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RMADC Awarded Department of Defense Grant to Study TBI Link to Alzheimer’s


Dr. Potter’s research group, including Dr. Timothy Boyd, was recently awarded a grant from the Department of Defense (DoD) office of the Congressionally Directed Medical Research Programs (CDMRP) to study links between traumatic brain injury (TBI) and Alzheimer’s disease. The highly competitive award will fund a three-year study to develop a rat model for testing the effect(s) of TBI on the development of Alzheimer’s disease. The grant provides $550,000 in direct costs over a three-year funding period. Only three projects were funded at the end of a competitive application process. The overarching goal of this project is to develop an animal model of TBI useful for testing and perfecting interventions, including candidate drugs, aimed at decreasing the effects of TBI both in general and with respect to its association with increased risk of Alzheimer’s disease. Following the completion of this study, our lab and others will use the rat model to test our most promising Alzheimer’s disease drugs to learn whether they may also block the effect(s) of TBI and its impact on Alzheimer’s disease.