
Amount: $86,957/yr
Term: 2004 - 2006

Mentor-Based Postdoctoral Fellowship Program
Principal Investigator: John C. Hutton, PhD
Source: American Diabetes Association - 7-04-MN-19
Amount: $45,000/yr
Term: 2000 - 2008

A Novel Developmental Surface Marker of Pancreatic ß Cells
Principal Investigator: John C. Hutton, PhD
Source: NIH - U01 DK072473 (Vanderbilt University Subcontract)
Amount: $62,500/yr
Term: 2006 - 2009

Study to Establish the Role of Phogrin, an Islet Cell Secretory Granule Protein Tyrosine Phosphatase in the Autoimmune Process of Type 1 Diabetes
Principal Investigator: John C. Hutton, PhD
Source: American Diabetes Association
Amount: $45,000/yr
Term: 2000 - 2008

Tryptophan Metabolism in Type 1 Diabetes
Principal Investigator: John C. Hutton, PhD
Co-Investigator: Howard W. Davidson, BSc, PhD
Source: Juvenile Diabetes Research Foundation - 1-2005-145
Amount: $150,000/yr
Term: 2005 - 2008

Tryptophan Metabolism in Type 1 Diabetes Investigation of the Role of Enzymes of Tryptophan Metabolism in the Pathogenesis of Type 1 Diabetes, Notably Gene Expression Changes in Indoleamine 2, 3 Dioxygenase
Principal Investigator: John C. Hutton, PhD
Source: Juvenile Diabetes Research Foundation
Amount: $150,000/yr
Term: 2005 - 2008

UCD Diabetes and Endocrinology Research Center (DERC)
Principal Investigator: John C. Hutton, PhD
Project Leader: George S. Eisenbarth, MD, PhD
Co-Investigators:
Howard W. Davidson, BSc, PhD: Molecular and Vector Cores
Danny Zipris, PhD: Animal and Islet Cores
Roberto Gianani, MD: Histology Core
Suparna Sarkar, MBBS, PhD: Bioinformatics
Marian J. Rewers, MD, PhD, MPH: Clinical/Information Tech Core
Dirk Homann, MD, PhD: Cytometry Core
Source: NIDDK, NIH - P30 DK57516
Amount: $1,249,431/yr
Term: 2005 - 2010

Verify Cloning of Molecular Targets of CMI in Type 1 Diabetes
Principal Investigator: John C. Hutton, PhD
Source: NIH - R01 DK 052068-05A1
Amount: $225,000/yr
Term: 2005 - 2010

The Role of the Zinc Transporter, ZnT8, in Pancreatic Beta Cell Biology
Principal Investigator: Leah Sheridan, PhD (Postdoctoral Fellow)
Co-Principal Investigator and Mentor: John C. Hutton, PhD
Source: Juvenile Diabetes Research Foundation
Amount: $47,296/yr
Term: 2008 - 2010

Systems Biology of the Beta Cell
Principal Investigator: Leroy Hood, PhD
Consultant: John C. Hutton, PhD
Source: Juvenile Diabetes Research Foundation
Amount: $45,454/yr
Term: 2008 - 2013

Molecular Mechanism of FGF10 Signaling in Pancreatic Development
Principal Investigator: Jan Jensen, MSc, PhD
Source: NIDDK, NIH - R01 DK070636-01A1
Amount: $225,000/yr
Term: 2005 - 2010

Morphogenetic Control of ß Cell Specification
Principal Investigator: Jan Jensen, MSc, PhD
Source: American Diabetes Association - ADA 7-01-CD-11
Amount: $193,599/yr
Term: 2001 - 2006

Diabetes Research for Pediatric Endocrinologists
Principal Investigator: Georgeanna J. Klingensmith, MD
Source: NIDDK, NIH - 5 K12 DK063722-03
Amount: $288,963/yr
Term: 2002 - 2010

In-Clinic and Home-Use of the AVATAR Blood Glucose Monitoring System in Children and Young Adults
Principal Investigator: Georgeanna J. Klingensmith, MD
Source: Bayer Healthcare Pharmaceuticals
Amount: $37,522/yr
Term: 2008 - 2009

Training Programs in Diabetes Research for Pediatric Endocrinologists
Principal Investigator: Georgeanna J. Klingensmith, MD
Source: NIDDK, NIH - 2 T32 DK063687
Amount: $208,733/yr
Term: 2002 - 2012

SEARCH for Diabetes in Youth 2: Colorado Center Multicenter Study to Determine the Prevalence and Incidence of Type 1 and Type 2 Diabetes in Children and Adolescents Under the Age of 20
Principal Investigator: Dana Dabelea, MD, PhD
Co-Investigator: Georgeanna J. Klingensmith, MD
Source: National Center for Chronic Disease Prevention and Health Promotion, CDC
Amount: $514,887/yr
Term: 2005 - 2010

Cardiovascular Disease in Type 1 Diabetes Mellitus: Young Adults to Adolescents
Principal Investigator: David M. Maahs, MD
Mentor: Marian J. Rewers, MD, PhD, MPH
Source: NIH - K23 DK075360-01A1
Amount: $132,000/yr
Term: 2007 - 2012

Cardiovascular Disease in Type 1 Diabetes Mellitus: Young Adults to Adolescents
Principal Investigator: David M. Maahs, MD
Source: Diabetes and Endocrinology Research Core, Pilot and Feasibility Grant
Amount: $62,500
Term: 2006 - 2007

Carbohydrate Counting in Adolescents with Type 1 Diabetes: Education to Intervention
Principal Investigator: David M. Maahs, MD
Source: American Dietetic Association Foundation
Amount: $10,000/yr
Term: 2008-2010

Clinical Trial of Zocor and Vytorin in Adolescents with Type 1 Diabetes
Principal Investigator: David M. Maahs, MD
Co-Principal Investigator: R. Paul Wadwa, MD
Source: Merck Medical School Grant
Amount: $71,878/yr
Term: 2006 - 2009

Dissecting a Primary Insulin Peptide from Thymus to Islet
Principal Investigator: Maki Nakayama, MD
Source: Juvenile Diabetes Research Foundation - 44-2008-913
Amount: $76,946/yr
Term: 2008 - 2009

Dynamic Surveying of T Cell Repertoire Targeting Pancreatic Beta Cells
Principal Investigator: Maki Nakayama, MD
Source: Juvenile Diabetes Research Foundation - 10-2006-51
Amount: $29,309/yr
Term: 2006 - 2008

Structure Peptide/Conserved T Cell Receptor Determining Diabetes
Principal Investigator: Maki Nakayama, MD
Source: NIH - K99-DK080885
Amount: $70,800/yr
Term: 2008 - 2010

Viability Assay for Human Islet Transplantation
Principal Investigator: Mark R. Nicolls, MD
Co-Investigator: Ronald G. Gill, PhD
Source: NIH - R21 DK70203
Amount: $250,000/yr
Term: 2004 - 2006

The Environmental Determinants of Diabetes in the Young (TEDDY): Nutritional Supplement
Principal Investigator: Jill Norris, PhD
Source: University South Florida
Amount: $74,000/yr
Term: 2004 - 2009

The Mechanism of CD40 T Cell Dependent Acute Cardiac Allograft Rejection
Principal Investigator: Biagio A. Pietra, MD
Co-Investigator: Ronald G. Gill, PhD
Source: NIH - R01 HL67976
Amount: $225,000/yr
Term: 2001 - 2006

