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Aryeh Fischer, MD

Associate Professor of Medicine


​Dr. Aryeh Fischer is Associate Professor of Medicine at the University of Colorado School of Medicine with a primary appointment within the Division of Rheumatology and a secondary appointment in the Division of Pulmonary Sciences and Critical Care Medicine within the Department of Medicine.   
 
His specific area of clinical and research expertise is within systemic sclerosis and autoimmune associated lung diseases, and autoimmune interstitial lung disease in particular. He has developed clinical expertise with patients referred nationally for evaluation of autoimmune lung disease.  Dr. Fischer has served as an invited lecturer on autoimmune and interstitial lung diseases at numerous national and international pulmonary and rheumatology conferences and has numerous original research publications, review articles, and textbook chapters dealing with autoimmune interstitial lung disease.  

 
1994 - 1998           University of Maryland School of Medicine, 
                                Baltimore, MD
 
1998 - 2001           Temple University Hospital; Internal Medicine Internship and Residency
                                Philadelphia, PA
 
2001 - 2002           Temple University Hospital; Chief Medical Resident
                                Philadelphia, PA
 
2002 - 2004           University of Colorado; Rheumatology Fellowship
                                Denver, CO
2004 - 2005                 Instructor, Division of Rheumatology 
                                      National Jewish Health, Denver, CO        
                                      Clinical Instructor, Division of Rheumatology
                                      University of Colorado School of Medicine, Aurora, CO
                                   
2005 - 2011                 Assistant Professor, Division of Rheumatology
                                      National Jewish Health, Denver, CO
                                      University of Colorado School of Medicine, Aurora, CO
                                               
2005 - 2007                 Attending Physician, Scleroderma Clinic
                                      University of Colorado, Aurora, CO
 
2007 – June 2015        Co-Director, Autoimmune Lung Center
                                       National Jewish Health, Denver, CO
 
2011 – June 2015        Associate Professor of Medicine
                                       Department of Medicine, National Jewish Health, Denver, CO     
 
2011 – June 2015        Director, Scleroderma Clinic
                                       University of Colorado, Aurora, CO
 
07/2012 - 06/2013      Acting Chief, Division of Rheumatology
                                       National Jewish Health, Denver, CO
 
01/2013                         Associate Professor of Medicine
                                        University of Colorado School of Medicine, Aurora CO
 
07/2013 – June 2015   Chief, Division of Rheumatology
                                        National Jewish Health, Denver, CO

July 2015 - present       Director, Autoimmune and Fibrotic Lung Disease Treatment Program
                                        Center for Lungs and Breathing 
                                        Division of Rheumatology
                                        Division of Pulmonary Sciences and Critical Care Medicine
                                        Department of Medicine
                                        University of Colorado School of Medicine​
2008 - Present          Medical Advisory Board Member; Colorado Chapter, Scleroderma 
                                    Foundation 

2010 - Present          Faculty for CTD-PAH Simply Speaking CME
 
2010 - 2012               Global Steering Committee Member; Patient Perspectives on Pulmonary 
                                    Arterial Hypertension
 
2011 - 2012               US Steering Committee Member; Patient Perspectives on Pulmonary
                                   Arterial Hypertension
 
2012 - Present           Medical Advisory Board Member; Pulmonary Fibrosis Foundation
 
2012 - Present           Medical Advisory Board Member; National Scleroderma Foundation
 
2012 - Present           Faculty for F1000 in Interstitial Lung Disease Section
 
01/2013 - Present     Arthritis Foundation Colorado Medical and Scientific Committee, Great 
                                    West Region
 
2013 - Present           Faculty for CTD-PAH Impact PH CME
 
2013                           PHA International Conference Scientific Planning Committee
 
2013 - Present            ATS/ERS Task Force Chair; An International Working Group
                                     on Undifferentiated Forms of CTD-ILD
 
2013 - Present            ERS Task Force Member; CTD-ILD Topics
 
2013 - Present            ERS Task Force Member; IPF Clinical Guidelines
​1992                                Cum Laude Graduate, General Honors Program Graduate 
                                         Departmental Honors, Phi Kappa Phi Society
 
2001                                 Chief Medical Resident, Temple University Hospital
 
2002 - 2003                     Research and Education Trainee Award, American College of 
                                          Rheumatology
 
2007                                 Clinician of the Year, Department of Medicine, National Jewish Health
 
2008, 2013, 2014, 2015  Top Doctor - Rheumatology, 5280 Magazine
 
2014                                 “Doctor of the Year”, National Scleroderma Foundation​
Dr. Fischer's research experience is within systemic sclerosis and autoimmune associated lung disease, with particular interest in autoimmune interstitial lung disease. 
 
