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Edward J. Hoffenberg, MD

Professor of Pediatrics
 

Director, Program for Pediatric Inflammatory Bowel Diseases

Contact
      E-mail: edward.hoffenberg@childrenscolorado.org

Affiliations
Section of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics
Children's Hospital Colorado

Certifications
Pediatrics, Pediatric Gastroenterology

Edward J. Hoffenberg, MD, earned his medical degree from Case Western Reserve University School of Medicine in Cleveland, Ohio, in 1986. He completed his Pediatric Residency at the Rainbow Babies and Children’s Hospital in Cleveland, Ohio, in 1989. Dr. Hoffenberg completed his Fellowship in Pediatric Gastroenterology and Nutrition in 1992 at the Children’s Hospital of Philadelphia and the University of Pennsylvania School of Medicine. He joined the faculty of the Department of Pediatrics at the University of Colorado School of Medicine and Children’s Hospital Colorado in 1992. He has been Medical Director of the Program for Pediatric Inflammatory Bowel Diseases at Children’s Colorado since 1998.

Dr. Hoffenberg’s research interests include epidemiology and the clinical features of celiac autoimmunity in early childhood, inflammatory bowel disease and inherited polyposis syndromes. He has received grant support for numerous research projects.

Dr. Hoffenberg is a member of many professional organizations and committees. He is a popular invited lecturer nationwide and widely published in medical journals and texts.

  • Scientific Advisory Board, Celiac Disease Initiative, Children's Digestive Health and Nutrition Foundation, 2003-present
  • Liaison Member, North American Society for Pediatric Gastroenterology, Hepatology and Nutrition, World Congress of Pediatric Gastroenterology, Hepatology and Nutrition, Brazil, 2008
  • 5280 Magazine’s Top Doctors in Denver, 2007-2008
  • Chair, International Committee for NASPGHAN, 2004-2007
  • Abstract Reviewer, American Pediatric Society/ Society for Pediatric Research, 2006
  • Moderator of Oral Session, American Pediatric Society/ Society for Pediatric Research, 2006
  • Associate Editor, Journal of Pediatric Gastroenterology and Nutrition, 2001-2006
  • Committee Member, Guidelines for the Diagnosis and Treatment of Celiac Disease in Children, North American Society for Pediatric Gastroenterology, Hepatology and Nutrition, 2003
  • Member, Scientific Advisory Board, Celiac Disease Initiative, Children's Digestive Health and Nutrition Foundation, 2003

Publications in PubMed (partial list)

  • Hoffenberg EJ, Hoffenberg AS, Utterson E. Celiac disease. In: Liacouras CA, Piccoli DA, editors. Bell LM, Series editor. Pediatric gastroenterology. The requisites in pediatrics. St Louis: Mosby/Elsevier, 2008.
  • Liu E, Li M, Emery L, Taki I, Barriga K, Tiberti C, Eisenbarth GS, Rewers MJ, Hoffenberg EJ. Natural history of antibodies to deamidated gliadin peptides and transglutaminase in early childhood celiac disease. J Pediatr Gastroenterol Nutr. 2007 Sep;45(3):293-300. [PMID: 17873740]
  • Simmons JH, Klingensmith GJ, McFann K, Rewers M, Taylor J, Emery LM, Taki I, Vanyi S, Liu E, Hoffenberg EJ. Impact of celiac autoimmunity on children with type 1 diabetes. J Pediatr. 2007 May;150(5):461-6. [PMID: 17452216]
  • Pacheco TR, Scatena LS, Hoffenberg EJ, Gralla J, Lee LA. Cafe au lait macules and juvenile polyps. Pediatr Dermatol. 2007 Apr. [PMID: 17509109]
  • Hoffenberg EJ, Liu E. Celiac disease for the allergist: who and how to screen. Allergy Asthma Proc. 2007 Jan-Feb;28(1):20-4. [PMID: 17390752]
  • Stene LC, Honeyman MC, Hoffenberg EJ, Haas JE, Sokol RJ, Emery L, Taki I, Norris JM, Erlich HA, Eisenbarth GS, Rewers M. Rotavirus infection frequency and risk of celiac disease autoimmunity in early childhood: a longitudinal study. Am J Gastroenterol. 2006 Oct;101(10):2333-40. [PMID: 17032199]
  • Ordonez P, Sondheimer JM, Fidanza S, Wilkening G, Hoffenberg EJ. Long-term outcome of a patient with congenital short bowel syndrome. J Pediatr Gastroenterol Nutr. 2006 May;42(5):576-80. [PMID: 16707984]
  • Keng JA, Hoffenberg E. Critique of a Swedish cohort study of the impact of maternal celiac disease on fetal outcome. J Pediatr Gastroenterol Nutr. 2006 Jan;42(1):123-4. [PMID: 16385273]
  • Condino AA, Hoffenberg EJ, Accurso F, Penvari C, Anthony M, Gralla J, O'Connor JA. Frequency of ASCA seropositivity in children with cystic fibrosis. J Pediatr Gastroenterol Nutr. 2005 Jul;41(1):23-6. [PMID: 15990625]
  • Norris JM, Barriga K, Hoffenberg EJ, Taki I, Miao D, Haas JE, Emery LM, Sokol RJ, Erlich HA, Eisenbarth GS, Rewers M. Risk of celiac disease autoimmunity and timing of gluten introduction in the diet of infants at increased risk of disease. JAMA. 2005 May 18;293(19):2343-51. [PMID: 15900004]
  • Barker JM, Yu J, Yu L, Wang J, Miao D, Bao F, Hoffenberg E, Nelson JC, Gottlieb PA, Rewers M, Eisenbarth GS. Autoantibody "subspecificity" in type 1 diabetes: risk for organ-specific autoimmunity clusters in distinct groups. Diabetes Care. 2005 Apr;28(4):850-5. [PMID: 15793184]
  • Hoffenberg EJ. Should all children be screened for celiac disease? Gastroenterology. 2005 Apr;128(4 Suppl 1):S98-103. [PMID: 15825134]
  • Liu E, Li M, Bao F, Miao D, Rewers MJ, Eisenbarth GS, Hoffenberg EJ. Need for quantitative assessment of transglutaminase autoantibodies for celiac disease in screening-identified children. J Pediatr. 2005 Apr;146(4):494-9. [PMID: 15812452]
  • Condino AA, Fidanza S, Hoffenberg EJ. A home infliximab infusion program. J Pediatr Gastroenterol Nutr. 2005 Jan;40(1):67-9. [PMID: 15625429]
  • Hill ID, Dirks MH, Liptak GS, Colletti RB, Fasano A, Guandalini S, Hoffenberg EJ, Horvath K, Murray JA, Pivor M, Seidman EG; North American Society for Pediatric Gastroenterology, Hepatology and Nutrition. Guideline for the diagnosis and treatment of celiac disease in children: recommendations of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition. J Pediatr Gastroenterol Nutr. 2005 Jan;40(1):1-19. [PMID: 15625418]
  • Iwamoto M, Hoffenberg EJ, Carethers JM, Doctolero R, Tajima A, Sugano K, Franklin WA, Ahnen DJ. Nuclear accumulation of beta-catenin occurs commonly in the epithelial cells of juvenile polyps. Pediatr Res. 2005 Jan;57(1):4-9; discussion 1-3. [PMID: 15557107]