Colorado CVD Prevention Program in Children and Adults with Type 1 Diabetes
Principal Investigator: Marian J. Rewers, MD, PhD, MPH
Source: Colorado Department of Public Health and Environment
Amount: $204,253/yr
Term: 2007 - 2010

Common Mechanisms of Autoimmune Diseases
Principal Investigator: Marian J. Rewers, MD, PhD, MPH
Source: Juvenile Diabetes Research Foundation
Amount: $200,000/yr
Term: 2008 - 2011

Determinants of Accelerated Cardiovascular Disease in Type 1 Diabetes
Principal Investigator: Marian J. Rewers, MD, PhD, MPH
Source: NHLBI, NIH - RO1 HL079611
Amount: $1,536,537/yr
Term: 2004 - 2009

The Environmental Determinants of Diabetes in the Young (TEDDY)
Principal Investigator: Marian J. Rewers, MD, PhD, MPH
Co-Investigator: Georgeanna J. Klingensmith, MD
Source: NIDDK, NIH - U01 DK63821
Amount: $2,080,000/yr
Term: 2003 - 2012

Genetic and Environmental Causes of Celiac Disease
Principal Investigator: Marian J. Rewers, MD, PhD, MPH
Co-Investigator: Edward J. Hoffenberg, MD
Source: NIDDK, NIH - 2 RO1 DK050979-11
Amount: $205,000/yr
Term: 1995 - 2011

Immunogenic Pathways to T1D and Other Autoimmune Diseases
Principal Investigator: Marian J. Rewers, MD, PhD, MPH
Source: Juvenile Diabetes Research Foundation - 33-2008-396
Amount: $199,875/yr
Term: 2008 - 2011

Mentored Fellowship in Cardiovascular Disease and Diabetes
Mentor: Marian J. Rewers, MD, PhD, MPH
Source: American Diabetes Association
Amount: $45,000/yr
Term: 2006 - 2008

Microarray Subcontract
Principal Investigator: Marian J. Rewers, MD, PhD, MPH
Source: NIDDK, NIH - 5 R33 DK069878 (Medical College of Georgia)
Amount: $46,000/yr
Term: 2003 - 2009

Research into the Immunogenetics of Type 1 Diabetes
Mentor: Marian J. Rewers, MD, PhD, MPH
Source: O'Brien Fellowship, Children’s Diabetes Foundation
Amount: $40,000/yr
Term: 2007 - 2009

Subclinical Heart Diseases in Insulin-Dependent Diabetes: Coronary Artery Calcification in Type 1 Diabetes
Principal Investigator: Marian J. Rewers, MD, PhD, MPH
Source: NHLBI, NIH - R01 HL61753
Amount: $474,288/yr
Term: 1999 - 2009

Nutritional Etiology of Prediabetic Autoimmunity
Principal Investigator: Jill Norris, PhD
Investigator: Marian J. Rewers, MD, PhD, MPH
Co-Investigator: Ronald J. Sokol, MD
Source: NIDDK, NIH - R01 DK049654
Amount: $350,000/yr
Term: 1997 - 2011

Functional Assessment of Novel T1D Autoantigen SLC30A8 in Human Islets
Principal Investigator: Suparna Sarkar, MBBS, PhD
Source: NIH/NIDDK DERC Pilot and Feasibility (NIH P30 DK57516)
Amount: $50,000
Term: 2008 - 2009

Indoleamine 2, 3 Dioxygenase Signaling and Function in Type 1 Diabetes
Principal Investigator: Suparna Sarkar, MBBS, PhD
Source: NIH - K01-DK080193-02
Amount: $112,035/yr
Term: 2007 - 2010

Novel Biomarkers of Pancreatic Beta Cell Neogenesis
Principal Investigator: Suparna Sarkar, MBBS, PhD
Source: Juvenile Diabetes Research Foundation - 1-2008-1021
Amount: $249,968
Term: 2008 - 2009

A Multicenter Analysis of Children and Adolescents to Determine the Risk of Nephropathy in Types 1 and 2 Diabetes, the Efficacy of Treatment, and the Associated Risk Factors
Principal Investigator: Robert H. Slover II, MD
Source: Boehringer Ingelheim
Amount: $110,000/yr
Term: 2006 - 2008

A Prospective, Randomized, Two-Arm Study to Compare the Efficacy of the MiniMed Paradigm Real-Time System Versus Multiple Daily Injection in Subjects with Type 1 Diabetes Mellitus Naive to Insulin Pump Therapy (Star 3)
Principal Investigator: Robert H. Slover II, MD
Source: Medtronic Diabetes
Amount: $396,000/yr
Term: 2007 - 2010

Determinants of Macrovascular Disease in Adolescents with Type 1 Diabetes
Principal Investigator: R. Paul Wadwa, MD
Mentor: Marian J. Rewers, MD, PhD, MPH
Source: Juvenile Diabetes Research Foundation
Amount: $150,000/yr
Term: 2007 - 2012

Treatment Alternatives in Pediatric Type 2 Diabetes and Population-Based Prevention Strategies
Principal Investigator: Philip S. Zeitler, MD, PhD
Co-Investigators: Georgeanna J. Klingensmith, MD, and Nancy F. Krebs, MD
Source: NIDDK, NIH - 5U01 DK61242
Amount: $691,820/yr
Term: 2002 - 2011

Specific Vbeta T Cell Receptor Targeting of Insulin B:9-23
Principal Investigator: Li Zhang, MD, PhD
Source: Juvenile Diabetes Research Foundation - 3-2008-107
Amount: $47,296/yr
Term: 2008 - 2010

Innate Immunity in Diabetes
Principal Investigator: Danny Zipris, PhD
Source: Juvenile Diabetes Research Foundation
Amount: $50,000/yr
Term: 2007 - 2008

Mechanisms of TLR-Induced Autoimmune Diabetes
Principal Investigator: Danny Zipris, PhD
Source: Juvenile Diabetes Research Foundation - 1-2006-584
Amount: $165,000/yr
Term: 2007-2010

Novel High-Throughput DNA Sequencing for Addressing the Role of Viruses in T1D
Principal Investigator: Danny Zipris, PhD
Source: Juvenile Diabetes Research Foundation
Amount: $75,000/yr
Term: 2008 - 2009

Role of Innate Immunity in Human Type 2 Diabetes
Principal Investigator: Danny Zipris, PhD
Source: Juvenile Diabetes Research Foundation - 5-2008-224
Amount: $110,000/yr
Term: 2008 - 2011

Role of Innate Immunity in Virus-Induced Autoimmune Diabetes
Principal Investigator: Danny Zipris, PhD
Source: Juvenile Diabetes Research Foundation - 1-2006-745
Amount: $165,000/yr
Term: 2007 - 2010

Glucose Sensors in Children with Type 1 Diabetes
Principal Investigator: H. Peter Chase, MD
Source: National Institutes of Health - 1 U10 HD041919
Amount: $352,000/yr
Term: 2001-2006

Efficacy and Safety of Insulin Glulisine Compared with Insulin Lispro in Children and Adolescents with Type 1 Diabetes Mellitus
Principal Investigator: H. Peter Chase, MD
Source: Aventis Pharmaceuticals Inc.
Amount: $48,000
Term: 2004-2007

External Continuous Subcutaneous Infusion of Insulin Aspart (Novolog) vs. Insulin Lispro (Humalog)
Principal Investigator: H. Peter Chase, MD
Source: Novo Nordisk Pharmaceuticals, Inc.
Amount: $43,991
Term: 2004-2006

An Accuracy Evaluation of the Medtronic Diabetes Guardian RT Glucose Monitoring System in Pediatric Subjects with Type 1 Diabetes
Principal Investigator: H. Peter Chase, MD
Source: Medtronic Diabetes
Amount: $34,100
Term: 2005-2006

