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Allergy, Immunology and Rheumatology - Research


The faculty at National Jewish Health (NJH) and Children's Hospital Colorado have numerous research interests with major programs in the regulation of allergic responses, asthma, inflammation, autoimmunity, inflammatory cell function, signal transduction, apoptosis, and compliance issues. In addition, the entire rheumatology division is involved with multicenter research studies through the Childhood Arthritis and Rheumatology Research Alliance, including ARCHIVE (A Registry for Children with Vasculitis: e-entry), a project towards establishing a computerized database of children with vasculitis and EDSS (Enhanced Drug Safety Surveillance), a study designed to capture all serious adverse events and important medical events in patients with Juvenile Idiopathic Arthritis.


Faculty Research Interests


Dr. Leonard Dragone’s research lab focuses on understanding how alterations in lymphocyte signaling pathways underlie the development of autoimmune diseases such as juvenile idiopathic arthritis, rheumatoid arthritis, and Systemic Lupus Erythematosus.

Dr. Erwin Gelfand runs a research laboratory at NJH that focuses on understanding the pathophysiology and treatment of allergy, asthma, and immunodeficiency.  He is involved in multicenter research through NIH-funded consortiums. 

Dr. J. Roger Hollister's research in rheumatology focuses on innovative treatment for Wegener's Granulomatosis.

Dr. Jennifer Soep has been conducting research on atherosclerosis in Systemic Lupus Erythematosus (SLE) and is participating in a joint project between Children's Colorado and the University of Colorado School of Medicine Division of Adult Rheumatology to investigate the role of complement receptor 2 and the development and manifestations of SLE.

Visit the National Jewish Health Research page for additional faculty research interests.