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D. Dunbar Ivy, MD

Professor of Pediatrics


 

Section Head, Cardiology
Selby's Chair in Pediatric Cardiology
Director, Pulmonary Hypertension Program

Contact
   Phone: 720-777-1234 (TBD)
   E-mail: (TBD)

Affiliations
Section of Cardiology, Department of Pediatrics
Pediatric Heart Lung Center
Children's Hospital Colorado

Certifications
Pediatrics, Pediatric Cardiology

D. Dunbar Ivy, MD, earned his medical degree from Tulane University School of Medicine in 1988. At the University of Colorado School of Medicine he completed his Pediatric Residency in 1991 and his Fellowship in Pediatric Cardiology in 1994. Dr. Ivy joined the faculty of the Department of Pediatrics at the University of Colorado School of Medicine and Children’s Hospital Colorado in 1994. He was appointed Director of the Pulmonary Hypertension Program in 2003 and Section Head of Cardiology in 2003.

Dr. Ivy has received grant support for many research studies and ongoing clinical trials. He is interested in research involving pulmonary hypertension, genomics, and proteomics of pulmonary vascular disease.

Dr. Ivy is the recipient of numerous awards and honors. He is a member of numerous professional societies and institutional committees. Dr. Ivy served on the Editorial Board for Advances in Pulmonary Hypertension. He has published hundreds of articles, book chapters, abstracts, and scholarly reviews, and he is a sought-after speaker worldwide.

  • Member, Scientific Leadership Council, Pulmonary Hypertension Association, 2005-present
  • 5280 Magazine’s Top Doctors in Denver, 2005-present
  • Pediatric Faculty Research Mentor, Shunichi Takatsuki, MD, 2010-2012
  • Board of Trustees, Pulmonary Hypertension Association, 2011
  • Editorial Board, Advances in Pulmonary Hypertension, Pulmonary Hypertension Association, 2011
  • Fern Primack “Heart Who Cares” Award, Little Hearts Luncheon Committee/ TCH Foundation, 2008
  • Selby's Chair in Pediatric Cardiology, 2003-2006