Ancillary Study to Evaluate the Effect of Insulin Pumps with Direct Integration of SMBG Hb
Principal Investigator: H. Peter Chase, MD
Source: Smiths Medical MD, Inc.
Amount: $55,125
Term: 2004-2007

Active Tolerosomes, a Novel Therapy for Type 1 Diabetes
Principal Investigator: Howard Davidson, BSc, PhD
Source: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases - R21 DK066043
Amount: $100,000/yr
Term: 2005-2007

Antibodies to Recombinant Autoantigens: Prediction/Immunogenetics
Principal Investigator: George S. Eisenbarth, MD, PhD
Source: National Institutes of Health, National Institute of Allergy and Infectious Diseases - 2 R01 AI39213-06
Amount: $202,500
Term: 2001-2005

Autoimmunity Prevention Center
Principal Investigator: George S. Eisenbarth, MD, PhD
Source: National Institutes of Health, National Institute of Allergy and Infectious Diseases
Amount: $5,012,089
Term: 2001-2005

Core Autoantibody Determination Laboratory for Immune Tolerance Network
Principal Investigator: George S. Eisenbarth, MD, PhD
Source: National Institutes of Health, National Institute of Allergy and Infectious Diseases - N01-AI-95380
Amount: $151,000/yr
Term: 1999-2006

Diabetes and Endocrinology Research Center
Principal Investigator: John Hutton, PhD
Co-Investigator: George S. Eisenbarth, MD, PhD
Source: National Institutes of Health - P30 DK57516
Amount: $1,249,431
Term: 2005-2010

In Vivo NOD Evaluation of a "Pathogenic" Insulin Peptide
Principal Investigator: George S. Eisenbarth, MD, PhD
Co-Investigator: Dirk Homann, MD, PhD
Source: National Institutes of Health - R01 DK55969
Amount: $189,241/yr
Term: 1998-2006

Mentor-Based Fellowship
Principal Investigator: George S. Eisenbarth, MD, PhD
Source: American Diabetes Association
Amount: $45,000/yr
Term: 1998-2005

Modeling and Detecting Pathogens of Islet Autoimmunity
Principal Investigator: George S. Eisenbarth, MD, PhD
Source: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases - 1 R01 DK62718
Amount: $100,000/yr
Term: 2002-2006

Multiple Autoantigens/Multiple Epitopes of Pre-Type I Diabetes Mellitus
Principal Investigator: George S. Eisenbarth, MD, PhD
Source: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases - 2 R01 DK32083-20A2
Amount: $166,250/yr
Term: 2001-2005

Type 1 Diabetes TrialNet, HLA (Autoantibody Laboratory Subcontract)
Principal Investigator: George S. Eisenbarth, MD, PhD
Source: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases - U01-DK61055-01
Amount: $363,820
Term: 2002-2008

Immunogenetics of Type 1 Diabetes in a Bedouin Arab Family
Principal Investigator: Pamela R. Fain, PhD
Source: National Institutes of Health - RO1 DK57538
Amount: $275,000/yr
Term: 2000-2005

Islet-Cell Autoimmunity: Are Dizgotic Twins the Same as Siblings?
Principal Investigator: Pamela R. Fain, PhD
Source: American Diabetes Association - 1-04-RA-23
Term: 2004-2006

Type 1 Genetics Consortium (Subcontract)
Principal Investigator: Rosanna V. Fiallo-Scharer, MD
Source: Benaroya Research Institute at Virginia Mason
Amount: $183,669
Term: 2003-2006

Aventis HOE 901/4016
Principal Investigator: Satish K. Garg, MD
Co-Investigator: William E. Jackson, MD
Source: Quintiles/Aventis
Amount: $34,000
Term: 2001-2006

Lantus plus Apidra MDI vs. Apidra MDI vs. Premix Insulin Treatment in Subjects with Diabetes Mellitus
Principal Investigator: Satish K. Garg, MD
Source: Quintiles/Aventis
Amount: $61,800
Term: 2004-2008

A Pivotal Long-Term, Open-Label, Parallel Study of the Efficacy and Safety of Human Insulin Inhalation Powder in Patients with Type 1 Diabetes Mellitus
Principal Investigator: Satish K. Garg, MD
Source: Eli Lilly & Company
Amount: $1,294,260
Term: 2005-2009

Glycemic Control and Prevention of Hypoglycemia in Intensively Treated Subjects with Type 1 Diabetes Using Accu-Check Advisor Insulin Guidance Software
Principal Investigator: Satish K. Garg, MD
Source: Roche Diagnostics Corporation
Amount: $573,300
Term: 2005-2010

Safety and Efficacy of the DexCom G2 Glucose Sensor in Patients with Diabetes Mellitus
Principal Investigator: Satish K. Garg, MD
Source: DexCom, Inc.
Amount: $400,000
Term: 2004-2008

Markers and Mechanisms for Pre-Eclampsia in Women with Type 1 Diabetes
Principal Investigator: Satish K. Garg, MD
Source: NovoNordisk
Amount: $15,000
Term: 2005-2007

No Invasive Glucose Monitor Testing Using the Critical Care Monitor in Subjects with Type 1 Diabetes
Principal Investigator: Satish K. Garg, MD
Source: Nostix
Amount: $44,600
Term: 2005-2007

Protocol for User Evaluation of the Performance of the AgaMatrix KeyNote Blood Glucose
Principal Investigator: Satish K. Garg, MD
Source: AgaMatrix
Amount: $45,000
Term: 2005-2007

Immunobiology of Pancreatic Islet Xenografting
Principal Investigator: Ronald G. Gill, PhD
Source: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases - 5 R01 DK045773
Amount: $198,503/yr
Term: 1993-2006

Islet Cell Resources (ICR) Facility at the University of Colorado Denver
Principal Investigator: Ronald G. Gill, PhD
Source: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases - U42 RR016599
Amount: $663,156/yr
Term: 2001-2006

Reversal of Diabetes by Islet Transplantation
Principal Investigator: Ronald G. Gill, PhD
Source: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases - R01 DK33470
Amount: $284,130
Term: 1984-2007

T-Cell Mediated Injury to Islet Allografts
Principal Investigator: Ronald G. Gill, PhD
Source: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases - R01 DK55333
Amount: $143,568/yr
Term: 1998-2005

Use of Hematopoietic Stem Cells for the Regulation of Autoimmune Diabetes
Principal Investigator: Ronald G. Gill, PhD
Source: Juvenile Diabetes Research Foundation, 1-2003-737
Amount: $144,656/yr
Term: 2005-2006

Use of Hematopoietic Stem Cells for the Regulation of Autoimmune Diabetes
Principal Investigator: Ronald G. Gill, PhD
Source: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases - R21 AI060349
Amount: $150,000/yr
Term: 2003-2006

Diabetes Prevention Trial-1 (Clinical Center Subcontract)
Principal Investigator: Peter A. Gottlieb, MD
Source: National Institutes of Health, Juvenile Diabetes Foundation, American Diabetes Association - 5 U01 DK60782
Amount: $377,395/yr
Term: 2001-2008

Treatment with hOKT3g1 (Ala-Ala) in T1DM
Principal Investigator: Peter A. Gottlieb, MD
Source: ITN/Immune Tolerance Network
Amount: $116,094
Term: 2005-2007

North American Cytokine ELISpot Laboratory
Principal Investigator: Peter A. Gottlieb, MD
Source: National Institutes of Health
Amount: $200,000/yr
Term: 2005-2007

