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Edwin Liu, MD

Associate Professor of Pediatrics


   Phone: 720-777-1234 (TBD)
   E-mail: (TBD)

Section of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics
Barbara Davis Center for Childhood Diabetes
Children's Hospital Colorado

Pediatrics, Pediatric Gastroenterology

Edwin Liu, MD, earned his medical degree from Boston University School of Medicine in 1996. He completed his Pediatric Residency at St. Christopher’s Hospital for Children in Philadelphia, Pennsylvania, in 1999, and a Fellowship in Pediatric Gastroenterology at the University of Colorado School of Medicine in 2003. Dr. Liu joined the faculty of the Department of Pediatrics at the University of Colorado School of Medicine and Children’s Hospital Colorado in 2003.

Dr. Liu’s research work focuses on the study of autoimmunity in type 1 diabetes and celiac diseas, eanalysis of current diagnostic testing for celiac disease, and the genetics of celiac disease. He has been awarded a five-year grant from the National Institutes of Health to research “Altering the Pl of Peptide Vaccines to Avoid Anaphylaxis,” and he holds a patent for “Antibodies to Insulin Peptide B:9-23 Prevent Type 1 Diabetes.”

Dr. Liu has won several prestigious awards. He serves as a peer reviewer for several professional medical journals and is widely published in both journal articles and book chapters.

  • Young Clinical Investigator's Award, NASPGHAN, 2010
  • Associate Editor, Journal of Pediatric Gastroenterology and Nutrition, 2003-2006

Publications in PubMed (partial list)

  • Lu BR, Gralla J, Liu E, Dobyns EL, Narkewicz MR, Sokol RJ. Evaluation of a scoring system for assessing prognosis in pediatric acute liver failure. Clin Gastroenterol Hepatol. 2008 Oct;6(10):1140-5. [PMID: 18928939]
  • Kobayashi M, Jasinski J, Liu E, Li M, Miao D, Zhang L, Yu L, Nakayama M, Eisenbarth GS. Conserved T cell receptor alpha-chain induces insulin autoantibodies. Proc Natl Acad Sci USA. 2008 Jul;105(29):10090-4. [PMID: 18626021]
  • Barker JM, Liu E. Celiac disease: pathophysiology, clinical manifestations, and associated autoimmune conditions. Adv Pediatr. 2008;55(1):349-65. [PMID: 19048738]
  • Liu E, Eisenbarth GS. Accepting clocks that tell time poorly: fluid-phase versus standard ELISA autoantibody assays. Clin Immunol. 2007 Nov;125(2):120-6. [PMID: 17904423]
  • Liu E, Li M, Emery L, Taki I, Barriga K, Tiberti C, Eisenbarth GS, Rewers MJ, Hoffenberg EJ. Natural history of antibodies to deamidated gliadin peptides and transglutaminase in early childhood celiac disease. J Pediatr Gastroenterol Nutr. 2007 Sep;45(3):293-300. [PMID: 17873740]
  • Kobayashi M, Abiru N, Arakawa T, Fukushima K, Zhou H, Kawasaki E, Yamasaki H, Liu E, Miao D, Wong FS, Eisenbarth GS, Eguchi K. Altered B:9 23 insulin, when administered intranasally with cholera toxin adjuvant, suppresses the expression of insulin autoantibodies and prevents diabetes. J Immunol. 2007 Aug;179(4):2082-8. [PMID: 17675466]
  • Nakayama M, Beilke JN, Jasinski JM, Kobayashi M, Miao D, Li M, Coulombe MG, Liu E, Elliott JF, Gill RG, Eisenbarth GS. Priming and effector dependence on insulin B:9-23 peptide in NOD islet autoimmunity. J Clin Invest. 2007 Jul;117(7):1835-43. [PMID: 17607359]
  • Simmons JH, Klingensmith GJ, McFann K, Rewers M, Taylor J, Emery LM, Taki I, Vanyi S, Liu E, Hoffenberg EJ. Impact of celiac autoimmunity on children with type 1 diabetes. J Pediatr. 2007 May;150(5):461-6. [PMID: 17452216]
  • Hoffenberg EJ, Liu E. Celiac disease for the allergist: who and how to screen. Allergy Asthma Proc. 2007 Jan-Feb;28(1):20-4. [PMID: 17390752]
  • Liu E, Li M, Jasinski J, Kobayashi M, Gianani R, Nakayama M, Eisenbarth GS. Deleting islet autoimmunity. Cell Biochem Biophys. 2007;48(2-3):177-82. [PMID: 17709887]
  • Nakayama M, Babaya N, Miao D, Gianani R, Liu E, Elliott JF, Eisenbarth GS. Long-term prevention of diabetes and marked suppression of insulin autoantibodies and insulitis in mice lacking native insulin B9-23 sequence. Ann N Y Acad Sci. 2006 Oct;1079:122-9. [PMID: 17130542]
  • Jasinski JM, Yu L, Nakayama M, Li MM, Lipes MA, Eisenbarth GS, Liu E. Transgenic insulin (B:9-23) T-cell receptor mice develop autoimmune diabetes dependent upon RAG genotype, H-2g7 homozygosity, and insulin 2 gene knockout. Diabetes. 2006 Jul;55(7):1978-84. [PMID: 16804066]
  • Liu E, MacKenzie T, Dobyns EL, Parikh CR, Karrer FM, Narkewicz MR, Sokol RJ. Characterization of acute liver failure and development of a continuous risk of death staging system in children. J Hepatol. 2006 Jan;44(1):134-41. [PMID: 16169116]
  • Devendra D, Jasinski J, Melanitou E, Nakayama M, Li M, Hensley B, Paronen J, Moriyama H, Miao D, Eisenbarth GS, Liu E. Interferon-alpha as a mediator of polyinosinic:polycytidylic acid-induced type 1 diabetes. Diabetes. 2005 Sep;54(9):2549-56. [PMID: 16123342]
  • Nakayama M, Abiru N, Moriyama H, Babaya N, Liu E, Miao D, Yu L, Wegmann DR, Hutton JC, Elliott JF, Eisenbarth GS. Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice. Nature. 2005 May 12;435(7039):220-3. [PMID: 15889095]
  • Liu E, Li M, Bao F, Miao D, Rewers MJ, Eisenbarth GS, Hoffenberg EJ. Need for quantitative assessment of transglutaminase autoantibodies for celiac disease in screening-identified children. J Pediatr. 2005 Apr;146(4):494-9. [PMID: 15812452]
  • Liu E, Rewers M, Eisenbarth GS. Genetic testing: who should do the testing and what is the role of genetic testing in the setting of celiac disease? Gastroenterology. 2005 Apr;128(4 Suppl 1):S33-7. [PMID: 15825124]