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​Faculty O-Z


Franklin O’Donnell, MPAS, PA-C

Instructor

Mr. O’Donnell is originally from Fairbanks, Alaska and attended the University of Puget Sound in Tacoma, Washington where he majored in biochemistry with a minor in French Language. He then went to PA school at the University of Colorado’s Physician Assistant Child Health Associate Program, graduating in 2015 and receiving his NCCPA certification. Mr. O’Donnell recently completed an intensive 13-month hospitalist training program for advanced practice providers at the University of Colorado Hospital within the Hospital Medicine Group.


 

Joanna Poczobutt, PhD

Research Instructor

Dr. Poczobutt’s primary research interest is the role of immune cells in cancer. She has defined and recovered, through the process of multi-marker flow cytometry, several distinct populations of monocytes and macrophages in a mouse model of lung cancer. Furthermore, she has used RNA-sequencing transcriptional profiling to suggest distinct roles of each population. Dr. Poczobutt is also involved in studies examining mouse myeloid cells in chronic fibrotic kidney disease, polycystic kidney disease, and lung inflammatory diseases.

Research Profile












Kathryn Rafferty, MS, NP, RN

Instructor

Ms. Rafferty has clinical expertise in chronic kidney disease, end-stage renal disease, and hemodialysis. She has been with the Division since 2008 and with the University of Colorado Hospital for over 16 years.


Clinical Profile

Research Profile  


 
 




Kameswaran Ravichandran, PhD

Senior Research Instructor

Dr. Ravichandran is an expert in renal anatomy and physiology with a focus on murine model systems. He was the project lead for a study on the role of mTORC1 and mTORC2 complexes signaling and therapeutic interventions in polycystic kidney disease (PKD), and was also the project lead for studies on the pathophysiology of cisplatin-induced acute kidney injury in lung cancer. In addition, Dr. Ravichandran has overseen the generation, establishment, maintenance, and characterization of several PKD rodent models used for pre-clinical trials and sponsored by private industry.

Research Profile




Carlos Roncal

Assistant Research Professor

As a part of his research, Mr. Roncal applies a dehydration model to mice in order to investigate the effects of dehydration on kidney function. He also studies the role of fructokinase for the potential regulation of vasopressin, the effects of uric acid in type-two diabetic nephropathy, and the ways in which fructose and uric acid may affect metabolic syndrome and renal disease in animal models. Mr. Roncal mentors professional research assistants and fellows in the Anschutz Medical Campus labs.

Research Profile









Erik Stites, MD

Assistant Professor

Dr. Stites completed his fellowship training in general nephrology and transplant nephrology at the University of Colorado and subsequently joined the faculty in the Kidney/Pancreas Transplant Program. His primary research interest is the investigation of potential biomarkers in order to better identify and monitor immunologic risks and injuries after a kidney transplant.

Clinical Profile

Research Profile








Isaac Teitelbaum, MD

Professor

Medical Director, Home Dialysis Program

Dr. Teitelbaum, as medical director of the Home Dialysis Program, oversees the care of approximately 50 home-dialysis patients. He serves as president of the International Society for Peritoneal Dialysis and participates in global educational programs on peritoneal dialysis and other areas of nephrology. Dr. Teitelbaum also maintains a small outpatient clinical practice with a focus in glomerular diseases and spends several months each year attending on one of the University’s inpatient consult services. Notably, Dr. Teitelbaum has been named one of Denver’s “Top Doctors” by 5280 Magazine each year since 2008.

Clinical Profile

Research Profile  





Joshua Thurman, MD

Professor

Director of the Glomerulonephritis Program

Dr. Thurman’s primary research interest is the immunologic basis of kidney disease. His laboratory studies the underlying causes of auto-immunity and inflammation; this work has led to the development of several novel anti-inflammatory therapeutic agents. Dr. Thurman’s laboratory has also developed novel radiologic probes to detect and monitor renal inflammation by magnetic resonance imaging and positron emission tomography. He currently oversees the Glomerulonephritis Clinic at the University of Colorado Hospital, which cares for patients with all forms of inflammatory kidney disease, and participates in clinical trials focused on new therapies and diagnostic tools for treating these diseases.