Role of Regulatory CD4+ and CD25+ T-Cells in Diabetes
Principal Investigator: Peter A. Gottlieb, MD
Source: Brigham and Women's Hospital
Amount: $29,000/yr
Term: 2005-2007

Tolerability and Safety of Multiple-Dose Regimen of TRX4 Anti-CD3 Monoclonal Antibody Type 1 Diabetes Mellitus
Principal Investigator: Peter A. Gottlieb, MD
Source: TolerRx
Amount: $24,572
Term: 2005-2007

Proteomics Analysis of T-Cell Autoantigens in T1D2
Principal Investigator: Kathryn Haskins, PhD
Co-Investigators: John Hutton, PhD, and Howard Davidson, BSc, PhD
Source: National Institutes of Health - R21 AI065355
Amount: $200,000/yr
Term: 2004-2006

Denver Autoimmunity Center of Excellence
Project II: Complement in the Immunopathogenesis of Autoimmune Diabetes

Principal Investigator: V. Michael Holers, MD
Co-Investigator: Ronald G. Gill, PhD
Source: National Institutes of Health, National Institute of Allergy and Infectious Diseases - U19 AI46374
Amount: $150,000/yr
Term: 2003-2008

Denver Autoimmunity Center of Excellence
Principal Investigator: V. Michael Holers, MD
Basic Project III: Genetic Analysis of Autoimmune Polyendocrine Syndrome-II
Principal Investigator: Richard A. Spritz, MD
Co-Investigator: Pamela R. Fain, PhD
Source: National Institutes of Health, National Institute of Allergy and Infectious Diseases - U19 AI46374
Amount: $150,000/yr
Term: 2003-2008

Maturation of Established Antiviral CD8 T-Cell Memory
Principal Investigator: Dirk Homann, MD, PhD
Source: National Institutes of Health - R21 AG026518
Amount: $125,000/yr
Term: 2005-2007

Cloning of Molecular Targets of CMI in Type 1 Diabetes
Principal Investigator: John Hutton, PhD
Co-Investigator: Howard Davidson, BSc, PhD
Source: National Institutes of Health - R01 DK052068
Amount: $225,000/yr
Term: 2005-2010

Development and Regeneration of the Endocrine Pancreas
Principal Investigator: John Hutton, PhD
Co-Investigator: Jan C. Jensen, MSc, PhD
Source: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases - U19 DK61248
Amount: $957,037/yr
Term: 2001-2005

Diabetes and Endocrinology Research Center
Principal Investigator: John Hutton, PhD
Co-Investigators: Ronald G. Gill, PhD, Howard Davidson, BSc, PhD, and Dirk Homann, MD, PhD
Source: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases - P30 DK57516
Amount: $972,233/yr
Term: 2000-2010

Islet G6Pase-Related Protein: A Novel -cell Specific Target for T-Cell Mediated Autoimmunity in Type 1 Diabetes
Principal Investigator: John Hutton, PhD
Co-Investigator: Howard Davidson, BSc, PhD
Source: American Diabetes Association - 1-04-RA-44
Amount: $86,957/yr
Term: 2004-2006

Mentor-Based Postdoctoral Fellowship Program
Principal Investigator: John Hutton, PhD
Source: American Diabetes Association - 7-04-MN-19
Amount: $45,000/yr
Term: 2000-2008

Tryptophan Metabolism in Type 1 Diabetes
Principal Investigator: John Hutton, PhD
Co-Investigator: Howard Davidson, BSc, PhD
Source: Juvenile Diabetes Research Foundation - 1-2005-145
Amount: $150,000/yr
Term: 2005-2008

Open-Label Treatment for Patients Completing Study B7A-MC-MBMC
Principal Investigator: William Jackson, MD
Source: Eli Lilly and Company
Amount: $39,834
Term: 2006-2009

Molecular Mechanism of FGF10 Signaling in Pancreatic Development
Principal Investigator: Jan Jensen, MSc, PhD
Source: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases - R01 DK070636-01A1
Amount: $225,000/yr
Term: 2005-2010

Morphogenetic Control of ß-cell Specification
Principal Investigator: Jan Jensen, MSc, PhD
Source: American Diabetes Association - ADA 7-01-CD-11
Amount: $193,599/yr
Term: 2001-2006

Studies Investigating the Role of Mybl2 in B-Cells
Principal Investigator: Jan Jensen, MSc, PhD
Source: Juvenile Diabetes Research Foundation - JDRF 5-2005-914
Amount: $100,000/yr
Term: 2005-2006

Diabetes Research for Pediatric Endocrinologists (K12) and Fellows Training Grant (T32)
Principal Investigator: Georgeanna J. Klingensmith, MD
Source: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases - 5 K12 DK063722-03 and 5 T32 DK063687-03
Amount: $288,963/yr (K12); $174,996/yr (T32)
Term: 2002-2007

Cell Cycle Inhibition in Systemic Autoimmunity
Principal Investigator: Dwight Kono, MD
Co-Investigator: Dirk Homman, MD, PhD
Source: National Institutes of Health - R01AI059777
Amount: $1,000,000
Term: 2005-2010

Molecular Epidemiology of Dilated Cardiomyopathy
Principal Investigator: Luisa Mestroni, MD
Co-Investigator: Pamela R. Fain, PhD
Source: National Institutes of Health, National Heart, Lung and Blood Institute - RO1 HL69071
Amount: $494,290/yr
Term: 2001-2005

Viability Assay for Human Islet Transplantation
Principal Investigator: Mark Nicolls, MD
Co-Investigator: Ronald G. Gill, PhD
Source: National Institutes of Health - R21 DK70203
Amount: $250,000/yr
Term: 2004-2006

The Mechanism of CD40 T-Cell Dependent Acute Cardiac Allograft Rejection
Principal Investigator: Biagio A. Pietra, MD
Co-Investigator: Ronald G. Gill, PhD
Source: National Institutes of Health - R01 HL67976
Amount: $225,000/yr
Term: 2001-2006

Coronary Artery Calcification in Type 1 Diabetes
Principal Investigator: Marian J. Rewers, MD, PhD, MPH
Source: National Institutes of Health, National Heart, Lung, and Blood Institute - R01 HL61753
Amount: $437,000/yr
Term: 1999-2008

Determinants of Accelerated CVD in Type 1 Diabetes
Principal Investigator: Marian J. Rewers, MD, PhD, MPH
Source: National Institutes of Health, National Heart, Lung, and Blood Institute - RO1 HL079611
Amount: $1,536,537
Term: 2004-2008

Diabetes Autoimmunity Study in the Young (DAISY)
Principal Investigator: Marion J. Rewers, MD, PhD, MPH
Source: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases - RO1 DK32493
Amount: $3,111,271
Term: 1993-2006

Environmental Causes of Type 1 Diabetes (TEDDY)
Principal Investigator: Marian J. Rewers, MD, PhD, MPH
Source: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases - U01 DK63821
Amount: $3,253,203
Term: 2002-2007

Genetic and Environmental Causes of Celiac Disease
Principal Investigator: Marian J. Rewers, MD, PhD, MPH
Source: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases - R01 DK50979
Amount: $1,610,342
Term: 1995-2006

Natural History of Pre-Diabetic Autoimmunity
Principal Investigator: Marian J. Rewers, MD, PhD, MPH
Source: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, National Institute of Allergy and Infectious Diseases - R01 DK32493
Amount: $4,052,324
Term: 1997-2006