Publications in PubMed

  • Phelps CM, Mengshol S, Ivy DD. A curious isolated cystic lesion of the membranous atrioventricular septum. Cardiol Young. 2008 Dec;18(6):631-4. [PMID: 18950547]
  • Malhotra SP, Lacour-Gayet F, Campbell DN, Miyamoto S, Clarke DR, Dines ML, Ivy DD, Mitchell MB. Outcomes of reparative and transplantation strategies for multilevel left heart obstructions with mitral stenosis. Ann Thorac Surg. 2008 Oct;86(4):1305-9. [PMID: 18805182]
  • Malhotra SP, Ivy DD, Mitchell MB, Campbell DN, Dines ML, Miyamoto S, Kay J, Clarke DR, Lacour-Gayet F. Performance of cavopulmonary palliation at elevated altitude: midterm outcomes and risk factors for failure. Circulation. 2008 Sep;118(14 Suppl):S177-81. [PMID: 18824752]
  • Doran AK, Ivy DD, Barst RJ, Hill N, Murali S, Benza RL. Guidelines for the prevention of central venous catheter-related blood stream infections with prostanoid therapy for pulmonary arterial hypertension. Int J Clin Pract Suppl. 2008 Jul;(160):5-9. [PMID: 18638170]
  • Villavicencio K, Ivy D, Cole L, Nuss R. Symptomatic pulmonary hypertension in a child with sickle cell disease. J Pediatr. 2008 Jun;152(6):879-81. [PMID: 18492535]
  • Hunter KS, Gross JK, Lanning CJ, Kirby KS, Dyer KL, Ivy DD, Shandas R. Noninvasive methods for determining pulmonary vascular function in children with pulmonary arterial hypertension: application of a mechanical oscillator model. Congenit Heart Dis. 2008 Mar;3(2):106-16. [PMID: 18380759]
  • Mourani PM, Ivy DD, Rosenberg AA, Fagan TE, Abman SH. Left ventricular diastolic dysfunction in bronchopulmonary dysplasia. J Pediatr. 2008 Feb;152(2):291-3. [PMID: 18206706]
  • Mourani PM, Sontag MK, Younoszai A, Ivy DD, Abman SH. Clinical utility of echocardiography for the diagnosis and management of pulmonary vascular disease in young children with chronic lung disease. Pediatrics. 2008 Feb;121(2):317-25. [PMID: 18245423]
  • Hunter KS, Lee PF, Lanning CJ, Ivy DD, Kirby KS, Claussen LR, Chan KC, Shandas R. Pulmonary vascular input impedance is a combined measure of pulmonary vascular resistance and stiffness and predicts clinical outcomes better than pulmonary vascular resistance alone in pediatric patients with pulmonary hypertension. Am Heart J. 2008 Jan;155(1):166-74. [PMID: 18082509]
  • Ivy DD, Doran AK, Smith KJ, Mallory GB Jr, Beghetti M, Barst RJ, Brady D, Law Y, Parker D, Claussen L, Abman SH. Short- and long-term effects of inhaled iloprost therapy in children with pulmonary arterial hypertension. J Am Coll Cardiol. 2008 Jan 15;51(2):161-9. [PMID: 18191742]
  • Malhotra SP, Ivy DD, Mitchell MB, Campbell DN, Dines M, Miyamoto S, Duster M, Kay J, Lacour-Gayet F. Performance of cavopulmonary palliation at elevated altitude: midterm outcomes and risk factors for failure. American Heart Association 2007 Scientific Sessions, November 3-7; Orlando, FL: 2007.
  • Barst R, Berman-Rosenzweig E, Horn E, Saiman L, Lee L, Southwick K, Kohlerschmidt D, Smith P, Gomberg-Maitland M, Weber S, Ivy D, Doran A, McGoon M, Severson C, Rubenfire M, McLaughlin V, Feldman, J, Tanner C, Chin K, Kingman M. Bloodstream infections among patients treated with intravenous epoprostenol or intravenous treprostinil for pulmonary arterial hypertension - seven sites, United States, 2003-2006. MMWR. 2007;56(8):170-72. [PMID: 17332729]
  • Beghetti M, Doran AK, Mallory G, Barst RJ, Law Y, Abman SH, Ivy DD. Inhaled iloprost therapy in children with pulmonary arterial hypertension. Cardiol Young. 2007;17(1):78.
  • Beghetti M, Haworth SG, Barst RJ, Jais X, Acar P, Fraisse A, Ivy DD, Schulze-Neick I, Bonnet D, Berger RMF. Pharmacokinetics and safety profile of a novel formulation of bosentan in children with pulmonary arterial hypertension (PAH): FUTURE-1 study. Eur Heart J. 2007;28(Suppl 1):150.
  • Buckvold S, Tissot-Daguette C, Phelps CM, Mitchell MB, Campbell DN, Ivy DD, Pietra BA, Miyamoto SD. Primary heart transplantation for hypoplastic left heart syndrome: effect of waiting time on pulmonary artery pressure. Pediatr Crit Care Med. 2007;8(3):A242.
  • Carmosino MJ, Friesen RH, Doran A, Ivy DD. Perioperative complications in children with pulmonary hypertension undergoing non-cardiac surgery or cardiac catheterization. Anes Anal. 2007;104(3):521-7. [PMID: 17312201]
  • Drexler ES, Quinn TP, Slifka AJ, McCowan CN, Bischoff JE, Wright JE, Ivy DD, Shandas R. Comparison of mechanical behavior among the extrapulmonary arteries from rats. J Biomech Eng. 2007;40(4):812-19. [PMID: 16682044]
  • Ivy DD, Doran AK, Claussen LC. Transition of stable pediatric patients with pulmonary arterial hypertension from intravenous epoprostenol to intravenous treprostinil. Am J Cardiol. 2007;99(5):696-8. [PMID: 17317374]
  • Phelps CM, Tissot-Daguette C, Buckvold S, Ivy DD, Pietra BA, Miyamoto SD. Inotropic and mechanical support in acute graft rejection for pediatric heart transplant patients. Pediatr Crit Care Med. 2007;8(3):A282.
  • Tissot-Daguette C, Buckvold S, Phelps CM, Ivy DD, Campbell DN, Mitchell MB, Pietra BA, Miyamoto SD. Use of ECMO to reverse primary graft failure after heart transplantation in children. Pediatr Crit Care Med. 2007;8(3):A279.
