Ms. Gaydos is a professional research assistant at the University of Colorado who will function as the CoPARC laboratory coordinator. She has been a research technician since 2000, and had been intimately involved in the development of the CoPARC biorepository with Dr. Burnham. She has prior database management expertise for the PhenoGen Informatics website, and has helped to develop a RedCAPS data site for the current biorepository’s use. Moreover, she has utilized the Freezerworks® system to organize human subjects samples for long term storage, including samples from external sites. She will provide primary oversight for protocols relevant to preliminary processing, shipping, and longer term storage of biological specimens from the Denver site as well as external consortium sites.
Laura Gray is a clinical research nurse at the University of Colorado. She has worked in the critical care field for over a decade, and is responsible for on-going clinical research studies at the University of Colorado Hospital, including CoPARC investigations, ARDS network investigations, and investigations relating to the treatment of ICU-associated weakness. Ms. Gray is responsible for assisting in research procedures and protocols on enrolled CoPARC subjects at UCH’s Clinical and Translational Research Center, as well as the burn intensive care unit in this facility.
Carrie Higgins is a clinical research nurse at the University of Colorado. She is an experienced ICU nurse with over 12 years of critical care experience. In addition to her critical care experience, Carrie has been involved with multi-center clinical trials such as ARDS network for 4 years She will be primarily in charge of recruiting research subjects for CoPARC.
Dr. Maloney will serve as the Data and Safety Monitor for CoPARC, and as a member of the data safety/sample sharing committee. He is a co-director of the scientific oversight committee for University of Colorado’s Clinical Translational Research Center, and is himself a translational researcher. Moreover, he has previously interacted with Dr. Burnham for projects involving subjects with alcohol abuse.
Monica McNulty, M.S. is a database developer and data analyst responsible for incorporating the CoPARC AUD and Burn study data collection instruments into the secure web-based software application called REDCap, which is the basis of electronic data collection for these projects. Monica is responsible for ongoing maintenance of the study databases as well as assurance of the highest possible level of data quality. In addition, she will be responsible for exporting of data from the REDCap software and creation of data files for analysis. Monica is available to assist with questions or concerns related to the REDCap software, the data entry process or data quality assurance.
Ms. Mealer is a University of Colorado pulmonary/critical care faculty member, who will serve as the CoPARC regulatory expert. She will ensure clinical data integrity and protocol adherence at clinical consortium sites, and ensure the timeliness of all regulatory aspects of the research. Ms. Mealer is a seasoned project manager with more than a decade of clinical trials management, including multi-site projects, such as the ARDSNetwork. She has advanced expertise in human subjects regulatory requirements and is currently the Co-Chair for the Adult Biomedical Panel B at Colorado Multiple Institutional Review Board (COMIRB).
Dr. Vandivier is a faculty member in the Division of Pulmonary Sciences and Critical Care at the University of Colorado. His research interests focus on the effects of cigarette smoking and COPD on alveolar macrophage function, including alveolar macrophage efferocytosis, and the additional impact of alcohol abuse on these cells’ activities. His long-term research goal is to develop therapies that will improve clearance of apoptotic cells in inflamed airways thereby ameliorating obstructive symptoms and the predisposition to exacerbations among patients who smoke, many of whom have concomitant alcohol use disorders. Dr. Vandivier has previously completed formal training in research bronchoscopy as an intramural investigator at the NIH.