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Evgenia V. Gerasimovskaya, PhD

Assistant Professor of Pediatrics
 

Contact
   Phone: 720-777-1234 (TBD)
   E-mail: (TBD)

Affiliations
Section of Critical Care Medicine, Department of Pediatrics

Certifications

Evgenia V. Gerasimovskaya, PhD, received her doctoral degree in Biochemistry from the Institute of Experimental Cardiology at the Russian Cardiology Research Center in 1994. Dr. Gerasimovskaya was a Research Scholar with the Pulmonary and Critical Care Division of the University of Pennsylvania in 1997. She completed her first postdoctoral fellowship in the Department of Cellular and Molecular Physiology at Yale University School of Medicine in 1998. In 2001, she completed an additional postdoctoral fellowship in the Department of Pediatrics at the University of Colorado School of Medicine and joined the Department of Pediatrics faculty as a Research Associate.

Dr. Gerasimovskaya’s research interests include purinergic signaling pathways in vascular cells, molecular mechanisms of hypoxia-induced ATP (adenosine triphosphate) release, and metabolism of extracellular ATP by ecto-nucleotidases. She also investigates the mechanisms of hypoxic activation of heterotrimeric G proteins, intracellular kinases, as well as Egr-1 transcription factor.

Dr. Gerasimovskaya is widely published and is an invited reviewer for national medical journals. She is a member of the American Thoracic Society, the American Association for the Advancement of Science, the American Society for Biochemistry and Molecular Biology, the American Society for Cell Biology, and the North American Vascular Biology Organization.

Publications in PubMed

  • Gerasimovskaya EV, Woodward HN, Tucker DA, Stenmark KR. Extracellular ATP is a pro-angiogenic factor for pulmonary artery vasa vasorum endothelial cells. Angiogenesis. 2008;11(2):169-82. [PMID: 18071915]
  • Stenmark KR, Gerasimovskaya E, Davie NJ, Frid, MG. Mesenchymal-endothelial interactions in the control of angiogenic, inflammatory and fibrotic responses in the pulmonary circulation. In: Voelkel NF, Rounds S, editors. The pulmonary endothelium. London: John Wiley & Sons; 2008.
  • Davie NJ, Gerasimovskaya EV, Hofmeister SE, Richman AP, Jones PL, Reeves JT, Stenmark KR. Pulmonary artery adventitial fibroblasts cooperate with vasa vasorum endothelial cells to regulate vasa vasorum neovascularization: a process mediated by hypoxia and endothelin-1. Am J Pathol. 2006 Jun;168(6):1793-807. [PMID: 16723696]
  • Stenmark KR, Davie N, Frid M, Gerasimovskaya E, Das M. Role of the adventitia in pulmonary vascular remodeling. Physiology. 2006 Apr;21:134-45. [PMID: 16565479]
  • Gerasimovskaya EV, Davie NJ, Ahmad S, Tucker DA, White CW, Stenmark KR. Extracellular adenosine triphosphate: a potential regulator of vasa vasorum neovascularization in hypoxia-induced pulmonary vascular remodeling. Chest. 2005 Dec;128(6 Suppl):608S-610S. [PMID: 16373860]
  • Banks MF, Gerasimovskaya EV, Tucker DA, Frid MG, Carpenter TC, Stenmark KR. Egr-1 antisense oligonucleotides inhibit hypoxia-induced proliferation of pulmonary artery adventitial fibroblasts. J Appl Physiol. 2005 Feb;98(2):732-8. [PMID: 15475598]
  • Gerasimovskaya EV, Tucker DA, Stenmark KR. Activation of phosphatidylinositol 3-kinase, Akt, and mammalian target of rapamycin is necessary for hypoxia-induced pulmonary artery adventitial fibroblast proliferation. J Appl Physiol. 2005 Feb;98(2):722-31. [PMID: 15501927]
  • Gerasimovskaya EV, Tucker DA, Weiser-Evans M, Wenzlau JM, Klemm DJ, Banks M, Stenmark KR. Extracellular ATP-induced proliferation of adventitial fibroblasts requires phosphoinositide 3-kinase, Akt, mammalian target of rapamycin, and p70 S6 kinase signaling pathways. J Biol Chem. 2005 Jan 21;280(3):1838-48. [PMID: 15522879]