Representative publications:
 
Fischer A, Chartrand S.  Assessment and management of connective tissue disease-associated interstitial lung disease.  Sarcoidosis Vasc Diffuse Lung Dis. 2015 Jun 22;32(1):2-21. PMID: 26237351
 
Fischer A, Antoniou KM, Brown KK, Cadranel J, Corte TJ, du Bois RM, Lee JS, Leslie KO, Lynch DA, Matteson EL, Mosca M, Noth I, Richeldi L, Strek ME, Swigris JJ, Wells AU, West SG, Collard HR, Cottin V; “ERS/ATS Task Force on Undifferentiated Forms of CTD-ILD”.  An official European Respiratory Society/American Thoracic Society research statement: interstitial pneumonia with autoimmune features. Eur Respir J. 2015 Jul 9. pii: ERJ-00150-2015. doi: 10.1183/13993003.00150-2015. [Epub ahead of print] PMID: 26160873
 
Chartrand S, Fischer A.  Management of connective tissue disease-associated interstitial lung disease.  Rheum Dis Clin North Am. 2015 May;41(2):279-94. doi: 10.1016/j.rdc.2015.01.002. Epub 2015 Feb 3. PMID: 25836643
 
Fischer A, Brown KK.  Interstitial lung disease in undifferentiated forms of connective tissue disease.  Arthritis Care Res (Hoboken). 2015 Jan;67(1):4-11. doi: 10.1002/acr.22394. PMID: 25048539
 
Solomon JJ, Chartrand S, Fischer A. Current approach to connective tissue disease-associated interstitial lung disease.  Curr Opin Pulm Med. 2014 Sep;20(5):449-56. doi: 10.1097/MCP.0000000000000081. PMID: 25022317
 
Fischer A, Cosgrove GP.  Interstitial lung abnormalities in rheumatoid arthritis are common and important. Chest. 2014 Jul;146(1):8-10. doi: 10.1378/chest.14-0030. PMID: 25010956
 
Fischer A1Swigris JJBolster MBChung LCsuka MEDomsic RFrech THinchcliff MHsu VHummers LKGomberg-Maitland MMathai SCSimms RSteen VD. Pulmonary hypertension and interstitial lung disease within PHAROS: impact of extent of fibrosis and pulmonary physiology on cardiac hemodynamic parameters. Clin Exp Rheumatol. 2014 Nov-Dec;32(6 Suppl 86):S-109-14. Epub 2014 Nov 4.
 
Solomon JJ, Fischer A.  Rheumatoid arthritis interstitial lung disease: time to take notice. Respirology. 2014 May;19(4):463-4. doi: 10.1111/resp.12280. Epub 2014 Apr 6.  PMID: 24703236
 
Fischer A, Richeldi L.  Cross-disciplinary collaboration in connective tissue disease-related lung disease.  Semin Respir Crit Care Med. 2014 Apr;35(2):159-65. doi: 10.1055/s-0034-1371530. Epub 2014 Mar 25. PMID: 24668532
 
Fischer A.  Interstitial lung disease in suggestive forms of connective tissue disease.  J Bras Pneumol. 2013 Nov-Dec;39(6):641-3. doi: 10.1590/S1806-37132013000600001.  PMID: 24473756
 
Solomon JJ, Fischer A.  Connective Tissue Disease-Associated Interstitial Lung Disease: A Focused Review.  J Intensive Care Med. 2013 Dec 25. [Epub ahead of print] PMID: 24371251
 
Fischer A, Brown KK, Du Bois RM, Frankel SK, Cosgrove GP, Fernandez-Perez ER, Huie TJ, Krishnamoorthy M, Meehan RT, Olson AL, Solomon JJ, Swigris JJ. Mycophenolate mofetil improves lung function in connective tissue disease-associated interstitial lung disease.  J Rheumatol. 2013 May;40(5):640-6. doi: 10.3899/jrheum.121043. Epub 2013 Mar 1. PMID: 23457378
 
Tourin O, de la Torre Carazo S, Smith DR, Fischer A.  Pulmonary vasculitis as the first manifestation of rheumatoid arthritis.  Respir Med Case Rep. 2013 Feb 5;8:40-2. doi: 10.1016/j.rmcr.2013.01.003. eCollection 2013. PMID: 26029614
 