Modifier Genes in Autosomal Dominant Polycystic Kidney Disease
Principal Investigator: Robert Schrier, MD
Co-Investigator: Pamela R. Fain, PhD
Source: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases - PO1 DK034039, Project 2
Amount: $150,000/yr
Term: 2001-2006

Microalbuminuria in Diabetes in Children
Principal Investigator: Robert H. Slover II, MD
Source: Boehringer Ingelheim Pharmaceuticals
Amount: $67,500
Term: 2005-2006

Mapping of Vitiligo Susceptibility Genes
Principal Investigator: Richard Spritz, MD
Co-Investigator: Pamela R. Fain, PhD
Source: National Institutes of Health - 5 R01 AROH5584-06
Amount: $547,668
Term: 2004-2009

Diabetes Prevention Trial-1 (Clinical Center Subcontract)
Principal Investigator: H. Peter Chase, MD
Source: National Institutes of Health, Juvenile Diabetes Foundation, American Diabetes Association - 5 U01 DK60782
Amount: $377,395/yr
Term: 2001-2008

Glucose Sensors in Children with Type 1 Diabetes
Principal Investigator: H. Peter Chase, MD
Source: National Institutes of Health - 1 U10 HD041919
Amount: $352,000/yr
Term: 2001-2006

Autoimmunity Prevention Center
Principal Investigator: George S. Eisenbarth, MD, PhD
Source: National Institutes of Health, National Institute of Allergy and Infectious Diseases
Amount: $5,012,089
Term: 2001-2005

Type 1 Diabetes TrialNet, HLA (Autoantibody Laboratory Subcontract)
Principal Investigator: George S. Eisenbarth, MD, PhD
Source: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases - U01-DK61055-01
Amount: $363,820
Term: 2002-2008

Antibodies to Recombinant Autoantigens: Prediction/Immunogenetics
Principal Investigator: George S. Eisenbarth, MD, PhD
Source: National Institutes of Health, National Institute of Allergy and Infectious Diseases - 2 R01 AI39213-06
Amount: $202,500
Term: 2001-2005

In Vivo NOD Evaluation of a "Pathogenic" Insulin Peptide
Principal Investigator: George S. Eisenbarth, MD, PhD
Co-Investigator: Dale Wegmann, PhD
Source: National Institutes of Health, National Institute of Allergy and Infectious Diseases - 2 R01 DK55969
Amount: $189,241/yr
Term: 1998-2006

Multiple Autoantigens/Multiple Epitopes of Pre-Type I Diabetes Mellitus
Principal Investigator: George S. Eisenbarth, MD, PhD
Source: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases - 2 R01 DK32083-20A2
Amount: $166,250/yr
Term: 2001-2005

Core Autoantibody Determination Laboratory for Immune Tolerance Network
Principal Investigator: George S. Eisenbarth, MD, PhD
Source: National Institutes of Health, National Institute of Allergy and Infectious Diseases - N01-AI-95380
Amount: $151,000/yr
Term: 1999-2006

Modeling and Detecting Pathogens of Islet Autoimmunity
Principal Investigator: George S. Eisenbarth, MD, PhD
Source: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases - 1 R01 DK62718
Amount: $100,000/yr
Term: 2002-2006

Mentor-Based Fellowship
Principal Investigator: George S. Eisenbarth, MD, PhD
Source: American Diabetes Association
Amount: $45,000/yr
Term: 1998-2005

Type 1 Genetics Consortium (Subcontract)
Principal Investigator: Rosanna V. Fiallo-Scharer, MD
Source: Benaroya Research Institute at Virginia Mason
Amount: $183,669
Term: 2003-2006

Denver Autoimmunity Center of Excellence
Principal Investigator: Brian Kotzin, MD
Co-Investigators: Pamela R. Fain, PhD, and Ronald G. Gill, PhD
Source: National Institutes of Health, National Institute of Allergy and Infectious Diseases - U19AI46374
Amount: $588,707/yr
Term: 1999-2008

Islet Cell Resource Facility at UCD
Principal Investigator: Ronald G. Gill, PhD
Co-Investigator: John C. Hutton, PhD
Source: National Institutes of Health - 1 U42 RR16599
Amount: $492,558/yr
Term: 2001-2006

Reversal of Diabetes by Islet Transplantation
Principal Investigator: Ronald G. Gill, PhD
Source: National Institutes of Health - R01 DK 33470
Amount: $184,000/yr
Term: 1998-2007

T-Cell-Mediated Injury to Islet Allografts
Principal Investigator: Ronald G. Gill, PhD
Source: National Institutes of Health - R01 DK/AI55333
Amount: $175,000/yr
Term: 1998-2006

Use of Hematopoietic Stem Cells for the Regulation of Autoimmune Diabetes
Principal Investigator: Ronald G. Gill, PhD
Source: National Institutes of Health - R21 AI60349
Amount: $150,000/yr
Term: 2003-2005

Immunobiology of Pancreatic Islet Xenografting
Principal Investigator: Ronald G. Gill, PhD
Source: National Institutes of Health - R01 DK45773
Amount: $132,000/yr
Term: 1998-2006

Pre-Clinical Approaches to Islet Allograft Tolerance
Principal Investigator: Ronald G. Gill, PhD
Source: Juvenile Diabetes Foundation International
Amount: $123,847/yr
Term: 2002-2005

Defining Diabetes in Youth - Ethnic Diversity in Three Populations
Principal Investigator: Richard F. Hamman, MD, DrPH
Source: National Institutes of Health - 5R01 DK059184-03
Amount: $728,517
Term: 2004-2005

Western Registry Grant (SEARCH)
Principal Investigator: Richard F. Hamman, MD, DrPH
Source: Centers for Disease Control and Prevention - U48 CCU815787-04
Amount: $714,085
Term: 2000-2005

Autoreactive T-Cells in the NOD Mouse
Principal Investigator: Kathryn Haskins, PhD
Source: National Institutes of Health - R01 DK50561
Amount: $206,022/yr
Term: 1996-2004

Regulatory T-Cells in the NOD Mouse
Principal Investigator: Kathryn Haskins, PhD
Source: Juvenile Diabetes Foundation International -1-2004-49
Amount: $152,020/yr
Term: 2004-2007

Role of CD40 in the Regulation of Autoreactive T-Cells
Principal Investigator: Kathryn Haskins, PhD
Source: Juvenile Diabetes Foundation International - 1-2004-113
Amount: $152,020/yr
Term: 2004-2007

Tolerogenic APC for the Treatment of Type 1 Diabetes
Principal Investigator: Kathryn Haskins, PhD
Source: American Diabetes Association
Amount: $86,954/yr
Term: 2001-2004

Oxidative Stress in Beta Cell Destruction and Regeneration
Principal Investigator: Kathryn Haskins, PhD
Source: Juvenile Diabetes Foundation International - 5-2004-112
Amount: $45,000/yr
Term: 2004-2005

Diabetes and Endocrinology Research Center
Principal Investigator: John C. Hutton, PhD
Co-Investigators: Ronald G. Gill, PhD, Dale Wegmann, PhD, and Lori Sussel, PhD
Source: National Institutes of Health - P30 DK57516
Amount: $1,036,820/yr
Term: 2000-2005