  • Yetman AT, Beroukhim RS, Ivy DD, Manchester D. Importance of the clinical recognition of Loeys-Dietz Syndrome in the neonatal period. Pediatrics. 2007;119(5):1199-02. [PMID: 17470566]
  • Zhang Y, Dunn ML, Hunter KS, Lanning C, Ivy DD, Claussen L, Chen J, Shandas R. Application of a microstructural constitutive model of the pulmonary artery to patient-specific studies: validation and effect of orthotropy. J Biomech Eng. 2007;129(2):193-201. [PMID: 17408324]
  • Artrip JH, Campbell DN, Ivy DD, Almodovar MC, Chan KC, Mitchell MB, Clarke DR, Lacour-Gayet F. Birth weight and complexity are significant factors for the management of hypoplastic left heart syndrome. Ann Thorac Surg. 2006 Oct;82(4):1252-7. Discussion 1258-9. [PMID: 16996917]
  • Hunter KS, Lanning CJ, Chen SY, Zhang Y, Garg R, Ivy DD, Shandas R. Simulations of congenital septal defect closure and reactivity testing in patient-specific models of the pediatric pulmonary vasculature: A 3D numerical study with fluid-structure interaction. J Biomech Eng. 2006 Aug;128(4):564-72. [PMID: 16813447]
  • Hunter KS, Zhang Y, Lanning C, Ivy DD, Shandas R. Clinical and numerical studies supporting pulmonary vascular input impedance as a determinant of global vascular stiffness in pediatric pulmonary hypertension. Proceedings of BIO2006; 2006 Jun 21-25; Amelia Island, FL. Summer Bioengineering Conference; 2006.
  • Dyer K, Lanning C, Das B, Lee PF, Ivy DD, Valdes-Cruz L, Shandas R. Noninvasive Doppler tissue measurement of pulmonary artery compliance in children with pulmonary hypertension. J Am Soc Echocardiogr. 2006 Apr;19(4):403-12. [PMID: 16581479]
  • Resnik E, Herron J, Fu R, Ivy DD, Cornfield DN. Oxygen tension modulates the expression of pulmonary vascular BKCa channel alpha- and beta- subunits. Am J Physiol Lung Cell Mol Physiol. 2006 Apr;290(4):L761-L8. [PMID: 16284215]
  • Dyer KL, Pauliks LB, Das B, Shandas R, Ivy D, Shaffer EM, Valdes-Cruz LM. Use of myocardial performance index in pediatric patients with idiopathic pulmonary arterial hypertension. J Am Soc Echocardiogr. 2006 Jan;19(1):21-7. [PMID: 16423665]
  • Ihida-Stansbury K, McKean DM, Gebb SA, Martin JF, Stevens T, Nemenoff R, Vaughn J, Lane K, Loyd J, Wheeler L, Morrell NW, Ivy D, Jones PL. Regulation and functions of the paired-related homeobox gene PRX1 in pulmonary vascular development and disease. Chest. 2005 Dec;128(6 Suppl):591S. [PMID: 16373852]
  • Imamura M, Vitello AM, Limbird JN, Ivy DD, Fallon MB, Carter EP. Endothelin-B receptor overexpression prevents hypoxic pulmonary hypertension in cirrhotic rats. Chest. 2005 Dec;128(6 Suppl):580S-1S. [PMID: 16373843]
  • Resnik E, Herron J, Fu R, Ivy DD, Cornfield DN. Oxygen tension modulates the expression of pulmonary vascular BKCa channel alpha- and beta-subunits. Am J Physiol Lung Cell Mol Physiol. 2006 Apr;290(4):L761-L768. Epub 2005 Nov 11. [PMID: 16284215]
  • Rosenzweig EB, Ivy DD, Widlitz A, Doran A, Claussen LR, Yung D, Abman SH, Morganti A, Nguyen N, Barst RJ. Effects of long-term bosentan in children with pulmonary arterial hypertension. J Am Coll Cardiol. 2005 Aug 16;46(4):697-704. [PMID: 16098438]
  • Zhang Y, Dunn ML, Drexler ES, McCowan CN, Slifka AJ, Ivy DD, Shandas R. A microstructural hyperelastic model of pulmonary arteries under normo- and hypertensive conditions. Ann Biomed Eng. 2005 Aug;33(8):1042-52. [PMID: 16133913]
  • Rashid A, Ivy DD. Pulmonary hypertension in children. Curr Paediatr. 2006;16: 237-47.
  • Condino AA, Ivy DD, O'Connor JA, Narkewicz MR, Mengshol S, Whitworth JR, Claussen L, Doran A, Sokol RJ. Portopulmonary hypertension in pediatric patients. J Pediatr. 2005 Jul;147(1):20-6. [PMID: 16027687]
  • Ivy DD, McMurtry IF, Colvin K, Imamura M, Oka M, Lee DS, Gebb S, Jones PL. Development of occlusive neointimal lesions in distal pulmonary arteries of endothelin B receptor-deficient rats: a new model of severe pulmonary arterial hypertension. Circulation. 2005 Jun 7;111(22):2988-96. [PMID: 15927975]
  • Das BB, Narkewicz MR, Sokol RJ, Chen YT, Bali D, Li SC, Matthews MR, Mierau GW, Ivy DD. Amylopectinosis disease isolated to the heart with normal glycogen branching enzyme activity and gene sequence. Pediatr Transplant. 2005 Apr;9(2):261-5. [PMID: 15787805]
  • Kinsella JP, Ivy DD, Abman SH. Pulmonary vasodilator therapy in congenital diaphragmatic hernia: acute, late, and chronic pulmonary hypertension. Semin Perinatol. 2005 Apr;29(2):123-8. [PMID: 16052736]
  • Rashid A, Ivy D. New management strategies in sever paediatric pulmonary hypertension. Cardiol Today. 2005 Mar-Apr;9(2):100-8.
  • Yetman AT, Taylor AL, Doran A, Ivy DD. Utility of cardiopulmonary stress testing in assessing disease severity in children with pulmonary arterial hypertension. Am J Cardiol. 2005 Mar 1;95(5):697-9. [PMID: 15721127]
  • Imamura M, Luo B, Limbird J, Vitello A, Oka M, Ivy DD, McMurtry IF, Garat CV, Fallon MB, Carter EP. Hypoxic pulmonary hypertension is prevented in rats with common bile duct ligation. J Appl Physiol. 2005 Feb;98(2):739-47. [PMID: 15516365]
  • Rashid A, Ivy D. Severe paediatric pulmonary hypertension: new management strategies. Arch Dis Child. 2005 Jan;90(1):92-8. [PMID: 15613526]