Olson AL, Brown KK, Fischer A.  Connective tissue disease-associated lung disease.  Immunol Allergy Clin North Am. 2012 Nov;32(4):513-36. doi: 10.1016/j.iac.2012.09.002. PMID: 23102064
 
Lancet. 2012 Aug 18;380(9842):689-98. doi: 10.1016/S0140-6736(12)61079-4. Review. Erratum in: Lancet. 2012 Sep 29;380(9848):1148. PMID: 22901890
 
Fischer A, Solomon JJ, du Bois RM, Deane KD, Olson AL, Fernandez-Perez ER, Huie TJ, Stevens AD, Gill MB, Rabinovitch AM, Lynch DA, Burns DA, Pineiro IS, Groshong SD, Duarte Achcar RD, Brown KK, Martin RJ, Swigris JJ. Lung disease with anti-CCP antibodies but not rheumatoid arthritis or connective tissue disease.  Respir Med. 2012 Jul;106(7):1040-7. doi: 10.1016/j.rmed.2012.03.006. Epub 2012 Apr 12. PMID: 22503074
 
Fischer A, Bull TM, Steen VD. Practical approach to screening for scleroderma-associated pulmonary arterial hypertension.  Arthritis Care Res (Hoboken). 2012 Mar;64(3):303-10. doi: 10.1002/acr.20693.  PMID: 22076819
 
Fischer A, West SG, Swigris JJ, Brown KK, du Bois RM. Connective tissue disease-associated interstitial lung disease: a call for clarification.  Chest. 2010 Aug;138(2):251-6. doi: 10.1378/chest.10-0194. PMID: 20682528
 
Swigris JJ, Yorke J, Sprunger DB, Swearingen C, Pincus T, du Bois RM, Brown KK, Fischer A.  Assessing dyspnea and its impact on patients with connective tissue disease-related interstitial lung disease. Respir Med. 2010 Sep;104(9):1350-5. doi: 10.1016/j.rmed.2010.03.027. Epub 2010 May 14. PMID: 20471238
 
Fischer A, Swigris JJ, du Bois RM, Lynch DA, Downey GP, Cosgrove GP, Frankel SK, Fernandez-Perez ER, Gillis JZ, Brown KK.  Anti-synthetase syndrome in ANA and anti-Jo-1 negative patients presenting with idiopathic interstitial pneumonia.  Respir Med. 2009 Nov;103(11):1719-24. doi: 10.1016/j.rmed.2009.05.001. Epub 2009 Jun 3. PMID: 19497723
 
Fischer A, Swigris JJ, du Bois RM, Groshong SD, Cool CD, Sahin H, Lynch DA, Gillis JZ, Cohen MD, Meehan RT, Brown KK.  Minor salivary gland biopsy to detect primary Sjogren syndrome in patients with interstitial lung disease. Chest. 2009 Oct;136(4):1072-8. doi: 10.1378/chest.08-2839. Epub 2009 May 8. PMID: 19429722
 
Fischer A.  Interstitial lung disease: a rheumatologist's perspective. J Clin Rheumatol. 2009 Mar;15(2):95-9. doi: 10.1097/RHU.0b013e31819b715d. PMID: 19265357
 
Fischer A, Swigris JJ, Groshong SD, Cool CD, Sahin H, Lynch DA, Curran-Everett D, Gillis JZ, Meehan RT, Brown KK.  Clinically significant interstitial lung disease in limited scleroderma: histopathology, clinical features, and survival. Chest. 2008 Sep;134(3):601-5. doi: 10.1378/chest.08-0053. Epub 2008 Apr 10. PMID: 18403656
 
Fischer A, Misumi S, Curran-Everett D, Meehan RT, Ulrich SK, Swigris JJ, Frankel SK, Cosgrove GP, Lynch DA, Brown KK.Pericardial abnormalities predict the presence of echocardiographically defined pulmonary arterial hypertension in systemic sclerosis-related interstitial lung disease. Chest. 2007 Apr;131(4):988-92. PMID: 17426200
 
Fischer A, Meehan RT, Feghali-Bostwick CA, West SG, Brown KK. Unique characteristics of systemic sclerosis sine scleroderma-associated interstitial lung disease.  Chest. 2006 Oct;130(4):976-81. PMID: 17035427
 
Fischer A, Pfalzgraf FJ, Feghali-Bostwick CA, Wright TM, Curran-Everett D, West SG, Brown KK.  Anti-th/to-positivity in a cohort of patients with idiopathic pulmonary fibrosis.  J Rheumatol. 2006 Aug;33(8):1600-5. PMID: 16783860