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Vivek Balasubramaniam, MD

Associate Professor of Pediatrics
 

Director, Pediatric Heart Lung Center Laboratory
Associate Director, Pediatric Pulmonology Fellowship Program

Contact
   Phone: 720-777-1234 (TBD)
   E-mail: (TBD)

Affiliations
Section of Pulmonology, Department of Pediatrics
Pediatric Heart Lung Center
Perinatal Research Center
Children's Hospital Colorado

Certifications
Pediatrics, Pediatric Pulmonology

Vivek Balasubramaniam, MD, received his medical degree in 1995 from the University of Pittsburgh School of Medicine. He completed his Pediatric Residency at the Children’s Hospital of Pittsburgh, in 1998, and a dual Fellowship in Pediatric Pulmonary Medicine and Pediatric Critical Care at the University of Colorado School of Medicine and Children’s Hospital Colorado, in 2002. Dr. Balasubramaniam joined the faculty of the Department of Pediatrics at the University of Colorado School of Medicine and Children’s Hospital Colorado in 2003. He is the Director of the Pediatric Heart Lung Center Laboratory.

Dr. Balasubramaniam’s research interest is in the mechanisms underlying lung vascular and alveolar development, especially in response to stress and injury. His focus is on the role of nitric oxide and other factors in the growth and development of blood vessels in the lung. His research holds the promise of helping infants with disorders of lung development. Dr. Balasubramaniam’s research is supported by the NIH.

Dr. Balasubramaniam is published in both professional medical journals and textbooks. He is a sought-after speaker at pulmonary medicine conferences and is a member of several national medical organizations.

  • Pulmonary Representative, SPR Council, 2011-2014

 

  • Kerby GS, Deterding RR, Balasubramaniam V, Sagel SD, Cavanaugh KL, Federico MJ. Respiratory tract and mediastinum. In: Hay WW Jr, Levin MJ, Sondheimer JM, Deterding RR,editors. Current pediatric diagnosis and treatment. 19th ed. New York: McGraw-Hill; 2009.
  • Gien J, Seedorf GJ, Balasubramaniam V, Tseng N, Markham NE, Abman SH. Chronic intrauterine pulmonary hypertension increases endothelial cell rho-kinase activity and impairs angiogenesis in vitro. Am J Physiol Lung Cell Mol Physiol. 2008 Oct;295(4):L680-7. [PMID: 18621906]
  • Abman SA, Baker CD, Balasubramaniam V. Growth and development of the lung circulation: mechanisms and clinical implications. In: Bancalari E, editor. The newborn lung: neonatology questions and controversies. Philadelphia: Saunders; 2008.
  • Muehlethaler V, Kunig AM, Seedorf G, Balasubramaniam V, Abman SH. Impaired VEGF and nitric oxide signaling after nitrofen exposure in rat fetal lung explants. Am J Physiol Lung Cell Mol Physiol. 2008 Jan;294(1):L110-20. [PMID: 17993583]
  • Gien J, Seedorf GJ, Balasubramaniam V, Markham N, Abman SH. Intrauterine pulmonary hypertension impairs angiogenesis in vitro: role of vascular endothelial growth factor nitric oxide signaling. Am J Respir Crit Care Med. 2007 Dec;176(11):1146-53. [PMID: 17823355]
  • Tang JR, Seedorf G, Balasubramaniam V, Maxey A, Markham N, Abman SH. Early inhaled nitric oxide treatment decreases apoptosis of endothelial cells in neonatal rat lungs after vascular endothelial growth factor inhibition. Am J Physiol Lung Cell Mol Physiol. 2007 Nov;293(5):L1271-80. [PMID: 17827251]
  • Balasubramaniam V, Mervis CF, Maxey AM, Markham NE, Abman SH. Hyperoxia reduces bone marrow, circulating, and lung endothelial progenitor cells in the developing lung: implications for the pathogenesis of bronchopulmonary dysplasia. Am J Physiol Lung Cell Mol Physiol. 2007 May;292(5):L1073-84. [PMID: 17209139]
  • Kerby GS, Accurso FJ, Deterding RR, Balasubramaniam V, Sagel SD, Cavanaugh K. Respiratory tract and mediastinum. In: Hay WW Jr, Levin MJ, Sondheimer JM, Deterding RR, editors. Current pediatric diagnosis and treatment. 18th ed. New York: McGraw-Hill; 2007.
  • Kunig AM, Balasubramaniam V, Markham NE, Seedorf G, Gien J, Abman SH. Recombinant human VEGF treatment transiently increases lung edema but enhances lung structure after neonatal hyperoxia. Am J Physiol Lung Cell Mol Physiol. 2006 Nov;291(5):L1068-78. [PMID: 16829629]
  • Balasubramaniam V, Maxey AM, Morgan DB, Markham NE, Abman SH. Inhaled NO restores lung structure in eNOS-deficient mice recovering from neonatal hypoxia. Am J Physiol Lung Cell Mol Physiol. 2006 Jul;291(1):L119-27. [PMID: 16443642]
  • Balasubramaniam V, Maxey AM, Fouty BW, Abman SH. Nitric oxide augments fetal pulmonary artery endothelial cell angiogenesis in vitro. Am J Physiol Lung Cell Mol Physiol. 2006 Jun;290(6):L1111-6. [PMID: 16399787]
  • Deruelle P, Balasubramaniam V, Kunig AM, Seedorf GJ, Markham NE, Abman SH. BAY 41-2272, a direct activator of soluble guanylate cyclase, reduces right ventricular hypertrophy and prevents pulmonary vascular remodeling during chronic hypoxia in neonatal rats. Biol Neonate. 2006;90(2):135-44. [PMID: 16582538]
  • Balasubramaniam V, Maxey A, Abman S. Inhaled nitric oxide reverses hypoxia induced lung hypoplasia in endothelial nitric oxide synthase-deficient mice. Chest. 2005 Dec;128(6 Suppl):613S-614S. [PMID: 16373866]
  • Kunig AM, Balasubramaniam V, Markham NE, Morgan D, Montgomery G, Grover TR, Abman SH. Recombinant human VEGF treatment enhances alveolarization after hyperoxic lung injury in neonatal rats. Am J Physiol Lung Cell Mol Physiol. 2005 Oct;289(4):L529-35. [PMID: 15908474]
  • Stenmark KR, Balasubramaniam V. Angiogenic therapy for bronchopulmonary dysplasia: rationale and promise. Circulation. 2005 Oct 18;112(16):2383-5. [PMID: 16230495]
  • Lin YJ, Markham NE, Balasubramaniam V, Tang JR, Maxey A, Kinsella JP, Abman SH. Inhaled nitric oxide enhances distal lung growth after exposure to hyperoxia in neonatal rats. Pediatr Res. 2005 Jul;58(1):22-9. [PMID: 15879297]
  • Grover TR, Parker TA, Balasubramaniam V, Markham NE, Abman SH. Pulmonary hypertension impairs alveolarization and reduces lung growth in the ovine fetus. Am J Physiol Lung Cell Mol Physiol. 2005 Apr;288(4):L648-54. [PMID: 15579625]
  • Kerby GS, Larsen GL, Accurso FJ, Deterding RR, Balasubramaniam V, Sagel SD. Respiratory tract and mediastinum. In: Hay WW Jr., Levin MJ, Sondheimer JM, Deterding RR, editors. Current pediatric diagnosis and treatment. 17th ed. New York: McGraw-Hill; 2005.