Clinical Profile

Research Profile


Wei Wang, MD

Research Instructor

Dr. Wang was trained as an M.D. and has been actively involved in medical research since 1996. Dr. Wang has worked with polycystic kidney disease groups since 2009 and has been involved in several clinical trials aimed at slowing the disease progression of autosomal dominant polycystic kidney disease in both children and adults. Her primary research interest is in “mechanisms of action” of statins, including cell proliferation/apoptosis and angiogenesis pathways.

Research Profile


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Xiaoxin Wang, PhD

Assistant Research Professor

A long-time medical research scientist, Dr. Wang received formal training in chemistry, biochemistry and neuroscience. His primary research interest is the role of nuclear receptors in metabolism and aging. Dr. Wang collaborates with private industry on preclinical research in order to identify new animal models and new drug targets for potential therapeutics.

Research Profile





Barbara Weis, MA, NP 

Senior Instructor

Ms. Weis has twelve years of clinical experience with chronic kidney diseases (CKD) and renal transplantation. As a part of her philosophy on patient care, Ms. Weis stresses patient education and shared, informed decision-making. She has received awards for her quality of patient care and leadership by the National Kidney Foundation. Her primary research interest is in advanced care planning for CKD patients.

Clinical Profile

Research Profile


Professor

Co-Director of the Consortium for Fibrosis Research and Translation

Dr. Weiser-Evans co-directs the Consortium for Fibrosis Research and Translation, which is an initiative to positively impact human health by better understanding fundamental fibrosis mechanisms, and to serve as a platform for developing transformative therapies that treat fibrotic diseases across organ systems. She is also a member of the admissions committee for the Pharmacology and Integrated Physiology Graduate Programs and chairs the Dean’s Research Advisory Committee, which is composed of a group of senior-level School of Medicine research faculty who advise the Dean and Vice Chancellor for Research on matters related to research.


The Weiser-Evans Lab focuses on research in vascular biology with an emphasis on the role of the vascular smooth muscle cell (SMC) in regulating vessel homeostasis, pathological vascular remodeling, and fibrotic changes reducing vascular compliance.  Ongoing studies use in vivo and in vitro approaches, combined with translational studies in diseased human tissues, to define defects in anti-proliferative and anti-inflammatory processes in these pathologies.  Results from Dr. Weiser-Evans’s lab demonstrate that SMCs are genetically reprogrammed in situ to generate a pool of resident vascular progenitor cells.  The lab is now working to define the functions of SMC-derived stem cells in the maintenance and repair of the vessel wall, as well as to define their role in disease progression so as to determine the therapeutic potential in vascular repair, bioengineering of blood vessels, and the revascularization of ischemic tissues. 

Research Profile

 


Alexander Wiseman, MD

Professor

Medical Director, Kidney and Pancreas Transplant Programs

Dr. Wiseman’s academic interests include transplant therapies for diabetes, organ allocation and utilization, immunosuppressive strategies and emerging therapies.  He has authored over 60 publications and 15 book chapters, and has given over 100 invited lectures, both nationally and internationally. Dr. Wiseman is active in postgraduate and fellowship education for both the American Society of Transplantation and the American Society of Nephrology, and is an associate editor for the American Journal of Transplantation.  His recent leadership roles include: councilor, Board of Directors, AST; chair, AST Grants Executive Committee; Steering Committee member, AST Fellows Symposium on Transplantation Medicine; course chair, ASN Kidney Transplantation Early Program; Joint Planning Committee member, AST/ASN Transplant Nephrology Core Curriculum.


Clinical Profile

Research Profile


 
Zhiying You, MD, PhD

Assistant Research Professor

Dr. You is trained in both medicine (MD) and biostatistics (PhD). He collaborates with investigators, providing statistical support for a variety of research, including clinical trials and epidemiologic studies, while conducting statistical methodological study. Dr. You’s primary research interests include the design, analysis and interpretation of clinical trials and epidemiologic studies, the application of statistical principles and methods in health-related research, and the development of new statistical techniques.  Dr. You is especially interested in cluster randomized trials, longitudinal data analysis, and causal inference. Serving as the biostatistician on many projects, he has extensive experience in study design and data analysis in health-related research. Dr. You has also accumulated valuable experience through his collaborations with investigators in a variety of fields, including clinical and basic medical sciences, preventive medicine and public health science, and health services and policy.