  • Administrative Core
    Program Director: John C. Hutton, PhD
    Deputy Director: George S. Eisenbarth, MD, PhD
    Amount: $120,023/yr
    Term: 2000-2005
  • Animal Core
    Core Director: Ronald G. Gill, PhD
    Amount: $97,726/yr
    Term: 2000-2005
  • Islet Core
    Core Director: Dale Wegmann, PhD
    Amount: $40,952/yr
    Term: 2000-2005
  • Molecular Core
    Core Director: John C. Hutton, PhD
    Deputy Director: Lori Sussel, PhD
    Amount: $99,674/yr
    Term: 2000-2005
  • Cytometry Core
    Core Director: Jan Jensen, PhD
    Amount: $77,201/yr
    Term: 2000-2005
  • Pilot and Feasibility Project
    Principal Investigator: Dirk Homann, MD, PhD
    Amount: $45,000/yr
    Term: 2004-2005
  • Pilot and Feasibility Project
    Principal Investigator: Joe McCord, PhD
    Amount: $45,000/yr
    Term: 2004-2005
  • Pilot and Feasibility Project
    Principal Investigator: Alexander C. Wiseman, MD
    Amount: $30,000/yr
    Term: 2004-2005
  • Pilot and Feasibility Project
    Principal Investigator: Gongyi Zhang, PhD
    Amount: $30,000/yr
    Term: 2004-2005
  • Pilot and Feasibility Project: Characterization of Pancreatic Pathology in Islet Auto Antibodies Positive Organ Donors
    Principal Investigator: Roberto Gianani, MD
    Co-Investigator: John C. Hutton, PhD
    Amount: $200,000/yr
    Term: 2004-2005

Development and Regeneration of the Endocrine Pancreas (Beta Cell Biology Consortium Program Grant)
Principal Investigator: John C. Hutton, PhD
Co-Investigators: Lori Sussel, PhD, and Jan Jensen, PhD
Source: National Institutes of Health - U19 DK61248
Amount: $957,037/yr
Term: 2001-2005

RIP-Phogrin/EGFP Transgenic Mouse: A Tool for Studying Pancreatic Beta Cell Embryogenesis and Function
Principal Investigator: John C. Hutton, PhD
Source: Juvenile Diabetes Foundation - 1-2001-604
Amount: $187,390/yr
Term: 2001-2004

Islet G6Pase-Related Protein: A Novel -cell Specific Target for T-Cell Mediated Autoimmunity in Type 1 Diabetes
Principal Investigator: John C. Hutton, PhD
Co-Investigator: Howard Davidson, PhD
Source: American Diabetes Association
Amount: $86,957/yr
Term: 2004-2006

Regulation of Insulin Secretion by Protein Phosphorylation
Principal Investigator: John C. Hutton, PhD
Source: National Institutes of Health - R01 DK55597
Amount: $191,609/yr
Term: 1999-2004

Mentor-Based Postdoctoral Fellowship Program
Principal Investigator: John C. Hutton, PhD
Source: American Diabetes Association
Amount: $45,000/yr
Term: 2004-2008

Proteomics Analysis of T-Cell Autoantigens in T1D2
Principal Investigator: Kathryn Haskins, PhD
Co-Investigators: John C. Hutton, PhD, and Howard Davidson, PhD
Source: National Institutes of Health - R21 AI065355
Amount: $308,000/yr
Term: 2004-2006

Morphogenetic Control of -cell Specification
Principal Investigator: Jan Jensen, PhD
Source: American Diabetes Association
Amount: $143,432/yr
Term: 2001-2006

Diabetes Research for Pediatric Endocrinologists (K12) and Fellows Training Grant (T32) [Combined Grant]
Principal Investigator: Georgeanna J. Klingensmith, MD
Source: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases - 5 K12 DK063722-03 and 5 T32 DK063687-03
Amount: $288,963/yr (K12)
$174,996/yr (T32)
Term: 2002-2007

Pediatric Endocrinology Training Position: Exploration of Gene-Environment Interaction
Principal Investigator: Georgeanna J. Klingensmith, MD
Source: Juvenile Diabetes Research Foundation - 13-2002-444
Amount: $50,000/yr
Term: 2002-2005

Psychological Implications of Newborn and Early Childhood Screening for the Increased Risk of Type 1 Diabetes
Principal Investigator: Georgeanna J. Klingensmith, MD
Source: The Talofa Foundation
Amount: $35,000
Term: 2001-2006

A 24-Week Randomized, Double-Blind, Active Controlled, Multicenter Study to Evaluate the Safety and Efficacy of Rosiglitazone when Administered to Pediatric Patients with Type 2 Diabetes Mellitus
Principal Investigator: Georgeanna J. Klingensmith, MD
Source: GlaxoSmithKline
Amount: $11,943/yr
Term: 2001-2004

IRAS Family Study
Principal Investigator: Jill M. Norris, PhD
Source: National Institutes of Health, National Heart, Lung, and Blood Institute - R01 HL61019
Amount: $694,050
Term: 1999-2004

Nutritional Etiology of Pre-Diabetic Autoimmunity
Principal Investigator: Jill M. Norris, PhD
Source: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases - RO1
Amount: $830,000
Term: 1997-2005

Mechanism of CD40 T-Cell Dependent Acute Cardiac Allograft Rejection
Principal Investigator: Biagio A. Pietra, MD
Co-Investigator: Ronald G. Gill, PhD
Source: National Institutes of Health - R01 HL67976
Amount: $225,000/yr
Term: 2001-2005

Natural History of Pre-Diabetic Autoimmunity
Principal Investigator: Marian J. Rewers, MD, PhD, MPH
Source: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, National Institute of Allergy and Infectious Diseases - R01 DK32493
Amount: $ 4,052,324
Term: 1997-2006

Environmental Causes of Type 1 Diabetes (TEDDY)
Principal Investigator: Marian J. Rewers, MD, PhD, MPH
Source: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases - U01 DK63821
Amount: $3,253,203
Term: 2002-2007

Diabetes Autoimmunity Study in the Young (DAISY)
Principal Investigator: Marian J. Rewers, MD, PhD, MPH
Source: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases - RO1 DK32493
Amount: $3,111,271
Term: 1993-2006

Subclinical Heart Disease in Insulin-Dependent Diabetes; Coronary Artery Calcification in Type 1 Diabetes
Principal Investigator: Marian J. Rewers, MD, PhD, MPH
Source: National Institutes of Health, National Heart, Lung, and Blood Institute - R01 HL61753
Amount: $1,985,608
Term: 1999-2008

Genetic and Environmental Causes of Celiac Disease
Principal Investigator: Marian J. Rewers, MD, PhD, MPH
Source: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases - R01 DK50979
Amount: $1,610,342
Term: 1995-2006

Determinants of Accelerated CVD in Type 1 Diabetes
Principal Investigator: Marian J. Rewers, MD, PhD, MPH
Source: National Institutes of Health, National Heart, Lung, and Blood Institute - RO1 HL079611
Amount: $1,536,537
Term: 2004-2008

Molecular Dissection of Immunoregulatory Function
Principal Investigator: Robert Scheinman, PhD
Co-Investigator: Dale Wegmann, PhD
Source: National Institutes of Health - R21 DK062820
Amount: $100,000/yr
Term: 2003-2005

The Role of Gata4 in Regulating Exocrine Pancreas Development
Principal Investigator: Lori Sussel, PhD
Source: National Institutes of Health - R01DK641461
Amount: $176,000/yr
Term: 2003-2008

Core Center Grant/Transgenic Mouse Core
Principal Investigator: Diego Restrepo, PhD
Co-Investigator: Lori Sussel, PhD
Source: National Institutes of Health - P30 DC004657-01
Amount: $134,634/yr
Term: 2000-2005

Transcriptional Regulation of Exocrine Pancreas Differentiation
Principal Investigator: Lori Sussel, PhD
Source: National Institutes of Health - R21DK061151
Amount: $100,000/yr
Term: 2001-2003

American Diabetes Association Career Development Award: The Role of Nkx2.2 in the Development of the Pancreatic Beta Cell
Principal Investigator: Lori Sussel, PhD
Source: American Diabetes Association
Amount: $87,000/yr
Term: 2000-2003

Adenoviral Vector Manipulation of T-Cell Pathogenesis in NOD Mice
Principal Investigator: Dale Wegmann, PhD
Source: American Diabetes Association
Amount: $100,000/yr
Term: 2001-2004

Exploring Diabetes and Depression in Youth
Principal Investigator: Philippe Weintraub, MD
Source: National Institutes of Health - RO1MH068126
Amount: $6,976/yr
Term: 2002-2005

Treatment Alternatives in Pediatric Type 2 Diabetes and Population-Based Prevention Strategies (TODAY)
Principal Investigator: Philip S. Zeitler, MD, PhD
Co-Investigator: Georgeanna T. Klingensmith, MD
Source: National Institutes of Health - 1 U01DK061242-03
Amount: $469,139
Term: 2001-2008

Head CT in the Evaluation of 1st Afebrile Seizures
Principal Investigator: Lalit Bajaj, MD, MPH
Co-Investigators: Mark G. Roback, MD, Louis C. Hampers, MD, MBA, Carol Okada, MD, and Rebecca Fastle, MD
Term: 2000-2004

Postreduction Management of Intussusception
Principal Investigator: Lalit Bajaj, MD, MPH
Co-Investigators: Mark G. Roback, MD, and Shayne Bland, MSc
Term: 2000-2002

Emergency Medical Services for Children Partnership Grant
Principal Investigator: F. Keith Battan, MD
Source: US Department of Health and Human Services, Maternal and Child Health Bureau -
FLAEMS01-00250
Amount: $122,000
Term: 2000-2001

L.O.C.O. (Latinos Overcoming Cultural Obstacles) "Needs Assessment for The Children's Hospital"
Principal Investigator: Sonja Burbano-O'Leary, MD
Co-Investigator: Louis C. Hampers, MD, MBA
Source: Colorado Chapter of the American Academy of Pediatrics
Amount: $3,000
Term: 2001

The Truth about Language Barriers
Principal Investigator: Sonja Burbano-O'Leary, MD
Co-Investigators: Louis C. Hampers, MD, MBA, and Stephen Federico, MD
Source: Colorado Chapter of the American Academy of Pediatrics
Amount: $3,000
Term: 2001-ongoing

Jungle Mobile: A Mobile Injury Prevention Project for Children
Principal Investigator: Kathryn D. Emery, MD
Co-Investigators: Allison Hawkes, MD, MS, Theresa Rapstine, RN, and Victoria Cassenbaugh, RN
Term: 1998-ongoing

A Screening Tool for the Detection of Child Abuse in the Emergency Department Setting
Joint Project with the Child Advocacy Protection Team

Principal Investigator: Kathryn D. Emery, MD
Term: 2001

Seat Belt and Car Safety Seat Use in SUVs
Primary Investigator: Kathryn D. Emery, MD
Co-Investigators: Lisa Hardin Van Bramer, MD, and Kevin Raines, MD
Source: National Highway Traffic Safety Administration - STNH22-01-H-05-257
Amount: $350,000
Term: 2001-2003

Childhood Injury Prevention Concerns of Migrant and Seasonal Farm Workers in Weld County
Principle Investigator: Kathryn D. Emery, MD
Co-Investigator: S. Glenn Faries, MD
Source: Colorado Injury Control Research Center
Amount: $15,000
Term: 2002-2003

Domestic Violence Policies in Pediatric Emergency Departments
Principle Investigator: Kathryn D. Emery, MD
Co-Investigators: Sheila Sullivan, MD, Andrew P. Sirotnak, MD, and Stephanie Stronks-Knapp, MD
Term: 2002-ongoing

Development of an Injury-Free Coalition for Kids
Principal Investigator: S. Glenn Faries, MD
Co-Investigator: Kathryn D. Emery, MD
Term: 2001-ongoing

Resident Education in the Emergency Department
Principal Investigator: S. Glenn Faries, MD
Term: 2002-ongoing

Need for Atropine for Emergent Pediatric Intubations
Principal Investigator: Rebecca Fastle, MD
Co-Investigator: Mark G. Roback, MD
Term: 1999-ongoing

Resuscitation Teaching at Primary Care Centers
Principal Investigator: Margaret Ferguson, MD
Co-Investigator: Mark G. Roback, MD
Term: 1998-ongoing

Utility of Anaerobic Blood Cultures in a Pediatric Emergency Department
Principal Investigator: Stephen Freedman, MD
Co-Investigator: Genie E. Roosevelt, MD, MPH
Term: 2001-2003

PEM Collaborative Research Committee, Cerebral Edema and DKA
Principal Investigator: Nicole Glaser, MD
Co-Investigator: Mark G. Roback, MD
Term: 1998-2001

Comparison of Oral Prednisone vs. Dexamethasone in Pediatric Asthma
Principal Investigator: Richard A. Greenberg, MD
Co-Investigators: Genie E. Roosevelt, MD, MPH, and Gwendolyn S. Kerby, MD
Term: 2002-ongoing

Peak Flow vs. Spirometry in Acute Asthma
Principal Investigator: David Gutglass, MD
Co-Investigator: Louis C. Hampers, MD, MBA
Term: 1997-ongoing

A.C.C.E.S.S. for Latinos: After-Hours Call Center and Extended Spanish Service
Principal Investigator: Louis C. Hampers, MD, MBA
Co-Investigators: Lauren Clark, PhD, RN, and Stephen Berman, MD
Term: 2001-2002

The Impact of Interpreters on Resource Utilization in a Pediatric Emergency Department
Principal Investigator: Louis C. Hampers, MD, MBA
Co-Investigator: Jennifer McNulty, MD
Term: 1999-2002

Physician-Based Practice Pattern Variations in the Management of AGE
Principal Investigator: Louis C. Hampers, MD, MBA
Co-Investigator: Elizabeth Powell, MD, MPH
Term: 2001-ongoing

Practice Variation in the Management of Croup
Principal Investigator: Louis C. Hampers, MD, MBA
Co-Investigators: S. Glenn Faries, MD, and Steven R. Poole, MD
Term: 1999-2002

Regional After-Hours Urgent Care Provided by a Tertiary Children's Hospital
Principal Investigator: Louis C. Hampers, MD, MBA
Co-Investigators: S. Glenn Faries, MD, and Steven R. Poole, MD
Term: 2001-2002

Booster Seat Project
Principal Investigator: Lisa Hardin Van Bramer, MD
Co-Investigator: Kathryn D. Emery, MD
Source: Emergency Medical Services and Kiwanis Pediatric Trauma Institute
Amount: $18,000
Term: 2001-2002

Association of Influenza with Bacterial Tracheitis
Principal Investigator: Ron L. Kaplan, MD
Co-Investigators: Mark G. Roback, MD, and Peggy Kelly, MD
Term: 2002-ongoing

Safety, Tolerability and Efficacy Study of Levalbuterol and Racemic Albuterol in Pediatric Patients Birth to 48 Months Old with Reactive Airways Disease in an Acute Setting
Principal Investigator: Gwendolyn S. Kerby, MD
Co-Investigator: S. Glenn Faries, MD
Term: 2001-2002

Effect of Ondansetron on Ketamine Sedation-Associated Vomiting
Principal Investigator: William T. Langston, MD
Co-Investigators: Joseph E. Wathen, MD, and Mark G. Roback, MD
Source: The Children's Hospital Research Institute
Amount: $5,000
Term: 2002-ongoing

Effect of Medical Spanish Classes on Satisfaction of Hispanic Patients in Pediatric Emergency Department
Principal Investigator: Suzanne Mazor, MD
Co-Investigators: Vidya Chande, MD, Louis C. Hampers, MD, MBA, and Steven Krug, MD
Term: 2000-2002

Interpretation of Traumatic Lumbar Punctures: Who Can Go Home?
Principal Investigator: Suzan Mazor, MD
Co-Investigators: Jennifer McNulty, MD, and Genie E. Roosevelt, MD, MPH
Term: 2001-ongoing

How Is Emergency Department Decision-Making Affected by the Existence of Reliable Follow-Up?
Principal Investigator: Jennifer McNulty, MD
Co-Investigators: Louis C. Hampers, MD, MBA, and Steven Krug, MD
Term: 1999-2001

Decision Rules for Obtaining Radiographs in Pediatric Knee Injuries
Principal Investigator: Brian Moore, MD
Co-Investigators: Louis C. Hampers, MD, MBA, and Kathryn Emery, MD
Term: 1998-ongoing

Indications for Knee Radiographs in Pediatric Patients with Acute Knee Injuries/Validation of a Clinical Decision Rule
Principal Investigator: Brian Moore, MD
Co-Investigators: Carol Turner, MD, and Kathryn D. Emery, MD
Term: 2000-ongoing

Correlation of Hemolysis with Facticous Hyperkalemia
Principal Investigator: Heather Owens, MD
Co-Investigator: Louis C. Hampers, MD, MBA
Term: 2002-ongoing

Acute Complication of Type 1 Diabetes in Children
Primary Investigator: Arleta B. Rewers, MD, PhD
Co-Investigators: Mark G. Roback, MD, and Joan P. Bothner, MD
Term: 2001-ongoing

Childhood Pedestrian Injuries
Primary Investigator: Arleta B. Rewers, MD, PhD
Term: 2002-ongoing

Femur Fractures and Associated Injuries
Principal Investigator: Arleta B. Rewers, MD, PhD
Co-Investigators: Kathryn D. Emery, MD, and F. Keith Battan, MD
Term: 2000-ongoing

Are Chest X-Rays Required for all First-Time Wheezers?
Principal Investigator: Mark G. Roback, MD
Co-Investigators: Mark E. Anderson, MD, and John D. Strain, MD
Term: 1998-ongoing

Comparison of the Efficacy and Safety of Sedation Drugs Used in a Pediatric Emergency Department
Principal Investigator: Mark G. Roback, MD
Co-Investigators: Joseph E. Wathen, MD, and Joan P. Bothner, MD
Term: 1999-ongoing

IV vs. IM Ketamine Sedation in the Pediatric Emergency Department
Principal Investigator: Mark G. Roback, MD
Co-Investigator: Joseph E. Wathen, MD
Source: The Children's Hospital Research Institute
Amount: $35,000
Term: 2000-ongoing

Pediatric Resuscitation Practice and Success Rate
Principal Investigator: Mark G. Roback, MD
Co-Investigator: Rebecca Fastle, MD
Term: 2000-ongoing

Predictors of Which Patients will Benefit from Observations vs. Hospital Admission
Principal Investigator: Genie E. Roosevelt, MD, MPH
Co-Investigator: S. Glenn Faries, MD
Term: 2002-ongoing

Randomized, Double-Blind Study of Intravenous Fluids With and Without Dextrose in the Treatment of Dehydration in Pediatric Patients with Vomiting and Ketosis
Principal Investigator: Genie E. Roosevelt, MD, MPH
Term: 2002-ongoing

The Effect of Dehydration on the QT Interval of Healthy Children
Principal Investigator: Carl Shaw, MD
Co-Investigators: Joseph E. Wathen, MD, and Michael S. Schaffer, MD
Term: 2001

The Prevalence of Urinary Tract Infections in Febrile Children with AGE
Principal Investigator: Carl Shaw, MD
Co-Investigator: Louis C. Hampers, MD, MBA
Term: 2002-ongoing

Use of Complementary Medicine in Pediatric Patients with Asthma
Principal Investigator: Alison Siegel Tothy, MD
Co-Investigator: Genie E. Roosevelt, MD, MPH
Term: 2001-2002

Associations between Insurance Type and Pediatric Admission Rate in Colorado, 1993-1999: Is Managed Care Fulfilling Its Promise?
Principal Investigator: Marion R. Sills, MD, MPH
Co-Investigators: Jill Joseph, MD, PhD, and James K. Todd, MD
Term: 2000-ongoing

Associations of Parental Depression and Child Health Outcomes
Principal Investigator: Marion R. Sills, MD, MPH
Co-Investigators: Allison Kempe, MD, John Steiner, MD, David Price, MD, and David Magid, MD
Term: 2002-ongoing

Comparison of the Longitudinal Marginal Cost, Morbidity and Mortality of Inflicted and Unintentional Head Injuries in Young Children in a Nationwide Sample of Children's Hospitals
Principal Investigator: Marion R. Sills, MD, MPH
Co-Investigator: Anne Libby, PhD
Term: 2001-ongoing

Costs of Childhood Physical Abuse: Comparing Inflicted and Unintentional Head Injuries in Colorado Inpatients Under Three Years Old
Principal Investigator: Marion R. Sills, MD, MPH
Co-Investigator: Anne Libby, PhD
Term: 2001-ongoing

Epidemiology of Pediatric Psychiatric Visits to US Emergency Departments, Based on the National Hospital Ambulatory Medical Care Survey 1995-1999
Principal Investigator: Marion R. Sills, MD, MPH
Co-Investigator: Shayne Bland, MSc
Term: 2001-ongoing

Hospital-Level Predictors of Inefficiency Amongst Hospitalized Patients in New York State
Principal Investigator: Marion R. Sills, MD, MPH
Co-Investigators: Jill Joseph, MD, PhD, and Andrew Racine, MD, PhD
Term: 2000-ongoing

Management of Acute Gastroenteritis Visits to Emergency Departments Based on the National Hospital Ambulatory Medical Care Survey, 1995-1999
Principal Investigator: Marion R. Sills, MD, MPH
Co-Investigator: Shayne Bland, MSc
Term: 2001-ongoing

Management of Bronchiolitis Visits to Emergency Departments Based on the National Hospital Ambulatory Medical Care Survey, 1993-1999
Principal Investigator: Marion R. Sills, MD, MPH
Co-Investigator: Shayne Bland, MSc
Term: 2001-ongoing

Comparison of Fascia Iliaca Compartment Nerve Block to Traditional Systemic Analgesics for Femur Fractures in a Pediatric Emergency Department
Principal Investigator: Joseph E. Wathen, MD
Co-Investigators: Glen Merritt, MD, Gaia Georgopoulos, MD, and F. Keith Battan, MD
Source: The Children's Hospital Research Institute
Amount: $17,594
Term: 2001-2004

Pediatric EKG Interpretation Accuracy by Pediatric Emergency Medicine Physicians
Principal Investigator: Joseph E. Wathen, MD
Co-Investigators: Arleta Rewers, MD, PhD, Angela Yetman MD, and Michael Schaffer MD
Term: 2001-ongoing

A Randomized Trial of Telephonic vs. On-Site Language Interpretation in a Pediatric ED
Principal Investigator: Ethan S. Wiener, MD
Co-Investigator: Louis C. Hampers, MD, MBA
Term: 2002-ongoing